产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Occludin Monoclonal Antibody (OC-3F10)
目录 :
33-1500
规格 :
100微克
价格 :
美国403.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
OC-3F10
反应物种 :
African green monkey, 豚鼠, 仓鼠, 人类, 小鼠, 大鼠, , , pigs , , 家羊, 非洲爪蛙, domestic rabbit, 猕猴
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 400
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 1:5000; 图 4c
  • 免疫组化; African green monkey; 1:100; 图 1d
  • 免疫印迹; African green monkey; 1:5000; 图 4c
Watanabe D, Nakagawa S, Morofuji Y, Tóth A, Vastag M, Aruga J, et al. Characterization of a Primate Blood-Brain Barrier Co-Culture Model Prepared from Primary Brain Endothelial Cells, Pericytes and Astrocytes. Pharmaceutics. 2021;13: pubmed 出版商
  • 免疫组化; 小鼠; 图 7
Sun Y, Wu D, Zeng W, Chen Y, Guo M, Lu B, et al. The Role of Intestinal Dysbacteriosis Induced Arachidonic Acid Metabolism Disorder in Inflammaging in Atherosclerosis. Front Cell Infect Microbiol. 2021;11:618265 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2e
Ngamsri K, Gamper Tsigaras J, Reutershan J, Konrad F. Fractalkine Is Linked to the Necrosome Pathway in Acute Pulmonary Inflammation. Front Med (Lausanne). 2021;8:591790 pubmed 出版商
  • 免疫组化; 小鼠; 图 3c
Vita S, Redell J, Maynard M, Zhao J, Grill R, Dash P, et al. P-glycoprotein Expression Is Upregulated in a Pre-Clinical Model of Traumatic Brain Injury. Neurotrauma Rep. 2020;1:207-217 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 8e
Devraj G, Guérit S, Seele J, Spitzer D, Macas J, Khel M, et al. HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis. Acta Neuropathol. 2020;140:183-208 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2a
Hu H, Hone E, Provencher E, Sprowls S, Farooqi I, Corbin D, et al. MiR-34a Interacts with Cytochrome c and Shapes Stroke Outcomes. Sci Rep. 2020;10:3233 pubmed 出版商
  • 免疫细胞化学; 犬; 图 1d
  • 免疫细胞化学; 人类; 图 2e, 6g, s1a
  • 免疫组化; 人类; 图 1b
Ear J, Saklecha A, Rajapakse N, Choi J, Ghassemian M, Kufareva I, et al. Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions. iScience. 2020;23:100859 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 5b
Benz F, Wichitnaowarat V, Lehmann M, Germano R, Mihova D, Macas J, et al. Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice. elife. 2019;8: pubmed 出版商
  • 免疫组化; 小鼠; 图 2d
Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai M, Nomura E, et al. Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells. Cell Mol Gastroenterol Hepatol. 2019;7:135-156 pubmed 出版商
  • 免疫组化; 人类; 1:40; 图 s1b
DaSilva Arnold S, Kuo C, Davra V, Remache Y, Kim P, Fisher J, et al. ZEB2, a master regulator of the epithelial-mesenchymal transition, mediates trophoblast differentiation. Mol Hum Reprod. 2019;25:61-75 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 5l
Benedicto I, Lehmann G, Ginsberg M, Nolan D, Bareja R, Elemento O, et al. Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors. Nat Commun. 2017;8:15374 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 3b
Yanagida K, Liu C, Faraco G, Galvani S, Smith H, Burg N, et al. Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. Proc Natl Acad Sci U S A. 2017;114:4531-4536 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2b
Prasad S, Sajja R, Kaisar M, Park J, Villalba H, Liles T, et al. Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity. Redox Biol. 2017;12:58-69 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Ni Y, Teng T, Li R, Simonyi A, Sun G, Lee J. TNFα alters occludin and cerebral endothelial permeability: Role of p38MAPK. PLoS ONE. 2017;12:e0170346 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4b
  • 免疫印迹; 人类; 1:1000; 表 3
Sivagurunathan S, Palanisamy K, Arunachalam J, Chidambaram S. Possible role of HIWI2 in modulating tight junction proteins in retinal pigment epithelial cells through Akt signaling pathway. Mol Cell Biochem. 2017;427:145-156 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6a
  • 免疫印迹; 人类; 1:1000; 图 2a
Lin Z, Zhang Y, Xia Y, Xu X, Jiao X, Sun J. Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway. J Biol Chem. 2016;291:26837-26849 pubmed 出版商
  • 免疫组化; 人类; 图 1.1
Majka G, Wiecek G, Sróttek M, Spiewak K, Brindell M, Koziel J, et al. The impact of lactoferrin with different levels of metal saturation on the intestinal epithelial barrier function and mucosal inflammation. Biometals. 2016;29:1019-1033 pubmed
  • 免疫细胞化学; 人类; 2.5 ug/ml; 图 3d
Qian Y, Li C, Jiang A, Ge S, Gu P, Fan X, et al. HIV-1 gp120 Glycoprotein Interacting with Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing Non-integrin (DC-SIGN) Down-Regulates Tight Junction Proteins to Disrupt the Blood Retinal Barrier and Increase Its Permeability. J Biol Chem. 2016;291:22977-22987 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 3a
Wardill H, Bowen J, Van Sebille Y, Secombe K, Coller J, Ball I, et al. TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced Diarrhea. Mol Cancer Ther. 2016;15:2767-2779 pubmed
  • 免疫细胞化学; 犬; 1:200; 图 5
  • 免疫印迹; 犬; 1:1000; 图 8a
Ronaghan N, Shang J, Iablokov V, Zaheer R, Colarusso P, Dion S, et al. The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction. Am J Physiol Gastrointest Liver Physiol. 2016;311:G466-79 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100
Zeller P, Legendre A, Jacques S, Fleury M, Gilard F, Tcherkez G, et al. Hepatocytes cocultured with Sertoli cells in bioreactor favors Sertoli barrier tightness in rat. J Appl Toxicol. 2017;37:287-295 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Zhang Z, Yan J, Shi H. Role of Hypoxia Inducible Factor 1 in Hyperglycemia-Exacerbated Blood-Brain Barrier Disruption in Ischemic Stroke. Neurobiol Dis. 2016;95:82-92 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2f
Clark P, Al Ahmad A, Qian T, Zhang R, Wilson H, Weichert J, et al. Analysis of Cancer-Targeting Alkylphosphocholine Analogue Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model. Mol Pharm. 2016;13:3341-9 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:100; 图 2
Gao Y, Lui W, Lee W, Cheng C. Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep. 2016;6:28589 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 2.5 ug/ml; 图 5
  • 免疫沉淀; 大鼠; 3 ug/ml; 图 5
  • 免疫印迹; 大鼠; 0.5 ug/ml; 图 5
Poon C, Madawala R, Dowland S, Murphy C. Nectin-3 Is Increased in the Cell Junctions of the Uterine Epithelium at Implantation. Reprod Sci. 2016;23:1580-1592 pubmed
  • 免疫组化-石蜡切片; 小鼠; 图 1
Kobayashi K, Tsugami Y, Matsunaga K, Oyama S, Kuki C, Kumura H. Prolactin and glucocorticoid signaling induces lactation-specific tight junctions concurrent with ?-casein expression in mammary epithelial cells. Biochim Biophys Acta. 2016;1863:2006-16 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:300; 图 4
  • 免疫印迹; 小鼠; 1:3000; 图 4
Guerrera D, Shah J, Vasileva E, Sluysmans S, Méan I, Jond L, et al. PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins. J Biol Chem. 2016;291:11016-29 pubmed 出版商
  • 免疫细胞化学; pigs ; 1:100; 图 3
Kwon J, Jeong S, Choi I, Kim N. ADAM10 Is Involved in Cell Junction Assembly in Early Porcine Embryo Development. PLoS ONE. 2016;11:e0152921 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
Wardill H, Gibson R, Van Sebille Y, Secombe K, Logan R, Bowen J. A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options. Exp Biol Med (Maywood). 2016;241:1386-94 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2
Kuehn A, Kletting S, de Souza Carvalho Wodarz C, Repnik U, Griffiths G, Fischer U, et al. Human alveolar epithelial cells expressing tight junctions to model the air-blood barrier. ALTEX. 2016;33:251-60 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 8
Shukla P, Chaudhry K, Mir H, Gangwar R, Yadav N, Manda B, et al. Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. BMC Cancer. 2016;16:189 pubmed 出版商
  • 免疫组化-石蜡切片; 家羊; 1:50; 图 4
Liu H, Garzoni L, Herry C, Durosier L, Cao M, Burns P, et al. Can Monitoring Fetal Intestinal Inflammation Using Heart Rate Variability Analysis Signal Incipient Necrotizing Enterocolitis of the Neonate?. Pediatr Crit Care Med. 2016;17:e165-76 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 1
Shirasago Y, Shimizu Y, Tanida I, Suzuki T, Suzuki R, Sugiyama K, et al. Occludin-Knockout Human Hepatic Huh7.5.1-8-Derived Cells Are Completely Resistant to Hepatitis C Virus Infection. Biol Pharm Bull. 2016;39:839-48 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 6
  • 免疫组化; 小鼠; 1:200; 图 5
Ibrahim A, Mander S, Hussein K, Elsherbiny N, Smith S, Al Shabrawey M, et al. Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration. Oncotarget. 2016;7:8532-45 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 3
Lou N, Takano T, Pei Y, Xavier A, Goldman S, Nedergaard M. Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier. Proc Natl Acad Sci U S A. 2016;113:1074-9 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 4c
  • 免疫印迹; 小鼠; 1:2000; 图 4b
Shi Y, Liu T, Fu J, Xu W, Wu L, Hou A, et al. Vitamin D/VDR signaling attenuates lipopolysaccharide‑induced acute lung injury by maintaining the integrity of the pulmonary epithelial barrier. Mol Med Rep. 2016;13:1186-94 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 2
Kessler M, Hoffmann K, Brinkmann V, Thieck O, Jackisch S, Toelle B, et al. The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Nat Commun. 2015;6:8989 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Nadeem A, Thomas P, Ulf M, Elena N, Anggakusuma A, Mohamed B, et al. Cell culture-derived HCV cannot infect synovial fibroblasts. Sci Rep. 2015;5:18043 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 s2
  • 酶联免疫吸附测定; 人类; 1:50; 图 s2
  • 免疫印迹; 人类; 图 s2
Castro V, Bertrand L, Luethen M, Dabrowski S, Lombardi J, Morgan L, et al. Occludin controls HIV transcription in brain pericytes via regulation of SIRT-1 activation. FASEB J. 2016;30:1234-46 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2
Stebbins M, Wilson H, Canfield S, Qian T, Palecek S, Shusta E. Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells. Methods. 2016;101:93-102 pubmed 出版商
  • 免疫印迹; 人类; 图 1,2,3
Cravo A, Carter E, Erkan M, Harvey E, Furutani Seiki M, MRSNY R. Hippo pathway elements Co-localize with Occludin: A possible sensor system in pancreatic epithelial cells. Tissue Barriers. 2015;3:e1037948 pubmed 出版商
  • 免疫组化; 人类; 5 ug/ml
Wardill H, Logan R, Bowen J, Van Sebille Y, Gibson R. Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer. Support Care Cancer. 2016;24:1779-88 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
Blume C, Reale R, Held M, Millar T, Collins J, Davies D, et al. Temporal Monitoring of Differentiated Human Airway Epithelial Cells Using Microfluidics. PLoS ONE. 2015;10:e0139872 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 2b
Lee J, Tato C, Joyce Shaikh B, Gulen M, Gulan F, Cayatte C, et al. Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability. Immunity. 2015;43:727-38 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2b
Valere K, Rapista A, Eugenin E, Lu W, Chang T. Human Alpha-Defensin HNP1 Increases HIV Traversal of the Epithelial Barrier: A Potential Role in STI-Mediated Enhancement of HIV Transmission. Viral Immunol. 2015;28:609-15 pubmed 出版商
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Brkic M, Balusu S, Van Wonterghem E, Gorlé N, Benilova I, Kremer A, et al. Amyloid β Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases. J Neurosci. 2015;35:12766-78 pubmed 出版商
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Zhao Y, Zhao L, Wang P, Miao Y, Liu Y, Wang Z, et al. Overexpression of miR-18a negatively regulates myocyte enhancer factor 2D to increase the permeability of the blood-tumor barrier via Krüppel-like factor 4-mediated downregulation of zonula occluden-1, claudin-5, and occludin. J Neurosci Res. 2015;93:1891-902 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 3b
Abdayem R, Callejon S, Portes P, Kirilov P, Demarne F, Pirot F, et al. Modulation of transepithelial electric resistance (TEER) in reconstructed human epidermis by excipients known to permeate intestinal tight junctions. Exp Dermatol. 2015;24:686-91 pubmed 出版商
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  • 免疫印迹; 大鼠; 1:500; 图 2a
Cong X, Zhang Y, Li J, Mei M, Ding C, Xiang R, et al. Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells. J Cell Sci. 2015;128:2271-86 pubmed 出版商
  • 免疫细胞化学; 人类; 2.5 ug/ml
Staat C, Coisne C, Dabrowski S, Stamatovic S, Andjelkovic A, Wolburg H, et al. Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers. Biomaterials. 2015;54:9-20 pubmed 出版商
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Wu S, Yi J, Zhang Y, Zhou J, Sun J. Leaky intestine and impaired microbiome in an amyotrophic lateral sclerosis mouse model. Physiol Rep. 2015;3: pubmed 出版商
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Ward C, Schlingmann B, Stecenko A, Guidot D, Koval M. NF-κB inhibitors impair lung epithelial tight junctions in the absence of inflammation. Tissue Barriers. 2015;3:e982424 pubmed 出版商
  • 免疫印迹; 猕猴; 图 s1b
Scull M, Shi C, De Jong Y, Gerold G, Ries M, von Schaewen M, et al. Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice. Hepatology. 2015;62:57-67 pubmed 出版商
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Haarmann A, Nowak E, Deiß A, van der Pol S, Monoranu C, Kooij G, et al. Soluble VCAM-1 impairs human brain endothelial barrier integrity via integrin α-4-transduced outside-in signalling. Acta Neuropathol. 2015;129:639-52 pubmed 出版商
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Bazellières E, Conte V, Elosegui Artola A, Serra Picamal X, Bintanel Morcillo M, Roca Cusachs P, et al. Control of cell-cell forces and collective cell dynamics by the intercellular adhesome. Nat Cell Biol. 2015;17:409-20 pubmed 出版商
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Contreras T, Ricciardi E, Cremonini E, Oteiza P. (-)-Epicatechin in the prevention of tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity. Arch Biochem Biophys. 2015;573:84-91 pubmed 出版商
  • 免疫细胞化学; 犬; 图 6
  • 免疫印迹; 犬; 图 3
Fredriksson K, Van Itallie C, Aponte A, Gucek M, Tietgens A, Anderson J. Proteomic analysis of proteins surrounding occludin and claudin-4 reveals their proximity to signaling and trafficking networks. PLoS ONE. 2015;10:e0117074 pubmed 出版商
  • 免疫组化; 人类
Strick Marchand H, Dusséaux M, Darche S, Huntington N, Legrand N, Masse Ranson G, et al. A novel mouse model for stable engraftment of a human immune system and human hepatocytes. PLoS ONE. 2015;10:e0119820 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Sohet F, Lin C, Munji R, Lee S, Ruderisch N, Soung A, et al. LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. J Cell Biol. 2015;208:703-11 pubmed 出版商
  • 免疫组化-冰冻切片; 人类
Röhl M, Tjernlund A, Mehta S, Pettersson P, Bailey R, Broliden K. Comparable mRNA expression of inflammatory markers but lower claudin-1 mRNA levels in foreskin tissue of HSV-2 seropositive versus seronegative asymptomatic Kenyan young men. BMJ Open. 2015;5:e006627 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Momeny M, Saunus J, Marturana F, McCart Reed A, Black D, Sala G, et al. Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget. 2015;6:3932-46 pubmed
  • 免疫组化; 人类; 1:50
Chajra H, Amstutz B, Schweikert K, Auriol D, Redziniak G, Lefèvre F. Opioid receptor delta as a global modulator of skin differentiation and barrier function repair. Int J Cosmet Sci. 2015;37:386-94 pubmed 出版商
  • 免疫组化; 小鼠
Khairallah H, El Andalousi J, Simard A, Haddad N, Chen Y, Hou J, et al. Claudin-7, -16, and -19 during mouse kidney development. Tissue Barriers. 2014;2:e964547 pubmed 出版商
  • 免疫组化; 豚鼠
Lee S, Kwon J, Choi I, Kim N. Expression and function of transcription factor AP-2? in early embryonic development of porcine parthenotes. Reprod Fertil Dev. 2015;: pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
  • 免疫印迹; 人类
Nicolas V, Liévin Le Moal V. Antisecretory factor peptide AF-16 inhibits the secreted autotransporter toxin-stimulated transcellular and paracellular passages of fluid in cultured human enterocyte-like cells. Infect Immun. 2015;83:907-22 pubmed 出版商
  • 免疫组化; 人类; 1:150
Pienaar I, Lee C, Elson J, McGuinness L, Gentleman S, Kalaria R, et al. Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease. Neurobiol Dis. 2015;74:392-405 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000
Vitiello E, Ferreira J, Maiato H, Balda M, Matter K. The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesion. Nat Commun. 2014;5:5826 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Watari A, Hashegawa M, Yagi K, Kondoh M. Homoharringtonine increases intestinal epithelial permeability by modulating specific claudin isoforms in Caco-2 cell monolayers. Eur J Pharm Biopharm. 2015;89:232-8 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 3
Qiao X, Roth I, Féraille E, Hasler U. Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Cell Cycle. 2014;13:3059-75 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6b
Shirasago Y, Sekizuka T, Saito K, Suzuki T, Wakita T, Hanada K, et al. Isolation and characterization of an Huh.7.5.1-derived cell clone highly permissive to hepatitis C virus. Jpn J Infect Dis. 2015;68:81-8 pubmed 出版商
  • 免疫组化-冰冻切片; 非洲爪蛙; 图 3
Wiechmann A, Ceresa B, Howard E. Diurnal variation of tight junction integrity associates inversely with matrix metalloproteinase expression in Xenopus laevis corneal epithelium: implications for circadian regulation of homeostatic surface cell desquamation. PLoS ONE. 2014;9:e113810 pubmed 出版商
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Szczepkowska A, Lagaraine C, Robert V, Dufourny L, Thiery J, Skipor J. Effect of a two-week treatment with a low dose of 2,2'4,4',5,5'-hexachlorobiphenyl (PCB153) on tight junction protein expression in ovine choroid plexus during long and short photoperiods. Neurotoxicol Teratol. 2013;37:63-7 pubmed 出版商
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Fiorentino M, Lammers K, Levine M, Sztein M, Fasano A. In vitro Intestinal Mucosal Epithelial Responses to Wild-Type Salmonella Typhi and Attenuated Typhoid Vaccines. Front Immunol. 2013;4:17 pubmed 出版商
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Kirschner N, Rosenthal R, Furuse M, Moll I, Fromm M, Brandner J. Contribution of tight junction proteins to ion, macromolecule, and water barrier in keratinocytes. J Invest Dermatol. 2013;133:1161-9 pubmed 出版商
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Kissoon Singh V, Moreau F, Trusevych E, Chadee K. Entamoeba histolytica exacerbates epithelial tight junction permeability and proinflammatory responses in Muc2(-/-) mice. Am J Pathol. 2013;182:852-65 pubmed 出版商
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Takasawa A, Kojima T, Ninomiya T, Tsujiwaki M, Murata M, Tanaka S, et al. Behavior of tricellulin during destruction and formation of tight junctions under various extracellular calcium conditions. Cell Tissue Res. 2013;351:73-84 pubmed 出版商
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Wang J, Novak I. Ion transport in human pancreatic duct epithelium, Capan-1 cells, is regulated by secretin, VIP, acetylcholine, and purinergic receptors. Pancreas. 2013;42:452-60 pubmed 出版商
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Northrop N, Yamamoto B. Persistent neuroinflammatory effects of serial exposure to stress and methamphetamine on the blood-brain barrier. J Neuroimmune Pharmacol. 2012;7:951-68 pubmed 出版商
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Morel A, Hinkal G, Thomas C, Fauvet F, Courtois Cox S, Wierinckx A, et al. EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice. PLoS Genet. 2012;8:e1002723 pubmed 出版商
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Guzman Aranguez A, Woodward A, Pintor J, ARGUESO P. Targeted disruption of core 1 ?1,3-galactosyltransferase (C1galt1) induces apical endocytic trafficking in human corneal keratinocytes. PLoS ONE. 2012;7:e36628 pubmed 出版商
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Kelsey L, Katoch P, Johnson K, Batra S, Mehta P. Retinoids regulate the formation and degradation of gap junctions in androgen-responsive human prostate cancer cells. PLoS ONE. 2012;7:e32846 pubmed 出版商
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Jiang X, Guo M, Su J, Lu B, Ma D, Zhang R, et al. Simvastatin blocks blood-brain barrier disruptions induced by elevated cholesterol both in vivo and in vitro. Int J Alzheimers Dis. 2012;2012:109324 pubmed 出版商
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Dukes J, Whitley P, Chalmers A. The PIKfyve inhibitor YM201636 blocks the continuous recycling of the tight junction proteins claudin-1 and claudin-2 in MDCK cells. PLoS ONE. 2012;7:e28659 pubmed 出版商
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Korompay A, Borka K, Lotz G, Somorácz A, Törzsök P, Erdélyi Belle B, et al. Tricellulin expression in normal and neoplastic human pancreas. Histopathology. 2012;60:E76-86 pubmed 出版商
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Fernandes I, de Freitas V, Reis C, Mateus N. A new approach on the gastric absorption of anthocyanins. Food Funct. 2012;3:508-16 pubmed 出版商
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Kyuno D, Kojima T, Ito T, Yamaguchi H, Tsujiwaki M, Takasawa A, et al. Protein kinase C? inhibitor enhances the sensitivity of human pancreatic cancer HPAC cells to Clostridium perfringens enterotoxin via claudin-4. Cell Tissue Res. 2011;346:369-81 pubmed 出版商
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Nguyen Hoang A, Chen P, Juarez J, Sachamitr P, Billing B, Bosnjak L, et al. Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa. Am J Physiol Lung Cell Mol Physiol. 2012;302:L226-37 pubmed 出版商
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Lan K, Wang Y, Lee W, Lan K, Tseng S, Hung L, et al. Multiple effects of Honokiol on the life cycle of hepatitis C virus. Liver Int. 2012;32:989-97 pubmed 出版商
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Lee S, Shin J, Kwon H, Weiner I, Han K. Renal ischemia-reperfusion injury causes intercalated cell-specific disruption of occludin in the collecting duct. Histochem Cell Biol. 2011;136:637-47 pubmed 出版商
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Chi F, Wang L, Zheng X, Wu C, Jong A, Sheard M, et al. Meningitic Escherichia coli K1 penetration and neutrophil transmigration across the blood-brain barrier are modulated by alpha7 nicotinic receptor. PLoS ONE. 2011;6:e25016 pubmed 出版商
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Carman A, Mills J, Krenz A, Kim D, Bynoe M. Adenosine receptor signaling modulates permeability of the blood-brain barrier. J Neurosci. 2011;31:13272-80 pubmed 出版商
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Lubarski I, Asher C, Garty H. FXYD5 (dysadherin) regulates the paracellular permeability in cultured kidney collecting duct cells. Am J Physiol Renal Physiol. 2011;301:F1270-80 pubmed 出版商
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Quaranta M, Vincentini O, Felli C, Spadaro F, Silano M, Moricoli D, et al. Exogenous HIV-1 Nef upsets the IFN-?-induced impairment of human intestinal epithelial integrity. PLoS ONE. 2011;6:e23442 pubmed 出版商
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Humen M, Perez P, Liévin Le Moal V. Lipid raft-dependent adhesion of Giardia intestinalis trophozoites to a cultured human enterocyte-like Caco-2/TC7 cell monolayer leads to cytoskeleton-dependent functional injuries. Cell Microbiol. 2011;13:1683-702 pubmed 出版商
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Kojima T, Takasawa A, Kyuno D, Ito T, Yamaguchi H, Hirata K, et al. Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells. Exp Cell Res. 2011;317:2288-98 pubmed 出版商
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Dukes J, Fish L, Richardson J, Blaikley E, Burns S, Caunt C, et al. Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells. Mol Biol Cell. 2011;22:3192-205 pubmed 出版商
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Jahn K, Biazik J, Braet F. GM1 expression in caco-2 cells: characterisation of a fundamental passage-dependent transformation of a cell line. J Pharm Sci. 2011;100:3751-62 pubmed 出版商
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Yan J, Zhang Z, Shi H. HIF-1 is involved in high glucose-induced paracellular permeability of brain endothelial cells. Cell Mol Life Sci. 2012;69:115-28 pubmed 出版商
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Lagaraine C, Skipor J, Szczepkowska A, Dufourny L, Thiery J. Tight junction proteins vary in the choroid plexus of ewes according to photoperiod. Brain Res. 2011;1393:44-51 pubmed 出版商
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Kwon Y, Cukierman E, Godwin A. Differential expressions of adhesive molecules and proteases define mechanisms of ovarian tumor cell matrix penetration/invasion. PLoS ONE. 2011;6:e18872 pubmed 出版商
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Butt O, Buehler P, D Agnillo F. Blood-brain barrier disruption and oxidative stress in guinea pig after systemic exposure to modified cell-free hemoglobin. Am J Pathol. 2011;178:1316-28 pubmed 出版商
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Eyre N, Drummer H, Beard M. The SR-BI partner PDZK1 facilitates hepatitis C virus entry. PLoS Pathog. 2010;6:e1001130 pubmed 出版商
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Su L, Mruk D, Lee W, Cheng C. Differential effects of testosterone and TGF-?3 on endocytic vesicle-mediated protein trafficking events at the blood-testis barrier. Exp Cell Res. 2010;316:2945-60 pubmed 出版商
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Cong W, Hirose T, Harita Y, Yamashita A, Mizuno K, Hirano H, et al. ASPP2 regulates epithelial cell polarity through the PAR complex. Curr Biol. 2010;20:1408-14 pubmed 出版商
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Burgel B, Friesland M, Koch A, Manns M, Wedemeyer H, Weissenborn K, et al. Hepatitis C virus enters human peripheral neuroblastoma cells - evidence for extra-hepatic cells sustaining hepatitis C virus penetration. J Viral Hepat. 2011;18:562-70 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 3a
Yamaguchi H, Kojima T, Ito T, Kimura Y, Imamura M, Son S, et al. Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells. Am J Pathol. 2010;177:698-712 pubmed 出版商
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Garay E, Patino Lopez G, Islas S, Alarcón L, Canche Pool E, Valle Rios R, et al. CRTAM: A molecule involved in epithelial cell adhesion. J Cell Biochem. 2010;111:111-22 pubmed 出版商
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  • 免疫印迹; 人类; 1:1000; 图 2
Kojima T, Fuchimoto J, Yamaguchi H, Ito T, Takasawa A, Ninomiya T, et al. c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells. J Cell Physiol. 2010;225:720-33 pubmed 出版商
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De la Serre C, Ellis C, Lee J, Hartman A, Rutledge J, Raybould H. Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation. Am J Physiol Gastrointest Liver Physiol. 2010;299:G440-8 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2a
  • 免疫印迹; 人类; 图 3a
Schubert Unkmeir A, Konrad C, Slanina H, Czapek F, Hebling S, Frosch M. Neisseria meningitidis induces brain microvascular endothelial cell detachment from the matrix and cleavage of occludin: a role for MMP-8. PLoS Pathog. 2010;6:e1000874 pubmed 出版商
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Yakovich A, Huang Q, Du J, Jiang B, Barnard J. Vectorial TGFbeta signaling in polarized intestinal epithelial cells. J Cell Physiol. 2010;224:398-404 pubmed 出版商
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Ciesek S, Steinmann E, Iken M, Ott M, Helfritz F, Wappler I, et al. Glucocorticosteroids increase cell entry by hepatitis C virus. Gastroenterology. 2010;138:1875-84 pubmed 出版商
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Ploss A, Khetani S, Jones C, Syder A, Trehan K, Gaysinskaya V, et al. Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures. Proc Natl Acad Sci U S A. 2010;107:3141-5 pubmed 出版商
  • 免疫组化; 人类; 1:50; 图 2a
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Karim M, Biswas S, Bhattacherjee P, Paterson C. Comparison of tight junction protein expression in the ciliary epithelia of mouse, rabbit, cat and human eyes. Biotech Histochem. 2011;86:161-7 pubmed 出版商
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Chakraborty S, Mitra S, Falk M, Caplan S, Wheelock M, Johnson K, et al. E-cadherin differentially regulates the assembly of Connexin43 and Connexin32 into gap junctions in human squamous carcinoma cells. J Biol Chem. 2010;285:10761-76 pubmed 出版商
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Ohkuni T, Kojima T, Ogasawara N, Masaki T, Ninomiya T, Kikuchi S, et al. Expression and localization of tricellulin in human nasal epithelial cells in vivo and in vitro. Med Mol Morphol. 2009;42:204-11 pubmed 出版商
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  • 免疫印迹; 人类; 1:1000; 图 3
Joannes A, Bonnomet A, Bindels S, Polette M, Gilles C, Burlet H, et al. Fhit regulates invasion of lung tumor cells. Oncogene. 2010;29:1203-13 pubmed 出版商
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Sadowska G, Malaeb S, Stonestreet B. Maternal glucocorticoid exposure alters tight junction protein expression in the brain of fetal sheep. Am J Physiol Heart Circ Physiol. 2010;298:H179-88 pubmed 出版商
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  • 免疫印迹; 人类; 图 4a
Kamekura R, Kojima T, Koizumi J, Ogasawara N, Kurose M, Go M, et al. Thymic stromal lymphopoietin enhances tight-junction barrier function of human nasal epithelial cells. Cell Tissue Res. 2009;338:283-93 pubmed 出版商
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Shimazaki J, Higa K, Kato N, Satake Y. Barrier function of cultivated limbal and oral mucosal epithelial cell sheets. Invest Ophthalmol Vis Sci. 2009;50:5672-80 pubmed 出版商
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Matsumoto M, Oyamada K, Takahashi H, Sato T, Hatakeyama S, Nakayama K. Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways. Proteomics. 2009;9:3549-63 pubmed 出版商
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Nicholson M, Lindsay L, Murphy C. Ovarian hormones control the changing expression of claudins and occludin in rat uterine epithelial cells during early pregnancy. Acta Histochem. 2010;112:42-52 pubmed 出版商
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  • 免疫印迹; 大鼠; 1:300; 图 7
Sobarzo C, Lustig L, Ponzio R, Suescun M, Denduchis B. Effects of di(2-ethylhexyl) phthalate on gap and tight junction protein expression in the testis of prepubertal rats. Microsc Res Tech. 2009;72:868-77 pubmed 出版商
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Waldow T, Witt W, Janke A, Ulmer A, Buzin A, Matschke K. Cell-cell junctions and vascular endothelial growth factor in rat lung as affected by ischemia/reperfusion and preconditioning with inhaled nitric oxide. J Surg Res. 2009;157:30-42 pubmed 出版商
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Murakami T, Felinski E, Antonetti D. Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem. 2009;284:21036-46 pubmed 出版商
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McCaffrey G, Willis C, Staatz W, Nametz N, Quigley C, Hom S, et al. Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress. J Neurochem. 2009;110:58-71 pubmed 出版商
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Alanne M, Pummi K, Heape A, Grenman R, Peltonen J, Peltonen S. Tight junction proteins in human Schwann cell autotypic junctions. J Histochem Cytochem. 2009;57:523-9 pubmed 出版商
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Tian J, Hao L, Chandra P, Jones D, Willams I, Gewirtz A, et al. Dietary glutamine and oral antibiotics each improve indexes of gut barrier function in rat short bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 2009;296:G348-55 pubmed 出版商
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Son S, Kojima T, Decaens C, Yamaguchi H, Ito T, Imamura M, et al. Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells. Histochem Cell Biol. 2009;131:411-24 pubmed 出版商
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  • 免疫印迹; 人类; 图 2a
McLaughlin J, Lambert D, Padfield P, Burt J, O Neill C. The mycotoxin patulin, modulates tight junctions in caco-2 cells. Toxicol In Vitro. 2009;23:83-9 pubmed 出版商
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Sugimoto M, Inoko A, Shiromizu T, Nakayama M, Zou P, Yonemura S, et al. The keratin-binding protein Albatross regulates polarization of epithelial cells. J Cell Biol. 2008;183:19-28 pubmed 出版商
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Hemphill A, Vonlaufen N, Golaz J, Burgener I. Infection of primary canine duodenal epithelial cell cultures with Neospora caninum. J Parasitol. 2009;95:372-80 pubmed 出版商
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Neuhaus W, Wirth M, Plattner V, Germann B, Gabor F, Noe C. Expression of Claudin-1, Claudin-3 and Claudin-5 in human blood-brain barrier mimicking cell line ECV304 is inducible by glioma-conditioned media. Neurosci Lett. 2008;446:59-64 pubmed 出版商
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  • 免疫印迹; 小鼠; 1:1000; 图 6
Chen X, Lan X, Roche I, Liu R, Geiger J. Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum. J Neurochem. 2008;107:1147-57 pubmed 出版商
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Van Hoof D, Braam S, Dormeyer W, Ward van Oostwaard D, Heck A, Krijgsveld J, et al. Feeder-free monolayer cultures of human embryonic stem cells express an epithelial plasma membrane protein profile. Stem Cells. 2008;26:2777-81 pubmed 出版商
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McCaffrey G, Seelbach M, Staatz W, Nametz N, Quigley C, Campos C, et al. Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia. J Neurochem. 2008;106:2395-409 pubmed 出版商
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Bouschbacher M, Bomsel M, Verronèse E, Gofflo S, Ganor Y, Dezutter Dambuyant C, et al. Early events in HIV transmission through a human reconstructed vaginal mucosa. AIDS. 2008;22:1257-66 pubmed 出版商
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Neuhaus W, Plattner V, Wirth M, Germann B, Lachmann B, Gabor F, et al. Validation of in vitro cell culture models of the blood-brain barrier: tightness characterization of two promising cell lines. J Pharm Sci. 2008;97:5158-75 pubmed 出版商
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  • 免疫印迹; domestic rabbit; 图 4
Chen X, Gawryluk J, Wagener J, Ghribi O, Geiger J. Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease. J Neuroinflammation. 2008;5:12 pubmed 出版商
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Takano K, Kojima T, Ogasawara N, Go M, Kikuchi S, Ninomiya T, et al. Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro. J Mol Histol. 2008;39:265-73 pubmed 出版商
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  • 免疫印迹; 犬; 图 3
Paschoud S, Citi S. Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression. Mol Membr Biol. 2008;25:1-13 pubmed
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Lussier C, Babeu J, Auclair B, Perreault N, Boudreau F. Hepatocyte nuclear factor-4alpha promotes differentiation of intestinal epithelial cells in a coculture system. Am J Physiol Gastrointest Liver Physiol. 2008;294:G418-28 pubmed
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Kojima T, Takano K, Yamamoto T, Murata M, Son S, Imamura M, et al. Transforming growth factor-beta induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes. Liver Int. 2008;28:534-45 pubmed
  • 免疫细胞化学; 大鼠; 1:100; 图 1
  • 免疫印迹; 大鼠; 1:1000; 图 1
McCaffrey G, Staatz W, Quigley C, Nametz N, Seelbach M, Campos C, et al. Tight junctions contain oligomeric protein assembly critical for maintaining blood-brain barrier integrity in vivo. J Neurochem. 2007;103:2540-55 pubmed 出版商
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  • 免疫细胞化学; 人类; 图 1d-f
  • 免疫印迹; 人类; 图 2b
Ohnemus U, Kohrmeyer K, Houdek P, Rohde H, Wladykowski E, Vidal S, et al. Regulation of epidermal tight-junctions (TJ) during infection with exfoliative toxin-negative Staphylococcus strains. J Invest Dermatol. 2008;128:906-16 pubmed
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  • 免疫印迹; 人类; 图 4
Dhasarathy A, Kajita M, Wade P. The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha. Mol Endocrinol. 2007;21:2907-18 pubmed
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Mandell K, Berglin L, Severson E, Edelhauser H, Parkos C. Expression of JAM-A in the human corneal endothelium and retinal pigment epithelium: localization and evidence for role in barrier function. Invest Ophthalmol Vis Sci. 2007;48:3928-36 pubmed
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Moser L, Carter M, Schultz Cherry S. Astrovirus increases epithelial barrier permeability independently of viral replication. J Virol. 2007;81:11937-45 pubmed
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Golaz J, Vonlaufen N, Hemphill A, Burgener I. Establishment and characterization of a primary canine duodenal epithelial cell culture. In Vitro Cell Dev Biol Anim. 2007;43:176-85 pubmed
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Morgan L, Shah B, Rivers L, Barden L, Groom A, Chung R, et al. Inflammation and dephosphorylation of the tight junction protein occludin in an experimental model of multiple sclerosis. Neuroscience. 2007;147:664-73 pubmed
  • 免疫细胞化学; 人类; 1:200; 图 1
  • 免疫印迹; 人类; 1:500; 图 3
Beau I, Cotte Laffitte J, Amsellem R, Servin A. A protein kinase A-dependent mechanism by which rotavirus affects the distribution and mRNA level of the functional tight junction-associated protein, occludin, in human differentiated intestinal Caco-2 cells. J Virol. 2007;81:8579-86 pubmed
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Hernandez S, Chavez Munguia B, Gonzalez Mariscal L. ZO-2 silencing in epithelial cells perturbs the gate and fence function of tight junctions and leads to an atypical monolayer architecture. Exp Cell Res. 2007;313:1533-47 pubmed
  • 免疫细胞化学; 人类; 1:200; 图 6D
Stucke V, Timmerman E, Vandekerckhove J, Gevaert K, Hall A. The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation. Mol Biol Cell. 2007;18:1744-55 pubmed
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Mitra S, Annamalai L, Chakraborty S, Johnson K, Song X, Batra S, et al. Androgen-regulated formation and degradation of gap junctions in androgen-responsive human prostate cancer cells. Mol Biol Cell. 2006;17:5400-16 pubmed
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Anstrom J, Thore C, Moody D, Brown W. Immunolocalization of tight junction proteins in blood vessels in human germinal matrix and cortex. Histochem Cell Biol. 2007;127:205-13 pubmed
  • 免疫组化-石蜡切片; domestic rabbit; 10,000 ug/ml; 图 3d
Uchino Y, Shimmura S, Miyashita H, Taguchi T, Kobayashi H, Shimazaki J, et al. Amniotic membrane immobilized poly(vinyl alcohol) hybrid polymer as an artificial cornea scaffold that supports a stratified and differentiated corneal epithelium. J Biomed Mater Res B Appl Biomater. 2007;81:201-6 pubmed
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Larre I, Ponce A, Fiorentino R, Shoshani L, Contreras R, Cereijido M. Contacts and cooperation between cells depend on the hormone ouabain. Proc Natl Acad Sci U S A. 2006;103:10911-6 pubmed
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Herouy Y, Kahle B, Idzko M, Eberth I, Norgauer J, Pannier F, et al. Tight junctions and compression therapy in chronic venous insufficiency. Int J Mol Med. 2006;18:215-9 pubmed
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Gonzalez Mariscal L, Namorado M, Martin D, Sierra G, Reyes J. The tight junction proteins claudin-7 and -8 display a different subcellular localization at Henle's loops and collecting ducts of rabbit kidney. Nephrol Dial Transplant. 2006;21:2391-8 pubmed
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Watson C, Hoare C, Garrod D, Carlson G, Warhurst G. Interferon-gamma selectively increases epithelial permeability to large molecules by activating different populations of paracellular pores. J Cell Sci. 2005;118:5221-30 pubmed
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Zhu L, Li X, Zeng R, Gorodeski G. Changes in tight junctional resistance of the cervical epithelium are associated with modulation of content and phosphorylation of occludin 65-kilodalton and 50-kilodalton forms. Endocrinology. 2006;147:977-89 pubmed
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Schierack P, Nordhoff M, Pollmann M, Weyrauch K, Amasheh S, Lodemann U, et al. Characterization of a porcine intestinal epithelial cell line for in vitro studies of microbial pathogenesis in swine. Histochem Cell Biol. 2006;125:293-305 pubmed
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Miyashita H, Shimmura S, Kobayashi H, Taguchi T, Asano Kato N, Uchino Y, et al. Collagen-immobilized poly(vinyl alcohol) as an artificial cornea scaffold that supports a stratified corneal epithelium. J Biomed Mater Res B Appl Biomater. 2006;76:56-63 pubmed
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Haton C, Lebrun F, Benderitter M, Griffiths N. Maintenance of differentiation capacity of HT-29 cells after radiation exposure. Int J Radiat Biol. 2005;81:211-20 pubmed
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Clark E, Hoare C, Tanianis Hughes J, Carlson G, Warhurst G. Interferon gamma induces translocation of commensal Escherichia coli across gut epithelial cells via a lipid raft-mediated process. Gastroenterology. 2005;128:1258-67 pubmed
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  • 免疫印迹; African green monkey; 图 4
  • 免疫印迹; 仓鼠; 图 4
  • 免疫印迹; 人类; 图 4
Bordin M, D Atri F, Guillemot L, Citi S. Histone deacetylase inhibitors up-regulate the expression of tight junction proteins. Mol Cancer Res. 2004;2:692-701 pubmed
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Go M, Kojima T, Takano K, Murata M, Ichimiya S, Tsubota H, et al. Expression and function of tight junctions in the crypt epithelium of human palatine tonsils. J Histochem Cytochem. 2004;52:1627-38 pubmed
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Somosy Z, Forgacs Z, Bognár G, Horvath K, Horváth G. Alteration of tight and adherens junctions on 50-Hz magnetic field exposure in Madin Darby canine kidney (MDCK) cells. ScientificWorldJournal. 2004;4 Suppl 2:75-82 pubmed
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  • 免疫细胞化学; 人类; 图 4
  • 免疫印迹; 人类; 图 7
Zeng R, Li X, Gorodeski G. Estrogen abrogates transcervical tight junctional resistance by acceleration of occludin modulation. J Clin Endocrinol Metab. 2004;89:5145-55 pubmed
  • 免疫细胞化学; 犬; 图 8
Sundberg U, Beauchemin N, Obrink B. The cytoplasmic domain of CEACAM1-L controls its lateral localization and the organization of desmosomes in polarized epithelial cells. J Cell Sci. 2004;117:1091-104 pubmed
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Kahle B, Idzko M, Norgauer J, Rabe E, Herouy Y. Tightening tight junctions with compression therapy. J Invest Dermatol. 2003;121:1228-9 pubmed
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Billings S, Walsh S, Fisher C, Nusrat A, Weiss S, Folpe A. Aberrant expression of tight junction-related proteins ZO-1, claudin-1 and occludin in synovial sarcoma: an immunohistochemical study with ultrastructural correlation. Mod Pathol. 2004;17:141-9 pubmed
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Malminen M, Koivukangas V, Peltonen J, Karvonen S, Oikarinen A, Peltonen S. Immunohistological distribution of the tight junction components ZO-1 and occludin in regenerating human epidermis. Br J Dermatol. 2003;149:255-60 pubmed
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Evans S, Blyth D, Wong T, Sanjar S, West M. Decreased distribution of lung epithelial junction proteins after intratracheal antigen or lipopolysaccharide challenge: correlation with neutrophil influx and levels of BALF sE-cadherin. Am J Respir Cell Mol Biol. 2002;27:446-54 pubmed
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Tavelin S, Gråsjö J, Taipalensuu J, Ocklind G, Artursson P. Applications of epithelial cell culture in studies of drug transport. Methods Mol Biol. 2002;188:233-72 pubmed
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Busch C, Hanssen T, Wagener C, Obrink B. Down-regulation of CEACAM1 in human prostate cancer: correlation with loss of cell polarity, increased proliferation rate, and Gleason grade 3 to 4 transition. Hum Pathol. 2002;33:290-8 pubmed
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Gudjonsson T, Villadsen R, Nielsen H, Rønnov Jessen L, Bissell M, Petersen O. Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties. Genes Dev. 2002;16:693-706 pubmed
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Gudjonsson T, Rønnov Jessen L, Villadsen R, Rank F, Bissell M, Petersen O. Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. J Cell Sci. 2002;115:39-50 pubmed
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  • 免疫印迹; 人类; 图 1
Pummi K, Malminen M, Aho H, Karvonen S, Peltonen J, Peltonen S. Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes. J Invest Dermatol. 2001;117:1050-8 pubmed
Rajput S, Liang S, Wang X, Yan H. Lycopene Protects Intestinal Epithelium from Deoxynivalenol-Induced Oxidative Damage via Regulating Keap1/Nrf2 Signaling. Antioxidants (Basel). 2021;10: pubmed 出版商
Zapatero Belinchón F, Ötjengerdes R, Sheldon J, Schulte B, Carriquí Madroñal B, Brogden G, et al. Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity. Cells. 2021;10: pubmed 出版商
Guha S, Alvarez S, Majumder K. Transport of Dietary Anti-Inflammatory Peptide, γ-Glutamyl Valine (γ-EV), across the Intestinal Caco-2 Monolayer. Nutrients. 2021;13: pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
Occludin Monoclonal Antibody (OC-3F10)
目录# :
33-1500
规格 :
100微克
价格 :
美国403.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
狗, 人类, 小鼠, 大鼠
应用 :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 2-3 µg/mL, Western Blot: 0.1-1.0 µg/mL
物种 :
狗, 人类, 小鼠, 大鼠
克隆 :
OC-3F10
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa. Occludin is thought to be involved in regulating both the localization and the function of occludin. Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution. Overall structural features of the occludin protein are highly conserved in all the species examined. Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.
免疫原 :
GST fusion protein consisting of the C-terminal region (~150aa) of human occludin.
格式 :
液体
应用w/稀释 :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 2-3 µg/mL, Western Blot: 0.1-1.0 µg/mL
别名 :
AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国