产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
核纤层蛋白B1单克隆抗体(L-5)
目录 :
33-2000
规格 :
100微克
价格 :
美国398.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
L-5
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 55
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 6a
Ma S, Wan X, Deng Z, Shi L, Hao C, Zhou Z, et al. Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs. J Exp Med. 2017;214:1471-1491 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Walker E, Jensen L, Croft S, Wei K, Fulcher A, Jans D, et al. Rhinovirus 16 2A Protease Affects Nuclear Localization of 3CD during Infection. J Virol. 2016;90:11032-11042 pubmed
  • 免疫印迹; 犬; 1:500; 图 6a
Wetzel F, Mittag S, Cano Cortina M, Wagner T, Kramer O, Niedenthal R, et al. SUMOylation regulates the intracellular fate of ZO-2. Cell Mol Life Sci. 2017;74:373-392 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s5
Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, et al. A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity. Nat Commun. 2016;7:11903 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2a
De Marco G, Lomartire A, Calvo A, Risso A, De Luca E, Mostert M, et al. Monocytes of patients with amyotrophic lateral sclerosis linked to gene mutations display altered TDP-43 subcellular distribution. Neuropathol Appl Neurobiol. 2017;43:133-153 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, et al. Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism. Mol Cell Biol. 2016;36:1655-72 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Rhee M, Lee S, Kim J, Ham D, Park H, Yang H, et al. Preadipocyte factor 1 induces pancreatic ductal cell differentiation into insulin-producing cells. Sci Rep. 2016;6:23960 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1
  • 免疫印迹; 小鼠; 图 1
Rolyan H, Tyurina Y, Hernandez M, Amoscato A, Sparvero L, Nmezi B, et al. Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression. J Neurosci. 2015;35:12002-17 pubmed 出版商
  • 免疫印迹; 小鼠
He L, Zang A, Du M, Ma D, Yuan C, Zhou C, et al. mTOR regulates TLR-induced c-fos and Th1 responses to HBV and HCV vaccines. Virol Sin. 2015;30:174-89 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Korotkevych N, Labyntsev A, Kolybo D, Komisarenko S. The Soluble Heparin-Binding EGF-Like Growth Factor Stimulates EGF Receptor Trafficking to the Nucleus. PLoS ONE. 2015;10:e0127887 pubmed 出版商
  • 免疫印迹; 小鼠
Galvagni F, Lentucci C, Neri F, Dettori D, De Clemente C, Orlandini M, et al. Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes. Stem Cells. 2015;33:742-50 pubmed 出版商
  • 免疫印迹; 人类
Kim H, Li A, Ahn S, Song H, Zhang W. Inositol Polyphosphate-5-Phosphatase F (INPP5F) inhibits STAT3 activity and suppresses gliomas tumorigenicity. Sci Rep. 2014;4:7330 pubmed 出版商
  • 免疫印迹; 人类
Trembley J, Unger G, Korman V, Abedin M, Nacusi L, Vogel R, et al. Tenfibgen ligand nanoencapsulation delivers bi-functional anti-CK2 RNAi oligomer to key sites for prostate cancer targeting using human xenograft tumors in mice. PLoS ONE. 2014;9:e109970 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Tavares E, Maldonado R, Miñano F. Immunoneutralization of endogenous aminoprocalcitonin attenuates sepsis-induced acute lung injury and mortality in rats. Am J Pathol. 2014;184:3069-83 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Li M, Pettitt S, Eckert S, Ning Z, Rice S, Cadinanos J, et al. The piggyBac transposon displays local and distant reintegration preferences and can cause mutations at noncanonical integration sites. Mol Cell Biol. 2013;33:1317-30 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Hassan M, Maeda Y, Taipaleenmaki H, Zhang W, Jafferji M, Gordon J, et al. miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells. J Biol Chem. 2012;287:42084-92 pubmed 出版商
  • 免疫印迹; 大鼠; 图 9
Inoue K, Matsui I, Hamano T, Fujii N, Shimomura A, Nakano C, et al. Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3. Lab Invest. 2012;92:1686-97 pubmed 出版商
  • 免疫印迹; 人类; 1:100; 图 4
Neumann L, Markaki Y, Mladenov E, Hoffmann D, Buiting K, Horsthemke B. The imprinted NPAP1/C15orf2 gene in the Prader-Willi syndrome region encodes a nuclear pore complex associated protein. Hum Mol Genet. 2012;21:4038-48 pubmed 出版商
  • 免疫组化; 大鼠; 1:100; 图 1
  • 免疫印迹; 大鼠; 1:100; 图 5
Wakabayashi T, Mori T, Hirahara Y, Koike T, Kubota Y, Takamori Y, et al. Nuclear lamins are differentially expressed in retinal neurons of the adult rat retina. Histochem Cell Biol. 2011;136:427-36 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Abel E, Bubel J, Simper M, Powell L, McClellan S, Andreeff M, et al. Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway. Toxicol Appl Pharmacol. 2011;255:176-83 pubmed 出版商
  • 免疫印迹; 人类; 图 1
De Marco G, Lupino E, Calvo A, Moglia C, Buccinnà B, Grifoni S, et al. Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations. Acta Neuropathol. 2011;121:611-22 pubmed 出版商
  • 免疫印迹; 人类; 图 8
Lupino E, Buccinnà B, Ramondetti C, Lomartire A, De Marco G, Ricotti E, et al. In CD28-costimulated human naïve CD4+ T cells, I-?B kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms. Immunology. 2010;131:231-41 pubmed 出版商
  • 免疫印迹; 小鼠
Kim K, Yoon Y, Lee H, Yoon S, Kim S, Shin S, et al. Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors. J Biol Chem. 2010;285:8905-17 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Honma K, Tsuzuki S, Nakagawa M, Tagawa H, Nakamura S, Morishima Y, et al. TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas. Blood. 2009;114:2467-75 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Giordana M, Piccinini M, Grifoni S, De Marco G, Vercellino M, Magistrello M, et al. TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis. Brain Pathol. 2010;20:351-60 pubmed 出版商
  • 免疫印迹; 人类; 1:100; 图 4
Joung E, Li M, Lee H, Somparn N, Jung Y, Na H, et al. Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target. Antioxid Redox Signal. 2007;9:2087-98 pubmed
  • 免疫印迹; 大鼠
Li M, Jang J, Na H, Cha Y, Surh Y. Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. J Biol Chem. 2007;282:28577-86 pubmed
  • 免疫印迹; 小鼠; 图 4
Niida H, Katsuno Y, Banerjee B, Hande M, Nakanishi M. Specific role of Chk1 phosphorylations in cell survival and checkpoint activation. Mol Cell Biol. 2007;27:2572-81 pubmed
  • 免疫印迹; 小鼠; 1:1000; 图 1
Ghanem L, Steinman R. A proapoptotic function of p21 in differentiating granulocytes. Leuk Res. 2005;29:1315-23 pubmed
  • 免疫印迹; 犬; 1:500; 图 1
Jaramillo B, Ponce A, Moreno J, Betanzos A, Huerta M, Lopez Bayghen E, et al. Characterization of the tight junction protein ZO-2 localized at the nucleus of epithelial cells. Exp Cell Res. 2004;297:247-58 pubmed
  • 免疫印迹; 犬; 1:500; 图 8
Betanzos A, Huerta M, Lopez Bayghen E, Azuara E, Amerena J, Gonzalez Mariscal L. The tight junction protein ZO-2 associates with Jun, Fos and C/EBP transcription factors in epithelial cells. Exp Cell Res. 2004;292:51-66 pubmed
  • 免疫组化-石蜡切片; 人类; 1:1000; 图 2C
  • 免疫印迹; 人类; 图 1
Oguchi M, Sagara J, Matsumoto K, Saida T, Taniguchi S. Expression of lamins depends on epidermal differentiation and transformation. Br J Dermatol. 2002;147:853-8 pubmed
Perrigue P, Rakoczy M, Pawlicka K, Belter A, Giel Pietraszuk M, Naskret Barciszewska M, et al. Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts. Cancers (Basel). 2020;12: pubmed 出版商
Fassmannová D, Sedlák F, Sedlacek J, Spicka I, Grantz Sasková K. Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma. Cancers (Basel). 2020;12: pubmed 出版商
Amaya E, Alarcón L, Martín Tapia D, Cuellar Perez F, Cano Cortina M, Ortega Olvera J, et al. Activation of the Ca2+ sensing receptor and the PKC/WNK4 downstream signaling cascade induces incorporation of ZO-2 to tight junctions and its separation from 14-3-3. Mol Biol Cell. 2019;30:2377-2398 pubmed 出版商
Kim W, An H, Kim J, Gwon M, Gu H, Jeon M, et al. Anti-Inflammatory Effect of Melittin on Porphyromonas Gingivalis LPS-Stimulated Human Keratinocytes. Molecules. 2018;23: pubmed 出版商
Maclean K, Jiang H, Aivazidis S, Kim E, Shearn C, Harris P, et al. Taurine treatment prevents derangement of the hepatic γ-glutamyl cycle and methylglyoxal metabolism in a mouse model of classical homocystinuria: regulatory crosstalk between thiol and sulfinic acid metabolism. FASEB J. 2018;32:1265-1280 pubmed 出版商
Kim W, An H, Kim J, Gwon M, Gu H, Park J, et al. Bee Venom Inhibits Porphyromonas gingivalis Lipopolysaccharides-Induced Pro-Inflammatory Cytokines through Suppression of NF-κB and AP-1 Signaling Pathways. Molecules. 2016;21: pubmed
Takahara T, Matsuo K, Seto M, Nakamura S, Tsuzuki S. Synergistic activity of Card11 mutant and Bcl6 in the development of diffuse large B-cell lymphoma in a mouse model. Cancer Sci. 2016;107:1572-1580 pubmed 出版商
Shah V, Aiken C. Cell Fractionation and Quantitative Analysis of HIV-1 Reverse Transcription in Target Cells. Bio Protoc. 2013;3: pubmed
Chou T, Chuang Y, Hsieh W, Chang P, Liu H, Mo S, et al. Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1? for Th17 suppression. Nat Commun. 2016;7:11904 pubmed 出版商
Goretsky T, Bradford E, Ryu H, Tahir M, Moyer M, Gao T, et al. A Cytosolic Multiprotein Complex Containing p85α Is Required for β-Catenin Activation in Colitis and Colitis-associated Cancer. J Biol Chem. 2016;291:4166-77 pubmed 出版商
Majkut S, Idema T, Swift J, Krieger C, Liu A, Discher D. Heart-specific stiffening in early embryos parallels matrix and myosin expression to optimize beating. Curr Biol. 2013;23:2434-9 pubmed 出版商
Hinoi E, Nakamura Y, Takada S, Fujita H, Iezaki T, Hashizume S, et al. Growth differentiation factor-5 promotes brown adipogenesis in systemic energy expenditure. Diabetes. 2014;63:162-75 pubmed 出版商
Quirós M, Alarcón L, Ponce A, Giannakouros T, Gonzalez Mariscal L. The intracellular fate of zonula occludens 2 is regulated by the phosphorylation of SR repeats and the phosphorylation/O-GlcNAcylation of S257. Mol Biol Cell. 2013;24:2528-43 pubmed 出版商
Chort A, Alves S, Marinello M, Dufresnois B, Dornbierer J, Tesson C, et al. Interferon ? induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice. Brain. 2013;136:1732-45 pubmed 出版商
Tsuchiya Y, Morita T, Kim M, Iemura S, Natsume T, Yamamoto M, et al. Dual regulation of the transcriptional activity of Nrf1 by ?-TrCP- and Hrd1-dependent degradation mechanisms. Mol Cell Biol. 2011;31:4500-12 pubmed 出版商
Trembley J, Unger G, Tobolt D, Korman V, Wang G, Ahmad K, et al. Systemic administration of antisense oligonucleotides simultaneously targeting CK2? and ?' subunits reduces orthotopic xenograft prostate tumors in mice. Mol Cell Biochem. 2011;356:21-35 pubmed 出版商
Li X, Liang D, Lin X, Robertson E, Lan K. Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen reduces interleukin-8 expression in endothelial cells and impairs neutrophil chemotaxis by degrading nuclear p65. J Virol. 2011;85:8606-15 pubmed 出版商
Fulcher A, Roth D, Fatima S, Alvisi G, Jans D. The BRCA-1 binding protein BRAP2 is a novel, negative regulator of nuclear import of viral proteins, dependent on phosphorylation flanking the nuclear localization signal. FASEB J. 2010;24:1454-66 pubmed 出版商
Arts J, King P, Marien A, Floren W, Beliën A, Janssen L, et al. JNJ-26481585, a novel "second-generation" oral histone deacetylase inhibitor, shows broad-spectrum preclinical antitumoral activity. Clin Cancer Res. 2009;15:6841-51 pubmed 出版商
Civelek M, Manduchi E, Riley R, Stoeckert C, Davies P. Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis. Circ Res. 2009;105:453-61 pubmed 出版商
Chandraskeharan K, Martin P. Embryonic overexpression of Galgt2 inhibits skeletal muscle growth via activation of myostatin signaling. Muscle Nerve. 2009;39:25-41 pubmed 出版商
Vradii D, Zaidi S, Lian J, Van Wijnen A, Stein J, Stein G. Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype. Proc Natl Acad Sci U S A. 2005;102:7174-9 pubmed
Zhang L, Shimizu S, Tsujimoto Y. Two distinct Fas-activated signaling pathways revealed by an antitumor drug D609. Oncogene. 2005;24:2954-62 pubmed
产品信息
产品类型 :
抗体
产品名称 :
核纤层蛋白B1单克隆抗体(L-5)
目录# :
33-2000
规格 :
100微克
价格 :
美国398.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
鸡, 人类, 小鼠, 大鼠
应用 :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5-10 µg/mL, Immunoprecipitation: 2.5-5 µg, Western Blot: 2 µg/mL
物种 :
鸡, 人类, 小鼠, 大鼠
克隆 :
L-5
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Defects in the LMNB1 gene can cause Leukodystrophy, demyelinating, autosomal dominant, adult-onset (ADLD).
免疫原 :
Extracts from chicken nuclei
格式 :
液体
应用w/稀释 :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5-10 µg/mL, Immunoprecipitation: 2.5-5 µg, Western Blot: 2 µg/mL
别名 :
0710005A05Rik; ADLD; C-flanking peptide of NPY; CPON; fc06g01; I79_003938; lamin B1; lamin B1 L homeolog; lamin B1 protein; lamin-b; lamin-B1; Lamin-L(I); LMN; LMN2; LMNB; LMNB1; lmnb1 protein; lmnb1.L; MGC111419; Neuropeptide tyrosine; Neuropeptide Y; NPY; NPY02; prepro-neuropeptide Y; pro-neuropeptide Y; PYY4; RATNPY; RATNPY02; unnamed protein product; wu:fc06g01; XELAEV_18007951mg
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国