产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(4A2C7)
目录 :
33-4000
规格 :
100微克
价格 :
美国452.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4A2C7
反应物种 :
Japanese crane, Clostridioides difficile, black ferret, 人类, 小鼠, 大鼠, , pigs , 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 215
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 人类; 图 2
Hering H, Zoschke C, Kühn M, Gadicherla A, Weindl G, Luch A, et al. TatS: a novel in vitro tattooed human skin model for improved pigment toxicology research. Arch Toxicol. 2020;94:2423-2434 pubmed 出版商
  • 免疫组化; 人类; 1:50; 图 s t3
Christgen M, Bartels S, van Luttikhuizen J, Bublitz J, Rieger L, Christgen H, et al. E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements. Mod Pathol. 2020;33:2483-2498 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 1f
Kim Y, You H, Park S, Kim M, Chae H, Park J, et al. A Mutation in ZNF143 as a Novel Candidate Gene for Endothelial Corneal Dystrophy. J Clin Med. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 4e
Hayward A, Aird E, Gordon W. A toolkit for studying cell surface shedding of diverse transmembrane receptors. elife. 2019;8: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2e
Xue X, Bredell B, Anderson E, Martin A, Mays C, Nagao Kitamoto H, et al. Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017;114:E9608-E9617 pubmed 出版商
  • 免疫组化; 人类; 表 1
Morandi L, Righi A, Maletta F, Rucci P, Pagni F, Gallo M, et al. Somatic mutation profiling of hobnail variant of papillary thyroid carcinoma. Endocr Relat Cancer. 2017;24:107-117 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 4d
Zangari J, Ilie M, Rouaud F, Signetti L, Ohanna M, Didier R, et al. Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition. Nucleic Acids Res. 2017;45:4131-4141 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Runge T, Shaheen N, Djukic Z, Hallquist S, Orlando R. Cleavage of E-Cadherin Contributes to Defective Barrier Function in Neosquamous Epithelium. Dig Dis Sci. 2016;61:3169-3175 pubmed
  • 免疫印迹; 人类; 1:500; 图 s8
Chung I, Reichelt M, Shao L, Akita R, Koeppen H, Rangell L, et al. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016;7:12742 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:80; 图 3
Cardoso J, Mesquita M, Dias Pereira A, Bettencourt Dias M, Chaves P, Pereira Leal J. CYR61 and TAZ Upregulation and Focal Epithelial to Mesenchymal Transition May Be Early Predictors of Barrett's Esophagus Malignant Progression. PLoS ONE. 2016;11:e0161967 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 表 3
Liu S, Barry E, Baron J, Rutherford R, Seabrook M, Bostick R. Effects of supplemental calcium and vitamin D on the APC/β-catenin pathway in the normal colorectal mucosa of colorectal adenoma patients. Mol Carcinog. 2017;56:412-424 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2
Piton N, Wason J, Colasse É, Cornic M, Lemoine F, Le Pessot F, et al. Endoplasmic reticulum stress, unfolded protein response and development of colon adenocarcinoma. Virchows Arch. 2016;469:145-54 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:800; 表 1
Chung M, Lee J, Kim S, Suh Y, Choi H. Simple Prediction Model of Axillary Lymph Node Positivity After Analyzing Molecular and Clinical Factors in Early Breast Cancer. Medicine (Baltimore). 2016;95:e3689 pubmed 出版商
  • 免疫组化-石蜡切片; 犬; 1:100; 图 1a
Payan Carreira R, Pires M, Santos C, Holst B, Colaco J, Rodriguez Martinez H. Immunolocalization of E-cadherin and ?-catenin in the cyclic and early pregnant canine endometrium. Theriogenology. 2016;86:1092-1101 pubmed 出版商
  • 免疫组化; 人类
Song M, Park Y, Song H, Park S, Ahn J, Choi K, et al. Prognosis of Pregnancy-Associated Gastric Cancer: An Age-, Sex-, and Stage-Matched Case-Control Study. Gut Liver. 2016;10:731-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1c
Matsuda Y, Miura K, Yamane J, Shima H, Fujibuchi W, Ishida K, et al. SERPINI1 regulates epithelial-mesenchymal transition in an orthotopic implantation model of colorectal cancer. Cancer Sci. 2016;107:619-28 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3
Patkee W, Carr G, Baker E, Baines D, Garnett J. Metformin prevents the effects of Pseudomonas aeruginosa on airway epithelial tight junctions and restricts hyperglycaemia-induced bacterial growth. J Cell Mol Med. 2016;20:758-64 pubmed 出版商
  • 免疫组化; 人类; 1:2; 图 1
Terashita K, Chuma M, Hatanaka Y, Hatanaka K, Mitsuhashi T, Yokoo H, et al. ZEB1 expression is associated with prognosis of intrahepatic cholangiocarcinoma. J Clin Pathol. 2016;69:593-9 pubmed 出版商
  • 免疫细胞化学; 犬; 10 ug/ml; 图 4
Xu Y, Ma L, Norton M, Stuart C, Zhao Z, Toibero D, et al. Gestation age dependent transfer of human immunoglobulins across placenta in timed-pregnant guinea pigs. Placenta. 2015;36:1370-7 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
  • 染色质免疫沉淀 ; 小鼠
Gamba C, Rodrigues M, Gomes D, Estrela Lima A, Ferreira E, Cassali G. The Relationship Between E-Cadherin and its Transcriptional Repressors in Spontaneously Arising Canine Invasive Micropapillary Mammary Carcinoma. J Comp Pathol. 2015;153:256-65 pubmed 出版商
  • 免疫印迹; 人类
Mori S, Kodaira M, Ito A, Okazaki M, Kawaguchi N, Hamada Y, et al. Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells. PLoS ONE. 2015;10:e0137486 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 2
Baruch K, Rosenzweig N, Kertser A, Deczkowska A, Sharif A, Spinrad A, et al. Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology. Nat Commun. 2015;6:7967 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Ozgüven B, Tuncel D, Polat N, Sakiz D, Kabukcuoglu F, Köksal H, et al. Solid-pseudopapillary neoplasm of the pancreas: Clinicopathologic and immunohistochemical analysis of nine cases. Indian J Pathol Microbiol. 2015;58:292-5 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 2
Bartosch C, Mendes N, Rios E, Rodrigues M, Eloy C, Reis C, et al. Morphological features and mucin expression profile of breast carcinomas with signet-ring cell differentiation. Pathol Res Pract. 2015;211:588-95 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 7
Jackson B, Ivanova I, Dagnino L. An ELMO2-RhoG-ILK network modulates microtubule dynamics. Mol Biol Cell. 2015;26:2712-25 pubmed 出版商
  • 免疫组化-石蜡切片; 犬; 1:25
Mandara M, Reginato A, Foiani G, Baroni M, Poli F, Gasparinetti N, et al. Papillary meningioma in the dog: A clinicopathological case series study. Res Vet Sci. 2015;100:213-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Kim Y, Jin D, Lee B, Cho E, Han J, Shim Y, et al. RARβ2 hypermethylation is associated with poor recurrence-free survival in never-smokers with adenocarcinoma of the lung. Clin Epigenetics. 2015;7:32 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Fang J, Zhou H, Zhang C, Shang L, Zhang L, Xu J, et al. A novel vascular pattern promotes metastasis of hepatocellular carcinoma in an epithelial-mesenchymal transition-independent manner. Hepatology. 2015;62:452-65 pubmed 出版商
  • 免疫组化; 人类; 1:1200; 图 2
Kang Y, Cho C, Kwon S. Microcystic stromal tumor of the ovary with mutation in exon 3 of β-catenin: a case report. Int J Gynecol Pathol. 2015;34:121-5 pubmed 出版商
  • 免疫组化-石蜡切片; black ferret; 1:100; 表 3
Yui T, Ohmachi T, Matsuda K, Okamoto M, Taniyama H. Histochemical and immunohistochemical characterization of chordoma in ferrets. J Vet Med Sci. 2015;77:467-73 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Kang W, Lee J, Oh S, Lee S, Jung C. Stromal expression of miR-21 in T3-4a colorectal cancer is an independent predictor of early tumor relapse. BMC Gastroenterol. 2015;15:2 pubmed 出版商
  • 免疫组化; 人类
Figueira A, Gomes C, de Oliveira J, Vilhena H, Carvalheira J, de Matos A, et al. Aberrant P-cadherin expression is associated to aggressive feline mammary carcinomas. BMC Vet Res. 2014;10:270 pubmed 出版商
  • 免疫组化-冰冻切片; 人类
Raiko L, Leinonen P, Hägg P, Peltonen J, Oikarinen A, Peltonen S. Tight junctions in Hailey-Hailey and Darier's diseases. Dermatol Reports. 2009;1:e1 pubmed 出版商
  • 免疫印迹; 小鼠
Chang K, Zollinger D, Susuki K, Sherman D, Makara M, Brophy P, et al. Glial ankyrins facilitate paranodal axoglial junction assembly. Nat Neurosci. 2014;17:1673-81 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:800
Preda V, Larkin S, Karavitaki N, Ansorge O, Grossman A. The Wnt signalling cascade and the adherens junction complex in craniopharyngioma tumorigenesis. Endocr Pathol. 2015;26:1-8 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Altshuler A, Lamadrid I, Li D, Ma S, Kurre L, Schmid Schonbein G, et al. Transmural intestinal wall permeability in severe ischemia after enteral protease inhibition. PLoS ONE. 2014;9:e96655 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:25
Ohgami R, Chisholm K, Ma L, Arber D. E-cadherin is a specific marker for erythroid differentiation and has utility, in combination with CD117 and CD34, for enumerating myeloblasts in hematopoietic neoplasms. Am J Clin Pathol. 2014;141:656-64 pubmed 出版商
  • 免疫组化-石蜡切片; 犬; 1:50
Rodrigues M, Rema A, Gartner M, Laufer Amorim R. Role of adhesion molecules and proliferation hyperplasic, pre neoplastic and neoplastic lesions in canine prostate. Pak J Biol Sci. 2013;16:1324-9 pubmed
  • 免疫组化-石蜡切片; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类; 1:1000
Yu Y, Xiao C, Tan L, Wang Q, Li X, Feng Y. Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-? signalling. Br J Cancer. 2014;110:724-32 pubmed 出版商
  • 免疫组化; 人类; 1:400
Kim S, Kim M, Kim M, Kim S, Choi J, Yu E, et al. Pleomorphic solid pseudopapillary neoplasm of the pancreas: degenerative change rather than high-grade malignant potential. Hum Pathol. 2014;45:166-74 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Altshuler A, Richter M, Modestino A, Penn A, Heller M, Schmid Schonbein G. Removal of luminal content protects the small intestine during hemorrhagic shock but is not sufficient to prevent lung injury. Physiol Rep. 2013;1:e00109 pubmed 出版商
  • 免疫组化-石蜡切片; pigs ; 图 1
Basso K, Gomes F, Bracarense A. Deoxynivanelol and fumonisin, alone or in combination, induce changes on intestinal junction complexes and in E-cadherin expression. Toxins (Basel). 2013;5:2341-52 pubmed 出版商
  • 免疫细胞化学; Clostridioides difficile; 图 5
Kasendra M, Barrile R, Leuzzi R, Soriani M. Clostridium difficile toxins facilitate bacterial colonization by modulating the fence and gate function of colonic epithelium. J Infect Dis. 2014;209:1095-104 pubmed 出版商
  • 免疫细胞化学; 犬; 图 3
  • 免疫印迹; 犬; 图 7
Shiobara T, Usui T, Han J, Isoda H, Nagumo Y. The reversible increase in tight junction permeability induced by capsaicin is mediated via cofilin-actin cytoskeletal dynamics and decreased level of occludin. PLoS ONE. 2013;8:e79954 pubmed 出版商
  • 免疫组化; 人类
Yu L, Cheng H, Yang S. Clinicopathological and extensive immunohistochemical study of a type II pleuropulmonary blastoma. Fetal Pediatr Pathol. 2014;33:1-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Gu M, Choi J. Epithelial-mesenchymal transition phenotypes are associated with patient survival in intrahepatic cholangiocarcinoma. J Clin Pathol. 2014;67:229-34 pubmed 出版商
  • 免疫组化; 犬
Yasuno K, Nishiyama S, Kobayashi R, Yoshimura H, Takahashi K, Omachi T, et al. Proliferative lesions of intra-epidermal cytokeratin CAM5.2-positive cells in canine nipples. J Comp Pathol. 2014;150:18-26 pubmed 出版商
  • 免疫组化; 小鼠; 图 1
Karch I, Schipper E, Christgen H, Kreipe H, Lehmann U, Christgen M. Is upregulation of BCL2 a determinant of tumor development driven by inactivation of CDH1/E-cadherin?. PLoS ONE. 2013;8:e73062 pubmed 出版商
  • 免疫组化; pigs ; 图 2
Bracarense A, Yamasaki L, Silva E, Oliveira R, Alfieri A. Helicobacter spp. infection induces changes in epithelial proliferation and E-cadherin expression in the gastric mucosa of pigs. J Comp Pathol. 2013;149:402-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 1
Vlug E, van de Ven R, Vermeulen J, Bult P, van Diest P, Derksen P. Nuclear localization of the transcriptional coactivator YAP is associated with invasive lobular breast cancer. Cell Oncol (Dordr). 2013;36:375-84 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Chang C, Yang X, Pursell B, Mercurio A. Id2 complexes with the SNAG domain of Snai1 inhibiting Snai1-mediated repression of integrin ?4. Mol Cell Biol. 2013;33:3795-804 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Siljamäki E, Raiko L, Toriseva M, Nissinen L, Näreoja T, Peltonen J, et al. p38? mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes. Arch Dermatol Res. 2014;306:131-41 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 表 1
Bubis G, Hilly O, Bubis R, Halpern M, Schwartz A, Koren R, et al. A new Ki-67 / E-cadherin cocktail reduces inter-observer variation of the calculated proliferative index. Pathol Oncol Res. 2013;19:875-9 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 1
Schackmann R, Klarenbeek S, Vlug E, Stelloo S, van Amersfoort M, Tenhagen M, et al. Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling. Cancer Res. 2013;73:4937-49 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Pinho S, Figueiredo J, Cabral J, Carvalho S, Dourado J, Magalhaes A, et al. E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V. Biochim Biophys Acta. 2013;1830:2690-700 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 2
Vasconcelos Nóbrega C, Costa C, Vala H, Colaco A, Santos L, Lopes C, et al. E-cadherin and ?-catenin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in mice. Urol Int. 2013;91:462-6 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Griffin J, Wriston C, Peters M, Lehman J. Decreased expression of intercellular adhesion molecules in acantholytic squamous cell carcinoma compared with invasive well-differentiated squamous cell carcinoma of the skin. Am J Clin Pathol. 2013;139:442-7 pubmed 出版商
  • 免疫组化-石蜡切片; Japanese crane; 图 4
Sakaguchi K, Iima H, Matsuda K, Okamoto M, Hirayama K, Ikoma S, et al. Intestinal undifferentiated carcinoma in a red-crowned crane (Grus japonensis). J Vet Med Sci. 2013;75:827-30 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Taskin S, Dunder I, Erol E, Taşkin E, Kiremitci S, Oztuna D, et al. Roles of E-cadherin and cyclooxygenase enzymes in predicting different survival patterns of optimally cytoreduced serous ovarian cancer patients. Asian Pac J Cancer Prev. 2012;13:5715-9 pubmed
  • 免疫组化-冰冻切片; 人类; 1:200; 图 5
Angelucci C, Maulucci G, Lama G, Proietti G, Colabianchi A, Papi M, et al. Epithelial-stromal interactions in human breast cancer: effects on adhesion, plasma membrane fluidity and migration speed and directness. PLoS ONE. 2012;7:e50804 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Langer M, Duggan E, Booth J, Patel V, Zander R, Silasi Mansat R, et al. Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function. Infect Immun. 2012;80:4374-87 pubmed 出版商
  • 免疫组化; 人类; 1:50; 图 2
Ahearn T, Shaukat A, Flanders W, Rutherford R, Bostick R. A randomized clinical trial of the effects of supplemental calcium and vitamin D3 on the APC/?-catenin pathway in the normal mucosa of colorectal adenoma patients. Cancer Prev Res (Phila). 2012;5:1247-56 pubmed 出版商
  • 免疫组化; 小鼠; 1:150
Gil da Costa R, Oliveira P, Bastos M, Lopes C, Lopes C. Ptaquiloside-induced early-stage urothelial lesions show increased cell proliferation and intact ?-catenin and E-cadherin expression. Environ Toxicol. 2014;29:763-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400; 图 1
Tsang J, Mendoza P, Putti T, Karim R, Scolyer R, Lee C, et al. E-cadherin expression in the epithelial components of mammary phyllodes tumors. Hum Pathol. 2012;43:2117-23 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 2
Vermeulen J, van de Ven R, Ercan C, van der Groep P, van der Wall E, Bult P, et al. Nuclear Kaiso expression is associated with high grade and triple-negative invasive breast cancer. PLoS ONE. 2012;7:e37864 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Tobin N, Lundgren K, Conway C, Anagnostaki L, Costello S, Landberg G. Automated image analysis of cyclin D1 protein expression in invasive lobular breast carcinoma provides independent prognostic information. Hum Pathol. 2012;43:2053-61 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6
Iacopino F, Angelucci C, Sica G. Interactions between normal human fibroblasts and human prostate cancer cells in a co-culture system. Anticancer Res. 2012;32:1579-88 pubmed
  • 免疫组化-石蜡切片; 人类; 1:50; 表 2
Ahearn T, Shaukat A, Flanders W, Seabrook M, Bostick R. Markers of the APC/?-catenin signaling pathway as potential treatable, preneoplastic biomarkers of risk for colorectal neoplasms. Cancer Epidemiol Biomarkers Prev. 2012;21:969-79 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 1
Vincent Salomon A, Hajage D, Rouquette A, Cédenot A, Gruel N, Alran S, et al. High Ki67 expression is a risk marker of invasive relapse for classical lobular carcinoma in situ patients. Breast. 2012;21:380-3 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 3
Stoyianni A, Goussia A, Pentheroudakis G, Siozopoulou V, Ioachim E, Krikelis D, et al. Immunohistochemical study of the epithelial-mesenchymal transition phenotype in cancer of unknown primary: incidence, correlations and prognostic utility. Anticancer Res. 2012;32:1273-81 pubmed
  • 免疫组化-石蜡切片; 人类; 1:25; 图 1
Chang D, Pai R, Rybicki L, DiMaio M, Limaye M, Jayachandran P, et al. Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: an adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features. Mod Pathol. 2012;25:1128-39 pubmed 出版商
  • 免疫组化; 人类; 图 3
Lisch W, Bron A, Munier F, Schorderet D, Tiab L, Lange C, et al. Franceschetti hereditary recurrent corneal erosion. Am J Ophthalmol. 2012;153:1073-81.e4 pubmed 出版商
  • 免疫细胞化学; 犬; 图 1
Dukes J, Whitley P, Chalmers A. The PIKfyve inhibitor YM201636 blocks the continuous recycling of the tight junction proteins claudin-1 and claudin-2 in MDCK cells. PLoS ONE. 2012;7:e28659 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Palka Bayard de Volo C, Alfonsi M, Gatta V, Novelli A, Bernardini L, Fantasia D, et al. 16q22.1 microdeletion detected by array-CGH in a family with mental retardation and lobular breast cancer. Gene. 2012;498:328-31 pubmed 出版商
  • 免疫组化; 人类; 图 2
Zhang J, Liang Z, Gao J, Luo Y, Liu T. Pulmonary adenocarcinoma with a micropapillary pattern: a clinicopathological, immunophenotypic and molecular analysis. Histopathology. 2011;59:1204-14 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Zhi W, Xue B, Wang L, Xiao N, He Q, Wang Y, et al. The MLH1 2101C>A (Q701K) variant increases the risk of gastric cancer in Chinese males. BMC Gastroenterol. 2011;11:133 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 5
Schneider D, Wu M, Le T, Cho S, Brenner M, Blackburn M, et al. Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-? production and epithelial to mesenchymal transition. FASEB J. 2012;26:503-12 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Giricz O, Reynolds P, Ramnauth A, Liu C, Wang T, Stead L, et al. Hsa-miR-375 is differentially expressed during breast lobular neoplasia and promotes loss of mammary acinar polarity. J Pathol. 2012;226:108-19 pubmed 出版商
  • 免疫组化-石蜡切片; pigs ; 1:50; 图 5
Bracarense A, Lucioli J, Grenier B, Drociunas Pacheco G, Moll W, Schatzmayr G, et al. Chronic ingestion of deoxynivalenol and fumonisin, alone or in interaction, induces morphological and immunological changes in the intestine of piglets. Br J Nutr. 2012;107:1776-86 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 7
  • 免疫组化-石蜡切片; 人类; 1:500; 图 7
Sin S, Bonin F, Petit V, Meseure D, Lallemand F, Bieche I, et al. Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis. J Natl Cancer Inst. 2011;103:1323-37 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Kobayashi Y, Shimizu T, Naoe H, Ueki A, Ishizawa J, Chiyoda T, et al. Establishment of a choriocarcinoma model from immortalized normal extravillous trophoblast cells transduced with HRASV12. Am J Pathol. 2011;179:1471-82 pubmed 出版商
  • 免疫细胞化学; 犬; 1:25; 图 1
Dukes J, Fish L, Richardson J, Blaikley E, Burns S, Caunt C, et al. Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells. Mol Biol Cell. 2011;22:3192-205 pubmed 出版商
  • 免疫组化; 小鼠; 图 2
Essbauer S, Krautkrämer E, Herzog S, Pfeffer M. A new permanent cell line derived from the bank vole (Myodes glareolus) as cell culture model for zoonotic viruses. Virol J. 2011;8:339 pubmed 出版商
  • 免疫组化; 小鼠; 图 3
Russell S, Lechner M, Gong L, Megiel C, Liebertz D, Masood R, et al. USC-HN2, a new model cell line for recurrent oral cavity squamous cell carcinoma with immunosuppressive characteristics. Oral Oncol. 2011;47:810-7 pubmed 出版商
  • 免疫组化; 小鼠; 图 s3
Goel H, Bae D, Pursell B, Gouvin L, Lu S, Mercurio A. Neuropilin-2 promotes branching morphogenesis in the mouse mammary gland. Development. 2011;138:2969-76 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2
Betge J, Pollheimer M, Schlemmer A, Hoefler G, Langner C. Gastric cancer and concomitant renal cancer: a systematic immunohistochemical and molecular analysis. Oncol Rep. 2011;26:567-75 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Ding T, Xu J, Zhang Y, Guo R, Wu W, Zhang S, et al. Endothelium-coated tumor clusters are associated with poor prognosis and micrometastasis of hepatocellular carcinoma after resection. Cancer. 2011;117:4878-89 pubmed 出版商
  • 免疫组化; 人类; 图 4
Jovov B, Que J, Tobey N, Djukic Z, Hogan B, Orlando R. Role of E-cadherin in the pathogenesis of gastroesophageal reflux disease. Am J Gastroenterol. 2011;106:1039-47 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Ferreira E, Gobbi H, Saraiva B, Cassali G. Histological and immunohistochemical identification of atypical ductal mammary hyperplasia as a preneoplastic marker in dogs. Vet Pathol. 2012;49:322-9 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:120; 图 7
Chen M, Peyrin Biroulet L, George A, Coste F, Bressenot A, Bossenmeyer Pourié C, et al. Methyl deficient diet aggravates experimental colitis in rats. J Cell Mol Med. 2011;15:2486-97 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Lewis Tuffin L, Rodriguez F, Giannini C, Scheithauer B, Necela B, Sarkaria J, et al. Misregulated E-cadherin expression associated with an aggressive brain tumor phenotype. PLoS ONE. 2010;5:e13665 pubmed 出版商
  • 免疫组化; 人类; 1:50; 图 6
da Cunha C, Oliveira C, Wen X, Gomes B, Sousa S, Suriano G, et al. De novo expression of CD44 variants in sporadic and hereditary gastric cancer. Lab Invest. 2010;90:1604-14 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Yong Jiang -, Huawei Liu -, Hu Long -, Yingying Yang -, Dianying Liao -, Xiuhui Zhang -. Goblet cell carcinoid of the appendix: a clinicopathological and immunohistochemical study of 26 cases from southwest china. Int J Surg Pathol. 2010;18:488-92 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 2
Gwin K, Buell Gutbrod R, Tretiakova M, Montag A. Epithelial-to-mesenchymal transition in metaplastic breast carcinomas with chondroid differentiation: expression of the E-cadherin repressor Snail. Appl Immunohistochem Mol Morphol. 2010;18:526-31 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 2
Koensgen D, Freitag C, Klaman I, Dahl E, Mustea A, Chekerov R, et al. Expression and localization of e-cadherin in epithelial ovarian cancer. Anticancer Res. 2010;30:2525-30 pubmed
  • 免疫细胞化学; 人类; 图 3
  • 免疫印迹; 人类; 图 2
Rozich R, Mills D, Brilliant K, Callanan H, Yang D, Tantravahi U, et al. Accumulation of neoplastic traits prior to spontaneous in vitro transformation of rat cholangiocytes determines susceptibility to activated ErbB-2/Neu. Exp Mol Pathol. 2010;89:248-59 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:800; 图 3
Kim H, Kim G, Kim Y, Park Y, Song J, Lim S. Stromal CD10 expression and relationship to the E-cadherin/beta-catenin complex in breast carcinoma. Histopathology. 2010;56:708-19 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50; 图 1
Alarcon V. Cell polarity regulator PARD6B is essential for trophectoderm formation in the preimplantation mouse embryo. Biol Reprod. 2010;83:347-58 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 3
Sato Y, Harada K, Itatsu K, Ikeda H, Kakuda Y, Shimomura S, et al. Epithelial-mesenchymal transition induced by transforming growth factor-{beta}1/Snail activation aggravates invasive growth of cholangiocarcinoma. Am J Pathol. 2010;177:141-52 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 4
Qi H, Zheng X, Yuan X, Pflugfelder S, Li D. Potential localization of putative stem/progenitor cells in human bulbar conjunctival epithelium. J Cell Physiol. 2010;225:180-5 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:40; 图 1
Rosa M, Mohammadi A, Masood S. Lobular neoplasia displaying central necrosis: a potential diagnostic pitfall. Pathol Res Pract. 2010;206:544-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 1
Giusiano S, Secq V, Carcopino X, Carpentier S, Andrac L, Lavaut M, et al. Immunohistochemical profiling of node negative breast carcinomas allows prediction of metastatic risk. Int J Oncol. 2010;36:889-98 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100; 图 4
Ferreira E, Gobbi H, Saraiva B, Cassali G. Columnar cell lesions of the canine mammary gland: pathological features and immunophenotypic analysis. BMC Cancer. 2010;10:61 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Suzuki H, Komatsu A, Fujioka Y, Yamashiro K, Takeda H, Hamada T. Angiosarcoma-like metastatic carcinoma of the liver. Pathol Res Pract. 2010;206:484-8 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 3
Asioli S, Erickson L, Sebo T, Zhang J, Jin L, Thompson G, et al. Papillary thyroid carcinoma with prominent hobnail features: a new aggressive variant of moderately differentiated papillary carcinoma. A clinicopathologic, immunohistochemical, and molecular study of eight cases. Am J Surg Pathol. 2010;34:44-52 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 6
  • 免疫印迹; 人类; 1:500; 图 3
Lundgren K, Nordenskjold B, Landberg G. Hypoxia, Snail and incomplete epithelial-mesenchymal transition in breast cancer. Br J Cancer. 2009;101:1769-81 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
Zhang D, Lafortune T, Krishnamurthy S, Esteva F, Cristofanilli M, Liu P, et al. Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer. Clin Cancer Res. 2009;15:6639-48 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Graesslin O, Antoine M, Chopier J, Seror J, Flahault A, Callard P, et al. Histology after lumpectomy in women with epithelial atypia on stereotactic vacuum-assisted breast biopsy. Eur J Surg Oncol. 2010;36:170-5 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Polton G, Brearley M, Green L, Scase T. Expression of E-cadherin in canine anal sac gland carcinoma and its association with survival. Vet Comp Oncol. 2007;5:232-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Zou J, Yang H, Chen F, Zhao H, Lin P, Zhang J, et al. Prognostic significance of fascin-1 and E-cadherin expression in laryngeal squamous cell carcinoma. Eur J Cancer Prev. 2010;19:11-7 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 5
Weiswald L, Richon S, Validire P, Briffod M, Lai Kuen R, Cordelières F, et al. Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness. Br J Cancer. 2009;101:473-82 pubmed 出版商
  • 免疫组化; 犬; 图 1
Pires I, Queiroga F, Alves A, Silva F, Lopes C. Decrease of E-cadherin expression in canine cutaneous histiocytoma appears to be related to its spontaneous regression. Anticancer Res. 2009;29:2713-7 pubmed
  • 免疫组化; 人类; 1:50; 图 1
Zhu Y, Ye D, Yao X, Zhang S, Dai B, Zhang H, et al. Clinicopathological characteristics, management and outcome of metastatic penoscrotal extramammary Paget's disease. Br J Dermatol. 2009;161:577-82 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1
Ohashi M, Kusumi T, Sato F, Kudo Y, Jin H, Akasaka H, et al. Expression of syndecan-1 and E-cadherin is inversely correlated with poor patient's prognosis and recurrent status of extrahepatic bile duct carcinoma. Biomed Res. 2009;30:79-86 pubmed
  • 免疫细胞化学; 人类; 1 ug/ml; 图 1
Elwi A, Damaraju V, Kuzma M, Mowles D, Baldwin S, Young J, et al. Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3. Am J Physiol Renal Physiol. 2009;296:F1439-51 pubmed 出版商
  • 免疫组化; 人类
Charpin C, Giusiano S, Secq V, Carpentier S, Andrac L, Lavaut M, et al. Quantitative immunocytochemical profile to predict early outcome of disease in triple-negative breast carcinomas. Int J Oncol. 2009;34:983-93 pubmed
  • 免疫组化; 人类; 表 4
Oliveira C, Sousa S, Pinheiro H, Karam R, Bordeira Carriço R, Senz J, et al. Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression. Gastroenterology. 2009;136:2137-48 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1b
Sarrio D, Palacios J, Hergueta Redondo M, Gomez Lopez G, Cano A, Moreno Bueno G. Functional characterization of E- and P-cadherin in invasive breast cancer cells. BMC Cancer. 2009;9:74 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 表 2
Gil da Costa R, Santos M, Amorim I, Lopes C, Pereira P, Faustino A. An immunohistochemical study of feline endometrial adenocarcinoma. J Comp Pathol. 2009;140:254-9 pubmed 出版商
  • 免疫印迹; 犬; 图 1
  • 免疫印迹; 人类; 图 1
Pinho S, Osorio H, Nita Lazar M, Gomes J, Lopes C, Gartner F, et al. Role of E-cadherin N-glycosylation profile in a mammary tumor model. Biochem Biophys Res Commun. 2009;379:1091-6 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:100; 图 1
Alanne M, Pummi K, Heape A, Grenman R, Peltonen J, Peltonen S. Tight junction proteins in human Schwann cell autotypic junctions. J Histochem Cytochem. 2009;57:523-9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 表 1
Charpin C, Secq V, Giusiano S, Carpentier S, Andrac L, Lavaut M, et al. A signature predictive of disease outcome in breast carcinomas, identified by quantitative immunocytochemical assays. Int J Cancer. 2009;124:2124-34 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50
Patriarca C, Colombo P, Pio Taronna A, Wesseling J, Franchi G, Guddo F, et al. Cell discohesion and multifocality of carcinoma in situ of the bladder: new insight from the adhesion molecule profile (e-cadherin, Ep-CAM, and MUC1). Int J Surg Pathol. 2009;17:99-106 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:2000
Rodriguez F, Scheithauer B, Giannini C, Bryant S, Jenkins R. Epithelial and pseudoepithelial differentiation in glioblastoma and gliosarcoma: a comparative morphologic and molecular genetic study. Cancer. 2008;113:2779-89 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 2.5 ug/ml; 图 2
Saha B, Kaur P, Tsao Wei D, Naritoku W, Groshen S, Datar R, et al. Unmethylated E-cadherin gene expression is significantly associated with metastatic human prostate cancer cells in bone. Prostate. 2008;68:1681-8 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
Mosnier J, Kandel C, Cazals Hatem D, Bou Hanna C, Gournay J, Jarry A, et al. N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas. Mod Pathol. 2009;22:182-90 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 表 2
Simpson P, Reis Filho J, Lambros M, Jones C, Steele D, Mackay A, et al. Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. J Pathol. 2008;215:231-44 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50
Laser J, Cangiarella J, Singh B, Melamed J, Chiriboga L, Yee H, et al. Invasive lobular carcinoma of the breast: role of endothelial lymphatic marker D2-40. Ann Clin Lab Sci. 2008;38:99-104 pubmed
  • 免疫组化-石蜡切片; 人类; 1:40
Fondrevelle M, Kantelip B, Reiter R, Chopin D, Thiery J, Monnien F, et al. The expression of Twist has an impact on survival in human bladder cancer and is influenced by the smoking status. Urol Oncol. 2009;27:268-76 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 2
Fevre Montange M, Grand S, Champier J, Hoffmann D, Pasquier B, Jouvet A. Bcl-2 expression in a papillary tumor of the pineal region. Neuropathology. 2008;28:660-3 pubmed 出版商
  • 免疫组化; 人类; 1:100; 表 2
MacGrogan G, Arnould L, de Mascarel I, Vincent Salomon A, Penault Llorca F, Lacroix Triki M, et al. Impact of immunohistochemical markers, CK5/6 and E-cadherin on diagnostic agreement in non-invasive proliferative breast lesions. Histopathology. 2008;52:689-97 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Boone J, van Hillegersberg R, van Diest P, Offerhaus G, Rinkes I, Kate F. Validation of tissue microarray technology in squamous cell carcinoma of the esophagus. Virchows Arch. 2008;452:507-14 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 5
Sawada K, Mitra A, Radjabi A, Bhaskar V, Kistner E, Tretiakova M, et al. Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target. Cancer Res. 2008;68:2329-39 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 4
Liu X, Pan M, Lu Z, Wu B, Rao Q, Zhou Z, et al. Expression of Wnt-5a and its clinicopathological significance in hepatocellular carcinoma. Dig Liver Dis. 2008;40:560-7 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:100
Shi S, Liu C, Pootrakul L, Tang L, Young A, Chen R, et al. Evaluation of the value of frozen tissue section used as "gold standard" for immunohistochemistry. Am J Clin Pathol. 2008;129:358-66 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Wu J, Yan H, Chen W, Chen W, Wang C, Chi Y, et al. JNK signaling pathway is required for bFGF-mediated surface cadherin downregulation on HUVEC. Exp Cell Res. 2008;314:421-9 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 图 3
Sato Y, Harada K, Ozaki S, Furubo S, Kizawa K, Sanzen T, et al. Cholangiocytes with mesenchymal features contribute to progressive hepatic fibrosis of the polycystic kidney rat. Am J Pathol. 2007;171:1859-71 pubmed
  • 免疫组化-石蜡切片; 人类; 图 1a
Saha B, Arase A, Imam S, Tsao Wei D, Naritoku W, Groshen S, et al. Overexpression of E-cadherin and beta-catenin proteins in metastatic prostate cancer cells in bone. Prostate. 2008;68:78-84 pubmed
  • 免疫组化-石蜡切片; 人类; 1:200
Itatsu K, Zen Y, Ohira S, Ishikawa A, Sato Y, Harada K, et al. Immunohistochemical analysis of the progression of flat and papillary preneoplastic lesions in intrahepatic cholangiocarcinogenesis in hepatolithiasis. Liver Int. 2007;27:1174-84 pubmed
  • 免疫组化-石蜡切片; 人类
Karacali B, Vamvakidou A, Tozeren A. Automated recognition of cell phenotypes in histology images based on membrane- and nuclei-targeting biomarkers. BMC Med Imaging. 2007;7:7 pubmed
  • 免疫印迹; 人类; 1:1500; 图 3
Angelucci C, Iacopino F, Ferracuti S, Urbano R, Sica G. Recombinant human IFN-beta affects androgen receptor level, neuroendocrine differentiation, cell adhesion, and motility in prostate cancer cells. J Interferon Cytokine Res. 2007;27:643-52 pubmed
  • 免疫组化; 人类; 1:2000; 表 3
Goldstein N, Decker D, Severson D, Schell S, Vicini F, Margolis J, et al. Molecular classification system identifies invasive breast carcinoma patients who are most likely and those who are least likely to achieve a complete pathologic response after neoadjuvant chemotherapy. Cancer. 2007;110:1687-96 pubmed
  • 免疫组化; 犬; 1:100
Gama A, Paredes J, Gartner F, Alves A, Schmitt F. Expression of E-cadherin, P-cadherin and beta-catenin in canine malignant mammary tumours in relation to clinicopathological parameters, proliferation and survival. Vet J. 2008;177:45-53 pubmed
  • 免疫组化; 犬; 图 3
Pinho S, Matos A, Lopes C, Marcos N, Carvalheira J, Reis C, et al. Sialyl Lewis x expression in canine malignant mammary tumours: correlation with clinicopathological features and E-Cadherin expression. BMC Cancer. 2007;7:124 pubmed
  • 免疫组化; 人类
Leibl S, Regitnig P, Moinfar F. Flat epithelial atypia (DIN 1a, atypical columnar change): an underdiagnosed entity very frequently coexisting with lobular neoplasia. Histopathology. 2007;50:859-65 pubmed
  • 免疫组化-石蜡切片; 人类; 1:320
Norton J, Ham C, Van Dam J, Jeffrey R, Longacre T, Huntsman D, et al. CDH1 truncating mutations in the E-cadherin gene: an indication for total gastrectomy to treat hereditary diffuse gastric cancer. Ann Surg. 2007;245:873-9 pubmed
  • 免疫组化-石蜡切片; 人类; 图 1
De Matos A, Lopes C, Faustino A, Carvalheira J, Rutteman G, Gärtner M. E-cadherin, beta-catenin, invasion and lymph node metastases in canine malignant mammary tumours. APMIS. 2007;115:327-34 pubmed
  • 免疫组化-石蜡切片; 人类; 1:50
Zhu Y, Zhou X, Yao X, Dai B, Ye D. The prognostic significance of p53, Ki-67, epithelial cadherin and matrix metalloproteinase-9 in penile squamous cell carcinoma treated with surgery. BJU Int. 2007;100:204-8 pubmed
  • 免疫细胞化学; 人类; 1:200; 图 2D
  • 免疫印迹; 人类; 1:1000; 图 3C
Stucke V, Timmerman E, Vandekerckhove J, Gevaert K, Hall A. The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation. Mol Biol Cell. 2007;18:1744-55 pubmed
  • 免疫细胞化学; 人类; 1:300; 图 5
Symowicz J, Adley B, Gleason K, Johnson J, Ghosh S, Fishman D, et al. Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cells. Cancer Res. 2007;67:2030-9 pubmed
  • 免疫印迹; 人类; 图 3
Endemann M, Bergmeister H, Bidmon B, Boehm M, Csaicsich D, Malaga Dieguez L, et al. Evidence for HSP-mediated cytoskeletal stabilization in mesothelial cells during acute experimental peritoneal dialysis. Am J Physiol Renal Physiol. 2007;292:F47-56 pubmed
  • 免疫组化; 人类; 1:200; 表 1
Reis Filho J, Simpson P, Turner N, Lambros M, Jones C, Mackay A, et al. FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clin Cancer Res. 2006;12:6652-62 pubmed
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1
Bobrich E, Braumann C, Opitz I, Menenakos C, Kristiansen G, Jacobi C. Influence of intraperitoneal application of taurolidine/heparin on expression of adhesion molecules and colon cancer in rats undergoing laparoscopy. J Surg Res. 2007;137:75-82 pubmed
  • 免疫组化-冰冻切片; 人类
Steenvoorden M, Tolboom T, van der Pluijm G, Lowik C, Visser C, Degroot J, et al. Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics. Arthritis Res Ther. 2006;8:R165 pubmed
  • 免疫细胞化学; 犬; 图 S1
Martín Villar E, Megias D, Castel S, Yurrita M, Vilaró S, Quintanilla M. Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition. J Cell Sci. 2006;119:4541-53 pubmed
  • 免疫组化; 犬; 1:200; 图 5
Moreno Bueno G, Cubillo E, Sarrio D, Peinado H, Rodriguez Pinilla S, Villa S, et al. Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. Cancer Res. 2006;66:9543-56 pubmed
  • 免疫组化-石蜡切片; 人类; 图 2
  • 免疫细胞化学; 人类; 图 3
  • 免疫印迹; 人类; 图 3
Lee T, Poon R, Yuen A, Ling M, Kwok W, Wang X, et al. Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition. Clin Cancer Res. 2006;12:5369-76 pubmed
  • 免疫组化-石蜡切片; 人类; 1:200
Baker K, Chong G, Foulkes W, Jass J. Transforming growth factor-beta pathway disruption and infiltration of colorectal cancers by intraepithelial lymphocytes. Histopathology. 2006;49:371-80 pubmed
  • 免疫组化-石蜡切片; 猕猴
Wood C, Usborne A, Starost M, Tarara R, Hill L, Wilkinson L, et al. Hyperplastic and neoplastic lesions of the mammary gland in macaques. Vet Pathol. 2006;43:471-83 pubmed
  • 免疫组化-石蜡切片; 人类
Guarino M, Ballabio G, Rubino B, Nebuloni M, Tosoni A. Soft tissue sacrococcygeal chordoma with intracytoplasmic filamentous inclusions. Pathol Res Pract. 2005;201:699-704 pubmed
  • 免疫印迹; 人类; 1:500; 图 3
Berglund P, Stighall M, Jirstrom K, Borgquist S, Sjölander A, Hedenfalk I, et al. Cyclin E overexpression obstructs infiltrative behavior in breast cancer: a novel role reflected in the growth pattern of medullary breast cancers. Cancer Res. 2005;65:9727-34 pubmed
  • 免疫组化-石蜡切片; 人类; 1:400; 表 2
Sakamoto K, Watanabe M, de la Cruz C, Honda H, Ise H, Mitsui K, et al. Primary invasive micropapillary carcinoma of the colon. Histopathology. 2005;47:479-84 pubmed
  • 免疫细胞化学; 人类; 图 5
Veveris Lowe T, Lawrence M, Collard R, Bui L, Herington A, Nicol D, et al. Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells. Endocr Relat Cancer. 2005;12:631-43 pubmed
  • 免疫组化-石蜡切片; 人类; 1:400; 表 2
Pelosi G, Scarpa A, Veronesi G, Spaggiari L, Del Curto B, Moore P, et al. A subset of high-grade pulmonary neuroendocrine carcinomas shows up-regulation of matrix metalloproteinase-7 associated with nuclear beta-catenin immunoreactivity, independent of EGFR and HER-2 gene amplification or expression. Virchows Arch. 2005;447:969-77 pubmed
  • 免疫印迹; 人类
Shiraishi K, Tsuzaka K, Yoshimoto K, Kumazawa C, Nozaki K, Abe T, et al. Critical role of the fifth domain of E-cadherin for heterophilic adhesion with alpha E beta 7, but not for homophilic adhesion. J Immunol. 2005;175:1014-21 pubmed
  • 免疫组化-石蜡切片; 人类; 1:40
Kwon G, Yoo B, Koh K, Cho J, Park W, Park C. Promoter methylation of E-cadherin in hepatocellular carcinomas and dysplastic nodules. J Korean Med Sci. 2005;20:242-7 pubmed
  • 免疫组化-石蜡切片; 人类; 1:400; 表 2
Pelosi G, Scarpa A, Puppa G, Veronesi G, Spaggiari L, Pasini F, et al. Alteration of the E-cadherin/beta-catenin cell adhesion system is common in pulmonary neuroendocrine tumors and is an independent predictor of lymph node metastasis in atypical carcinoids. Cancer. 2005;103:1154-64 pubmed
  • 免疫组化-石蜡切片; 人类; 表 1
Langner C, Ratschek M, Rehak P, Tsybrovskyy O, Zigeuner R. The pT1a and pT1b category subdivision in renal cell carcinoma: is it reflected by differences in tumour biology?. BJU Int. 2005;95:310-4 pubmed
  • 免疫组化-石蜡切片; 人类; 1:40
Wheeler D, Tai L, Bratthauer G, Waldner D, Tavassoli F. Tubulolobular carcinoma of the breast: an analysis of 27 cases of a tumor with a hybrid morphology and immunoprofile. Am J Surg Pathol. 2004;28:1587-93 pubmed
  • 免疫组化-石蜡切片; 人类; 1:500
  • 免疫细胞化学; 人类; 1:100
Martín Villar E, Scholl F, Gamallo C, Yurrita M, Muñoz Guerra M, Cruces J, et al. Characterization of human PA2.26 antigen (T1alpha-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas. Int J Cancer. 2005;113:899-910 pubmed
  • 免疫细胞化学; 人类; 图 4
Zeng R, Li X, Gorodeski G. Estrogen abrogates transcervical tight junctional resistance by acceleration of occludin modulation. J Clin Endocrinol Metab. 2004;89:5145-55 pubmed
  • 免疫组化-石蜡切片; 人类
Lyakhovitsky A, Barzilai A, Fogel M, Trau H, Huszar M. Expression of e-cadherin and beta-catenin in cutaneous squamous cell carcinoma and its precursors. Am J Dermatopathol. 2004;26:372-8 pubmed
  • 免疫组化; 人类; 1:50; 图 3
Sastre Garau X, Genin P, Rousseau A, Al Ghuzlan A, Nicolas A, Freneaux P, et al. Increased cell size and Akt activation in HER-2/neu-overexpressing invasive ductal carcinoma of the breast. Histopathology. 2004;45:142-7 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100
Aubert S, Duchene F, Augusto D, Llinares K, Lemaitre L, Gosselin B, et al. Low-grade tubular myxoid renal tumors: a clinicopathological study of 3 cases. Int J Surg Pathol. 2004;12:179-83 pubmed
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1
  • 免疫印迹; 人类; 1:1000; 图 4
Sarrio D, Perez Mies B, Hardisson D, Moreno Bueno G, Suárez A, Cano A, et al. Cytoplasmic localization of p120ctn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions. Oncogene. 2004;23:3272-83 pubmed
  • 免疫组化; 人类; 1:50; 图 1
Slobodov G, Feloney M, Gran C, Kyker K, Hurst R, Culkin D. Abnormal expression of molecular markers for bladder impermeability and differentiation in the urothelium of patients with interstitial cystitis. J Urol. 2004;171:1554-8 pubmed
  • 免疫组化-石蜡切片; 人类; 图 1
Nishioka H, Haraoka J, Akada K. Fibrous bodies are associated with lower GH production and decreased expression of E-cadherin in GH-producing pituitary adenomas. Clin Endocrinol (Oxf). 2003;59:768-72 pubmed
  • 免疫组化-石蜡切片; 人类; 1:400
De La Cruz C, Moriya T, Endoh M, Watanabe M, Takeyama J, Yang M, et al. Invasive micropapillary carcinoma of the breast: clinicopathological and immunohistochemical study. Pathol Int. 2004;54:90-6 pubmed
  • 免疫组化-石蜡切片; 人类; 图 4
Alami J, Williams B, Yeger H. Derivation and characterization of a Wilms' tumour cell line, WiT 49. Int J Cancer. 2003;107:365-74 pubmed
  • 免疫组化-石蜡切片; 人类; 1:50
  • 免疫印迹; 人类; 1:50
Alami J, Williams B, Yeger H. Differential expression of E-cadherin and beta catenin in primary and metastatic Wilms's tumours. Mol Pathol. 2003;56:218-25 pubmed
  • 免疫组化-石蜡切片; 人类
Fidder H, Barshack I, Chen Shtoyerman R, Onaca N, Goldberg I, Rath P, et al. Immunohistochemical analyses of colon cancer in I1307K APC mutation carriers compared with noncarriers. Dig Dis Sci. 2003;48:1102-5 pubmed
  • 免疫组化-石蜡切片; 人类; 图 1
Sarrio D, Moreno Bueno G, Hardisson D, Sánchez Estevez C, Guo M, Herman J, et al. Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability. Int J Cancer. 2003;106:208-15 pubmed
  • 免疫细胞化学; 小鼠; 1:100
Luo Y, Radice G. Cadherin-mediated adhesion is essential for myofibril continuity across the plasma membrane but not for assembly of the contractile apparatus. J Cell Sci. 2003;116:1471-9 pubmed
  • 免疫组化; 人类; 表 2
Bratthauer G, Moinfar F, Stamatakos M, Mezzetti T, Shekitka K, Man Y, et al. Combined E-cadherin and high molecular weight cytokeratin immunoprofile differentiates lobular, ductal, and hybrid mammary intraepithelial neoplasias. Hum Pathol. 2002;33:620-7 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 2
  • 免疫印迹; 小鼠; 1:1000; 图 1
Ferreira Cornwell M, Luo Y, Narula N, Lenox J, Lieberman M, Radice G. Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart. J Cell Sci. 2002;115:1623-34 pubmed
  • 免疫组化; 人类
Mert G. National action plan on Breast Cancer Workshop on Multicultural Aspects of Breast Cancer Etiology: recommendations of the workshop. Cancer. 2002;94:2113 pubmed
  • 免疫组化-石蜡切片; 人类; 1:200
Laskin W, Miettinen M. Epithelial-type and neural-type cadherin expression in malignant noncarcinomatous neoplasms with epithelioid features that involve the soft tissues. Arch Pathol Lab Med. 2002;126:425-31 pubmed
  • 免疫组化-石蜡切片; 人类; 1:50; 图 4
Goldstein N, Kestin L, Vicini F. Clinicopathologic implications of E-cadherin reactivity in patients with lobular carcinoma in situ of the breast. Cancer. 2001;92:738-47 pubmed
  • 免疫组化-石蜡切片; 人类
Barshack I, Goldberg I, Chowers Y, Weiss B, Horowitz A, Kopolovic J. Immunohistochemical analysis of candidate gene product expression in the duodenal epithelium of children with coeliac sprue. J Clin Pathol. 2001;54:684-8 pubmed
Guindolet D, Crouzet E, He Z, Herbepin P, Perrache C, Garcin T, et al. Epithelial Regeneration in Human Corneas Preserved in an Active Storage Machine. Transl Vis Sci Technol. 2021;10:31 pubmed 出版商
Wang Z, Shang J, Li Z, Li H, Zhang C, He K, et al. PIK3CA Is Regulated by CUX1, Promotes Cell Growth and Metastasis in Bladder Cancer via Activating Epithelial-Mesenchymal Transition. Front Oncol. 2020;10:536072 pubmed 出版商
Brocato R, Principe L, Kim R, Zeng X, Williams J, Liu Y, et al. Disruption of Adaptive Immunity Enhances Disease in SARS-CoV-2-Infected Syrian Hamsters. J Virol. 2020;94: pubmed 出版商
Golden J, Cline C, Zeng X, Garrison A, Carey B, Mucker E, et al. Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease. JCI Insight. 2020;5: pubmed 出版商
Shi X, Kaller M, Rokavec M, Kirchner T, Horst D, Hermeking H. Characterization of a p53/miR-34a/CSF1R/STAT3 Feedback Loop in Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2020;10:391-418 pubmed 出版商
Rokavec M, Bouznad N, Hermeking H. Paracrine Induction of Epithelial-Mesenchymal Transition Between Colorectal Cancer Cells and its Suppression by a p53/miR-192/215/NID1 Axis. Cell Mol Gastroenterol Hepatol. 2019;7:783-802 pubmed 出版商
Mylavarapu S, Kumar H, Kumari S, Sravanthi L, Jain M, Basu A, et al. Activation of Epithelial-Mesenchymal Transition and Altered β-Catenin Signaling in a Novel Indian Colorectal Carcinoma Cell Line. Front Oncol. 2019;9:54 pubmed 出版商
He S, Carman C, Lee J, Lan B, Koehler S, Atia L, et al. The tumor suppressor p53 can promote collective cellular migration. PLoS ONE. 2019;14:e0202065 pubmed 出版商
Blanchard A, Ma X, Wang N, Hombach Klonisch S, Penner C, Ozturk A, et al. Claudin 1 Is Highly Upregulated by PKC in MCF7 Human Breast Cancer Cells and Correlates Positively with PKCε in Patient Biopsies. Transl Oncol. 2019;12:561-575 pubmed 出版商
Kalsi K, Garnett J, Patkee W, Weekes A, Dockrell M, Baker E, et al. Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCζ-mediated phosphorylation of occludin. J Cell Mol Med. 2019;23:317-327 pubmed 出版商
Sun X, Fu X, Du M, Zhu M. Ex vivo gut culture for studying differentiation and migration of small intestinal epithelial cells. Open Biol. 2018;8: pubmed 出版商
Zhang Y, Zhang Y. Forkhead box C2 promotes the invasion ability of human trophoblast cells through Hedgehog (Hh) signaling pathway. Cell Biol Int. 2018;42:859-866 pubmed 出版商
Tsubouchi K, Minami K, Hayashi N, Yokoyama Y, Mori S, Yamamoto H, et al. The CD44 standard isoform contributes to radioresistance of pancreatic cancer cells. J Radiat Res. 2017;:1-11 pubmed 出版商
Jovov B, Reed C, Shaheen N, Pruitt A, Ferrell K, Orlando G, et al. Fragments of e-Cadherin as Biomarkers of Non-erosive Reflux Disease. Dig Dis Sci. 2018;63:628-635 pubmed 出版商
Wu Z, Guo L, Ge J, Zhang Z, Wei H, Zhou Q. Two serine residues of non-metastasis protein 23-H1 are critical in inhibiting signal transducer and activator of transcription 3 activity in human lung cancer cells. Oncol Lett. 2017;14:2475-2482 pubmed 出版商
Gruel N, Fuhrmann L, Lodillinsky C, Benhamo V, Mariani O, Cédenot A, et al. LIN7A is a major determinant of cell-polarity defects in breast carcinomas. Breast Cancer Res. 2016;18:23 pubmed 出版商
Lou N, Takano T, Pei Y, Xavier A, Goldman S, Nedergaard M. Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier. Proc Natl Acad Sci U S A. 2016;113:1074-9 pubmed 出版商
Sato F, Kubota Y, Natsuizaka M, Maehara O, Hatanaka Y, Marukawa K, et al. EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition. Cancer Biol Ther. 2015;16:933-40 pubmed 出版商
Hahn S, Jackstadt R, Siemens H, Hünten S, Hermeking H. SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition. EMBO J. 2013;32:3079-95 pubmed 出版商
Jackstadt R, Röh S, Neumann J, Jung P, Hoffmann R, Horst D, et al. AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer. J Exp Med. 2013;210:1331-50 pubmed 出版商
Angelucci C, Lama G, Iacopino F, Sica G. Leuprorelin acetate affects adhesion molecule expression in human prostate cancer cells. Int J Oncol. 2011;38:1501-9 pubmed 出版商
Zhou G, Hasina R, Wroblewski K, Mankame T, Doçi C, Lingen M. Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis. Cancer Prev Res (Phila). 2010;3:1493-502 pubmed 出版商
Darsigny M, Babeu J, Dupuis A, Furth E, Seidman E, Levy E, et al. Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice. PLoS ONE. 2009;4:e7609 pubmed 出版商
Guerini V, Sau D, Scaccianoce E, Rusmini P, Ciana P, Maggi A, et al. The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits prostate cancer cell migration through activation of the estrogen receptor beta subtype. Cancer Res. 2005;65:5445-53 pubmed
Palacios J, Honrado E, Osorio A, Cazorla A, Sarrio D, Barroso A, et al. Immunohistochemical characteristics defined by tissue microarray of hereditary breast cancer not attributable to BRCA1 or BRCA2 mutations: differences from breast carcinomas arising in BRCA1 and BRCA2 mutation carriers. Clin Cancer Res. 2003;9:3606-14 pubmed
Kim J, Hwang H, Yeo S, Ko S, Song S, Kim Y, et al. Morphologic evaluation and integrin expression profile of renal tubular cells cultured from percutaneous renal biopsy specimen. Ren Fail. 2001;23:21-9 pubmed
产品信息
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(4A2C7)
目录# :
33-4000
规格 :
100微克
价格 :
美国452.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunohistochemistry: 2-10 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: 1 µg/mL
物种 :
人类
克隆 :
4A2C7
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
免疫原 :
Recombinant MBP fusion protein corresponding to the cytoplasmic domain of human E-cadherin
格式 :
液体
应用w/稀释 :
Immunohistochemistry: 2-10 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: 1 µg/mL
别名 :
AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-Cadherin phospho; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; phospho cadherin 1; phospho E-Cadherin; phospho LCAM; phospho S838; phospho UVO; S840; S840 E-Cadherin; Ser840; Ser840 E-Cadherin; Um; UVO; Uvomorulin
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国