产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
SPARC单克隆抗体(ON1-1)
目录 :
33-5500
规格 :
100微克
价格 :
美国413.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
ON1-1
反应物种 :
人类, 大鼠, 犬, 牛, pigs , domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 28
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 犬; 图 6
Ozdal Kurt F, Tuglu I, Vatansever H, Tong S, Sen B, Deliloglu Gurhan S. The effect of different implant biomaterials on the behavior of canine bone marrow stromal cells during their differentiation into osteoblasts. Biotech Histochem. 2016;91:412-22 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Ozdal Kurt F, Sen B, Tuglu I, Vatansever S, Türk B, Deliloglu Gurhan I. Attachment and growth of dental pulp stem cells on dentin in presence of extra calcium. Arch Oral Biol. 2016;68:131-41 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Jokerst J, Chen Z, Xu L, Nolley R, Chang E, Mitchell B, et al. A Magnetic Bead-Based Sensor for the Quantification of Multiple Prostate Cancer Biomarkers. PLoS ONE. 2015;10:e0139484 pubmed 出版商
  • 免疫组化; 人类; 1:400; 图 1
Bertino E, Williams T, Nana Sinkam S, Shilo K, Chatterjee M, Mo X, et al. Stromal Caveolin-1 Is Associated With Response and Survival in a Phase II Trial of nab-Paclitaxel With Carboplatin for Advanced NSCLC Patients. Clin Lung Cancer. 2015;16:466-74 pubmed 出版商
  • 免疫组化; 犬; 图 5
Özdal Kurt F, TuÄŸlu I, Vatansever H, Tong S, DeliloÄŸlu Gürhan S. The effect of autologous bone marrow stromal cells differentiated on scaffolds for canine tibial bone reconstruction. Biotech Histochem. 2015;90:516-28 pubmed 出版商
  • 免疫组化; 人类; 1:100
Ren K, Yao N, Wang G, Tian L, Ma J, Shi X, et al. Vasculogenic mimicry: a new prognostic sign of human osteosarcoma. Hum Pathol. 2014;45:2120-9 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 图 1
Xu L, Ping F, Yin J, Xiao X, Xiang H, Ballantyne C, et al. Elevated plasma SPARC levels are associated with insulin resistance, dyslipidemia, and inflammation in gestational diabetes mellitus. PLoS ONE. 2013;8:e81615 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 3
Chen J, Espinosa I, Lin A, Liao O, van de Rijn M, West R. Stromal responses among common carcinomas correlated with clinicopathologic features. Clin Cancer Res. 2013;19:5127-35 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 10 ug/ml; 图 2
Triulzi T, Casalini P, Sandri M, Ratti M, Carcangiu M, Colombo M, et al. Neoplastic and stromal cells contribute to an extracellular matrix gene expression profile defining a breast cancer subtype likely to progress. PLoS ONE. 2013;8:e56761 pubmed 出版商
  • 免疫组化; 大鼠; 图 5
Ozturk F, Babacan H, Inan S, Gumus C. Effects of bisphosphonates on sutural bone formation and relapse: A histologic and immunohistochemical study. Am J Orthod Dentofacial Orthop. 2011;140:e31-41 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:6000; 图 1
Daugaard S, Christensen L, Høgdall E. Markers aiding the diagnosis of chondroid tumors: an immunohistochemical study including osteonectin, bcl-2, cox-2, actin, calponin, D2-40 (podoplanin), mdm-2, CD117 (c-kit), and YKL-40. APMIS. 2009;117:518-25 pubmed 出版商
  • 免疫组化; 人类
Andersen T, Sondergaard T, Skorzynska K, Dagnaes Hansen F, Plesner T, Hauge E, et al. A physical mechanism for coupling bone resorption and formation in adult human bone. Am J Pathol. 2009;174:239-47 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500
Hong S, Kelly D, Griffith M, Omura N, Li A, Li C, et al. Multiple genes are hypermethylated in intraductal papillary mucinous neoplasms of the pancreas. Mod Pathol. 2008;21:1499-507 pubmed 出版商
  • 免疫细胞化学; 人类; 5 ug/ml; 图 3
  • 免疫印迹; 人类; 图 2
Pan M, Chang H, Chuang L, Hung W. The nonsteroidal anti-inflammatory drug NS398 reactivates SPARC expression via promoter demethylation to attenuate invasiveness of lung cancer cells. Exp Biol Med (Maywood). 2008;233:456-62 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Infante J, Matsubayashi H, Sato N, Tonascia J, Klein A, Riall T, et al. Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma. J Clin Oncol. 2007;25:319-25 pubmed
  • 免疫组化; 人类; 1:200; 图 8B
  • 免疫印迹; 人类; 1:1000
Chlenski A, Liu S, Guerrero L, Yang Q, Tian Y, Salwen H, et al. SPARC expression is associated with impaired tumor growth, inhibited angiogenesis and changes in the extracellular matrix. Int J Cancer. 2006;118:310-6 pubmed
  • 免疫组化; 人类; 图 2
Sato N, Fukushima N, Maehara N, Matsubayashi H, Koopmann J, Su G, et al. SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions. Oncogene. 2003;22:5021-30 pubmed
Žlajpah M, Bostjancic E, Tepes B, Zidar N. Expression of Extracellular Matrix-Related Genes and Their Regulatory microRNAs in Problematic Colorectal Polyps. Cancers (Basel). 2020;12: pubmed 出版商
Laçin N, İzol S, Ipek F, Tuncer M. Ganoderma lucidum, a promising agent possessing antioxidant and anti-inflammatory effects for treating calvarial defects with graft application in rats. Acta Cir Bras. 2019;34:e201900904 pubmed 出版商
Laçin N, Deveci E. Short-term use of resveratrol in alloplastic graft material applied with calvarial bone defects in rats. Acta Cir Bras. 2019;34:e201900704 pubmed 出版商
Laçin N, İzol B, Ozkorkmaz E, Deveci B, Tuncer M. The effect of graft application and simvastatin treatment on tibial bone defect in rats. A histological and immunohistochemical study. Acta Cir Bras. 2019;34:e201900408 pubmed 出版商
López Moncada F, Torres M, Castellon E, Contreras H. Secreted protein acidic and rich in cysteine (SPARC) induces epithelial-mesenchymal transition, enhancing migration and invasion, and is associated with high Gleason score in prostate cancer. Asian J Androl. 2019;21:557-564 pubmed 出版商
Baloğlu M, Gokalp Ozkorkmaz E. Biochemical and immunohistochemical investigations on bone formation and remodelling in ovariectomized rats with tamoxifen citrate administration. Folia Morphol (Warsz). 2019;: pubmed 出版商
Laçin N, İzol B, Ozkorkmaz E, Deveci B, Tuncer M. The effect of graft application and allopurinol treatment on calvarial bone defect in rats1. Acta Cir Bras. 2019;34:e201900306 pubmed 出版商
Laçin N, İzol B, Tuncer M, Gokalp Ozkorkmaz E, Deveci B, Deveci E. Effects of formaldehyde on VEGF, MMP2, and Osteonectin levels in periodontal membrane and alveolar bone in the rats. Folia Morphol (Warsz). 2018;: pubmed 出版商
Andriani F, Landoni E, Mensah M, Facchinetti F, Miceli R, Tagliabue E, et al. Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer. BMC Cancer. 2018;18:899 pubmed 出版商
Higgins J, Wang L, Kambham N, Montgomery K, Mason V, Vogelmann S, et al. Gene expression in the normal adult human kidney assessed by complementary DNA microarray. Mol Biol Cell. 2004;15:649-56 pubmed
Fromigue O, Louis K, Dayem M, Milanini J, Pages G, Tartare Deckert S, et al. Gene expression profiling of normal human pulmonary fibroblasts following coculture with non-small-cell lung cancer cells reveals alterations related to matrix degradation, angiogenesis, cell growth and survival. Oncogene. 2003;22:8487-97 pubmed
产品信息
产品类型 :
抗体
产品名称 :
SPARC单克隆抗体(ON1-1)
目录# :
33-5500
规格 :
100微克
价格 :
美国413.00
克隆性 :
单克隆
纯度 :
离子交换层析
宿主 :
小鼠
反应物种 :
牛, 人类, 猪, 兔
应用 :
ELISA: Assay-dependent, Flow Cytometry: 1 µg/mL, Immunohistochemistry: 5-10 µg/mL, Western Blot: 5-10 µg/mL
物种 :
牛, 人类, 猪, 兔
克隆 :
ON1-1
抗体亚型 :
IgG1
储存 :
4° C
描述 :
SPARC gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
免疫原 :
全长牛骨骨结合素(SPARC)
格式 :
冻干
应用w/稀释 :
ELISA: Assay-dependent, Flow Cytometry: 1 µg/mL, Immunohistochemistry: 5-10 µg/mL, Western Blot: 5-10 µg/mL
别名 :
Basement membrane protein 40; basement-membrane protein 40; BM40; BM-40; Cysteine rich protein; OI17; ON; Osteonectin; osteonectin precursor; Secreted acidic cystein rich glycoprotein; secreted acidic cysteine rich glycoprotein; Secreted acidic cystein-rich glycoprotein (osteonectin); secreted protein acidic and cysteine rich; secreted protein acidic and rich in cysteine; Secreted protein acidic and rich in cysteine (SPARC); secreted protein, acidic, cysteine-rich (osteonectin); secreted protein, acidic, cysteine-rich [osteonectin]; SPARC
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国