产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
STAT5甲/乙单克隆抗体(ST5-8F7)
目录 :
33-5900
规格 :
100微克
价格 :
美国449.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
ST5-8F7
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
文章摘录数: 6
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Duensing A, Medeiros F, McConarty B, Joseph N, Panigrahy D, Singer S, et al. Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs). Oncogene. 2004;23:3999-4006 pubmed
|
| Fisher R, Slayton W, Chien C, Guthrie S, Bray C, Scott E. PU.1 supports proliferation of immature erythroid progenitors. Leuk Res. 2004;28:83-9 pubmed
|
Wu Z, Roberts M, Porter M, Walker F, Wherry E, Kelly J, et al. Viral FLIP impairs survival of activated T cells and generation of CD8+ T cell memory. J Immunol. 2004;172:6313-23 pubmed
| |
Higuchi M, Kieff E, Izumi K. The Epstein-Barr virus latent membrane protein 1 putative Janus kinase 3 (JAK3) binding domain does not mediate JAK3 association or activation in B-lymphoma or lymphoblastoid cell lines. J Virol. 2002;76:455-9 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
STAT5甲/乙单克隆抗体(ST5-8F7)
目录# :
33-5900
规格 :
100微克
价格 :
美国449.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 5 µg/mL, Western Blot: 1-3 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
ST5-8F7
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of, many cell ligands, such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/ BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
免疫原 :
A peptide corresponding to a conserved amino acid sequence found near the carboxy-terminus of murine STAT5. This peptide encompasses the conserved C-terminal tyrosine phosphorylation site (Y-694) of murine STAT5
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 5 µg/mL, Western Blot: 1-3 µg/mL
别名 :
AA959963; Mammary gland factor; mammary gland factor STAT5A; mammary gland factor STAT5B; mammary gland factor; transcription factor; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5a; Signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; Stat5a; Stat5b; transcription factor STAT5B
更多信息或购买 :
公司信息
赛默飞世尔