产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
细胞色素C单克隆抗体(7H8.2C12)
目录 :
33-8500
规格 :
200微克
价格 :
美国405.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
7H8.2C12
反应物种 :
人类, 小鼠, 大鼠, fruit fly , 非洲爪蛙, 国内马
应用 :
免疫印迹, 免疫组化, 免疫沉淀
更多信息或购买 :
文章摘录数: 21
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 非洲爪蛙; 1:1000; 图 7
Roque C, Wong H, Lin J, Holt C. Tumor protein Tctp regulates axon development in the embryonic visual system. Development. 2016;143:1134-48 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Stefano G, Mantione K, Capellan L, Casares F, Challenger S, Ramin R, et al. Morphine stimulates nitric oxide release in human mitochondria. J Bioenerg Biomembr. 2015;47:409-17 pubmed 出版商
  • 免疫沉淀; 人类
Hedgepeth S, Garcia M, Wagner L, Rodriguez A, Chintapalli S, Snyder R, et al. The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release. J Biol Chem. 2015;290:7304-13 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 15
Guerrero Beltrán C, Calderon Oliver M, Martínez Abundis E, Tapia E, Zarco Márquez G, Zazueta C, et al. Protective effect of sulforaphane against cisplatin-induced mitochondrial alterations and impairment in the activity of NAD(P)H: quinone oxidoreductase 1 and ? glutamyl cysteine ligase: studies in mitochondria isolated from rat kidney and in LLC-PK1 . Toxicol Lett. 2010;199:80-92 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000; 表 1
Zucchini Pascal N, De Sousa G, Rahmani R. Lindane and cell death: at the crossroads between apoptosis, necrosis and autophagy. Toxicology. 2009;256:32-41 pubmed 出版商
  • 免疫组化; fruit fly ; 1:200
  • 免疫印迹; fruit fly ; 1:500
Abdelwahid E, Yokokura T, Krieser R, Balasundaram S, Fowle W, White K. Mitochondrial disruption in Drosophila apoptosis. Dev Cell. 2007;12:793-806 pubmed
  • 免疫印迹; 大鼠; 1:400; 图 6
Tanaka S, Takehashi M, Iida S, Kitajima T, Kamanaka Y, Stedeford T, et al. Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation. J Neurochem. 2005;95:179-90 pubmed
  • 免疫印迹; 小鼠; 图 4
Abarca Rojano E, Rosas Medina P, Zamudio Cortéz P, Mondragón Flores R, Sánchez García F. Mycobacterium tuberculosis virulence correlates with mitochondrial cytochrome c release in infected macrophages. Scand J Immunol. 2003;58:419-27 pubmed
  • 免疫印迹; 大鼠; 1:200; 图 3
Olichon A, Emorine L, Descoins E, Pelloquin L, Brichese L, Gas N, et al. The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space. FEBS Lett. 2002;523:171-6 pubmed
  • 免疫印迹; 人类; 图 2
Tang D, Lahti J, Grenet J, Kidd V. Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism. J Biol Chem. 1999;274:7245-52 pubmed
Donati G, Ravà M, Filipuzzi M, Nicoli P, Cassina L, Verrecchia A, et al. Targeting mitochondrial respiration and the BCL2 family in high-grade MYC-associated B-cell lymphoma. Mol Oncol. 2021;: pubmed 出版商
Petkovic A, Jakovljevic V, Bradic J, Jeremic J, Jeremic N, Nikolic Turnic T, et al. The Effects of Potassium Cyanide on the Functional Recovery of Isolated Rat Hearts after Ischemia and Reperfusion: The Role of Oxidative Stress. Oxid Med Cell Longev. 2018;2018:5979721 pubmed 出版商
Chen Y, Aon M, Hsu Y, Soane L, Teng X, McCaffery J, et al. Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential. J Cell Biol. 2011;195:263-76 pubmed 出版商
Birks S, Danquah J, King L, Vlasak R, Gorecki D, Pilkington G. Targeting the GD3 acetylation pathway selectively induces apoptosis in glioblastoma. Neuro Oncol. 2011;13:950-60 pubmed 出版商
Andoniou C, Andrews D, Manzur M, Ricciardi Castagnoli P, Degli Esposti M. A novel checkpoint in the Bcl-2-regulated apoptotic pathway revealed by murine cytomegalovirus infection of dendritic cells. J Cell Biol. 2004;166:827-37 pubmed
Risso de Faverney C, Orsini N, de Sousa G, Rahmani R. Cadmium-induced apoptosis through the mitochondrial pathway in rainbow trout hepatocytes: involvement of oxidative stress. Aquat Toxicol. 2004;69:247-58 pubmed
Reiss U, Oskouian B, Zhou J, Gupta V, Sooriyakumaran P, Kelly S, et al. Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. J Biol Chem. 2004;279:1281-90 pubmed
Wilkinson B, Elam J, Fadool D, Hyson R. Afferent regulation of cytochrome-c and active caspase-9 in the avian cochlear nucleus. Neuroscience. 2003;120:1071-9 pubmed
Love D, Kochan J, Cathey R, Shin S, Hanover J, Kochran J. Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase. J Cell Sci. 2003;116:647-54 pubmed
Hetz C, Bono M, Barros L, Lagos R. Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae, induces apoptosis in some human cell lines. Proc Natl Acad Sci U S A. 2002;99:2696-701 pubmed
Yu F, Finley R, Raz A, Kim H. Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. J Biol Chem. 2002;277:15819-27 pubmed
产品信息
产品类型 :
抗体
产品名称 :
细胞色素C单克隆抗体(7H8.2C12)
目录# :
33-8500
规格 :
200微克
价格 :
美国405.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
Drosophila, Equine, Human, Mouse, Rabbit, Rat, Xenopus laevis
应用 :
Western Blot: 1:1,000
物种 :
Drosophila, Equine, Human, Mouse, Rabbit, Rat, Xenopus laevis
克隆 :
7H8.2C12
抗体亚型 :
IgG2b, kappa
储存 :
-20°C
描述 :
Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
免疫原 :
Equine Cytochrome c.
格式 :
液体
应用w/稀释 :
Western Blot: 1:1,000
别名 :
CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国