产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
细胞色素C单克隆抗体(7H8.2C12)
目录 :
33-8500
规格 :
200微克
价格 :
美国405.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
7H8.2C12
反应物种 :
人类, 小鼠, 大鼠, fruit fly , 非洲爪蛙, 国内马
应用 :
免疫印迹, 免疫组化, 免疫沉淀
更多信息或购买 :
文章摘录数: 21
出版应用/物种/样本/稀释 | 参考文献 |
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| Guerrero Beltrán C, Calderon Oliver M, Martínez Abundis E, Tapia E, Zarco Márquez G, Zazueta C, et al. Protective effect of sulforaphane against cisplatin-induced mitochondrial alterations and impairment in the activity of NAD(P)H: quinone oxidoreductase 1 and ? glutamyl cysteine ligase: studies in mitochondria isolated from rat kidney and in LLC-PK1 . Toxicol Lett. 2010;199:80-92 pubmed 出版商
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| Abdelwahid E, Yokokura T, Krieser R, Balasundaram S, Fowle W, White K. Mitochondrial disruption in Drosophila apoptosis. Dev Cell. 2007;12:793-806 pubmed
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| Tanaka S, Takehashi M, Iida S, Kitajima T, Kamanaka Y, Stedeford T, et al. Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation. J Neurochem. 2005;95:179-90 pubmed
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| Abarca Rojano E, Rosas Medina P, Zamudio Cortéz P, Mondragón Flores R, Sánchez García F. Mycobacterium tuberculosis virulence correlates with mitochondrial cytochrome c release in infected macrophages. Scand J Immunol. 2003;58:419-27 pubmed
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| Olichon A, Emorine L, Descoins E, Pelloquin L, Brichese L, Gas N, et al. The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space. FEBS Lett. 2002;523:171-6 pubmed
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| Tang D, Lahti J, Grenet J, Kidd V. Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism. J Biol Chem. 1999;274:7245-52 pubmed
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Andoniou C, Andrews D, Manzur M, Ricciardi Castagnoli P, Degli Esposti M. A novel checkpoint in the Bcl-2-regulated apoptotic pathway revealed by murine cytomegalovirus infection of dendritic cells. J Cell Biol. 2004;166:827-37 pubmed
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Risso de Faverney C, Orsini N, de Sousa G, Rahmani R. Cadmium-induced apoptosis through the mitochondrial pathway in rainbow trout hepatocytes: involvement of oxidative stress. Aquat Toxicol. 2004;69:247-58 pubmed
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Reiss U, Oskouian B, Zhou J, Gupta V, Sooriyakumaran P, Kelly S, et al. Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. J Biol Chem. 2004;279:1281-90 pubmed
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Wilkinson B, Elam J, Fadool D, Hyson R. Afferent regulation of cytochrome-c and active caspase-9 in the avian cochlear nucleus. Neuroscience. 2003;120:1071-9 pubmed
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Love D, Kochan J, Cathey R, Shin S, Hanover J, Kochran J. Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase. J Cell Sci. 2003;116:647-54 pubmed
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Hetz C, Bono M, Barros L, Lagos R. Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae, induces apoptosis in some human cell lines. Proc Natl Acad Sci U S A. 2002;99:2696-701 pubmed
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Yu F, Finley R, Raz A, Kim H. Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. J Biol Chem. 2002;277:15819-27 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
细胞色素C单克隆抗体(7H8.2C12)
目录# :
33-8500
规格 :
200微克
价格 :
美国405.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
Drosophila, Equine, Human, Mouse, Rabbit, Rat, Xenopus laevis
应用 :
Western Blot: 1:1,000
物种 :
Drosophila, Equine, Human, Mouse, Rabbit, Rat, Xenopus laevis
克隆 :
7H8.2C12
抗体亚型 :
IgG2b, kappa
储存 :
-20°C
描述 :
Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
免疫原 :
Equine Cytochrome c.
格式 :
液体
应用w/稀释 :
Western Blot: 1:1,000
别名 :
CG17903; CG17903-PA; CG17903-PB; CRF; CYC; CYC2; Cycs; CYCSA; Cyct-c-p; Cyt c; cyt c-p; cyt.c; CytC; Cyt-c; CYTC2; Cyt-c2; CytC-2; cyt-c-p; cytC-p; Cyt-c-p-PA; Cyt-c-p-PB; Cytochrome c; cytochrome c DC4; Cytochrome c proximal; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; Cytochrome c-2; cytochrome c-like; cytochrome c-like protein; Cytochrome c-proximal; cytochrome-c-p; Cytochrome-c-proximal; DC4; dCyt.C-p; DMc01; Dmel CG17903; Dmel_CG17903; hc1; HCS; l(2)k13905; lethal (2) k13905; LOC100341175; LOC100357840; MGC128356 protein; pDMc01; RH17228p; THC4
更多信息或购买 :
公司信息
赛默飞世尔