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African green monkey, Trachemys dorbigni, 日本大米鱼, 金鱼, Burton's mouthbrooder, turquoise killifish, 豚鼠, 人类, 小鼠, 大鼠, , , , pigs , 斑马鱼, , 家羊, 非洲爪蛙, domestic rabbit, 猕猴
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免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 其他, 免疫印迹基因敲除验证
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文章摘录数: 562
  • 免疫组化; turquoise killifish; 图 s2f
Coolen M, Labusch M, Mannioui A, Bally Cuif L. Mosaic Heterochrony in Neural Progenitors Sustains Accelerated Brain Growth and Neurogenesis in the Juvenile Killifish N. furzeri. Curr Biol. 2020;30:736-745.e4 pubmed 出版商
  • 其他; 斑马鱼; 1:100
Wangen J, Green R. Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides. elife. 2020;9: pubmed 出版商
  • 其他; 斑马鱼; 1:100
Arora P, Dongre S, Raman R, Sonawane M. Stepwise polarisation of developing bilayered epidermis is mediated by aPKC and E-cadherin in zebrafish. elife. 2020;9: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 5b
Findlay A, McKie L, Keighren M, Clementson Mobbs S, Sanchez Pulido L, Wells S, et al. Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function. Sci Rep. 2020;10:437 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:200; 图 7b3
Thouvenin O, Keiser L, Cantaut Belarif Y, Carbó Tano M, Verweij F, Jurisch Yaksi N, et al. Origin and role of the cerebrospinal fluid bidirectional flow in the central canal. elife. 2020;9: pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 5d
Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; 人类; 图 6g
Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1e
Luong P, Hedl M, Yan J, Zuo T, Fu T, Jiang X, et al. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. elife. 2018;7: pubmed 出版商
  • 免疫细胞化学; 犬; 1:1000; 图 s4b
  • 免疫细胞化学; 人类; 1:1000; 图 s2c
Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed 出版商
  • 免疫组化; 大鼠; 1:500; 图 2
Liang F, Hwang J, Tang N, Hunziker W. Juxtanodin in retinal pigment epithelial cells: Expression and biological activities in regulating cell morphology and actin cytoskeleton organization. J Comp Neurol. 2018;526:205-215 pubmed 出版商
  • 免疫印迹; 小鼠; 1:400; 图 4f, 4h
Boussadia B, Lakhal L, Payrastre L, Ghosh C, Pascussi J, Gangarossa G, et al. Pregnane X Receptor Deletion Modifies Recognition Memory and Electroencephalographic Activity. Neuroscience. 2018;370:130-138 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1f
Pelz L, Purfürst B, Rathjen F. The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice. J Biol Chem. 2017;292:21490-21503 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2 - s1b
Connell M, Chen H, Jiang J, Kuan C, Fotovati A, Chu T, et al. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, et al. CRB3 downregulation confers breast cancer stem cell traits through TAZ/?-catenin. Oncogenesis. 2017;6:e322 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 1g
Kharfallah F, Guyot M, El Hassan A, Allache R, Merello E, De Marco P, et al. Scribble1 plays an important role in the pathogenesis of neural tube defects through its mediating effect of Par-3 and Vangl1/2 localization. Hum Mol Genet. 2017;26:2307-2320 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 s1a, s1e
Ahmed S, Macara I. The Par3 polarity protein is an exocyst receptor essential for mammary cell survival. Nat Commun. 2017;8:14867 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:200; 图 3c
Xavier A, Fontaine R, Bloch S, Affaticati P, Jenett A, Demarque M, et al. Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates). J Comp Neurol. 2017;525:2265-2283 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 5A
Geng Z, Walsh P, Truong V, Hill C, Ebeling M, Kapphahn R, et al. Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS ONE. 2017;12:e0173575 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Zhang W, Li H, Ogando D, Li S, Feng M, Price F, et al. Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium. EBioMedicine. 2017;16:292-301 pubmed 出版商
  • 免疫组化; 大鼠; 1:100; 图 1
  • 免疫印迹; 大鼠; 1:250; 图 2a
Dukic A, Haugen L, Pidoux G, Leithe E, Bakke O, Tasken K. A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells. Cell Signal. 2017;32:1-11 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1a
  • 免疫组化; 人类; 图 6a
  • 免疫印迹; 人类; 图 1a
Lesage J, Suarez Carmona M, Neyrinck Leglantier D, Grelet S, Blacher S, Hunziker W, et al. Zonula occludens-1/NF-?B/CXCL8: a new regulatory axis for tumor angiogenesis. FASEB J. 2017;31:1678-1688 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 1a
Priya R, Liang X, Teo J, Duszyc K, Yap A, Gomez G. ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Mol Biol Cell. 2017;28:12-20 pubmed 出版商
  • 免疫印迹基因敲除验证; 大鼠; 图 4d
  • 免疫细胞化学; 大鼠; 图 5
Van Itallie C, Tietgens A, Anderson J. Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1. Mol Biol Cell. 2017;28:524-534 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 2b
Wang M, Nagle R, Knudsen B, Rogers G, Cress A. A basal cell defect promotes budding of prostatic intraepithelial neoplasia. J Cell Sci. 2017;130:104-110 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 2
Shadforth A, Suzuki S, Theodoropoulos C, Richardson N, Chirila T, Harkin D. A Bruch's membrane substitute fabricated from silk fibroin supports the function of retinal pigment epithelial cells in vitro. J Tissue Eng Regen Med. 2017;11:1915-1924 pubmed 出版商
  • 免疫组化; domestic rabbit; 图 4
  • 免疫印迹; domestic rabbit; 图 3
Kageyama T, Hayashi R, Hara S, Yoshikawa K, Ishikawa Y, Yamato M, et al. Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics. J Tissue Eng Regen Med. 2017;11:1057-1064 pubmed 出版商
  • 免疫组化; 小鼠; 图 3d
Yuan J, Cha J, Deng W, Bartos A, Sun X, Ho H, et al. Planar cell polarity signaling in the uterus directs appropriate positioning of the crypt for embryo implantation. Proc Natl Acad Sci U S A. 2016;113:E8079-E8088 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 6e
  • 免疫印迹; 小鼠; 1:1000; 图 6a
  • 免疫印迹; 人类; 1:1000; 图 2a
Lin Z, Zhang Y, Xia Y, Xu X, Jiao X, Sun J. Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway. J Biol Chem. 2016;291:26837-26849 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6d
Wufuer M, Lee G, Hur W, Jeon B, Kim B, Choi T, et al. Skin-on-a-chip model simulating inflammation, edema and drug-based treatment. Sci Rep. 2016;6:37471 pubmed 出版商
  • 免疫组化; 小鼠; 1:300; 表 1
Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed 出版商
  • 免疫组化; 斑马鱼; 1:150; 图 s5a
Kantarci H, Gerberding A, Riley B. Spemann organizer gene Goosecoid promotes delamination of neuroblasts from the otic vesicle. Proc Natl Acad Sci U S A. 2016;113:E6840-E6848 pubmed
  • 免疫组化-石蜡切片; 斑马鱼; 1:100; 图 4a
Cronan M, Beerman R, ROSENBERG A, Saelens J, Johnson M, Oehlers S, et al. Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection. Immunity. 2016;45:861-876 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 表 2
Kilic O, Pamies D, Lavell E, Schiapparelli P, Feng Y, Hartung T, et al. Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis. Lab Chip. 2016;16:4152-4162 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100; 图 s2
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 4
Neckel P, Mattheus U, Hirt B, Just L, Mack A. Large-scale tissue clearing (PACT): Technical evaluation and new perspectives in immunofluorescence, histology, and ultrastructure. Sci Rep. 2016;6:34331 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 5h
  • 免疫组化-石蜡切片; 人类; 1:100; 图 s10h
Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, et al. Frizzled proteins are colonic epithelial receptors for C. difficile toxin B. Nature. 2016;538:350-355 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 5c
Priya R, Wee K, Budnar S, Gomez G, Yap A, Michael M. Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II. Cell Cycle. 2016;15:3033-3041 pubmed
  • 免疫细胞化学; 人类; 图 2a
Gallego Delgado J, Basu Roy U, Ty M, Alique M, Fernandez Arias C, Movila A, et al. Angiotensin receptors and ?-catenin regulate brain endothelial integrity in malaria. J Clin Invest. 2016;126:4016-4029 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1d
  • 免疫印迹; 人类; 1:1000; 图 5a
Kuan W, Bennett N, He X, Skepper J, Martynyuk N, Wijeyekoon R, et al. ?-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function. Exp Neurol. 2016;285:72-81 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 3a
Coburn L, Lopez H, Caldwell B, Moussa E, Yap C, Priya R, et al. Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates. Mol Biol Cell. 2016;27:3436-3448 pubmed
  • 免疫组化-石蜡切片; 人类; 图 1
  • 免疫印迹; 人类; 图 1
Yuki T, Tobiishi M, Kusaka Kikushima A, Ota Y, Tokura Y. Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17. PLoS ONE. 2016;11:e0161759 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s2
  • 免疫印迹; 人类; 图 s1
Huang L, Stuart C, Takeda K, D Agnillo F, Golding B. Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5. PLoS ONE. 2016;11:e0160875 pubmed 出版商
  • 免疫细胞化学; 犬; 1:200; 图 5
  • 免疫印迹; 犬; 1:1000; 图 3a
Ronaghan N, Shang J, Iablokov V, Zaheer R, Colarusso P, Dion S, et al. The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction. Am J Physiol Gastrointest Liver Physiol. 2016;311:G466-79 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 s3
Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016;7:12309 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1e
  • 免疫细胞化学; 人类; 图 2c
  • 免疫印迹; 人类; 1:4000; 图 3a
Babkair H, Yamazaki M, Uddin M, Maruyama S, Abe T, Essa A, et al. Aberrant expression of the tight junction molecules claudin-1 and zonula occludens-1 mediates cell growth and invasion in oral squamous cell carcinoma. Hum Pathol. 2016;57:51-60 pubmed 出版商
  • 免疫组化; 小鼠; 图 s6
Grahammer F, Wigge C, Schell C, Kretz O, Patrakka J, Schneider S, et al. A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes. JCI Insight. 2016;1: pubmed 出版商
  • 免疫组化; 小鼠; 图 3o
Pollock L, Gupta N, Chen X, Luna E, McDermott B. Supervillin Is a Component of the Hair Cell's Cuticular Plate and the Head Plates of Organ of Corti Supporting Cells. PLoS ONE. 2016;11:e0158349 pubmed 出版商
  • 免疫组化; 人类; 图 4
He Z, Forest F, Gain P, Rageade D, Bernard A, Acquart S, et al. 3D map of the human corneal endothelial cell. Sci Rep. 2016;6:29047 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4
Folmsbee S, Wilcox D, Tyberghein K, De Bleser P, Tourtellotte W, van Hengel J, et al. ?T-catenin in restricted brain cell types and its potential connection to autism. J Mol Psychiatry. 2016;4:2 pubmed 出版商
  • 免疫细胞化学; 人类; 10 ug/ml; 图 1
Booth J, Duggan E, Patel V, Langer M, Wu W, Braun A, et al. Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung models. Microbes Infect. 2016;18:615-626 pubmed 出版商
  • 免疫组化; 人类; 图 3a
Li Q, Sodroski C, Lowey B, Schweitzer C, Cha H, Zhang F, et al. Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition. Proc Natl Acad Sci U S A. 2016;113:7620-5 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 5
  • 流式细胞仪; 人类; 图 3
  • 免疫细胞化学; 人类; 图 3
Du C, Narayanan K, Leong M, Ibrahim M, Chua Y, Khoo V, et al. Functional Kidney Bioengineering with Pluripotent Stem-Cell-Derived Renal Progenitor Cells and Decellularized Kidney Scaffolds. Adv Healthc Mater. 2016;5:2080-91 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 8b
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez Carballo A, Gutierrez Uzquiza A, et al. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38? activation, while it impairs tumor growth through p38?-independent mechanisms. Oncotarget. 2016;7:45060-45078 pubmed 出版商
  • 免疫组化-冰冻切片; 斑马鱼; 1:200; 图 2
Hudish L, Galati D, Ravanelli A, Pearson C, Huang P, Appel B. miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling. Development. 2016;143:2292-304 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4
Santos A, Durkin C, Helaine S, Boucrot E, Holden D. Clustered Intracellular Salmonella enterica Serovar Typhimurium Blocks Host Cell Cytokinesis. Infect Immun. 2016;84:2149-2158 pubmed 出版商
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Teo W, Merino V, Cho S, Korangath P, Liang X, Wu R, et al. HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24. Oncogene. 2016;35:5539-5551 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 1
Takeo Y, Kurabayashi N, Nguyen M, Sanada K. The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway. Sci Rep. 2016;6:25180 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 2
Zoschke C, Ulrich M, Sochorová M, Wolff C, Vavrova K, Ma N, et al. The barrier function of organotypic non-melanoma skin cancer models. J Control Release. 2016;233:10-8 pubmed 出版商
  • 免疫细胞化学; pigs ; 1:50; 图 3
Di Lauro S, Rodriguez Crespo D, Gayoso M, Garcia Gutierrez M, Pastor J, Srivastava G, et al. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Mol Vis. 2016;22:243-53 pubmed
  • 免疫细胞化学; 小鼠; 1:250; 图 4
Martovetsky G, Bush K, Nigam S. Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers. Drug Metab Dispos. 2016;44:1050-60 pubmed 出版商
  • 免疫组化-自由浮动切片; 斑马鱼; 1:200; 图 7
Sepich D, Solnica Krezel L. Intracellular Golgi Complex organization reveals tissue specific polarity during zebrafish embryogenesis. Dev Dyn. 2016;245:678-91 pubmed 出版商
  • 免疫细胞化学; pigs ; 1:100; 图 3
Kwon J, Jeong S, Choi I, Kim N. ADAM10 Is Involved in Cell Junction Assembly in Early Porcine Embryo Development. PLoS ONE. 2016;11:e0152921 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 s1
Lee N, Fok K, White A, Wilson N, O Leary C, Cox H, et al. Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Nat Commun. 2016;7:11082 pubmed 出版商
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Djuric I, Siebrasse J, Schulze U, Granado D, Schlüter M, Kubitscheck U, et al. The C-terminal domain controls the mobility of Crumbs 3 isoforms. Biochim Biophys Acta. 2016;1863:1208-17 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4
Ichise H, Ichise T, Yoshida N. Phospholipase Cγ2 Is Required for Luminal Expansion of the Epididymal Duct during Postnatal Development in Mice. PLoS ONE. 2016;11:e0150521 pubmed 出版商
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Dora K, Stanley C, Al Jaaly E, Fiorentino F, Ascione R, Reeves B, et al. Isolated Human Pulmonary Artery Structure and Function Pre- and Post-Cardiopulmonary Bypass Surgery. J Am Heart Assoc. 2016;5: pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 3
Raredon M, Ghaedi M, Calle E, Niklason L. A Rotating Bioreactor for Scalable Culture and Differentiation of Respiratory Epithelium. Cell Med. 2015;7:109-21 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1
Wiltshire R, Nelson V, Kho D, Angel C, O Carroll S, Graham E. Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors. Sci Rep. 2016;6:19814 pubmed 出版商
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Grego Bessa J, Bloomekatz J, Castel P, Omelchenko T, Baselga J, Anderson K. The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium. elife. 2016;5:e12034 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Forest F, Thuret G, Gain P, Dumollard J, Peoc h M, Perrache C, et al. Optimization of immunostaining on flat-mounted human corneas. Mol Vis. 2015;21:1345-56 pubmed
  • 免疫印迹; 犬; 1:2000; 图 1
Tien S, Lee H, Yang Y, Lin M, Chen Y, Chang Z. The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42. Nat Commun. 2016;7:10420 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2
Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, et al. A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development. J Biol Chem. 2016;291:5817-31 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200; 图 8
Yang S, Krug S, Heitmann J, Hu L, Reinhold A, Sauer S, et al. Analgesic drug delivery via recombinant tissue plasminogen activator and microRNA-183-triggered opening of the blood-nerve barrier. Biomaterials. 2016;82:20-33 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 4
  • 免疫印迹; 小鼠; 图 4
Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 4d
  • 免疫印迹; 小鼠; 1:2000; 图 4b
Shi Y, Liu T, Fu J, Xu W, Wu L, Hou A, et al. Vitamin D/VDR signaling attenuates lipopolysaccharide‑induced acute lung injury by maintaining the integrity of the pulmonary epithelial barrier. Mol Med Rep. 2016;13:1186-94 pubmed 出版商
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Sarró E, Jacobs Cachá C, Itarte E, Meseguer A. A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells. Toxicol Appl Pharmacol. 2012;258:275-87 pubmed 出版商
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Knauf F, Ko N, Jiang Z, Robertson W, Van Itallie C, Anderson J, et al. Net intestinal transport of oxalate reflects passive absorption and SLC26A6-mediated secretion. J Am Soc Nephrol. 2011;22:2247-55 pubmed 出版商
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Lu Z, Ghosh S, Wang Z, Hunter T. Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. Cancer Cell. 2003;4:499-515 pubmed
Rafiee P, Ogawa H, Heidemann J, Li M, Aslam M, Lamirand T, et al. Isolation and characterization of human esophageal microvascular endothelial cells: mechanisms of inflammatory activation. Am J Physiol Gastrointest Liver Physiol. 2003;285:G1277-92 pubmed
Witt K, Mark K, Hom S, Davis T. Effects of hypoxia-reoxygenation on rat blood-brain barrier permeability and tight junctional protein expression. Am J Physiol Heart Circ Physiol. 2003;285:H2820-31 pubmed
Anders M, Christian C, McMahon M, McCormick F, Korn W. Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells. Cancer Res. 2003;63:2088-95 pubmed
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产品类型 :
产品名称 :
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宿主 :
反应物种 :
狗, 人类, 猕猴
应用 :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5-10 µg/mL, Immunofluorescence: 5-10 µg/mL, Western Blot: 1-2 µg/mL
物种 :
狗, 人类, 猕猴
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描述 :
ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
免疫原 :
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
格式 :
应用w/稀释 :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 5-10 µg/mL, Immunofluorescence: 5-10 µg/mL, Western Blot: 1-2 µg/mL
别名 :
BOS_20285; DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); Tight junction protein ZO-1; Tjp1; ZO1; ZO-1; zona occludens 1; Zona occludens protein 1; zonula occludens 1 protein; Zonula occludens protein 1
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公司总部: 美国