产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ZO-1单克隆抗体(ZO1-1A12), 异硫氰酸荧光素
目录 :
33-9111
规格 :
100微克
价格 :
美国439
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
ZO1-1A12
反应物种 :
人类, 小鼠, 大鼠, 犬, 斑马鱼
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 35
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 4
Campos Y, Qiu X, Gomero E, Wakefield R, Horner L, Brutkowski W, et al. Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier. Nat Commun. 2016;7:11876 pubmed 出版商
  • 免疫组化; 小鼠; 图 6
Pak J, Lee E, CRAFT C. The retinal phenotype of Grk1-/- is compromised by a Crb1 rd8 mutation. Mol Vis. 2015;21:1281-94 pubmed
  • 免疫组化-冰冻切片; 大鼠; 1:100
Tang E, Mok K, Lee W, Cheng C. EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study. Endocrinology. 2015;156:680-93 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
Ferrer M, Corneo B, Davis J, Wan Q, Miyagishima K, King R, et al. A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium. Stem Cells Transl Med. 2014;3:911-22 pubmed 出版商
  • 免疫组化-冰冻切片; 斑马鱼
Araya C, Tawk M, Girdler G, Costa M, Carmona Fontaine C, Clarke J. Mesoderm is required for coordinated cell movements within zebrafish neural plate in vivo. Neural Dev. 2014;9:9 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
Qian X, Mruk D, Cheng C. Rai14 (retinoic acid induced protein 14) is involved in regulating f-actin dynamics at the ectoplasmic specialization in the rat testis*. PLoS ONE. 2013;8:e60656 pubmed 出版商
  • 免疫细胞化学; 人类
Sugimoto J, Sugimoto M, BERNSTEIN H, Jinno Y, Schust D. A novel human endogenous retroviral protein inhibits cell-cell fusion. Sci Rep. 2013;3:1462 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100
Lydka M, Bilinska B, Cheng C, Mruk D. Tumor necrosis factor ?-mediated restructuring of the Sertoli cell barrier in vitro involves matrix metalloprotease 9 (MMP9), membrane-bound intercellular adhesion molecule-1 (ICAM-1) and the actin cytoskeleton. Spermatogenesis. 2012;2:294-303 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:50
Keay S, Leitzell S, Ochrzcin A, Clements G, Zhan M, Johnson D. A mouse model for interstitial cystitis/painful bladder syndrome based on APF inhibition of bladder epithelial repair: a pilot study. BMC Urol. 2012;12:17 pubmed
  • 免疫细胞化学; 人类; 图 6
Edelstein A, Fink D, Musch M, Valuckaite V, Zaborina O, Grubjesic S, et al. Protective effects of nonionic triblock copolymers on bile acid-mediated epithelial barrier disruption. Shock. 2011;36:451-7 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Wassmer S, Moxon C, Taylor T, Grau G, Molyneux M, Craig A. Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF. Cell Microbiol. 2011;13:198-209 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:50; 表 1
Su L, Cheng C, Mruk D. Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo. Int J Biochem Cell Biol. 2010;42:1864-75 pubmed 出版商
  • 流式细胞仪; 人类; 表 2
Semenov O, Koestenbauer S, Riegel M, Zech N, Zimmermann R, Zisch A, et al. Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation. Am J Obstet Gynecol. 2010;202:193.e1-193.e13 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:5; 图 4
  • 免疫印迹; 大鼠; 1:500; 图 7
Sobarzo C, Lustig L, Ponzio R, Suescun M, Denduchis B. Effects of di(2-ethylhexyl) phthalate on gap and tight junction protein expression in the testis of prepubertal rats. Microsc Res Tech. 2009;72:868-77 pubmed 出版商
  • 免疫组化; 大鼠; 图 5
Morishige N, Ko J, Liu Y, Chikama T, Nishida T. Localization of semaphorin 3A in the rat cornea. Exp Eye Res. 2008;86:669-74 pubmed 出版商
  • 免疫细胞化学; 人类
Roberts C, Rivera B, Grzybowski D, Mahmoud A, Weber P. Effect of low fluence diode laser irradiation on the hydraulic conductivity of perfused trabecular meshwork endothelial cell monolayers. Curr Eye Res. 2007;32:625-38 pubmed
  • 免疫组化-冰冻切片; 大鼠; 1:100; 表 1
Xia W, Wong C, Lee N, Lee W, Cheng C. Disruption of Sertoli-germ cell adhesion function in the seminiferous epithelium of the rat testis can be limited to adherens junctions without affecting the blood-testis barrier integrity: an in vivo study using an androgen suppression model. J Cell Physiol. 2005;205:141-57 pubmed
  • 免疫组化; 大鼠; 图 9
Siu M, Mruk D, Lee W, Cheng C. Adhering junction dynamics in the testis are regulated by an interplay of beta 1-integrin and focal adhesion complex-associated proteins. Endocrinology. 2003;144:2141-63 pubmed
Li Y, Wei J, Liu H, Wang K, Jin S, Su Z, et al. An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity. Cell Rep. 2022;39:110656 pubmed 出版商
Becker H, Jamin C, Bervoets L, Boleij A, Xu P, Pierik M, et al. Higher Prevalence of Bacteroides fragilis in Crohn's Disease Exacerbations and Strain-Dependent Increase of Epithelial Resistance. Front Microbiol. 2021;12:598232 pubmed 出版商
Matsumoto H, Mukai R, Hoshino J, Oda M, Matsuzaki T, Ishizaki Y, et al. Choroidal congestion mouse model: Could it serve as a pachychoroid model?. PLoS ONE. 2021;16:e0246115 pubmed 出版商
Ren Y, Dong X, Zhao H, Feng J, Chen B, Zhou Y, et al. Myeloid-derived suppressor cells improve corneal graft survival through suppressing angiogenesis and lymphangiogenesis. Am J Transplant. 2021;21:552-566 pubmed 出版商
Lu Y, Deng R, You H, Xu Y, Antos C, Sun J, et al. Asymmetric Stratification-Induced Polarity Loss and Coordinated Individual Cell Movements Drive Directional Migration of Vertebrate Epithelium. Cell Rep. 2020;33:108246 pubmed 出版商
Miller P, Chen C, Wang Y, Gao E, Shuler M. Multiorgan microfluidic platform with breathable lung chamber for inhalation or intravenous drug screening and development. Biotechnol Bioeng. 2020;117:486-497 pubmed 出版商
Araya C, Häkkinen H, Carcamo L, Cerda M, Savy T, Rookyard C, et al. Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate. Sci Rep. 2019;9:1835 pubmed 出版商
Angulo Urarte A, Casado P, Castillo S, Kobialka P, Kotini M, Figueiredo A, et al. Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility. Nat Commun. 2018;9:4826 pubmed 出版商
Miller P, Shuler M. Design and demonstration of a pumpless 14 compartment microphysiological system. Biotechnol Bioeng. 2016;113:2213-27 pubmed 出版商
Wan H, Mruk D, Wong C, Cheng C. Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier function by affecting F-actin organization via p-FAK-Tyr(407): an in vitro study. Endocrinology. 2014;155:249-62 pubmed 出版商
Qian X, Mruk D, Wong E, Lie P, Cheng C. Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes. Endocrinology. 2013;154:1907-20 pubmed 出版商
Raiko L, Siljamäki E, Mahoney M, Putaala H, Suominen E, Peltonen J, et al. Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca(2+) /Mn(2+) ATPase SPCA1 in cultured keratinocytes. Exp Dermatol. 2012;21:586-91 pubmed 出版商
Kuo T, Chen C, Baron D, Onder T, Loewer S, Almeida S, et al. Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nat Cell Biol. 2011;13:1214-23 pubmed 出版商
Lie P, Cheng C, Mruk D. Interleukin-1alpha is a regulator of the blood-testis barrier. FASEB J. 2011;25:1244-53 pubmed 出版商
Sarkar O, Mathur P, Cheng C, Mruk D. Interleukin 1 alpha (IL1A) is a novel regulator of the blood-testis barrier in the rat. Biol Reprod. 2008;78:445-54 pubmed
Lie P, Xia W, Wang C, Mruk D, Yan H, Wong C, et al. Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes. J Endocrinol. 2006;191:571-86 pubmed
Bandyopadhyay B, Swaim W, Liu X, Redman R, Patterson R, Ambudkar I. Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. J Biol Chem. 2005;280:12908-16 pubmed
产品信息
产品类型 :
抗体
产品名称 :
ZO-1单克隆抗体(ZO1-1A12), 异硫氰酸荧光素
目录# :
33-9111
规格 :
100微克
定价 :
美国439
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
狗, 人类
应用 :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 1-10 µg/mL, Western Blot: 1-2 µg/mL
物种 :
狗, 人类
克隆 :
ZO1-1A12
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark
描述 :
ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
免疫原 :
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
格式 :
液体
应用w/稀释 :
ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 1-10 µg/mL, Western Blot: 1-2 µg/mL
别名 :
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国