产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
NFkB p65单克隆抗体(2A12A7)
目录 :
33-9900
规格 :
100微克
价格 :
美国482
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2A12A7
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-自由浮动切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 6a
Niu Q, Liu Z, Alamer E, Fan X, Chen H, Endsley J, et al. Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV. J Clin Invest. 2019;129:3361-3373 pubmed 出版商
  • 免疫印迹; 人类
Lee Y, Wang E, Kumar N, Glickman R. Ursolic acid differentially modulates apoptosis in skin melanoma and retinal pigment epithelial cells exposed to UV-VIS broadband radiation. Apoptosis. 2014;19:816-28 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 6
  • 免疫细胞化学; 小鼠; 图 5
  • 免疫印迹; 小鼠; 图 1
Herkenham M, Rathore P, Brown P, Listwak S. Cautionary notes on the use of NF-?B p65 and p50 antibodies for CNS studies. J Neuroinflammation. 2011;8:141 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Chen M, Tsai T, Lin Y, Tsai Y, Wang L, Lee M, et al. Antipsychotic drugs suppress the AKT/NF-?B pathway and regulate the differentiation of T-cell subsets. Immunol Lett. 2011;140:81-91 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Jagla B, Aulner N, Kelly P, Song D, Volchuk A, Zatorski A, et al. Sequence characteristics of functional siRNAs. RNA. 2005;11:864-72 pubmed
Indukuri R, Hases L, Archer A, Williams C. Estrogen Receptor Beta Influences the Inflammatory p65 Cistrome in Colon Cancer Cells. Front Endocrinol (Lausanne). 2021;12:650625 pubmed 出版商
Krajewski A, Gagat M, Mikołajczyk K, Izdebska M, Zuryn A, Grzanka A. Cyclin F Downregulation Affects Epithelial-Mesenchymal Transition Increasing Proliferation and Migration of the A-375 Melanoma Cell Line. Cancer Manag Res. 2020;12:13085-13097 pubmed 出版商
Alamer E, Zhong C, Liu Z, Niu Q, Long F, Guo L, et al. Epigenetic Suppression of HIV in Myeloid Cells by the BRD4-Selective Small Molecule Modulator ZL0580. J Virol. 2020;94: pubmed 出版商
Mejhert N, Kuruvilla L, Gabriel K, Elliott S, Guie M, Wang H, et al. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Mol Cell. 2020;77:1251-1264.e9 pubmed 出版商
Gisbert Ferrándiz L, Salvador P, Ortiz Masia D, Macías Ceja D, Orden S, Esplugues J, et al. A Single Nucleotide Polymorphism in the Vitamin D Receptor Gene Is Associated With Decreased Levels of the Protein and a Penetrating Pattern in Crohn's Disease. Inflamm Bowel Dis. 2018;24:1462-1470 pubmed 出版商
Alegre F, Moragrega A, Polo M, Marti Rodrigo A, Esplugues J, Blas García A, et al. Role of p62/SQSTM1 beyond autophagy: a lesson learned from drug-induced toxicity in vitro. Br J Pharmacol. 2017;: pubmed 出版商
McDonald K, Cooper S, Danielzak L, Leask R. Glycocalyx Degradation Induces a Proinflammatory Phenotype and Increased Leukocyte Adhesion in Cultured Endothelial Cells under Flow. PLoS ONE. 2016;11:e0167576 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
NFkB p65单克隆抗体(2A12A7)
目录# :
33-9900
规格 :
100微克
定价 :
美国482
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
ChIP assay: 3 µg/mL, ELISA: Assay-dependent, Gel Shift: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 0.5 - 1 µg/mL
物种 :
人类, 小鼠
克隆 :
2A12A7
抗体亚型 :
IgG2a
储存 :
-20°C
描述 :
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.
免疫原 :
Recombinant protein (~175 amino acids) from the C-terminal portion of human NF-kappa-B (p65).
格式 :
液体
应用w/稀释 :
ChIP assay: 3 µg/mL, ELISA: Assay-dependent, Gel Shift: Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 0.5 - 1 µg/mL
别名 :
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国