产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor™ 488
目录 :
339188
规格 :
100微克
价格 :
美国490
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF488
克隆名称 :
ZO1-1A12
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 2.5 ug/ml
Uehara H, Zhang X, Pereira F, Narendran S, Choi S, Bhuvanagiri S, et al. Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy. elife. 2021;10: pubmed 出版商
  • 免疫组化; 小鼠; 图 7
Sun Y, Wu D, Zeng W, Chen Y, Guo M, Lu B, et al. The Role of Intestinal Dysbacteriosis Induced Arachidonic Acid Metabolism Disorder in Inflammaging in Atherosclerosis. Front Cell Infect Microbiol. 2021;11:618265 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 s1g
Hempt C, Hirsch C, Hannig Y, Rippl A, Wick P, Buerki Thurnherr T. Investigating the effects of differently produced synthetic amorphous silica (E 551) on the integrity and functionality of the human intestinal barrier using an advanced in vitro co-culture model. Arch Toxicol. 2021;95:837-852 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 4c
Roy A, Murphy R, Deng M, MacDonald J, Bammler T, Aldinger K, et al. PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; 人类; 图 7e
Rohnalter V, Roth K, Finkernagel F, Adhikary T, Obert J, Dorzweiler K, et al. A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype. Oncotarget. 2015;6:40005-25 pubmed 出版商
  • 免疫细胞化学; 犬; 5 ug/ml
Rother J, Büchsenschütz Göbeler M, Nöding H, Steltenkamp S, Samwer K, Janshoff A. Cytoskeleton remodelling of confluent epithelial cells cultured on porous substrates. J R Soc Interface. 2015;12: pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:100; 图 S3
Mok K, Mruk D, Cheng C. rpS6 regulates blood-testis barrier dynamics through Akt-mediated effects on MMP-9. J Cell Sci. 2014;127:4870-82 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000
Liu Z, Yu N, Holz F, Yang F, Stanzel B. Enhancement of retinal pigment epithelial culture characteristics and subretinal space tolerance of scaffolds with 200 nm fiber topography. Biomaterials. 2014;35:2837-50 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Bastiaans J, van Meurs J, van Holten Neelen C, Nagtzaam N, van Hagen P, Chambers R, et al. Thrombin induces epithelial-mesenchymal transition and collagen production by retinal pigment epithelial cells via autocrine PDGF-receptor signaling. Invest Ophthalmol Vis Sci. 2013;54:8306-14 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6
Warnke P, Alamein M, Skabo S, Stephens S, BOURKE R, Heiner P, et al. Primordium of an artificial Bruch's membrane made of nanofibers for engineering of retinal pigment epithelium cell monolayers. Acta Biomater. 2013;9:9414-22 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000
Liu Z, Meyer C, Fimmers R, Stanzel B. Indocyanine green concentrations used in chromovitrectomy cause a reversible functional alteration in the outer blood-retinal barrier. Acta Ophthalmol. 2014;92:e147-55 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:100
Tang E, Xiao X, Mruk D, Qian X, Mok K, Jenardhanan P, et al. Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis. Spermatogenesis. 2012;2:117-126 pubmed
Patel S, Calle Gonzalez B, Paone N, Mueller C, Floss J, Sousa M, et al. Effect of Physiological Oxygen on Primary Human Corneal Endothelial Cell Cultures. Transl Vis Sci Technol. 2022;11:33 pubmed 出版商
Menck K, Heinrichs S, Wlochowitz D, Sitte M, Noeding H, Janshoff A, et al. WNT11/ROR2 signaling is associated with tumor invasion and poor survival in breast cancer. J Exp Clin Cancer Res. 2021;40:395 pubmed 出版商
Miyagishima K, Sharma R, Nimmagadda M, Clore Gronenborn K, Qureshy Z, Ortolan D, et al. AMPK modulation ameliorates dominant disease phenotypes of CTRP5 variant in retinal degeneration. Commun Biol. 2021;4:1360 pubmed 出版商
Lee S, Teng Y, Son M, Ku B, Hwang H, Tergaonkar V, et al. Three-Dimensional Aggregated Spheroid Model of Hepatocellular Carcinoma Using a 96-Pillar/Well Plate. Molecules. 2021;26: pubmed 出版商
Pasquariello R, Verdile N, Pavlovic R, Panseri S, Schirmer K, Brevini T, et al. New Stable Cell Lines Derived from the Proximal and Distal Intestine of Rainbow Trout (Oncorhynchus mykiss) Retain Several Properties Observed In Vivo. Cells. 2021;10: pubmed 出版商
Marquez Curtis L, Bokenfohr R, McGann L, Elliott J. Cryopreservation of human cerebral microvascular endothelial cells and astrocytes in suspension and monolayers. PLoS ONE. 2021;16:e0249814 pubmed 出版商
Schneider S, De Cegli R, Nagarajan J, Kretschmer V, Matthiessen P, Intartaglia D, et al. Loss of Ciliary Gene Bbs8 Results in Physiological Defects in the Retinal Pigment Epithelium. Front Cell Dev Biol. 2021;9:607121 pubmed 出版商
Paoli R, Di Giuseppe D, Badiola Mateos M, Martinelli E, Lopez Martinez M, Samitier J. Rapid Manufacturing of Multilayered Microfluidic Devices for Organ on a Chip Applications. Sensors (Basel). 2021;21: pubmed 出版商
Ryu H, Lee H, Lee J, Noh H, Shin M, Kumar V, et al. The molecular dynamics of subdistal appendages in multi-ciliated cells. Nat Commun. 2021;12:612 pubmed 出版商
Pavelj x161 ek D, Ivi x10d ak Kocjan K, Treven P, Ben x10d ina M, Jerala R, Rogelj I. Distinctive probiotic features share common TLR2-dependent signalling in intestinal epithelial cells. Cell Microbiol. 2021;23:e13264 pubmed 出版商
Huang X, Shi X, Hansen M, Setiady I, Nemeth C, Celli A, et al. Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes. ACS Nano. 2020;14:13192-13202 pubmed 出版商
Fang Y, Lai K, She P, Sun J, Tao W, Zhong T. Tbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion. Front Cell Dev Biol. 2020;8:738 pubmed 出版商
Yu Y, Lu J, Oliphant K, Gupta N, Claud K, Lu L. Maternal administration of probiotics promotes gut development in mouse offsprings. PLoS ONE. 2020;15:e0237182 pubmed 出版商
Kim H, Witt H, Oswald T, Tarantola M. Adhesion of Epithelial Cells to PNIPAm Treated Surfaces for Temperature-Controlled Cell-Sheet Harvesting. ACS Appl Mater Interfaces. 2020;12:33516-33529 pubmed 出版商
Hempt C, Kaiser J, Scholder O, Buerki Thurnherr T, Hofmann H, Rippl A, et al. The impact of synthetic amorphous silica (E 551) on differentiated Caco-2 cells, a model for the human intestinal epithelium. Toxicol In Vitro. 2020;67:104903 pubmed 出版商
Zheng L, Wang J, Xu J, Zhang X, Liu B, Huang L, et al. Magnesium and vitamin C supplementation attenuates steroid-associated osteonecrosis in a rat model. Biomaterials. 2020;238:119828 pubmed 出版商
Lux T, Hu X, Ben Kraiem A, Blum R, Chen J, Rittner H. Regional Differences in Tight Junction Protein Expression in the Blood-DRG Barrier and Their Alterations after Nerve Traumatic Injury in Rats. Int J Mol Sci. 2019;21: pubmed 出版商
Samy K, Levy E, Phong K, Demaree B, Abate A, Desai T. Human intestinal spheroids cultured using Sacrificial Micromolding as a model system for studying drug transport. Sci Rep. 2019;9:9936 pubmed 出版商
Sherman H, Rossi A. A Novel Three-Dimensional Glioma Blood-Brain Barrier Model for High-Throughput Testing of Tumoricidal Capability. Front Oncol. 2019;9:351 pubmed 出版商
Freire R, Ingano L, Serena G, Cetinbaş M, Anselmo A, Sapone A, et al. Human gut derived-organoids provide model to study gluten response and effects of microbiota-derived molecules in celiac disease. Sci Rep. 2019;9:7029 pubmed 出版商
Schneider S, Hotaling N, Campos M, Patnaik S, Bharti K, May Simera H. Generation of an inducible RPE-specific Cre transgenic-mouse line. PLoS ONE. 2018;13:e0207222 pubmed 出版商
Zhang C, Lee H, Shrivastava A, Wang R, McQuiston T, Challberg S, et al. Long-Term In Vitro Expansion of Epithelial Stem Cells Enabled by Pharmacological Inhibition of PAK1-ROCK-Myosin II and TGF-β Signaling. Cell Rep. 2018;25:598-610.e5 pubmed 出版商
Toosi B, El Zawily A, Truitt L, Shannon M, Allonby O, Babu M, et al. EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours. Oncogene. 2018;37:4073-4093 pubmed 出版商
Xu J, Zhang L, Ye Y, Shan Y, Wan C, Wang J, et al. SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding. Structure. 2017;25:1251-1263.e5 pubmed 出版商
Marneros A. NLRP3 inflammasome blockade inhibits VEGF-A-induced age-related macular degeneration. Cell Rep. 2013;4:945-58 pubmed 出版商
Chambrey R, Kurth I, Peti Peterdi J, Houillier P, Purkerson J, Leviel F, et al. Renal intercalated cells are rather energized by a proton than a sodium pump. Proc Natl Acad Sci U S A. 2013;110:7928-33 pubmed 出版商
Mok K, Mruk D, Silvestrini B, Cheng C. rpS6 Regulates blood-testis barrier dynamics by affecting F-actin organization and protein recruitment. Endocrinology. 2012;153:5036-48 pubmed
产品信息
产品类型 :
抗体
产品名称 :
ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor™ 488
目录# :
339188
规格 :
100微克
定价 :
美国490
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
狗, 人类
应用 :
ELISA: 0.1-1.0 µg/mL (unconjugated), Immunocytochemistry: 5 µg/mL, Western Blot: 1-2 µg/mL
物种 :
狗, 人类
克隆 :
ZO1-1A12
抗体亚型 :
IgG1
储存 :
4° C, store in dark
描述 :
ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
免疫原 :
Human recombinant ZO-1 fusion protein encompassing amino acids 334-634
格式 :
液体
应用w/稀释 :
ELISA: 0.1-1.0 µg/mL (unconjugated), Immunocytochemistry: 5 µg/mL, Western Blot: 1-2 µg/mL
别名 :
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国