产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
水闸蛋白5多克隆抗体
目录 :
34-1600
规格 :
100微克
价格 :
美国428
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 国内马
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 100
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 5e
  • 免疫印迹; 小鼠; 图 4f
Peroutka R, Buzza M, Mukhopadhyay S, Johnson T, Driesbaugh K, Antalis T. Testisin/Prss21 deficiency causes increased vascular permeability and a hemorrhagic phenotype during luteal angiogenesis. PLoS ONE. 2020;15:e0234407 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2e, 2h
Li C, Chen W, Wang J, Xia M, Jia Z, Guo C, et al. Nicotinamide riboside rescues angiotensin II-induced cerebral small vessel disease in mice. CNS Neurosci Ther. 2020;26:438-447 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 s3g
Diéguez Hurtado R, Kato K, Giaimo B, Nieminen Kelhä M, Arf H, Ferrante F, et al. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes. Nat Commun. 2019;10:2817 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 3b
Benz F, Wichitnaowarat V, Lehmann M, Germano R, Mihova D, Macas J, et al. Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice. elife. 2019;8: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 表 1
Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 6c
Gautam J, Zhang X, Yao Y. The role of pericytic laminin in blood brain barrier integrity maintenance. Sci Rep. 2016;6:36450 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s2
Adam A, Lowery A, Martino N, Alsaffar H, Vincent P. Src Family Kinases Modulate the Loss of Endothelial Barrier Function in Response to TNF-α: Crosstalk with p38 Signaling. PLoS ONE. 2016;11:e0161975 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:100; 图 2i
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2b
Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Huang L, Stuart C, Takeda K, D Agnillo F, Golding B. Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5. PLoS ONE. 2016;11:e0160875 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Zhang Z, Yan J, Shi H. Role of Hypoxia Inducible Factor 1 in Hyperglycemia-Exacerbated Blood-Brain Barrier Disruption in Ischemic Stroke. Neurobiol Dis. 2016;95:82-92 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:500; 图 s2
Szalay G, Martinecz B, Lénárt N, Kornyei Z, Orsolits B, Judák L, et al. Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke. Nat Commun. 2016;7:11499 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 4
  • 免疫印迹; 人类; 1:500; 图 4
Liu W, Cai H, Lin M, Zhu L, Gao L, Zhong R, et al. MicroRNA-107 prevents amyloid-beta induced blood-brain barrier disruption and endothelial cell dysfunction by targeting Endophilin-1. Exp Cell Res. 2016;343:248-257 pubmed 出版商
  • 免疫组化-石蜡切片; 国内马; 图 5
  • 免疫印迹; 国内马; 1:1000; 图 1
Lee B, Kang H, Lee D, Ahn C, Jeung E. Claudin-1, -2, -4, and -5: comparison of expression levels and distribution in equine tissues. J Vet Sci. 2016;17:445-451 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:400; 图 4
Teng F, Zhu L, Su J, Zhang X, Li N, Nie Z, et al. Neuroprotective Effects of Poly(ADP-ribose)polymerase Inhibitor Olaparib in Transient Cerebral Ischemia. Neurochem Res. 2016;41:1516-26 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 5
Honig G, Mader S, Chen H, Porat A, Ochani M, Wang P, et al. Blood-Brain Barrier Deterioration and Hippocampal Gene Expression in Polymicrobial Sepsis: An Evaluation of Endothelial MyD88 and the Vagus Nerve. PLoS ONE. 2016;11:e0144215 pubmed 出版商
Deissler H, Rehak M, Wolf A. Impairment of the Retinal Endothelial Cell Barrier Induced by Long-Term Treatment with VEGF-A165 No Longer Depends on the Growth Factor's Presence. Biomolecules. 2022;12: pubmed 出版商
Chang J, Greene C, Frudd K, Araujo Dos Santos L, Futter C, Nichols B, et al. Methamphetamine enhances caveolar transport of therapeutic agents across the rodent blood-brain barrier. Cell Rep Med. 2022;3:100497 pubmed 出版商
Dion Albert L, Cadoret A, Doney E, Kaufmann F, Dudek K, Daigle B, et al. Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue. Nat Commun. 2022;13:164 pubmed 出版商
Yu R, Kim N, Li Y, Jeong J, Park S, Zhou B, et al. Vascular Sema3E-Plexin-D1 Signaling Reactivation Promotes Post-stroke Recovery through VEGF Downregulation in Mice. Transl Stroke Res. 2022;13:142-159 pubmed 出版商
Spieth L, Berghoff S, Stumpf S, Winchenbach J, Michaelis T, Watanabe T, et al. Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport. Neurooncol Adv. 2021;3:vdab140 pubmed 出版商
Wang C, Dong J, Sun J, Huang S, Wu F, Zhang X, et al. Silencing of lncRNA XIST impairs angiogenesis and exacerbates cerebral vascular injury after ischemic stroke. Mol Ther Nucleic Acids. 2021;26:148-160 pubmed 出版商
Wei X, Meel M, Breur M, Bugiani M, Hulleman E, Phoenix T. Defining tumor-associated vascular heterogeneity in pediatric high-grade and diffuse midline gliomas. Acta Neuropathol Commun. 2021;9:142 pubmed 出版商
Torices S, Cabrera R, Stangis M, Naranjo O, Fattakhov N, Téglás T, et al. Expression of SARS-CoV-2-related receptors in cells of the neurovascular unit: implications for HIV-1 infection. J Neuroinflammation. 2021;18:167 pubmed 出版商
Zarkada G, Howard J, Xiao X, Park H, Bizou M, Leclerc S, et al. Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation. Dev Cell. 2021;56:2237-2251.e6 pubmed 出版商
Storck S, Kurtyka M, Pietrzik C. Brain endothelial LRP1 maintains blood-brain barrier integrity. Fluids Barriers CNS. 2021;18:27 pubmed 出版商
Tabariès S, Annis M, Lazaris A, Petrillo S, Huxham J, Abdellatif A, et al. Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern. Commun Biol. 2021;4:657 pubmed 出版商
Nanou A, Bourbouli M, Vetrano S, Schaeper U, Ley S, Kollias G. Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis. Cell Rep. 2021;35:109168 pubmed 出版商
Khan A, Ni W, Lopez Giraldez F, Kluger M, Pober J, Pierce R. Tumor necrosis factor-induced ArhGEF10 selectively activates RhoB contributing to human microvascular endothelial cell tight junction disruption. FASEB J. 2021;35:e21627 pubmed 出版商
Desmarais F, Hervé V, Bergeron K, Ravaut G, Perrotte M, Fyfe Desmarais G, et al. Cerebral Apolipoprotein D Exits the Brain and Accumulates in Peripheral Tissues. Int J Mol Sci. 2021;22: pubmed 出版商
Manian K, Galloway C, Dalvi S, Emanuel A, Mereness J, Black W, et al. 3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration. Cell Stem Cell. 2021;28:846-862.e8 pubmed 出版商
Zhou Q, Vega Leonel J, Santoso M, Wilson C, van den Berg N, Chan C, et al. Molecular imaging of a fluorescent antibody against epidermal growth factor receptor detects high-grade glioma. Sci Rep. 2021;11:5710 pubmed 出版商
Yang P, Tian H, Zou Y, Chambon P, Ichinose H, Honig G, et al. Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis. Front Immunol. 2021;12:616583 pubmed 出版商
Maier Begandt D, Comstra H, Molina S, Krüger N, Ruddiman C, Chen Y, et al. A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability. Sci Signal. 2021;14: pubmed 出版商
Uzunallı G, Herr S, Dieterly A, Shi R, Lyle L. Structural disruption of the blood-brain barrier in repetitive primary blast injury. Fluids Barriers CNS. 2021;18:2 pubmed 出版商
Koh S, Ooi S, Lui N, Qiong C, Ho L, Cheah I, et al. Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury. Neuromolecular Med. 2021;23:184-198 pubmed 出版商
Hollier P, Chapouly C, Diop A, Guimbal S, Cornuault L, Gadeau A, et al. Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability. Cardiovasc Res. 2021;117:2489-2501 pubmed 出版商
Nagatake T, Zhao Y, Ito T, Itoh M, Kometani K, Furuse M, et al. Selective expression of claudin-5 in thymic endothelial cells regulates the blood-thymus barrier and T-cell export. Int Immunol. 2021;33:171-182 pubmed 出版商
Vion A, Perovic T, Petit C, Hollfinger I, Bartels Klein E, Frampton E, et al. Endothelial Cell Orientation and Polarity Are Controlled by Shear Stress and VEGF Through Distinct Signaling Pathways. Front Physiol. 2020;11:623769 pubmed 出版商
Burek M, Burmester S, Salvador E, Moller Ehrlich K, Schneider R, Roewer N, et al. Kidney Ischemia/Reperfusion Injury Induces Changes in the Drug Transporter Expression at the Blood-Brain Barrier in vivo and in vitro. Front Physiol. 2020;11:569881 pubmed 出版商
Greene C, Hanley N, Campbell M. Blood-brain barrier associated tight junction disruption is a hallmark feature of major psychiatric disorders. Transl Psychiatry. 2020;10:373 pubmed 出版商
Pellegrini L, Albecka A, Mallery D, Kellner M, Paul D, Carter A, et al. SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids. Cell Stem Cell. 2020;27:951-961.e5 pubmed 出版商
Frye M, Stritt S, Ortsäter H, Hernandez Vasquez M, Kaakinen M, Vicente A, et al. EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity. elife. 2020;9: pubmed 出版商
Duarte Lobo D, Nobre R, Oliveira Miranda C, Pereira D, Castelhano J, Sereno J, et al. The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples. Acta Neuropathol Commun. 2020;8:152 pubmed 出版商
Brunner N, Stein L, Cornelius V, Knittel R, Fallier Becker P, Amasheh S. Blood-Brain Barrier Protein Claudin-5 Expressed in Paired Xenopus laevis Oocytes Mediates Cell-Cell Interaction. Front Physiol. 2020;11:857 pubmed 出版商
Clé M, Desmetz C, Barthelemy J, Martin M, Constant O, Maarifi G, et al. Zika Virus Infection Promotes Local Inflammation, Cell Adhesion Molecule Upregulation, and Leukocyte Recruitment at the Blood-Brain Barrier. MBio. 2020;11: pubmed 出版商
Spampinato S, Merlo S, Fagone E, Fruciano M, Sano Y, Kanda T, et al. Reciprocal Interplay Between Astrocytes and CD4+ Cells Affects Blood-Brain Barrier and Neuronal Function in Response to β Amyloid. Front Mol Neurosci. 2020;13:120 pubmed 出版商
Markov A, Fedorova A, Kravtsova V, Bikmurzina A, Okorokova L, Matchkov V, et al. Circulating Ouabain Modulates Expression of Claudins in Rat Intestine and Cerebral Blood Vessels. Int J Mol Sci. 2020;21: pubmed 出版商
Jäckle A, Ziemssen F, Kuhn E, Kampmeier J, Lang G, Lang G, et al. Sitagliptin and the Blood-Retina Barrier: Effects on Retinal Endothelial Cells Manifested Only after Prolonged Exposure. J Diabetes Res. 2020;2020:2450781 pubmed 出版商
Geng X, Yanagida K, Akwii R, Choi D, Chen L, Ho Y, et al. S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020;5: pubmed 出版商
Deligne C, Hachani J, Duban Deweer S, Meignan S, Leblond P, Carcaboso A, et al. Development of a human in vitro blood-brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance. Fluids Barriers CNS. 2020;17:37 pubmed 出版商
Zhang X, Wang L, Han Z, Dong J, Pang D, Fu Y, et al. KLF4 alleviates cerebral vascular injury by ameliorating vascular endothelial inflammation and regulating tight junction protein expression following ischemic stroke. J Neuroinflammation. 2020;17:107 pubmed 出版商
Roudnicky F, Kim B, Lan Y, Schmucki R, Küppers V, Christensen K, et al. Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance. Sci Rep. 2020;10:3886 pubmed 出版商
Díaz Coránguez M, Lin C, Liebner S, Antonetti D. Norrin restores blood-retinal barrier properties after vascular endothelial growth factor-induced permeability. J Biol Chem. 2020;295:4647-4660 pubmed 出版商
Chow B, Nuñez V, Kaplan L, Granger A, Bistrong K, Zucker H, et al. Caveolae in CNS arterioles mediate neurovascular coupling. Nature. 2020;579:106-110 pubmed 出版商
He Q, Liu H, Huang C, Wang R, Luo M, Lu W. Herpes Simplex Virus 1-Induced Blood-Brain Barrier Damage Involves Apoptosis Associated With GM130-Mediated Golgi Stress. Front Mol Neurosci. 2020;13:2 pubmed 出版商
Xu B, Kurachi M, Shimauchi Ohtaki H, Yoshimoto Y, Ishizaki Y. Transplantation of iPS-derived vascular endothelial cells improves white matter ischemic damage. J Neurochem. 2020;153:759-771 pubmed 出版商
Park H, Yamamoto H, Mohn L, Ambühl L, Kanai K, Schmidt I, et al. Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy. Nat Commun. 2019;10:5243 pubmed 出版商
Munji R, Soung A, Weiner G, Sohet F, Semple B, Trivedi A, et al. Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module. Nat Neurosci. 2019;22:1892-1902 pubmed 出版商
Mahamud M, Geng X, Ho Y, Cha B, Kim Y, Ma J, et al. GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019;146: pubmed 出版商
Nakamura K, Ikeuchi T, Nara K, Rhodes C, Zhang P, Chiba Y, et al. Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier. J Cell Biol. 2019;218:3506-3525 pubmed 出版商
Castro Dias M, Coisne C, Baden P, Enzmann G, Garrett L, Becker L, et al. Claudin-12 is not required for blood-brain barrier tight junction function. Fluids Barriers CNS. 2019;16:30 pubmed 出版商
Spampinato S, Merlo S, Fagone E, Fruciano M, Barbagallo C, Kanda T, et al. Astrocytes Modify Migration of PBMCs Induced by β-Amyloid in a Blood-Brain Barrier in vitro Model. Front Cell Neurosci. 2019;13:337 pubmed 出版商
Hudson N, Celkova L, Hopkins A, Greene C, Storti F, Ozaki E, et al. Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy. JCI Insight. 2019;4: pubmed 出版商
Jensen L, Hot B, Ramsköld D, Germano R, Yokota C, Giatrellis S, et al. Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of β-Catenin Signaling. Arterioscler Thromb Vasc Biol. 2019;39:1432-1447 pubmed 出版商
Weiner G, Shah S, Angelopoulos C, Bartakova A, Pulido R, Murphy A, et al. Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation. Nat Commun. 2019;10:2477 pubmed 出版商
Chen S, Lin M, Tsai J, He P, Luo W, Herschman H, et al. EP4 Antagonist-Elicited Extracellular Vesicles from Mesenchymal Stem Cells Rescue Cognition/Learning Deficiencies by Restoring Brain Cellular Functions. Stem Cells Transl Med. 2019;8:707-723 pubmed 出版商
Griemert E, Schwarzmaier S, Hummel R, Gölz C, Yang D, Neuhaus W, et al. Plasminogen activator inhibitor-1 augments damage by impairing fibrinolysis after traumatic brain injury. Ann Neurol. 2019;85:667-680 pubmed 出版商
Corem N, Anzi S, Gelb S, Ben Zvi A. Leptin receptor deficiency induces early, transient and hyperglycaemia-independent blood-brain barrier dysfunction. Sci Rep. 2019;9:2884 pubmed 出版商
Zhu L, Lin M, Ma J, Liu W, Gao L, Wei S, et al. The role of LINC00094/miR-224-5p (miR-497-5p)/Endophilin-1 axis in Memantine mediated protective effects on blood-brain barrier in AD microenvironment. J Cell Mol Med. 2019;23:3280-3292 pubmed 出版商
Yang T, Xu G, Newton P, Chagin A, Mkrtchian S, Carlström M, et al. Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders. Br J Anaesth. 2019;122:350-360 pubmed 出版商
Hsieh J, Rathore A, Soundarajan G, St John A. Japanese encephalitis virus neuropenetrance is driven by mast cell chymase. Nat Commun. 2019;10:706 pubmed 出版商
van der Wijk A, Wisniewska Kruk J, Vogels I, van Veen H, Ip W, van der Wel N, et al. Expression patterns of endothelial permeability pathways in the development of the blood-retinal barrier in mice. FASEB J. 2019;33:5320-5333 pubmed 出版商
Bieber M, Schuhmann M, Volz J, Kumar G, Vaidya J, Nieswandt B, et al. Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function. Stroke. 2019;50:478-486 pubmed 出版商
Deissler H, Lang G, Lang G. Fate of the Fc fusion protein aflibercept in retinal endothelial cells: competition of recycling and degradation. Graefes Arch Clin Exp Ophthalmol. 2019;257:83-94 pubmed 出版商
Feng S, Zou L, Wang H, He R, Liu K, Zhu H. RhoA/ROCK-2 Pathway Inhibition and Tight Junction Protein Upregulation by Catalpol Suppresses Lipopolysaccaride-Induced Disruption of Blood-Brain Barrier Permeability. Molecules. 2018;23: pubmed 出版商
Che Y, Geng B, Xu Y, Miao X, Chen L, Mu X, et al. Helicobacter pylori-induced exosomal MET educates tumour-associated macrophages to promote gastric cancer progression. J Cell Mol Med. 2018;22:5708-5719 pubmed 出版商
Honkura N, Richards M, Laviña B, Sáinz Jaspeado M, Betsholtz C, Claesson Welsh L. Intravital imaging-based analysis tools for vessel identification and assessment of concurrent dynamic vascular events. Nat Commun. 2018;9:2746 pubmed 出版商
Dong C, Helton E, Zhou P, Ouyang X, d Anglemont de Tassigny X, Pascual A, et al. Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neuropathy. Tissue Barriers. 2018;6:1-22 pubmed 出版商
Hollenbach J, Jung K, Noelke J, Gasse H, Pfarrer C, Koy M, et al. Loss of connexin43 in murine Sertoli cells and its effect on blood-testis barrier formation and dynamics. PLoS ONE. 2018;13:e0198100 pubmed 出版商
Koo Y, Hawkins B, Yun Y. Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screening. Sci Rep. 2018;8:2841 pubmed 出版商
Lopez Ramirez M, Fonseca G, Zeineddine H, Girard R, Moore T, Pham A, et al. Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations. J Exp Med. 2017;214:3331-3346 pubmed 出版商
Mohamed R, Sharma I, Ibrahim A, Saleh H, Elsherbiny N, Fulzele S, et al. Hyperhomocysteinemia Alters Retinal Endothelial Cells Barrier Function and Angiogenic Potential via Activation of Oxidative Stress. Sci Rep. 2017;7:11952 pubmed 出版商
Izawa Y, Gu Y, Osada T, Kanazawa M, Hawkins B, Koziol J, et al. β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability. J Cereb Blood Flow Metab. 2018;38:641-658 pubmed 出版商
Sauer R, Kirchner J, Yang S, Hu L, Leinders M, Sommer C, et al. Blood-spinal cord barrier breakdown and pericyte deficiency in peripheral neuropathy. Ann N Y Acad Sci. 2017;1405:71-88 pubmed 出版商
Song Y, Du D, Li L, Xu J, Dutta P, Lin Y. In Vitro Study of Receptor-Mediated Silica Nanoparticles Delivery across Blood-Brain Barrier. ACS Appl Mater Interfaces. 2017;9:20410-20416 pubmed 出版商
Dithmer S, Staat C, Müller C, Ku M, Pohlmann A, Niendorf T, et al. Claudin peptidomimetics modulate tissue barriers for enhanced drug delivery. Ann N Y Acad Sci. 2017;1397:169-184 pubmed 出版商
Spampinato S, Merlo S, Sano Y, Kanda T, Sortino M. Astrocytes contribute to Aβ-induced blood-brain barrier damage through activation of endothelial MMP9. J Neurochem. 2017;142:464-477 pubmed 出版商
Leclercq S, Mian F, Stanisz A, Bindels L, Cambier E, Ben Amram H, et al. Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior. Nat Commun. 2017;8:15062 pubmed 出版商
Chang J, Mancuso M, Maier C, Liang X, Yuki K, Yang L, et al. Gpr124 is essential for blood-brain barrier integrity in central nervous system disease. Nat Med. 2017;23:450-460 pubmed 出版商
Cieniewicz A, Kirchner T, Hinke S, Nanjunda R, D AQUINO K, Boayke K, et al. Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance. Diabetes. 2017;66:206-217 pubmed 出版商
Neuhaus W, Schlundt M, Fehrholz M, Ehrke A, Kunzmann S, Liebner S, et al. Multiple Antenatal Dexamethasone Treatment Alters Brain Vessel Differentiation in Newborn Mouse Pups. PLoS ONE. 2015;10:e0136221 pubmed 出版商
Meadows S, Cleaver O. Annexin A3 Regulates Early Blood Vessel Formation. PLoS ONE. 2015;10:e0132580 pubmed 出版商
Cai H, Xue Y, Wang P, Wang Z, Li Z, Hu Y, et al. The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144. Oncotarget. 2015;6:19759-79 pubmed
Staat C, Coisne C, Dabrowski S, Stamatovic S, Andjelkovic A, Wolburg H, et al. Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers. Biomaterials. 2015;54:9-20 pubmed 出版商
Ward C, Schlingmann B, Stecenko A, Guidot D, Koval M. NF-κB inhibitors impair lung epithelial tight junctions in the absence of inflammation. Tissue Barriers. 2015;3:e982424 pubmed 出版商
Clark P, Kim R, Pober J, Kluger M. Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases. PLoS ONE. 2015;10:e0120075 pubmed 出版商
Boulay A, Mazeraud A, Cisternino S, Saubaméa B, Mailly P, Jourdren L, et al. Immune quiescence of the brain is set by astroglial connexin 43. J Neurosci. 2015;35:4427-39 pubmed 出版商
Sohet F, Lin C, Munji R, Lee S, Ruderisch N, Soung A, et al. LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. J Cell Biol. 2015;208:703-11 pubmed 出版商
Licht T, Dor Wollman T, Ben Zvi A, Rothe G, Keshet E. Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity. J Clin Invest. 2015;125:1319-28 pubmed 出版商
Cai H, Liu W, Xue Y, Shang X, Liu J, Li Z, et al. Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression. J Neuropathol Exp Neurol. 2015;74:25-37 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
水闸蛋白5多克隆抗体
目录# :
34-1600
规格 :
100微克
价格 :
美国428
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类, 小鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
免疫原 :
Synthetic peptide derived from the C-terminal region of mouse Claudin-5
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Western Blot: Assay-dependent
别名 :
AI854493; AWAL; BEC1; Brain endothelial cell clone 1 protein; claudin 5; claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); claudin-5; claudin-5 protein; Cldn5; CPETRL1; lung-specific membrane protein; MBEC1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; Unknown (protein for MGC:138054)
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国