产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CREB单克隆抗体(LB 9)
目录 :
35-0900
规格 :
100µg
价格 :
美国345.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
LB 9
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 5
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Oliveira D, Sanada P, Filho A, Conceição G, Cerutti J, Cerutti S. Long-term treatment with standardized extract of Ginkgo biloba L. enhances the conditioned suppression of licking in rats by the modulation of neuronal and glial cell function in the dorsal hippocampus and central amygdala. Neuroscience. 2013;235:70-86 pubmed 出版商
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| Engelking L, Liang G, Hammer R, Takaishi K, Kuriyama H, Evers B, et al. Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins. J Clin Invest. 2005;115:2489-98 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CREB单克隆抗体(LB 9)
目录# :
35-0900
规格 :
100µg
价格 :
美国345.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
ELISA: Assay Dependent, Immunocytochemistry: 1-3 µg/mL, Immunofluorescence: 1-3 µg/mL, Immunohistochemistry: Assay Dependent, Western Blot: 1-3 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
LB 9
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
CREB (Cyclic AMP response element binding protein) is a 43 kDa basic/leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation of CREB occurs via p44/42 MAP kinase and p90RSK, and via p38 MAP kinase and MSK1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB is involved in different cellular processes including the synchronization of circadian rhythmicity, differentiation of adipose cells, and learning and memory. In humans, the gene is located on the q arm of chromosome 2. Diseases associated with CREB dysfunction include Alzheimer’s Disease, histiocytoma and soft tissue melanoma.
免疫原 :
重组人类CREB-A蛋白
格式 :
液体
应用w/稀释 :
ELISA: Assay Dependent, Immunocytochemistry: 1-3 µg/mL, Immunofluorescence: 1-3 µg/mL, Immunohistochemistry: Assay Dependent, Western Blot: 1-3 µg/mL
别名 :
2310001E10Rik; 3526402H21Rik; active transcription factor CREB; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; Creb; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; Cyclic AMP-responsive element-binding protein 1; htCREB; MGC9284; OTTHUMP00000206661; OTTHUMP00000206662; OTTHUMP00000206667; transactivator protein; Y protein
更多信息或购买 :
公司信息
赛默飞世尔