产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3单克隆抗体(4-1-18)
目录 :
35-1600Z
规格 :
100µg
价格 :
425.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4-1-18
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 7
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:100; 表 3
Frohwitter G, Buerger H, van Diest P, Korsching E, Kleinheinz J, Fillies T. Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways. Oncol Lett. 2016;12:107-113 pubmed
  • 免疫印迹; 人类; 2 ug/ml
Cuevas M, Lindeman T. In vitro cytotoxicity of 4'-OH-tamoxifen and estradiol in human endometrial adenocarcinoma cells HEC-1A and HEC-1B. Oncol Rep. 2015;33:464-70 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:20; 图 4
Pacheco Tovar D, López Luna A, Herrera Esparza R, Avalos Diaz E. The caspase pathway as a possible therapeutic target in experimental pemphigus. Autoimmune Dis. 2011;2011:563091 pubmed 出版商
Frohwitter G, Buerger H, Korsching E, van Diest P, Kleinheinz J, Fillies T. Site-specific gene expression patterns in oral cancer. Head Face Med. 2017;13:6 pubmed 出版商
Fodor R, Georgescu A, Grigorescu B, Cioc A, Veres M, Cotoi O, et al. Caspase 3 expression and plasma level of Fas ligand as apoptosis biomarkers in inflammatory endotoxemic lung injury. Rom J Morphol Embryol. 2016;57:951-957 pubmed
Chung Y, Lin C, Chou C, Hsu C. The effect of Longan seed polyphenols on colorectal carcinoma cells. Eur J Clin Invest. 2010;40:713-21 pubmed 出版商
Hsu C, Lin Y, Chou C, Zhou S, Hsu Y, Liu C, et al. Mechanisms of grape seed procyanidin-induced apoptosis in colorectal carcinoma cells. Anticancer Res. 2009;29:283-9 pubmed
产品信息
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3单克隆抗体(4-1-18)
目录# :
35-1600Z
规格 :
100µg
价格(美元) :
425.00美元
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunohistochemistry: 1-2 µg/mL, Western Blot: 1-2 µg/mL
物种 :
人类
克隆 :
4-1-18
抗体亚型 :
IgG2a
储存 :
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
描述 :
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
免疫原 :
全长, 重组人类胱氨酸-天冬氨酸蛋白酶3蛋白
格式 :
液体
应用w/稀释 :
Immunohistochemistry: 1-2 µg/mL, Western Blot: 1-2 µg/mL
别名 :
A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; Protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国