产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3单克隆抗体(4-1-18)
目录 :
35-1600Z
规格 :
100微克
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4-1-18
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 7
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
| Frohwitter G, Buerger H, van Diest P, Korsching E, Kleinheinz J, Fillies T. Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways. Oncol Lett. 2016;12:107-113 pubmed
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Fodor R, Georgescu A, Grigorescu B, Cioc A, Veres M, Cotoi O, et al. Caspase 3 expression and plasma level of Fas ligand as apoptosis biomarkers in inflammatory endotoxemic lung injury. Rom J Morphol Embryol. 2016;57:951-957 pubmed
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Hsu C, Lin Y, Chou C, Zhou S, Hsu Y, Liu C, et al. Mechanisms of grape seed procyanidin-induced apoptosis in colorectal carcinoma cells. Anticancer Res. 2009;29:283-9 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3单克隆抗体(4-1-18)
目录# :
35-1600Z
规格 :
100微克
价格 :
美国425.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Immunohistochemistry: 1-2 µg/mL, Western Blot: 1-2 µg/mL
物种 :
人类
克隆 :
4-1-18
抗体亚型 :
IgG2a
储存 :
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
描述 :
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
免疫原 :
全长, 重组人类胱氨酸-天冬氨酸蛋白酶3蛋白
格式 :
液体
应用w/稀释 :
Immunohistochemistry: 1-2 µg/mL, Western Blot: 1-2 µg/mL
别名 :
A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
更多信息或购买 :
公司信息
赛默飞世尔