产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
VEGF Receptor 1 (soluble) Polyclonal Antibody
目录 :
36-1100
规格 :
100微克
价格 :
美国375.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 3
参考文献
Zsengellér Z, Lo A, Tavasoli M, Pernicone E, Karumanchi S, Rosen S. Soluble fms-Like Tyrosine Kinase 1 Localization in Renal Biopsies of CKD. Kidney Int Rep. 2019;4:1735-1741 pubmed 出版商
Capossela S, Bertolo A, Gunasekera K, Pötzel T, Baur M, Stoyanov J. VEGF vascularization pathway in human intervertebral disc does not change during the disc degeneration process. BMC Res Notes. 2018;11:333 pubmed 出版商
He W, Bai G, Zhou H, Wei N, White N, Lauer J, et al. CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase. Nature. 2015;526:710-4 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
VEGF Receptor 1 (soluble) Polyclonal Antibody
目录# :
36-1100
规格 :
100微克
价格 :
美国375.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类
应用 :
ELISA: Assay-dependent, Western Blot: Assay-dependent
物种 :
人类
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.
免疫原 :
Synthetic peptide derived from the C-terminal region of the soluble form of the human VEGF Receptor-1 (sVEGFR-1, sFlt-1) protein.
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Western Blot: Assay-dependent
别名 :
AI323757; embryonic receptor kinase 2; Emrk2; FLT; FLT1; FLT-1; fms related tyrosine kinase 1; FMS-like tyrosine kinase 1; FMS-related tyrosine kinase 1; Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FRT; i21; sFlt1; soluble VEGFR 1; sVEGFR 1; Tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; Vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor-1; vascular permeability factor receptor; VEGF R1; VEGFR1; VEGFR-1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国