产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Nogo-A Polyclonal Antibody
目录 :
36-6600
规格 :
100微克
价格 :
美国399.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
大鼠
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
Nogo-A Polyclonal Antibody
目录# :
36-6600
规格 :
100微克
价格 :
美国399.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
大鼠
应用 :
Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
物种 :
大鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases. Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE. NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor. It is highly expressed in oligodendrocytes in the white matter of the CNS, blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models. NogoA has also been suggested to play a role in neurodegenerative diseases such as Amyotrophic lateral sclerosis, in which case NogoA is found at elevated levels in postmortem muscular samples, and multiple sclerosis (MS), in which case autoantibodies to NogoA have been found in serum and cerebrospinal fluid in MS patients.
免疫原 :
Synthetic peptide derived from the internal region of rat Nogo-A (Reticulon 4-A, Foocen, Glut4 Vesicle 20kDa Protein), which differs from the human sequence by only one amino acid.
格式 :
液体
应用w/稀释 :
Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
别名 :
1110020G17Rik; AA407876; AA409940; AA960376; ASY; C130026I10Rik; Foocen; glut4 vesicle 20 kDa protein; GLUT4 vesicle 20kDa protein; Human NogoA; KIAA0886; mKIAA0886; mKIAA4153; My043; My043 protein; Nbla00271; Nbla10545; neurite growth inhibitor 220; neurite outgrowth inhibitor; Neuroendocrine-specific protein; Neuroendocrine-specific protein C homolog; NgA; NI220/250; NI-220/250; NI-250; Nogo; Nogo protein; Nogo-A; Nogo-B; NOGOC; Nogo-C; NSP; NSP-CL; r; rat N; rat NogoA; reticulon 4; reticulon 5; reticulon-4; Reticulon-5; RTN4; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C; RTN-x; SP1507; Vp20
更多信息或购买 :
公司信息
赛默飞世尔