产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化酪氨酸羟化酶(Ser40)多克隆抗体
目录 :
36-8600
规格 :
100微升
价格 :
美国425.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-自由浮动切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 3
出版应用/物种/样本/稀释参考文献
  • 免疫组化-自由浮动切片; 大鼠; 1:25,000; 图 7
Aquino N, Araujo Lopes R, Batista I, Henriques P, Poletini M, Franci C, et al. Hypothalamic Effects of Tamoxifen on Oestrogen Regulation of Luteinising Hormone and Prolactin Secretion in Female Rats. J Neuroendocrinol. 2016;28: pubmed 出版商
Yip S, Romano N, Gustafson P, Hodson D, Williams E, Kokay I, et al. Elevated Prolactin during Pregnancy Drives a Phenotypic Switch in Mouse Hypothalamic Dopaminergic Neurons. Cell Rep. 2019;26:1787-1799.e5 pubmed 出版商
Portella A, Silveira P, Laureano D, Cardoso S, Bittencourt V, Noschang C, et al. Litter size reduction alters insulin signaling in the ventral tegmental area and influences dopamine-related behaviors in adult rats. Behav Brain Res. 2015;278:66-73 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
磷酸化酪氨酸羟化酶(Ser40)多克隆抗体
目录# :
36-8600
规格 :
100微升
价格 :
美国425.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
大鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 1:1,000, Immunohistochemistry: 1:1,000, Western Blot: 1:1,000
物种 :
大鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine. In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4). BH4 binds to the TH catalytic domain, resulting in enzymatic activity. Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated. These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains. TH is also responsible for the conversion of L-tyrosine to L-dopa. TH plays a key role in the physiology of adrenergic neurons. The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.
免疫原 :
Synthetic phospho-peptide derived from the rat tyrosine hydroxylase (TH) protein
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 1:1,000, Immunohistochemistry: 1:1,000, Western Blot: 1:1,000
别名 :
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国