产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
HuR Monoclonal Antibody (3A2)
目录 :
39-0600
规格 :
100微克
价格 :
美国500.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3A2
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 核糖核酸免疫沉淀
更多信息或购买 :
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Weng K, Hung C, Hsieh P, Li M, Chen G, Kung Y, et al. A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells. Nucleic Acids Res. 2014;42:12789-805 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2
Walker A, Soo K, Sundaramoorthy V, Parakh S, Ma Y, Farg M, et al. ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation. PLoS ONE. 2013;8:e81170 pubmed 出版商
  • 免疫组化; 人类
Hackman P, Sarparanta J, Lehtinen S, Vihola A, Evilä A, Jonson P, et al. Welander distal myopathy is caused by a mutation in the RNA-binding protein TIA1. Ann Neurol. 2013;73:500-9 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
  • 免疫印迹; 人类; 图 2
Markus M, Marques F, Morris B. Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAs. PLoS ONE. 2011;6:e28926 pubmed 出版商
  • 免疫沉淀; 人类; 图 2
  • 免疫印迹; 人类; 图 2
Chock K, Allison J, ElShamy W. BRCA1-IRIS overexpression abrogates UV-induced p38MAPK/p53 and promotes proliferation of damaged cells. Oncogene. 2010;29:5274-85 pubmed 出版商
Shi B, Zhang J, Heng J, Gong J, Zhang T, Li P, et al. RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function. Genome Biol. 2020;21:120 pubmed 出版商
Dai P, Wang X, Gou L, Li Z, Wen Z, Chen Z, et al. A Translation-Activating Function of MIWI/piRNA during Mouse Spermiogenesis. Cell. 2019;179:1566-1581.e16 pubmed 出版商
Dhir T, Schultz C, Jain A, Brown S, Haber A, Goetz A, et al. Abemaciclib Is Effective Against Pancreatic Cancer Cells and Synergizes with HuR and YAP1 Inhibition. Mol Cancer Res. 2019;17:2029-2041 pubmed 出版商
Zagore L, Sweet T, Hannigan M, Weyn Vanhentenryck S, Jobava R, Hatzoglou M, et al. DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions. Cell Rep. 2018;25:1225-1240.e6 pubmed 出版商
Soo K, Sultana J, King A, Atkinson R, Warraich S, Sundaramoorthy V, et al. ALS-associated mutant FUS inhibits macroautophagy which is restored by overexpression of Rab1. Cell Death Discov. 2015;1:15030 pubmed 出版商
Kim G, Lim S, Kim Y. Expression of HuR, COX-2, and survivin in lung cancers; cytoplasmic HuR stabilizes cyclooxygenase-2 in squamous cell carcinomas. Mod Pathol. 2011;24:1336-47 pubmed 出版商
Tiruchinapalli D, Caron M, Keene J. Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain. J Neurochem. 2008;107:1529-43 pubmed 出版商
Denkert C, Weichert W, Pest S, Koch I, Licht D, Köbel M, et al. Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expression. Cancer Res. 2004;64:189-95 pubmed
Gallouzi I, Brennan C, Stenberg M, Swanson M, Eversole A, Maizels N, et al. HuR binding to cytoplasmic mRNA is perturbed by heat shock. Proc Natl Acad Sci U S A. 2000;97:3073-8 pubmed
产品信息
产品类型 :
抗体
产品名称 :
HuR Monoclonal Antibody (3A2)
目录# :
39-0600
规格 :
100微克
价格 :
美国500.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry: Assay-dependent, RNA Immunoprecipitation: 5 µL/10^6 ceLLs, Western Blot: 1-3 µg/mL
物种 :
人类
克隆 :
3A2
抗体亚型 :
IgG1, kappa
储存 :
-20°C
描述 :
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
免疫原 :
Recombinant human HuR protein
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry: Assay-dependent, RNA Immunoprecipitation: 5 µL/10^6 ceLLs, Western Blot: 1-3 µg/mL
别名 :
2410055N02Rik; ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV like 1; ELAV like RNA binding protein 1; ELAV like RNA binding protein 1a; ELAV1; Elavl1; elavl1 protein; elavl1a; elav-like generic protein; ELAV-like protein 1; ELAV-like protein 1; ELAV-like protein 1a; elav-related A; Elra; embryonic lethal, abnormal vision, drosophila, homolog-like 1; embryonic lethal, abnormal vision-related A; etID309757.2; fa25f08; fb59a02; fc60g02; Hu antigen R; Hua; HU-antigen A; hu-antigen R; Human antigen R; HuR; melG; ribonucleoprotein; W91709; wu:fa25f08; wu:fb59a02; wu:fc60g02; zHuA
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国