产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
蛋白
产品名称 :
Human IL-29 (IFN lambda 1) ELISA Standard Recombinant Protein, eBioscience™
目录 :
39-8299-65
规格 :
4 pack
价格 :
115.00美元
更多信息或购买 :
产品信息
产品类型 :
蛋白
产品名称 :
Human IL-29 (IFN lambda 1) ELISA Standard Recombinant Protein, eBioscience™
目录# :
39-8299-65
规格 :
4 pack
价格(美元) :
115.00美元
克隆性 :
重组
纯度 :
亲和色谱
宿主 :
大肠杆菌
反应物种 :
人类
应用 :
Control: Assay-Dependent, ELISA: Assay-Dependent
物种 :
人类
储存 :
-80°C
描述 :
IFN-lambdas constitute a novel family of interferons that mediate the induction of anti-viral protection in a wide variety of cells. There are three members in this family, namely lambda1, lambda2, and lambda3, which are also known as IL-29, IL-28A, and IL-28B, respectively. Similar to type I IFNs, IFN-lambdas activate an intracellular signaling to promote gene expression. IFN-lambdas mediate their anti-viral protection through a class II cytokine receptor complex composed of two essential receptor proteins, CRF2-12/IFN-lambdaR1, which is unique to IFN-lambdas, and CFR2-4/IL-10R2, which is shared with IL-10, IL-22, and IL-26 receptors. The IFN-lambdas, IL-28 and IL-29, have recently been reported to prime dendritic cells to induce proliferation of Foxp3-bearing regulatory T cells. DCs that differentiate in response to IFN-lambdas express high levels of class I and II MHC gene products, but low levels of costimulatory molecules. Moreover, these cells can specifically induce IL-2-dependent proliferation of CD4+CD25+FOXP3+ T cells with contact-dependent suppressive activity.
格式 :
液体
应用w/稀释 :
Control: Assay-Dependent, ELISA: Assay-Dependent
别名 :
Cytokine Zcyto21; FNL1; IFN lambda1; IFNL1; IFN-lambda-1; IL29; IL-29; ILN; interferon lambda 1; Interferon lambda1; interferon lambda-1; interferon, lambda 1; interferon-lambda-1; Interleukin; interleukin 29 (interferon, lambda 1); interleukin-29; ZCYTO21
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国