NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

Cullin 5 Monoclonal Antibody (ZC009)

39-9000

100微克

美国398.00

单克隆

小鼠

未共轭

ZC009

人类, 小鼠, 大鼠

免疫印迹, 酶联免疫吸附测定

Cullin 5 Monoclonal Antibody (ZC009)

39-9000

100微克

美国398.00

单克隆

蛋白质A

小鼠

人类, 小鼠, 大鼠

ELISA: Assay-dependent, Western Blot: 1-2 µg/mL

人类, 小鼠, 大鼠

ZC009

IgG1, kappa

-20°C

CUL5 is a core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. It seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein and may form a cell surface vasopressin receptor.

Synthetic peptide derived from the N-terminal region of the mouse and rat CUL-5/VACM-1 proteins, which are 89% homologous to human

液体

ELISA: Assay-dependent, Western Blot: 1-2 µg/mL

4921514I20Rik; 8430423K24Rik; AI852817; C030032G03Rik; C330021I08Rik; CUL5; CUL-5; cullin 5; cullin-5; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1); Vacm1; VACM-1; vasopressin-activated calcium-mobilizing receptor 1; vasopressin-activated calcium-mobilizing receptor protein; Vasopressin-activated calcium-mobilizing receptor-1