产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
SPRY1多克隆抗体
目录 :
40-1800
规格 :
100微克
价格 :
美国502
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
小鼠
应用 :
免疫印迹
更多信息或购买 :
文章摘录数: 1
| 参考文献 |
|---|
Toft Bertelsen T, Ziomkiewicz I, Houy S, Pinheiro P, Sørensen J. Regulation of Ca2+ channels by SNAP-25 via recruitment of syntaxin-1 from plasma membrane clusters. Mol Biol Cell. 2016;27:3329-3341 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
SPRY1多克隆抗体
目录# :
40-1800
规格 :
100微克
定价 :
美国502
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
小鼠
应用 :
Western Blot: Assay-dependent
物种 :
小鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells. Four mammalian Sprouty homologues (Sprouty-1-4) have been identified. One study showed that overexpressed Sprouty-1 and -2 inhibits fibroblast growth factor and vascular endothelial growth factor-induced proliferation and differentiation by repressing pathways leading to MAP kinase activation. Sprouty proteins are also endogenous inhibitors of the Ras/MAP kinase pathway that play an important role in the remodeling of branching tissues, such as in development of the lung, kidney tubules, vascular system, and breast ducts. A recent study shows that Sprouty-1 and -2 may have tumor suppressing activity in the breast, and found that both proteins are consistently down-regulated in breast carcinomas.
免疫原 :
Synthetic peptide derived from the N-terminal region of mouse and rat Sprouty-1
格式 :
液体
应用w/稀释 :
Western Blot: Assay-dependent
别名 :
hSPRY1; Protein sprouty homolog 1; sprouty 1; sprouty homolog 1 (Drosophila); sprouty homolog 1, antagonist of FGF signaling; sprouty homolog 1, antagonist of FGF signaling (Drosophila); sprouty RTK signaling antagonist 1; sprouty, Drosophila, homolog of, 1 (antagonist of FGF signaling); sprouty1; SPRY1; spry-1
更多信息或购买 :
公司信息
赛默飞世尔