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domestic rabbit
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人类, 小鼠, 大鼠, , , 斑马鱼
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免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
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文章摘录数: 262
  • 免疫组化-冰冻切片; 斑马鱼; 1:150; 图 9a
Li Y, Wang C, Zhang L, Chen B, Mo Y, Zhang J. Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier. Fluids Barriers CNS. 2022;19:40 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 s8a
Zhao Q, Dai W, Chen H, Jacobs R, Zlokovic B, Lund B, et al. Prenatal disruption of blood-brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation. Proc Natl Acad Sci U S A. 2022;119:e2113310119 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200; 图 3m
  • 免疫细胞化学; 人类; 1:200; 图 3e
Li J, Qiu C, Wei Y, Yuan W, Liu J, Cui W, et al. Human Amniotic Epithelial Stem Cell-Derived Retinal Pigment Epithelium Cells Repair Retinal Degeneration. Front Cell Dev Biol. 2021;9:737242 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 4a
  • 免疫印迹; 小鼠; 1:1000; 图 4e
Nikolakopoulou A, Wang Y, Ma Q, Sagare A, Montagne A, Huuskonen M, et al. Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A. J Exp Med. 2021;218: pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 3c
Yang C, Eleftheriadou M, Kelaini S, Morrison T, González M, Caines R, et al. Targeting QKI-7 in vivo restores endothelial cell function in diabetes. Nat Commun. 2020;11:3812 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400; 图 4a
Hou M, Han J, Li G, Kwon M, Jiang J, Emani S, et al. Multipotency of mouse trophoblast stem cells. Stem Cell Res Ther. 2020;11:55 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Kramer M, Markart P, Drakopanagiotakis F, Mamazhakypov A, Schaefer L, Didiasova M, et al. Pirfenidone inhibits motility of NSCLC cells by interfering with the urokinase system. Cell Signal. 2020;65:109432 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 s3f
Diéguez Hurtado R, Kato K, Giaimo B, Nieminen Kelhä M, Arf H, Ferrante F, et al. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes. Nat Commun. 2019;10:2817 pubmed 出版商
  • 免疫组化; 小鼠; 图 2s2
Wang Y, Sabbagh M, Gu X, Rattner A, Williams J, Nathans J. Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; 人类; 图 s7e
Souma T, Thomson B, Heinen S, Carota I, Yamaguchi S, Onay T, et al. Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP. Proc Natl Acad Sci U S A. 2018;115:1298-1303 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 1f
Pelz L, Purfürst B, Rathjen F. The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice. J Biol Chem. 2017;292:21490-21503 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6b
Hazim R, Karumbayaram S, Jiang M, Dimashkie A, Lopes V, Li D, et al. Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2017;8:217 pubmed 出版商
  • 免疫组化; 小鼠; 图 3h
Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1a
  • 免疫印迹; 人类; 图 1b
Wilkinson E, Sidaway J, Cross M. Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells. J Cell Physiol. 2018;233:186-200 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 5l
Benedicto I, Lehmann G, Ginsberg M, Nolan D, Bareja R, Elemento O, et al. Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors. Nat Commun. 2017;8:15374 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 6e
Li Y, Urban A, Midura D, Simon H, Wang Q. Proteomic characterization of epicardial-myocardial signaling reveals novel regulatory networks including a role for NF-κB in epicardial EMT. PLoS ONE. 2017;12:e0174563 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 1e
Miyashita H, Niwano H, Yoshida S, Hatou S, Inagaki E, Tsubota K, et al. Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model. Sci Rep. 2017;7:43557 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2c
  • 免疫印迹; 小鼠; 图 2c
Prasad S, Sajja R, Kaisar M, Park J, Villalba H, Liles T, et al. Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity. Redox Biol. 2017;12:58-69 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Zhang W, Li H, Ogando D, Li S, Feng M, Price F, et al. Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium. EBioMedicine. 2017;16:292-301 pubmed 出版商
  • 免疫细胞化学; 人类; 500 ug/ml; 图 4
Varadi J, Harazin A, Fenyvesi F, Réti Nagy K, Gogolak P, Vámosi G, et al. Alpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial Monolayers. PLoS ONE. 2017;12:e0170537 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s6a
Bordeleau F, Mason B, Lollis E, Mazzola M, Zanotelli M, Somasegar S, et al. Matrix stiffening promotes a tumor vasculature phenotype. Proc Natl Acad Sci U S A. 2017;114:492-497 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3a
Foerster P, Daclin M, Asm S, Faucourt M, Boletta A, Genovesio A, et al. mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis. Development. 2017;144:201-210 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4f
He Z, Forest F, Bernard A, Gauthier A, Montard R, Peoc h M, et al. Cutting and Decellularization of Multiple Corneal Stromal Lamellae for the Bioengineering of Endothelial Grafts. Invest Ophthalmol Vis Sci. 2016;57:6639-6651 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 4
Hurtado Alvarado G, Dominguez Salazar E, Velazquez Moctezuma J, Gómez González B. A2A Adenosine Receptor Antagonism Reverts the Blood-Brain Barrier Dysfunction Induced by Sleep Restriction. PLoS ONE. 2016;11:e0167236 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Che D, Zhou T, Lan Y, Xie J, Gong H, Li C, et al. High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells. Int J Mol Med. 2016;38:1815-1822 pubmed 出版商
  • 免疫印迹; 大鼠; 1:200; 图 6c
Huang L, Cao W, Deng Y, Zhu G, Han Y, Zeng H. Hypertonic saline alleviates experimentally induced cerebral oedema through suppression of vascular endothelial growth factor and its receptor VEGFR2 expression in astrocytes. BMC Neurosci. 2016;17:64 pubmed
  • 免疫细胞化学; 小鼠; 1:200; 图 2f
Mulay A, Akram K, Williams D, Armes H, Russell C, Hood D, et al. An in vitro model of murine middle ear epithelium. Dis Model Mech. 2016;9:1405-1417 pubmed
  • 免疫印迹; 小鼠; 图 3
Xiong J, Zhou M, Wang Y, Chen L, Xu W, Wang Y, et al. Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice. Sci Rep. 2016;6:34079 pubmed 出版商
  • 免疫印迹; 人类; 图 9a
Shang V, Kendall D, Roberts R. ?9-Tetrahydrocannabinol reverses TNF?-induced increase in airway epithelial cell permeability through CB2 receptors. Biochem Pharmacol. 2016;120:63-71 pubmed 出版商
  • 免疫细胞化学; 人类; 2.5 ug/ml; 图 3d
Qian Y, Li C, Jiang A, Ge S, Gu P, Fan X, et al. HIV-1 gp120 Glycoprotein Interacting with Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing Non-integrin (DC-SIGN) Down-Regulates Tight Junction Proteins to Disrupt the Blood Retinal Barrier and Increase Its Permeability. J Biol Chem. 2016;291:22977-22987 pubmed
  • 免疫组化-石蜡切片; 犬; 1:200; 图 4c
  • 免疫印迹; 犬; 1:1000; 图 3f
Ahn C, Shin D, Lee D, Kang S, Seok J, Kang H, et al. Expression of claudins, occludin, junction adhesion molecule A and zona occludens 1 in canine organs. Mol Med Rep. 2016;14:3697-703 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Soayfane Z, Tercé F, Cantiello M, Robenek H, Nauze M, Bézirard V, et al. Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets near the brush border membrane. Nutr Metab (Lond). 2016;13:48 pubmed 出版商
  • 免疫组化; 小鼠; 图 3e
  • 免疫印迹; 小鼠; 图 3a
Zhang Z, Yan J, Shi H. Role of Hypoxia Inducible Factor 1 in Hyperglycemia-Exacerbated Blood-Brain Barrier Disruption in Ischemic Stroke. Neurobiol Dis. 2016;95:82-92 pubmed 出版商
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Dauleh S, Santeramo I, Fielding C, Ward K, Herrmann A, Murray P, et al. Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum. PLoS ONE. 2016;11:e0158997 pubmed 出版商
  • 免疫组化; 人类; 图 3A
He Z, Forest F, Gain P, Rageade D, Bernard A, Acquart S, et al. 3D map of the human corneal endothelial cell. Sci Rep. 2016;6:29047 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Guo Y, Wang L, Li B, Xu H, Yang J, Zheng L, et al. Wnt/?-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling. Oncotarget. 2016;7:42513-42526 pubmed 出版商
  • 免疫组化; 小鼠; 图 4
Wang E, Geng A, Maniar A, Mui B, Gong X. Connexin 50 Regulates Surface Ball-and-Socket Structures and Fiber Cell Organization. Invest Ophthalmol Vis Sci. 2016;57:3039-46 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Wang X, Fan F, Cao Q. Modified Pulsatilla decoction attenuates oxazolone-induced colitis in mice through suppression of inflammation and epithelial barrier disruption. Mol Med Rep. 2016;14:1173-9 pubmed 出版商
  • 免疫组化; 小鼠; 图 4
Lee S, Kim H, Kim K, Lee H, Lee S, Lee D. Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon. Sci Rep. 2016;6:26923 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 4
  • 免疫印迹; 大鼠; 1:500; 图 2
Xu S, Xue X, You K, Fu J. Caveolin-1 regulates the expression of tight junction proteins during hyperoxia-induced pulmonary epithelial barrier breakdown. Respir Res. 2016;17:50 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2
Ramesh S, Singh A, Cibi D, Hausenloy D, Singh M. In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart. J Vis Exp. 2016;: pubmed 出版商
  • 免疫组化; 小鼠; 图 s6
Vorvis C, Hatziapostolou M, Mahurkar Joshi S, Koutsioumpa M, Williams J, Donahue T, et al. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2016;310:G1124-37 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 1
Ehlen L, Tödtmann J, Specht S, Kallies R, Papies J, Muller M, et al. Epithelial cell lines of the cotton rat (Sigmodon hispidus) are highly susceptible in vitro models to zoonotic Bunya-, Rhabdo-, and Flaviviruses. Virol J. 2016;13:74 pubmed 出版商
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Iwai Takekoshi L, Ramos A, Schaler A, Weinreb S, Blazeski R, Mason C. Retinal pigment epithelial integrity is compromised in the developing albino mouse retina. J Comp Neurol. 2016;524:3696-3716 pubmed 出版商
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Waisbourd Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, et al. The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17. Hepatology. 2016;64:880-93 pubmed 出版商
  • 免疫印迹; 大鼠; 图 6
Liu Z, Wang S, Liu J, Wang F, Liu Y, Zhao Y. Leukocyte Infiltration Triggers Seizure Recurrence in a Rat Model of Temporal Lobe Epilepsy. Inflammation. 2016;39:1090-8 pubmed 出版商
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Trembley M, Velasquez L, Small E. Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration. J Vis Exp. 2016;: pubmed 出版商
  • 免疫组化; 鸡; 1:100; 图 1
Nitzan E, Avraham O, Kahane N, Ofek S, Kumar D, Kalcheim C. Dynamics of BMP and Hes1/Hairy1 signaling in the dorsal neural tube underlies the transition from neural crest to definitive roof plate. BMC Biol. 2016;14:23 pubmed 出版商
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Wu W, Zeng Y, Li Z, Li Q, Xu H, Yin Z. Features specific to retinal pigment epithelium cells derived from three-dimensional human embryonic stem cell cultures - a new donor for cell therapy. Oncotarget. 2016;7:22819-33 pubmed 出版商
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Viringipurampeer I, Metcalfe A, Bashar A, Sivak O, Yanai A, Mohammadi Z, et al. NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration. Hum Mol Genet. 2016;25:1501-16 pubmed 出版商
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Bassey Archibong B, Kwiecien J, Milosavljevic S, Hallett R, Rayner L, Erb M, et al. Kaiso depletion attenuates transforming growth factor-? signaling and metastatic activity of triple-negative breast cancer cells. Oncogenesis. 2016;5:e208 pubmed 出版商
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Schrade A, Kyrönlahti A, Akinrinade O, Pihlajoki M, Fischer S, Rodriguez V, et al. GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells. Endocrinology. 2016;157:2416-31 pubmed 出版商
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Escobedo N, Proulx S, Karaman S, Dillard M, Johnson N, Detmar M, et al. Restoration of lymphatic function rescues obesity in Prox1-haploinsufficient mice. JCI Insight. 2016;1: pubmed
  • 免疫细胞化学; 人类; 1:200; 图 6
  • 免疫组化; 小鼠; 1:200; 图 5
Ibrahim A, Mander S, Hussein K, Elsherbiny N, Smith S, Al Shabrawey M, et al. Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration. Oncotarget. 2016;7:8532-45 pubmed 出版商
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Li H, Ruberu K, Karl T, Garner B. Cerebral Apolipoprotein-D Is Hypoglycosylated Compared to Peripheral Tissues and Is Variably Expressed in Mouse and Human Brain Regions. PLoS ONE. 2016;11:e0148238 pubmed 出版商
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Shang V, O Sullivan S, Kendall D, Roberts R. The endogenous cannabinoid anandamide increases human airway epithelial cell permeability through an arachidonic acid metabolite. Pharmacol Res. 2016;105:152-63 pubmed 出版商
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Loebel D, Plageman T, Tang T, Jones V, Muccioli M, Tam P. Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction. Biol Open. 2016;5:130-9 pubmed 出版商
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Stebbins M, Wilson H, Canfield S, Qian T, Palecek S, Shusta E. Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells. Methods. 2016;101:93-102 pubmed 出版商
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Nagaoka K, Fujii K, Zhang H, Usuda K, Watanabe G, Ivshina M, et al. CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis. Oncogene. 2016;35:2893-901 pubmed 出版商
. Effects of Volatile Anesthetics versus Ketamine on Blood-Brain Barrier Permeability via Lipid-Mediated Alterations of Endothelial Cell Membranes. J Pharmacol Exp Ther. 2023;385:135-145 pubmed 出版商
Zhou Y, Zhang Z, Sun Y, Zhou D, Zhao Y, Li J, et al. Liangxue Tongyu Prescription Alleviates Brain Damage in Acute Intracerebral Hemorrhage Rats by Regulating Intestinal Mucosal Barrier Function. Evid Based Complement Alternat Med. 2022;2022:2197763 pubmed 出版商
Kwon Y, Banskota S, Wang H, Rossi L, Grondin J, Syed S, et al. Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice. Nat Commun. 2022;13:7617 pubmed 出版商
Caneparo C, Chabaud S, Fradette J, Bolduc S. Engineered human organ-specific urethra as a functional substitute. Sci Rep. 2022;12:21346 pubmed 出版商
Raghavan S, Brishti M, COLLIER D, Leo M. Hypoxia induces purinergic receptor signaling to disrupt endothelial barrier function. Front Physiol. 2022;13:1049698 pubmed 出版商
Zhou R, Li J, Wang R, Chen Z, Zhou F. Moderate systemic therapeutic hypothermia is insufficient to protect blood-spinal cord barrier in spinal cord injury. Front Neurol. 2022;13:1041099 pubmed 出版商
Gerstmann K, Kindbeiter K, Telley L, Bozon M, Reynaud F, Th xe9 oulle E, et al. A balance of noncanonical Semaphorin signaling from the cerebrospinal fluid regulates apical cell dynamics during corticogenesis. Sci Adv. 2022;8:eabo4552 pubmed 出版商
Zhang X, Qiu J, Huang F, Shan K, Zhang C. Type 2 Diabetes Mellitus Makes Corneal Endothelial Cells Vulnerable to Ultraviolet A-Induced Oxidative Damage Via Decreased DJ-1/Nrf2/NQO1 Pathway. Invest Ophthalmol Vis Sci. 2022;63:25 pubmed 出版商
Park J, Gabel A, Kassir P, Kang L, Chowdhary P, Osei Ntansah A, et al. N-myc downstream regulated gene 1 (ndrg1) functions as a molecular switch for cellular adaptation to hypoxia. elife. 2022;11: pubmed 出版商
Tsou H, Wang P, Ting T, Ping Y, Liu T, Cheng H, et al. Effect of heated tobacco products and traditional cigarettes on pulmonary toxicity and SARS-CoV-2-induced lung injury. Toxicology. 2022;479:153318 pubmed 出版商
Sifat A, Archie S, Nozohouri S, Villalba H, Zhang Y, Sharma S, et al. Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome. Fluids Barriers CNS. 2022;19:74 pubmed 出版商
Zhu Y, Chew K, Wu M, Karawita A, McCallum G, Steele L, et al. Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells. PLoS Biol. 2022;20:e3001728 pubmed 出版商
Hazim R, Paniagua A, Tang L, Yang K, Kim K, Stiles L, et al. Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium. J Biol Chem. 2022;298:102286 pubmed 出版商
Zolotoff C, Puech C, Roche F, Perek N. Effects of intermittent hypoxia with thrombin in an in vitro model of human brain endothelial cells and their impact on PAR-1/PAR-3 cleavage. Sci Rep. 2022;12:12305 pubmed 出版商
Gomes de Almeida P, Rifes P, Martins Jesus A, Pinheiro G, Andrade R, Thorsteinsd xf3 ttir S. Cell-Fibronectin Interactions and Actomyosin Contractility Regulate the Segmentation Clock and Spatio-Temporal Somite Cleft Formation during Chick Embryo Somitogenesis. Cells. 2022;11: pubmed 出版商
Molins Guti xe9 rrez G, Martorell J, Salazar Martín A, Balcells M. A Dynamic, In Vitro BBB Model to Study the Effects of Varying Levels of Shear Stress. Methods Mol Biol. 2022;2492:175-190 pubmed 出版商
Chou H, Cheng C, Yang C, Lin T, Liu Y, Tan T, et al. DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction. J Biomed Sci. 2022;29:40 pubmed 出版商
Meena A, Shukla P, Bell B, Giorgianni F, Caires R, Fernández Peña C, et al. TRPV6 channel mediates alcohol-induced gut barrier dysfunction and systemic response. Cell Rep. 2022;39:110937 pubmed 出版商
Zhang L, Tang S, Ma Y, Liu J, Monnier P, Li H, et al. RGMa Participates in the Blood-Brain Barrier Dysfunction Through BMP/BMPR/YAP Signaling in Multiple Sclerosis. Front Immunol. 2022;13:861486 pubmed 出版商
Sorin S, Kubota S, Hamidi S, Yokomizo Nakano T, Vaeteewoottacharn K, Wongkham S, et al. HMGN3 represses transcription of epithelial regulators to promote migration of cholangiocarcinoma in a SNAI2-dependent manner. FASEB J. 2022;36:e22345 pubmed 出版商
Branca J, Carrino D, Paternostro F, Morucci G, Fiorillo C, Nicoletti C, et al. The Protection of Zinc against Acute Cadmium Exposure: A Morphological and Molecular Study on a BBB In Vitro Model. Cells. 2022;11: pubmed 出版商
Wang W, Su L, Wang Y, Li C, Ji F, Jiao J. Endothelial Cells Mediated by UCP2 Control the Neurogenic-to-Astrogenic Neural Stem Cells Fate Switch During Brain Development. Adv Sci (Weinh). 2022;9:e2105208 pubmed 出版商
Ayloo S, Lazo C, Sun S, Zhang W, Cui B, Gu C. Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier. Neuron. 2022;110:1641-1655.e6 pubmed 出版商
Sivakumar S, Qi S, Cheng N, Sathe A, Kanchwala M, Kumar A, et al. TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling. Cell Rep. 2022;38:110395 pubmed 出版商
Yue Q, Zhou X, Zhang Z, Hoi M. Murine Beta-Amyloid (1-42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors. Int J Mol Sci. 2022;23: pubmed 出版商
Rofaani E, Huang B, Liang F, Peng J, Chen Y. Reconstituted basement membrane enables airway epithelium modeling and nanoparticle toxicity testing. Int J Biol Macromol. 2022;204:300-309 pubmed 出版商
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产品类型 :
产品名称 :
目录# :
规格 :
价格 :
克隆性 :
纯度 :
宿主 :
反应物种 :
狗, 人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 2.5-5 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
物种 :
狗, 人类, 小鼠, 大鼠
抗体亚型 :
储存 :
描述 :
ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
免疫原 :
Synthetic peptide in the middle region of the ZO-1 protein.
格式 :
应用w/稀释 :
Immunocytochemistry: 2.5-5 µg/mL, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
别名 :
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
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公司总部: 美国