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NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
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产品名称 :
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宿主 :
domestic rabbit
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克隆名称 :
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
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文章摘录数: 68
  • 免疫组化; 小鼠; 1:200; 图 3p
Hopkins J, Asada K, Leung A, Papadaki V, Davaapil H, Morrison M, et al. PRELP Regulates Cell-Cell Adhesion and EMT and Inhibits Retinoblastoma Progression. Cancers (Basel). 2022;14: pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4c
Hagbom M, de Faria F, Winberg M, Westerberg S, Nordgren J, Sharma S, et al. Neurotrophic Factors Protect the Intestinal Barrier from Rotavirus Insult in Mice. MBio. 2020;11: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 5s1a
Benz F, Wichitnaowarat V, Lehmann M, Germano R, Mihova D, Macas J, et al. Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice. elife. 2019;8: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4a
Qi X, Pay S, Yan Y, Thomas J, Lewin A, Chang L, et al. Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration. Mol Ther. 2017;25:917-927 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1e
  • 免疫细胞化学; 人类; 1:200; 图 2i
Salomon J, Gaston C, Magescas J, Duvauchelle B, Canioni D, Sengmanivong L, et al. Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity. Nat Commun. 2017;8:13998 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 2
Tamasas B, Cox T. Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model. J Dent Res. 2017;96:315-322 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1
Chen Z, Wang Q, Asmani M, Li Y, Liu C, Li C, et al. Lung Microtissue Array to Screen the Fibrogenic Potential of Carbon Nanotubes. Sci Rep. 2016;6:31304 pubmed 出版商
  • 免疫组化; 人类; 图 2e
Seo H, Jeong H, Joo H, Choi S, Park C, Kim J, et al. Intrinsic FGF2 and FGF5 promotes angiogenesis of human aortic endothelial cells in 3D microfluidic angiogenesis system. Sci Rep. 2016;6:28832 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 7
Fernandez Godino R, Garland D, Pierce E. Isolation, culture and characterization of primary mouse RPE cells. Nat Protoc. 2016;11:1206-18 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 5
Hintermann E, Bayer M, Ehser J, Aurrand Lions M, Pfeilschifter J, Imhof B, et al. Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis. Cell Adh Migr. 2016;10:419-33 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 表 1
May Simera H. Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea. J Vis Exp. 2016;:53559 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:50; 图 s3
Stabler C, Caires L, Mondrinos M, Marcinkiewicz C, Lazarovici P, Wolfson M, et al. Enhanced Re-Endothelialization of Decellularized Rat Lungs. Tissue Eng Part C Methods. 2016;22:439-50 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
  • 免疫印迹; 大鼠; 图 4
Egan C, Sodhi C, Good M, Lin J, Jia H, Yamaguchi Y, et al. Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis. J Clin Invest. 2016;126:495-508 pubmed
Feng J, Yang W, Luan F, Ma F, Wang Y, Zhang Y, et al. The Protective Role of Apelin in the Early Stages of Diabetic Retinopathy. Int J Mol Sci. 2022;23: pubmed 出版商
Poggel C, Adams T, Janzen R, Hofmann A, Hardt O, Roeb E, et al. Isolation of Hepatocytes from Liver Tissue by a Novel, Semi-Automated Perfusion Technology. Biomedicines. 2022;10: pubmed 出版商
Wu Z, Bai X, Lu Z, Liu S, Jiang H. LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination. J Immunol Res. 2022;2022:6450721 pubmed 出版商
Avagliano C, De Caro C, Cuozzo M, Liguori F, La Rana G, Micheli L, et al. Phaseolus vulgaris extract ameliorates high-fat diet-induced colonic barrier dysfunction and inflammation in mice by regulating peroxisome proliferator-activated receptor expression and butyrate levels. Front Pharmacol. 2022;13:930832 pubmed 出版商
Harkins D, Harvey T, Atterton C, Miller I, Currey L, Oishi S, et al. Hydrocephalus in Nfix-/- Mice Is Underpinned by Changes in Ependymal Cell Physiology. Cells. 2022;11: pubmed 出版商
Morgan R, Manfredi C, Easley K, Watkins L, Hunt W, Goudy S, et al. A medium composition containing normal resting glucose that supports differentiation of primary human airway cells. Sci Rep. 2022;12:1540 pubmed 出版商
Iennaco R, Formenti G, Trovesi C, Rossi R, Zuccato C, Lischetti T, et al. The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities. Cell Death Differ. 2022;: pubmed 出版商
Lai A, Ng T, Hung V, Tam K, Cheung C, Chung S, et al. Exacerbated VEGF up-regulation accompanies diabetes-aggravated hemorrhage in mice after experimental cerebral ischemia and delayed reperfusion. Neural Regen Res. 2022;17:1566-1575 pubmed 出版商
Allenspach K, Mochel J. Current diagnostics for chronic enteropathies in dogs. Vet Clin Pathol. 2022;50 Suppl 1:18-28 pubmed 出版商
Cantoni F, Werr G, Barbe L, Porras A, Tenje M. A microfluidic chip carrier including temperature control and perfusion system for long-term cell imaging. HardwareX. 2021;10:e00245 pubmed 出版商
Lv Y, Wu X, Chen J, Shao F. Ruscogenin attenuated tight junction injury and tumor migration in colorectal liver metastasis mice via regulating TRAP1. Transl Cancer Res. 2021;10:1470-1483 pubmed 出版商
Kim Y, Roh E, Joshi H, Shin H, Choi H, Kwon S, et al. Bazedoxifene, a Selective Estrogen Receptor Modulator, Promotes Functional Recovery in a Spinal Cord Injury Rat Model. Int J Mol Sci. 2021;22: pubmed 出版商
Escrevente C, Falcão A, Hall M, Lopes da Silva M, Antas P, Mesquita M, et al. Formation of Lipofuscin-Like Autofluorescent Granules in the Retinal Pigment Epithelium Requires Lysosome Dysfunction. Invest Ophthalmol Vis Sci. 2021;62:39 pubmed 出版商
Lynn K, Easley K, Martinez F, Reed R, Schlingmann B, Koval M. Asymmetric distribution of dynamin-2 and β-catenin relative to tight junction spikes in alveolar epithelial cells. Tissue Barriers. 2021;9:1929786 pubmed 出版商
Kim K, Wang X, Ragonnaud E, Bodogai M, Illouz T, DeLuca M, et al. Therapeutic B-cell depletion reverses progression of Alzheimer's disease. Nat Commun. 2021;12:2185 pubmed 出版商
Motta J, Palese S, Giorgio C, Chapman K, Denadai Souza A, Rousset P, et al. Increased Mucosal Thrombin is Associated with Crohn's Disease and Causes Inflammatory Damage through Protease-activated Receptors Activation. J Crohns Colitis. 2021;15:787-799 pubmed 出版商
Yuan L, van der Mei H, Busscher H, Peterson B. Two-Stage Interpretation of Changes in TEER of Intestinal Epithelial Layers Protected by Adhering Bifidobacteria During E. coli Challenges. Front Microbiol. 2020;11:599555 pubmed 出版商
Salman M, Marsh G, Kusters I, Delince M, Di Caprio G, Upadhyayula S, et al. Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging. Front Bioeng Biotechnol. 2020;8:573775 pubmed 出版商
Takeishi K, Collin de l Hortet A, Wang Y, Handa K, Guzman Lepe J, Matsubara K, et al. Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells. Cell Rep. 2020;31:107711 pubmed 出版商
Ittner C, Burek M, Störk S, Nagai M, Förster C. Increased Catecholamine Levels and Inflammatory Mediators Alter Barrier Properties of Brain Microvascular Endothelial Cells in vitro. Front Cardiovasc Med. 2020;7:73 pubmed 出版商
De Cian M, Gregoire E, Le Rolle M, Lachambre S, Mondin M, Bell S, et al. R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth. Cell Death Differ. 2020;: pubmed 出版商
Tsai Y, Ruan J, Chang C, Ko M, Chou H, Lin C, et al. Antrodia cinnamomea Confers Obesity Resistance and Restores Intestinal Barrier Integrity in Leptin-deficient Obese Mice. Nutrients. 2020;12: pubmed 出版商
Krüger M, Oosterhoff L, van Wolferen M, Schiele S, Walther A, Geijsen N, et al. Cellulose Nanofibril Hydrogel Promotes Hepatic Differentiation of Human Liver Organoids. Adv Healthc Mater. 2020;9:e1901658 pubmed 出版商
Kumar H, Lim C, Choi H, Joshi H, Kim K, Kim Y, et al. Elevated TRPV4 Levels Contribute to Endothelial Damage and Scarring in Experimental Spinal Cord Injury. J Neurosci. 2020;40:1943-1955 pubmed 出版商
Rekima A, Bonnart C, Macchiaverni P, Metcalfe J, Tulic M, Halloin N, et al. A role for early oral exposure to house dust mite allergens through breast milk in IgE-mediated food allergy susceptibility. J Allergy Clin Immunol. 2020;145:1416-1429.e11 pubmed 出版商
Helm E, Curry S, De Mille C, Schweer W, Burrough E, Gabler N. Impact of viral disease hypophagia on pig jejunal function and integrity. PLoS ONE. 2020;15:e0227265 pubmed 出版商
Falasconi A, Biagioni M, Novelli E, Piano I, Gargini C, Strettoi E. Retinal Phenotype in the rd9 Mutant Mouse, a Model of X-Linked RP. Front Neurosci. 2019;13:991 pubmed 出版商
Ladel S, Schlossbauer P, Flamm J, Luksch H, Mizaikoff B, Schindowski K. Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650. Pharmaceutics. 2019;11: pubmed 出版商
Libanje F, Raingeaud J, Luan R, Thomas Z, Zajac O, Veiga J, et al. ROCK2 inhibition triggers the collective invasion of colorectal adenocarcinomas. EMBO J. 2019;38:e99299 pubmed 出版商
Xia X, Liu Y, Hodgson A, Xu D, Guo W, Yu H, et al. EspF is crucial for Citrobacter rodentium-induced tight junction disruption and lethality in immunocompromised animals. PLoS Pathog. 2019;15:e1007898 pubmed 出版商
Carvalho J, Fortunato I, Fonseca C, Pezzarossa A, Barbacena P, Domínguez Cejudo M, et al. Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration. elife. 2019;8: pubmed 出版商
Kawauchi S, Horibe S, Sasaki N, Tanahashi T, Mizuno S, Hamaguchi T, et al. Inhibitory Effects of Sodium Alginate on Hepatic Steatosis in Mice Induced by a Methionine- and Choline-deficient Diet. Mar Drugs. 2019;17: pubmed 出版商
Harder J, Menon R, Otto E, Zhou J, Eddy S, Wys N, et al. Organoid single cell profiling identifies a transcriptional signature of glomerular disease. JCI Insight. 2019;4: pubmed 出版商
Flores Martínez Á, García Núñez A, Rojas A, Cano D. Stabilization of HIF-2? impacts pancreas growth. Sci Rep. 2018;8:13713 pubmed 出版商
Schiffmacher A, Adomako Ankomah A, Xie V, Taneyhill L. Cadherin-6B proteolytic N-terminal fragments promote chick cranial neural crest cell delamination by regulating extracellular matrix degradation. Dev Biol. 2018;444 Suppl 1:S237-S251 pubmed 出版商
Hönig E, Ringer K, Dewes J, von Mach T, Kamm N, Kreitzer G, et al. Galectin-3 modulates the polarized surface delivery of ?1-integrin in epithelial cells. J Cell Sci. 2018;131: pubmed 出版商
Forbes T, Howden S, Lawlor K, Phipson B, Maksimovic J, Hale L, et al. Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms. Am J Hum Genet. 2018;102:816-831 pubmed 出版商
Lai H, Liu A, Ng H, Goldfinger M, Chau T, DeFelice J, et al. Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues. Nat Commun. 2018;9:1066 pubmed 出版商
Liu X, Wang Y, Liu F, Zhang M, Song H, Zhou B, et al. Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling. Sci Signal. 2018;11: pubmed 出版商
Zhou W, Chen C, Shi Y, Wu Q, Gimple R, Fang X, et al. Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy. Cell Stem Cell. 2017;21:591-603.e4 pubmed 出版商
Gómez Escudero J, Moreno V, Martín Alonso M, Hernández Riquer M, Feinberg T, Colmenar A, et al. E-cadherin cleavage by MT2-MMP regulates apical junctional signaling and epithelial homeostasis in the intestine. J Cell Sci. 2017;130:4013-4027 pubmed 出版商
Kazatskaya A, Kuhns S, Lambacher N, Kennedy J, Brear A, McManus G, et al. Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells. Genetics. 2017;207:1423-1440 pubmed 出版商
Neuhaus W, Kramer T, Neuhoff A, Gölz C, Thal S, Förster C. Multifaceted Mechanisms of WY-14643 to Stabilize the Blood-Brain Barrier in a Model of Traumatic Brain Injury. Front Mol Neurosci. 2017;10:149 pubmed 出版商
Song Y, Du D, Li L, Xu J, Dutta P, Lin Y. In Vitro Study of Receptor-Mediated Silica Nanoparticles Delivery across Blood-Brain Barrier. ACS Appl Mater Interfaces. 2017;9:20410-20416 pubmed 出版商
Andrews A, Lutton E, Cannella L, Reichenbach N, Razmpour R, Seasock M, et al. Characterization of human fetal brain endothelial cells reveals barrier properties suitable for in vitro modeling of the BBB with syngenic co-cultures. J Cereb Blood Flow Metab. 2018;38:888-903 pubmed 出版商
Coulthard L, Hawksworth O, Li R, Balachandran A, Lee J, Sepehrband F, et al. Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCζ. J Neurosci. 2017;37:5395-5407 pubmed 出版商
Bai Y, Zhang Y, Hua J, Yang X, Zhang X, Duan M, et al. Silencing microRNA-143 protects the integrity of the blood-brain barrier: implications for methamphetamine abuse. Sci Rep. 2016;6:35642 pubmed 出版商
Mariotti S, Barravecchia I, Vindigni C, Pucci A, Balsamo M, Libro R, et al. MICAL2 is a novel human cancer gene controlling mesenchymal to epithelial transition involved in cancer growth and invasion. Oncotarget. 2016;7:1808-25 pubmed 出版商
Deosarkar S, PRABHAKARPANDIAN B, Wang B, Sheffield J, Krynska B, Kiani M. A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip. PLoS ONE. 2015;10:e0142725 pubmed 出版商
Koudelkova P, Weber G, Mikulits W. Liver Sinusoidal Endothelial Cells Escape Senescence by Loss of p19ARF. PLoS ONE. 2015;10:e0142134 pubmed 出版商
de Vallière C, Vidal S, Clay I, Jurisic G, Tcymbarevich I, Lang S, et al. The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment. Am J Physiol Gastrointest Liver Physiol. 2015;309:G475-90 pubmed 出版商
O Shaughnessy Kirwan A, Signolet J, Costello I, Gharbi S, Hendrich B. Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification. Development. 2015;142:2586-97 pubmed 出版商
Peng H, Li C, Kadow S, Henry B, Steinmann J, Becker K, et al. Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis. J Mol Med (Berl). 2015;93:675-89 pubmed 出版商
Visconti B, Paolino G, Carotti S, Pendolino A, Morini S, Richetta A, et al. Immunohistochemical expression of VDR is associated with reduced integrity of tight junction complex in psoriatic skin. J Eur Acad Dermatol Venereol. 2015;29:2038-42 pubmed 出版商
Hagel C, Krasemann S, Löffler J, Puschel K, Magnus T, Glatzel M. Upregulation of Shiga toxin receptor CD77/Gb3 and interleukin-1? expression in the brain of EHEC patients with hemolytic uremic syndrome and neurologic symptoms. Brain Pathol. 2015;25:146-56 pubmed 出版商
产品类型 :
产品名称 :
目录# :
规格 :
价格 :
克隆性 :
纯度 :
宿主 :
反应物种 :
狗, 人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 5-10 µg/mL, Immunohistochemistry (Frozen): 2 µg/mL, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: Assay-dependent
物种 :
狗, 人类, 小鼠, 大鼠
克隆 :
抗体亚型 :
储存 :
描述 :
ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
免疫原 :
Synthetic peptide derived from the N-terminal region of human, dog, mouse, and rat ZO-1
格式 :
应用w/稀释 :
Immunocytochemistry: 5-10 µg/mL, Immunohistochemistry (Frozen): 2 µg/mL, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: Assay-dependent
别名 :
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
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公司总部: 美国