产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Occludin Polyclonal Antibody
目录 :
40-4700
规格 :
100微克
价格 :
美国450.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 52
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:100; 图 5a
Fayad R, Rojas M, Partisani M, Finetti P, Dib S, Abélanet S, et al. EFA6B regulates a stop signal for collective invasion in breast cancer. Nat Commun. 2021;12:2198 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:150; 图 6a
  • 免疫印迹; 大鼠; 1:300; 图 6g
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  • 免疫印迹; 大鼠; 1:1000; 图 4
Hurtado Alvarado G, Dominguez Salazar E, Velazquez Moctezuma J, Gómez González B. A2A Adenosine Receptor Antagonism Reverts the Blood-Brain Barrier Dysfunction Induced by Sleep Restriction. PLoS ONE. 2016;11:e0167236 pubmed 出版商
  • 免疫印迹; 犬
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Ma X, Jin H, Chu X, Dai W, Tang W, Zhu J, et al. The Host CYP1A1-Microbiota Metabolic Axis Promotes Gut Barrier Disruption in Methicillin-Resistant Staphylococcus aureus-Induced Abdominal Sepsis. Front Microbiol. 2022;13:802409 pubmed 出版商
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Zhao X, Zheng S, Wei S, Tian Q, Tao Y, Bo R, et al. The protective effect and potential mechanisms of eugenol against Salmonella in vivo and in vitro. Poult Sci. 2022;101:101801 pubmed 出版商
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Xia B, Wu W, Fang W, Wen X, Xie J, Zhang H. Heat stress-induced mucosal barrier dysfunction is potentially associated with gut microbiota dysbiosis in pigs. Anim Nutr. 2022;8:289-299 pubmed 出版商
Yang Y, Fan X, Ji Y, Li J, Dai Z, Wu Z. Glycine represses endoplasmic reticulum stress-related apoptosis and improves intestinal barrier by activating mammalian target of rapamycin complex 1 signaling. Anim Nutr. 2022;8:1-9 pubmed 出版商
Zhang X, Jiao X, Wu D, Chen F, Ding Z, Wang Y, et al. Benzophenone-3 breaches mouse Sertoli cell barrier and alters F-actin organization without evoking apoptosis. Environ Toxicol. 2022;37:28-40 pubmed 出版商
Seo H, Seong H, Kim G, Jo Y, Cheon S, Song Y, et al. Development of Anti-inflammatory Probiotic Limosilactobacillus reuteri EFEL6901 as Kimchi Starter: in vitro and In vivo Evidence. Front Microbiol. 2021;12:760476 pubmed 出版商
Chataigner M, Lucas C, Di Miceli M, Pallet V, Layé S, Mehaignerie A, et al. Dietary Fish Hydrolysate Improves Memory Performance Through Microglial Signature Remodeling During Aging. Front Nutr. 2021;8:750292 pubmed 出版商
Xu X, Gao W, Li L, Hao J, Yang B, Wang T, et al. Annexin A1 protects against cerebral ischemia-reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway. J Neuroinflammation. 2021;18:119 pubmed 出版商
Hasegawa T, Mizugaki A, Inoue Y, Kato H, Murakami H. Cystine reduces tight junction permeability and intestinal inflammation induced by oxidative stress in Caco-2 cells. Amino Acids. 2021;53:1021-1032 pubmed 出版商
Chioccarelli T, Migliaccio M, Suglia A, Manfrevola F, Porreca V, Diano N, et al. Characterization of Estrogenic Activity and Site-Specific Accumulation of Bisphenol-A in Epididymal Fat Pad: Interfering Effects on the Endocannabinoid System and Temporal Progression of Germ Cells. Int J Mol Sci. 2021;22: pubmed 出版商
McGrath C, Sch xfc ller S. Determining Shiga Toxin-Producing Escherichia coli Interactions with Human Intestinal Epithelium in a Microaerobic Vertical Diffusion Chamber. Methods Mol Biol. 2021;2291:273-283 pubmed 出版商
Jia H, Zhang Y, Si X, Jin Y, Jiang D, Dai Z, et al. Quercetin Alleviates Oxidative Damage by Activating Nuclear Factor Erythroid 2-Related Factor 2 Signaling in Porcine Enterocytes. Nutrients. 2021;13: pubmed 出版商
Scalisi J, Balau B, Deneyer L, Bouchat J, Gilloteaux J, Nicaise C. Blood-brain barrier permeability towards small and large tracers in a mouse model of osmotic demyelination syndrome. Neurosci Lett. 2021;746:135665 pubmed 出版商
Salman M, Marsh G, Kusters I, Delince M, Di Caprio G, Upadhyayula S, et al. Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging. Front Bioeng Biotechnol. 2020;8:573775 pubmed 出版商
Hempt C, Kaiser J, Scholder O, Buerki Thurnherr T, Hofmann H, Rippl A, et al. The impact of synthetic amorphous silica (E 551) on differentiated Caco-2 cells, a model for the human intestinal epithelium. Toxicol In Vitro. 2020;67:104903 pubmed 出版商
Johnson A, Harkema J, Nelson A, Dickinson J, Kalil J, Duryee M, et al. MyD88 regulates a prolonged adaptation response to environmental dust exposure-induced lung disease. Respir Res. 2020;21:97 pubmed 出版商
Ducray H, Globa L, Pustovyy O, Roberts M, Rudisill M, Vodyanoy V, et al. Prevention of excessive exercise-induced adverse effects in rats with Bacillus subtilis BSB3. J Appl Microbiol. 2020;128:1163-1178 pubmed 出版商
Sayoc Becerra A, Krishnan M, Fan S, Jimenez J, HERNANDEZ R, Gibson K, et al. The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction. Inflamm Bowel Dis. 2020;26:407-422 pubmed 出版商
Zhou Y, Huang F, Liu Y, Li D, Zhou Y, Shen L, et al. TGF-β1 relieves epithelial-mesenchymal transition reduction in hypospadias induced by DEHP in rats. Pediatr Res. 2020;87:639-646 pubmed 出版商
Dom xed nguez Salazar E, Hurtado Alvarado G, Medina Flores F, Dorantes J, Gonz xe1 lez Flores O, Contis Montes de Oca A, et al. Chronic sleep loss disrupts blood-testis and blood-epididymis barriers, and reduces male fertility. J Sleep Res. 2020;29:e12907 pubmed 出版商
Gunasekaran A, Eckert J, Burge K, Zheng W, Yu Z, Kessler S, et al. Hyaluronan 35 kDa enhances epithelial barrier function and protects against the development of murine necrotizing enterocolitis. Pediatr Res. 2020;87:1177-1184 pubmed 出版商
Noval Rivas M, Wakita D, Franklin M, Carvalho T, Abolhesn A, Gomez A, et al. Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation. Immunity. 2019;51:508-521.e6 pubmed 出版商
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Zhou Z, Bian C, Luo Z, Guille C, Ogunrinde E, Wu J, et al. Progesterone decreases gut permeability through upregulating occludin expression in primary human gut tissues and Caco-2 cells. Sci Rep. 2019;9:8367 pubmed 出版商
Oztas E, Yılmaz T, Guzel E, Sezer Z, Okyar A, Ozhan G. Gliclazide alone or in combination with atorvastatin ameliorated reproductive damage in streptozotocin-induced type 2 diabetic male rats. Saudi Pharm J. 2019;27:422-431 pubmed 出版商
Chen L, Li H, Li J, Chen Y, Yang Y. Lactobacillus rhamnosus GG treatment improves intestinal permeability and modulates microbiota dysbiosis in an experimental model of sepsis. Int J Mol Med. 2019;43:1139-1148 pubmed 出版商
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Jin X, Liao Y, Tan X, Wang G, Zhao F, Jin Y. Involvement of CYP2E1 in the Course of Brain Edema Induced by Subacute Poisoning With 1,2-Dichloroethane in Mice. Front Pharmacol. 2018;9:1317 pubmed 出版商
Janardhan K, Jensen H, Clayton N, Herbert R. Immunohistochemistry in Investigative and Toxicologic Pathology. Toxicol Pathol. 2018;46:488-510 pubmed 出版商
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Allam O, Samarani S, Mehraj V, Jenabian M, Tremblay C, Routy J, et al. HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation. PLoS ONE. 2018;13:e0194185 pubmed 出版商
Menard C, Pfau M, Hodes G, Kana V, Wang V, Bouchard S, et al. Social stress induces neurovascular pathology promoting depression. Nat Neurosci. 2017;20:1752-1760 pubmed 出版商
Lee J, Lee H, Kim T, Kim M, Park Y, Kim J, et al. Obesogenic diet-induced gut barrier dysfunction and pathobiont expansion aggravate experimental colitis. PLoS ONE. 2017;12:e0187515 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
Occludin Polyclonal Antibody
目录# :
40-4700
规格 :
100微克
价格 :
美国450.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
狗, 人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 6 µg/mL, Western Blot: 1-3 µg/mL
物种 :
狗, 人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa. Occludin is thought to be involved in regulating both the localization and the function of occludin. Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution. Overall structural features of the occludin protein are highly conserved in all the species examined. Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.
免疫原 :
Synthetic peptide derived from the C-terminal region of the human occludin protein
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 6 µg/mL, Western Blot: 1-3 µg/mL
别名 :
AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国