产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Alpha-Smooth Muscle Actin Monoclonal Antibody (1A4), eFluor™ 570, eBioscience
目录 :
41-9760-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
eFluor 570
克隆名称 :
1A4
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 26
参考文献
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Hassel C, Gausser xe8 s B, Guzylack Piriou L, Foucras G. Ductal Macrophages Predominate in the Immune Landscape of the Lactating Mammary Gland. Front Immunol. 2021;12:754661 pubmed 出版商
Nagavally R, Sunilkumar S, Akhtar M, Trombetta L, Ford S. Chrysin Ameliorates Cyclosporine-A-Induced Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial-Mesenchymal Transition. Int J Mol Sci. 2021;22: pubmed 出版商
El Sherbiny M, Atef H, Eladl M, Mohamed A, El Shafey M, Ali H, et al. Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production. Front Pharmacol. 2021;12:631216 pubmed 出版商
Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, et al. Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy. Cell Death Dis. 2021;12:470 pubmed 出版商
Gilmore A, Flaherty S, Somasundaram V, Scheiblin D, Lockett S, Wink D, et al. An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients. Commun Biol. 2021;4:477 pubmed 出版商
Xu Y, Wang N, Tan H, Li S, Zhang C, Feng Y. Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease. Hepatol Int. 2021;15:350-365 pubmed 出版商
Gilles G, McCulloch A, Brakebusch C, Herum K. Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction. PLoS ONE. 2020;15:e0241390 pubmed 出版商
Gorchs L, Ahmed S, Mayer C, Knauf A, Fernández Moro C, Svensson M, et al. The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity. Sci Rep. 2020;10:17444 pubmed 出版商
Suess P, Smith S, Morrissey J. Platelet polyphosphate induces fibroblast chemotaxis and myofibroblast differentiation. J Thromb Haemost. 2020;18:3043-3052 pubmed 出版商
Gonzalez B, Perez Nevarez M, Mirza A, Perez M, Lin Y, Hsu C, et al. Physiologically Relevant Fluid-Induced Oscillatory Shear Stress Stimulation of Mesenchymal Stem Cells Enhances the Engineered Valve Matrix Phenotype. Front Cardiovasc Med. 2020;7:69 pubmed 出版商
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, et al. Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth. Cell Rep. 2020;31:107628 pubmed 出版商
Somarathna M, Isayeva Waldrop T, Al Balas A, Guo L, Lee T. A Novel Model of Balloon Angioplasty Injury in Rat Arteriovenous Fistula. J Vasc Res. 2020;57:223-235 pubmed 出版商
Polley A, Khanam R, Sengupta A, Chakraborty S. Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro. Int J Cell Biol. 2020;2020:2045969 pubmed 出版商
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Martinez L, Robila V, Clark N, Du W, Idowu M, Rutkowski M, et al. Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer. Front Immunol. 2019;10:1942 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
Alpha-Smooth Muscle Actin Monoclonal Antibody (1A4), eFluor™ 570, eBioscience
目录# :
41-9760-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Immunohistochemistry: 1:100
物种 :
人类, 小鼠, 大鼠
克隆 :
1A4
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
Smooth Muscle Actin belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actin being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. In particular, smooth muscle actin is an alpha actin that is found in skeletal muscle. Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton. Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis. Smooth muscle actin is found on smooth muscle vessel walls, gut wall, myometrium, myoepithelial cells in breast and salivary glands. Defects in the smooth muscle actin gene cause aortic aneurysm familial thoracic type 6. Actin isoforms differ slightly in their N-terminus and the sequences of each are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown that smooth muscle actin appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases. Multiple alternatively spliced variants of smooth muscle actin have been identified.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Immunohistochemistry: 1:100
别名 :
0610041G09Rik; AAT6; ACT-4; acta2; acta2.L; acta2.S; actin; Actin Alpha 2 Smooth Muscle Aorta; actin alpha 2, smooth muscle; Actin Vascular Smooth Muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha 2, smooth muscle, aorta L homeolog; actin, alpha 2, smooth muscle, aorta S homeolog; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; ACTSA; ACTVS; alpha actin 2; Alpha Cardiac Actin; alpha smooth muscle actin; alpha-actin; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-SM-actin; alpha-smooth muscle actin; Aortic Smooth Muscle; ASMA; a-sma; cell growth-inhibiting gene 46 protein; GIG46; Growth Inhibiting Gene 46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, aortic smooth muscle; mymy5; SM actin; sma; SMactin; sm-actin; SMalphaA; smooth muscle; smooth muscle alpha-actin; vascular smooth muscle alpha-actin; wu:fb63d03; XELAEV_18034370mg
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国