产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
K-Ras Monoclonal Antibody (9.13)
目录 :
415700
规格 :
100微克
价格 :
375美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
9.13
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 3
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Kopp F, Wagner E, Roidl A. The proto-oncogene KRAS is targeted by miR-200c. Oncotarget. 2014;5:185-95 pubmed
Wong G, Zhou J, Liu J, Wu Z, Xu X, Li T, et al. Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition. Nat Med. 2018;24:968-977 pubmed 出版商
Kamerkar S, LeBleu V, Sugimoto H, Yang S, Ruivo C, Melo S, et al. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. 2017;546:498-503 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
K-Ras Monoclonal Antibody (9.13)
目录# :
415700
规格 :
100微克
价格 :
375美元
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 5 µg, Western Blot: 1-2 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
9.13
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
K-RAS (GTPase KRas) belongs to the Ras oncogene family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. It plays an important role in the regulation of cell proliferation and has a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes in colorectal cancer cells in a ZNF304-dependent manner. Mutations in the gene can result in leukemia acute myelogenous, leukemia juvenile myelomonocytic, Noonan Syndrome, gastric cancer, and cardiofaciocutaneous syndrome 2.
免疫原 :
Peptide corresponding to amino acid residues from the C-terminal of human K-Ras protein.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: 5 µg, Western Blot: 1-2 µg/mL
别名 :
AI929937; cellular c-Ki-ras2; cellular c-Ki-ras2 proto-oncogene; CFC2; c-Ki-ras; c-Kirsten-ras protein; c-Kirsten-ras proto-oncogene; C-K-RAS; c-K-ras2 protein; GTPase KRas; GTPase KRas, N-terminally processed; K RAS; Ki-ras; Kirsten rat sarcoma oncogene 2, expressed; Kirsten rat sarcoma viral oncogene; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral oncogene homologue 2 (active); KRAS; K-ras; K-Ras 2; K-ras p21 protein; KRAS proto-oncogene, GTPase; KRAS1; Kras2; Kras-2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NS; NS3; oncogene KRAS2; p21; p21 protein; p21B; PR310 c-K-ras oncogene; RALD; ras; RASK; RASK2; transforming protein p21; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国