产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
NR5A1单克隆抗体(N1665)
目录 :
434200
规格 :
100微升
价格 :
美国556.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
N1665
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 17
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:300; 图 1a
Russell J, Lim X, Santambrogio A, Yianni V, Kemkem Y, Wang B, et al. Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells. elife. 2021;10: pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 5b
Haston S, Pozzi S, Carreno G, Manshaei S, Panousopoulos L, González Meljem J, et al. MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma. Development. 2017;144:2141-2152 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 2a
Buonocore F, Kühnen P, Suntharalingham J, Del Valle I, Digweed M, Stachelscheid H, et al. Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans. J Clin Invest. 2017;127:1700-1713 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200
Manojlović Gacić E, Skender Gazibara M, Popovic V, Soldatovic I, Boricic N, Raičević S, et al. Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study. Endocr Pathol. 2016;27:1-11 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 6
Lewis S, Hedman C, Ziegler T, Ricke W, Jorgensen J. Steroidogenic factor 1 promotes aggressive growth of castration-resistant prostate cancer cells by stimulating steroid synthesis and cell proliferation. Endocrinology. 2014;155:358-69 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Kuhn E, Ayhan A, Shih I, Seidman J, Kurman R. Ovarian Brenner tumour: a morphologic and immunohistochemical analysis suggesting an origin from fallopian tube epithelium. Eur J Cancer. 2013;49:3839-49 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 6
Straume A, Løvås K, Miletic H, Gravdal K, Lønning P, Knappskog S. Elevated levels of the steroidogenic factor 1 are associated with over-expression of CYP19 in an oestrogen-producing testicular Leydig cell tumour. Eur J Endocrinol. 2012;166:941-9 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:200; 图 5
Ferraz de Souza B, Lin L, Shah S, Jina N, Hubank M, Dattani M, et al. ChIP-on-chip analysis reveals angiopoietin 2 (Ang2, ANGPT2) as a novel target of steroidogenic factor-1 (SF-1, NR5A1) in the human adrenal gland. FASEB J. 2011;25:1166-75 pubmed 出版商
Malolina E, Galiakberova A, Dashinimaev E, Kulibin A. Establishment of a pure culture of immature Sertoli cells by PDGFRA staining and cell sorting. Mol Reprod Dev. 2022;89:243-255 pubmed 出版商
Tjörnstrand A, Casar Borota O, Heurling K, Scholl M, Gjertsson P, Ragnarsson O, et al. Pre- and postoperative 68 Ga-DOTATOC positron emission tomography for hormone-secreting pituitary neuroendocrine tumours. Clin Endocrinol (Oxf). 2021;: pubmed 出版商
Hickman R, Bruce J, Otten M, Khandji A, Flowers X, Siegelin M, et al. Gonadotroph tumours with a low SF-1 labelling index are more likely to recur and are associated with enrichment of the PI3K-AKT pathway. Neuropathol Appl Neurobiol. 2021;47:415-427 pubmed 出版商
Fagan M, Ameroso D, Meng A, Rock A, Maguire J, Rios M. Essential and sex-specific effects of mGluR5 in ventromedial hypothalamus regulating estrogen signaling and glucose balance. Proc Natl Acad Sci U S A. 2020;117:19566-19577 pubmed 出版商
Tamanini J, Dal Fabbro M, de Freitas L, Vassallo J, de Souza Queiroz L, Rogerio F. Digital analysis of hormonal immunostaining in pituitary adenomas classified according to WHO 2017 criteria and correlation with preoperative laboratory findings. Neurosurg Focus. 2020;48:E12 pubmed 出版商
Janjic M, Prévide R, Fletcher P, Sherman A, Smiljanic K, Abebe D, et al. Divergent expression patterns of pituitary gonadotropin subunit and GnRH receptor genes to continuous GnRH in vitro and in vivo. Sci Rep. 2019;9:20098 pubmed 出版商
Osakabe M, Sato C, Suzuki M, Sugimoto R, Fujita Y, Uesugi N, et al. Mesenteric extraovarian Sertoli-Leydig cell tumor without DICER1 hotspot mutation: a case report. Diagn Pathol. 2019;14:27 pubmed 出版商
Portnoi M, Dumargne M, Rojo S, Witchel S, Duncan A, Eozenou C, et al. Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies. Hum Mol Genet. 2018;27:1228-1240 pubmed 出版商
Del Valle I, Buonocore F, Duncan A, Lin L, Barenco M, Parnaik R, et al. A genomic atlas of human adrenal and gonad development. Wellcome Open Res. 2017;2:25 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
NR5A1单克隆抗体(N1665)
目录# :
434200
规格 :
100微升
价格 :
美国556.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
ELISA: 0.1 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 3 µg/mL
物种 :
人类, 小鼠, 大鼠
克隆 :
N1665
抗体亚型 :
IgG1
储存 :
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
描述 :
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. SF-1 has been shown to be essential for fetal development of the hypothalamus, pituitary gland, gonads, and the adrenal gland. SF-1 has been shown to promote transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family. SF-1 contains two activation function domains, designated AF1 and AF2, common to many nuclear steroid receptors which have been shown to be necessary for interaction with other nuclear receptors as well as coactivators and corepressors including steroid receptor coactivator-1 (SRC-1), glucocorticoid receptor interacting protein 1 (GRIP1), cAMP response element binding protein (CREB) binding protein (CBP) and silencing mediator of retinoid acid and thyroid hormone receptor (SMRT).
免疫原 :
BALB/c mouse immunized with E.coli-expressed recombinant human SF-1 (218-461aa).
格式 :
液体
应用w/稀释 :
ELISA: 0.1 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 3 µg/mL
别名 :
Ad4BP; Ad4BP/SF-1; adrenal 4 binding protein; Adrenal 4 binding protein (AD4BP); adrenal 4-binding protein; ELP; ELP-3; Embryonal long terminal repeat-binding protein; embryonal LTR-binding protein; FTZ1; FTZF1; Ftz-F1; fushi tarazu 1 factor homolog; fushi tarazu factor homolog 1; Fushi tarazu factor homolog 1 (FTZ1); hSF-1; Nr5a1; nuclear receptor AdBP4; nuclear receptor subfamily 5 group A member 1; Nuclear receptor subfamily 5 group A member 1 (NR5A1); nuclear receptor subfamily 5, group A, member 1; POF7; SF1; SF-1; SPGF8; SRXY3; Steroid hormone receptor Ad4BP; steroid hydroxylase positive regulator; Steroidogenic factor 1; Steroidogenic factor 1 (SF1); steroidogenic factor 1 nuclear receptor; steroidogenic factor-1; STF1; STF-1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国