产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸甘油醛脱氢酶单克隆抗体(258)
目录 :
437000
规格 :
100微克
价格 :
375美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
258
反应物种 :
人类, 小鼠, , pigs , , 家羊, 国内马, 猕猴
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:10,000; 图 6a
Bodrug T, Wilson Kubalek E, Nithianantham S, Thompson A, Alfieri A, Gaska I, et al. The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 s2d
Soragni A, Janzen D, Johnson L, Lindgren A, Thai Quynh Nguyen A, Tiourin E, et al. A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas. Cancer Cell. 2016;29:90-103 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 7
Chaki S, Barhoumi R, Rivera G. Actin remodeling by Nck regulates endothelial lumen formation. Mol Biol Cell. 2015;26:3047-60 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10000
Stauch K, Purnell P, Fox H. Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability. J Proteome Res. 2014;13:2620-36 pubmed 出版商
  • 免疫印迹; 人类; 1:10000; 图 3
Villeneuve L, Tiede L, Morsey B, Fox H. Quantitative proteomics reveals oxygen-dependent changes in neuronal mitochondria affecting function and sensitivity to rotenone. J Proteome Res. 2013;12:4599-606 pubmed 出版商
  • 免疫印迹; 人类; 1:10000; 图 4
Chaki S, Barhoumi R, Berginski M, Sreenivasappa H, Trache A, Gomez S, et al. Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics. J Cell Sci. 2013;126:1637-49 pubmed 出版商
  • 免疫印迹; 猕猴
Delpeut S, Rudd P, Labonte P, von Messling V. Membrane fusion-mediated autophagy induction enhances morbillivirus cell-to-cell spread. J Virol. 2012;86:8527-35 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Hancock M, Hermanson S, Dolman N. A quantitative TR-FRET plate reader immunoassay for measuring autophagy. Autophagy. 2012;8:1227-44 pubmed 出版商
Marturano Kruik A, Villasante A, Yaeger K, Ambati S, Chramiec A, Raimondi M, et al. Biomechanical regulation of drug sensitivity in an engineered model of human tumor. Biomaterials. 2018;150:150-161 pubmed 出版商
Dhanjal N, Sharma S, Prabhu K, Prakash N. Selenium supplementation through Se-rich dietary matrices can upregulate the anti-inflammatory responses in lipopolysaccharide-stimulated murine macrophages. Food Agric Immunol. 2017;28:1374-1392 pubmed 出版商
Small J, Washburn E, Millington K, Zhu J, Holder S. The addition of abemaciclib to sunitinib induces regression of renal cell carcinoma xenograft tumors. Oncotarget. 2017;8:95116-95134 pubmed 出版商
Villasante A, Sakaguchi K, Kim J, Cheung N, Nakayama M, Parsa H, et al. Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma. Theranostics. 2017;7:4099-4117 pubmed 出版商
Villasante A, Marturano Kruik A, Ambati S, Liu Z, Godier Furnemont A, Parsa H, et al. Recapitulating the Size and Cargo of Tumor Exosomes in a Tissue-Engineered Model. Theranostics. 2016;6:1119-30 pubmed 出版商
Ratnikov B, Scott D, Osterman A, Smith J, Ronai Z. Metabolic rewiring in melanoma. Oncogene. 2017;36:147-157 pubmed 出版商
Purnell P, Fox H. Autophagy-mediated turnover of dynamin-related protein 1. BMC Neurosci. 2013;14:86 pubmed 出版商
Li Y, Lin L, Li Z, Ye X, Xiong K, Aryal B, et al. Iron homeostasis regulates the activity of the microRNA pathway through poly(C)-binding protein 2. Cell Metab. 2012;15:895-904 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
磷酸甘油醛脱氢酶单克隆抗体(258)
目录# :
437000
规格 :
100微克
价格 :
375美元
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Bovine, Equine, Feline, Human, Non-human primate, Ovine, Porcine
应用 :
Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: Assay Dependent, Western Blot: 1-2 µg/mL
物种 :
Bovine, Equine, Feline, Human, Non-human primate, Ovine, Porcine
克隆 :
258
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function. GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling. Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis and as part of the cellular phenotype of age-related neurodegenerative diseases. Further, GAPDH is involved in other cellular processes ranging from membrane fusion, and neuronal apoptosis in cancer. GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease (AD), and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease. Associations between GAPDH, actin and tubulin have also be reported. Since GAPDH is expressed at high levels in most tissues, it is useful as protein loading control in Western Blot analysis.
免疫原 :
Recombinant protein derived from the C-terminus region of human GAPDH protein
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: Assay Dependent, Western Blot: 1-2 µg/mL
别名 :
38 kDa BFA-dependent ADP-ribosylation substrate; aging-associated gene 9 protein; BARS-38; bb02e05; cb350; cb609; CDABP0047; EC 1.2.1.12; epididymis secretory protein Li 278; epididymis secretory sperm binding protein Li 162eP; fb71f08; fk58c09; G3PD; G3PDH; Gapd; GAPD2; gapdh; GAPDH2; GAPDH-2; GAPDHS; GAPDS; Gapd-s; glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde 3-phosphate dehydrogenase, testis-specific; glyceraldehyde phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; Glyceraldehyde-3-phosphate dehydrogenase 2; glyceraldehyde-3-phosphate dehydrogenase GAPDH; glyceraldehyde-3-phosphate dehydrogenase like-17 protein; glyceraldehyde-3-phosphate dehydrogenase type 2; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; glyceraldehyde-phosphate-dehydrogenase; glycerine aldehyde 3-phosphate dehydrogenase; HEL-S-162eP; HEL-S-278; HGNC:4141; HSD35; HSD-35; I79_001391; KNC-NDS6; LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase, testis-specific; mg:bb02e05; MGC128279 protein; MGC88685; OK/SW-cl.12; Peptidyl-cysteine S-nitrosylase GAPDH; similar to glyceraldehyde 3-phosphate dehydrogenase; spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase; Unknown (protein for IMAGE:8101613); wu:fb33a10; wu:fb71f08; wu:fk58c09; wu:ft80f05; zgc:76908
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国