| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
- 免疫细胞化学; 犬; 图 1e
- 免疫印迹; 犬; 图 s1d
| Kajiwara K, Yamano S, Aoki K, Okuzaki D, Matsumoto K, Okada M. CDCP1 promotes compensatory renal growth by integrating Src and Met signaling. Life Sci Alliance. 2021;4: pubmed 出版商 |
| Smith R, Ninchoji T, Gordon E, André H, Dejana E, Vestweber D, et al. Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin. elife. 2020;9: pubmed 出版商 |
| Jin L, Chun J, Pan C, Alesi G, Li D, Magliocca K, et al. Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis. Oncogene. 2017;36:3797-3806 pubmed 出版商 |
- 免疫组化; fruit fly ; 1:100; 图 2r
| Bangi E, Murgia C, Teague A, Sansom O, Cagan R. Functional exploration of colorectal cancer genomes using Drosophila. Nat Commun. 2016;7:13615 pubmed 出版商 |
| Sun L, Pan J, Yu L, Liu H, Shu X, Sun L, et al. Tumor endothelial cells promote metastasis and cancer stem cell-like phenotype through elevated Epiregulin in esophageal cancer. Am J Cancer Res. 2016;6:2277-2288 pubmed |
| Belliard A, Gulati G, Duan Q, Alves R, Brewer S, Madan N, et al. Ischemia/reperfusion-induced alterations of enzymatic and signaling functions of the rat cardiac Na+/K+-ATPase: protection by ouabain preconditioning. Physiol Rep. 2016;4: pubmed |
| Egholm C, Khammy M, Dalsgaard T, Mazur A, Tritsaris K, Hansen A, et al. GLP-1 inhibits VEGFA-mediated signaling in isolated human endothelial cells and VEGFA-induced dilation of rat mesenteric arteries. Am J Physiol Heart Circ Physiol. 2016;311:H1214-H1224 pubmed 出版商 |
| Gross S, Devraj K, Feng Y, Macas J, Liebner S, Wieland T. Nucleoside diphosphate kinase B regulates angiogenic responses in the endothelium via caveolae formation and c-Src-mediated caveolin-1 phosphorylation. J Cereb Blood Flow Metab. 2017;37:2471-2484 pubmed 出版商 |
| Barcus C, Keely P, Eliceiri K, Schuler L. Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells. Oncotarget. 2016;7:48093-48106 pubmed 出版商 |
| Blas Rus N, Bustos Morán E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, et al. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun. 2016;7:11389 pubmed 出版商 |
| Levine B, Cagan R. Drosophila Lung Cancer Models Identify Trametinib plus Statin as Candidate Therapeutic. Cell Rep. 2016;14:1477-1487 pubmed 出版商 |
| Couderc C, Boin A, Fuhrmann L, Vincent Salomon A, Mandati V, Kieffer Y, et al. AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin. Neoplasia. 2016;18:10-24 pubmed 出版商 |
| Peckham H, Giuffrida L, Wood R, Gonsalvez D, Ferner A, Kilpatrick T, et al. Fyn is an intermediate kinase that BDNF utilizes to promote oligodendrocyte myelination. Glia. 2016;64:255-69 pubmed 出版商 |
| Kozlova N, Samoylenko A, Drobot L, Kietzmann T. Urokinase is a negative modulator of Egf-dependent proliferation and motility in the two breast cancer cell lines MCF-7 and MDA-MB-231. Mol Carcinog. 2016;55:170-81 pubmed 出版商 |
| Goob G, Adrian J, Cossu C, Hauck C. Phagocytosis mediated by the human granulocyte receptor CEACAM3 is limited by the receptor-type protein tyrosine phosphatase PTPRJ. J Biol Chem. 2022;298:102269 pubmed 出版商 |
| Lai Y, Chang H, Chen H, Chang G, Chen J. Peruvoside is a novel Src inhibitor that suppresses NSCLC cell growth and motility by downregulating multiple Src-EGFR-related pathways. Am J Cancer Res. 2022;12:2576-2593 pubmed |
| Staehr C, Rohde P, Krarup N, Ringgaard S, Laustsen C, Johnsen J, et al. Migraine-Associated Mutation in the Na,K-ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function. J Am Heart Assoc. 2022;11:e021814 pubmed 出版商 |
| Enomoto M, Takemoto D, Igaki T. Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila. Dev Cell. 2021;56:2223-2236.e5 pubmed 出版商 |
| Ninchoji T, Love D, Smith R, Hedlund M, Vestweber D, Sessa W, et al. eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin. elife. 2021;10: pubmed 出版商 |
| Aldaz P, Auzmendi Iriarte J, Durantez M, Lasheras Otero I, Carrasco Garcia E, Zelaya M, et al. Identification of a Dexamethasone Mediated Radioprotection Mechanism Reveals New Therapeutic Vulnerabilities in Glioblastoma. Cancers (Basel). 2021;13: pubmed 出版商 |
| Fang R, Chen X, Zhang S, Shi H, Ye Y, Shi H, et al. EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma. Nat Commun. 2021;12:177 pubmed 出版商 |
| Nagano T, Iwasaki T, Onishi K, Awai Y, Terachi A, Kuwaba S, et al. LY6D-induced macropinocytosis as a survival mechanism of senescent cells. J Biol Chem. 2021;296:100049 pubmed 出版商 |
| Markov A, Fedorova A, Kravtsova V, Bikmurzina A, Okorokova L, Matchkov V, et al. Circulating Ouabain Modulates Expression of Claudins in Rat Intestine and Cerebral Blood Vessels. Int J Mol Sci. 2020;21: pubmed 出版商 |
| Sorrentino G, Perino A, Yıldız E, El Alam G, Bou Sleiman M, Gioiello A, et al. Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration. Gastroenterology. 2020;159:956-968.e8 pubmed 出版商 |
| Rambur A, Lours Calet C, Beaudoin C, Buñay J, Vialat M, Mirouse V, et al. Sequential Ras/MAPK and PI3K/AKT/mTOR pathways recruitment drives basal extrusion in the prostate-like gland of Drosophila. Nat Commun. 2020;11:2300 pubmed 出版商 |
| Schimmel L, Fukuhara D, Richards M, Jin Y, Essebier P, Frampton E, et al. c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly. Development. 2020;147: pubmed 出版商 |
| Montagner M, Bhome R, Hooper S, Chakravarty P, Qin X, Sufi J, et al. Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination. Nat Cell Biol. 2020;22:289-296 pubmed 出版商 |
| Hara T, Kimura A, Miyazaki T, Tanaka H, Morimoto M, Nakai K, et al. Cabozantinib inhibits AXL- and MET-dependent cancer cell migration induced by growth-arrest-specific 6 and hepatocyte growth factor. Biochem Biophys Rep. 2020;21:100726 pubmed 出版商 |
| Izquierdo I, Barrachina M, Hermida Nogueira L, Casas V, Morán L, Lacerenza S, et al. A Comprehensive Tyrosine Phosphoproteomic Analysis Reveals Novel Components of the Platelet CLEC-2 Signaling Cascade. Thromb Haemost. 2020;120:262-276 pubmed 出版商 |
| Jain P, Guerreiro P, Canato S, Janody F. The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis. Sci Rep. 2019;9:19843 pubmed 出版商 |
| Hermida Prado F, Granda Díaz R, Del Río Ibisate N, Villaronga M, Allonca E, Garmendia I, et al. The Differential Impact of SRC Expression on the Prognosis of Patients with Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2019;11: pubmed 出版商 |
| Li Y, Jiang G, Chen L, Jiang Y, Jiao J. Formin mDia1 contributes to migration and epithelial-mesenchymal transition of tubular epithelial cells exposed to TGF-β1. J Cell Biochem. 2020;121:3861-3870 pubmed 出版商 |
| Valcarcel Jimenez L, Macchia A, Crosas Molist E, Schaub Clerigué A, Camacho L, Martin Martin N, et al. PGC1α Suppresses Prostate Cancer Cell Invasion through ERRα Transcriptional Control. Cancer Res. 2019;79:6153-6165 pubmed 出版商 |
| Dong G, Lin X, Liu H, Gao D, Cui J, Ren Z, et al. Intermittent hypoxia alleviates increased VEGF and pro-angiogenic potential in liver cancer cells. Oncol Lett. 2019;18:1831-1839 pubmed 出版商 |
| Huang Y, Zhou B, Nabet A, Wernig M, Sudhof T. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk. J Neurosci. 2019;39:7408-7427 pubmed 出版商 |
| Yan Y, Wang J, Chaudhry M, Nie Y, Sun S, Carmon J, et al. Metabolic Syndrome and Salt-Sensitive Hypertension in Polygenic Obese TALLYHO/JngJ Mice: Role of Na/K-ATPase Signaling. Int J Mol Sci. 2019;20: pubmed 出版商 |
| Chen Y, Ou M, Fang C, Lee T, Tzeng S. High Glucose Concentrations Negatively Regulate the IGF1R/Src/ERK Axis through the MicroRNA-9 in Colorectal Cancer. Cells. 2019;8: pubmed 出版商 |
| Mettu N, Niedzwiecki D, Rushing C, Nixon A, Jia J, Haley S, et al. A phase I study of gemcitabine + dasatinib (gd) or gemcitabine + dasatinib + cetuximab (GDC) in refractory solid tumors. Cancer Chemother Pharmacol. 2019;83:1025-1035 pubmed 出版商 |
| Nichols E, Smith C. Pioneer axons employ Cajal's battering ram to enter the spinal cord. Nat Commun. 2019;10:562 pubmed 出版商 |
| Elbediwy A, Vanyai H, Díaz de la Loza M, Frith D, Snijders A, Thompson B. Enigma proteins regulate YAP mechanotransduction. J Cell Sci. 2018;131: pubmed 出版商 |
| Tsukamoto T, Kajiwara K, Nada S, Okada M. Src mediates TGF-β-induced intraocular pressure elevation in glaucoma. J Cell Physiol. 2019;234:1730-1744 pubmed 出版商 |
| Dandoulaki M, Petsalaki E, Sumpton D, Zanivan S, Zachos G. Src activation by Chk1 promotes actin patch formation and prevents chromatin bridge breakage in cytokinesis. J Cell Biol. 2018;217:3071-3089 pubmed 出版商 |
| Drummond C, Fan X, Haller S, Kennedy D, Liu J, Tian J. Na/K-ATPase signaling mediates miR-29b-3p regulation and cardiac fibrosis formation in mice with chronic kidney disease. PLoS ONE. 2018;13:e0197688 pubmed 出版商 |
| Hoch Kraft P, White R, Tenzer S, Krämer Albers E, Trotter J, Gonsior C. Dual role of the RNA helicase DDX5 in post-transcriptional regulation of myelin basic protein in oligodendrocytes. J Cell Sci. 2018;131: pubmed 出版商 |
| Maxson M, Naj X, O Meara T, Plumb J, Cowen L, Grinstein S. Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes. elife. 2018;7: pubmed 出版商 |
| Takada M, Parys M, Gregory Bryson E, Vilar Saavedra P, Kiupel M, Yuzbasiyan Gurkan V. A novel canine histiocytic sarcoma cell line: initial characterization and utilization for drug screening studies. BMC Cancer. 2018;18:237 pubmed 出版商 |
| Sonoshita M, Scopton A, Ung P, Murray M, Silber L, Maldonado A, et al. A whole-animal platform to advance a clinical kinase inhibitor into new disease space. Nat Chem Biol. 2018;14:291-298 pubmed 出版商 |
| Mayoral Varo V, Calcabrini A, Sanchez Bailon M, Martin Perez J. miR205 inhibits stem cell renewal in SUM159PT breast cancer cells. PLoS ONE. 2017;12:e0188637 pubmed 出版商 |
| He F, Soriano P. Dysregulated PDGFRα signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification. Development. 2017;144:4026-4036 pubmed 出版商 |
| Perea D, Guiu J, Hudry B, Konstantinidou C, Milona A, Hadjieconomou D, et al. Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia. EMBO J. 2017;36:3029-3045 pubmed 出版商 |
| Govaere O, Petz M, Wouters J, Vandewynckel Y, Scott E, Topal B, et al. The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma. Oncogene. 2017;36:6605-6616 pubmed 出版商 |
| Renault Mihara F, Mukaino M, Shinozaki M, Kumamaru H, Kawase S, Baudoux M, et al. Regulation of RhoA by STAT3 coordinates glial scar formation. J Cell Biol. 2017;216:2533-2550 pubmed 出版商 |
| Tavares S, Vieira A, Taubenberger A, Araújo M, Martins N, Bras Pereira C, et al. Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells. Nat Commun. 2017;8:15237 pubmed 出版商 |
| Kemmerling N, Wunderlich P, Theil S, Linnartz Gerlach B, Hersch N, Hoffmann B, et al. Intramembranous processing by ?-secretase regulates reverse signaling of ephrin-B2 in migration of microglia. Glia. 2017;65:1103-1118 pubmed 出版商 |
| Leyme A, Marivin A, Garcia Marcos M. GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Creates a Positive Feedback Loop That Potentiates Outside-in Integrin Signaling in Cancer Cells. J Biol Chem. 2016;291:8269-82 pubmed 出版商 |
| Drummond C, Hill M, Shi H, Fan X, Xie J, Haller S, et al. Na/K-ATPase signaling regulates collagen synthesis through microRNA-29b-3p in cardiac fibroblasts. Physiol Genomics. 2016;48:220-9 pubmed 出版商 |
| Andersson L, Scharin Täng M, Lundqvist A, Lindbom M, Mardani I, Fogelstrand P, et al. Rip2 modifies VEGF-induced signalling and vascular permeability in myocardial ischaemia. Cardiovasc Res. 2015;107:478-86 pubmed 出版商 |
| Fukumoto M, Kurisu S, Yamada T, Takenawa T. α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation. PLoS ONE. 2015;10:e0120616 pubmed 出版商 |
| Kwon H, Lee J, Jeong K, Jang D, Pak Y. Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation. Biochim Biophys Acta. 2015;1853:1022-34 pubmed 出版商 |
| Shaw A, Pickup M, Chytil A, Aakre M, Owens P, Moses H, et al. TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. PLoS ONE. 2015;10:e0117908 pubmed 出版商 |
| Barcus C, Holt E, Keely P, Eliceiri K, Schuler L. Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells. PLoS ONE. 2015;10:e0116891 pubmed 出版商 |
| Girotti M, Lopes F, Preece N, Niculescu Duvaz D, Zambon A, Davies L, et al. Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma. Cancer Cell. 2015;27:85-96 pubmed 出版商 |
| Cunnick J, Kim S, Hadsell J, Collins S, Cerra C, Reiser P, et al. Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland. Oncogene. 2015;34:2640-9 pubmed 出版商 |
