产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化CDK1(Thr14, Tyr15)多克隆抗体
目录 :
44-686G
规格 :
100微升
价格 :
美国425.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
文章摘录数: 7
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 5
Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed 出版商
Baqai U, Purwin T, Bechtel N, Chua V, Han A, Hartsough E, et al. Multi-omics profiling shows BAP1 loss is associated with upregulated cell adhesion molecules in uveal melanoma. Mol Cancer Res. 2022;: pubmed 出版商
Hashimoto Y, Tanaka H. Mre11 exonuclease activity promotes irreversible mitotic progression under replication stress. Life Sci Alliance. 2022;5: pubmed 出版商
Moretti F, Giardino G, Attenborough T, Gkazi A, Margetts B, la Marca G, et al. Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy. Sci Rep. 2021;11:23221 pubmed 出版商
Hashimoto Y, Tanaka H. Ongoing replication forks delay the nuclear envelope breakdown upon mitotic entry. J Biol Chem. 2021;296:100033 pubmed 出版商
Lapadula D, Farias E, Randolph C, Purwin T, McGrath D, Charpentier T, et al. Effects of Oncogenic Gαq and Gα11 Inhibition by FR900359 in Uveal Melanoma. Mol Cancer Res. 2019;17:963-973 pubmed 出版商
Bana E, Sibille E, Valente S, Cerella C, Chaimbault P, Kirsch G, et al. A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death. Mol Carcinog. 2015;54:229-41 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
磷酸化CDK1(Thr14, Tyr15)多克隆抗体
目录# :
44-686G
规格 :
100微升
价格 :
美国425.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.
免疫原 :
The antibody was produced against a synthetic phosphopeptide derived from the region of the human cyclin-dependent kinase that contains threonine 14 and tyrosine 15.
格式 :
液体
应用w/稀释 :
Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
别名 :
5363; ABL1; cdc; CDC2; cdc-2; cdc2 kinase; CDC28A; Cdc2a; cdc2-a; cdc2Dm; cdc2x1.1; CDCDm; CDK1; Cdk-1; cdk1.S; CDK1/CDC2; CDK1-A; cdk1-b; Cdk1-PA; CDKN1; cell cycle controller CDC2; cell cycle p34 CDC2 kinase protein; cell division control; cell division control protein 2 homolog; Cell division control protein 2 homolog 1; cell division control protein 2-A; cell division cycle 2 homolog A; cell division cycle 2 like; cell division cycle 2, G1 to S and G2 to M; Cell division cycle control protein 2; cell division cycle control protein 2a; cell division protein kinase 1; Cell division protein kinase 1-A; CG5363; CG5363-PA; cyclin dependent kinase; cyclin dependent kinase 1; cyclin-dependent kinase; Cyclin-dependent kinase 1; cyclin-dependent kinase 1 S homeolog; cyclin-dependent kinase 1-A; D2366; Dcdc2; dCdk1; DKFZp686L20222; Dm cdc2; Dmcdc2; DmCdk1; Dmel CG5363; Dmel_CG5363; DNA polymerase delta catalytic subunit; DNA polymerase III; DNA-directed DNA polymerase delta POL3; group 4; HPR6; KCIP-1; l(2)31Eh; LD38718p; maturation-promoting factor; MGC111195; MGC53829; MPF; OTTHUMP00000019660; P34 CDK1; P34 MGC111195; p34 protein kinase; p34 protein kinase 1; p34 ; p34cdc2; p34-cdc2 homologue; POL3; Protein 1054; protein 2; PSTAIR; TEX1; unnamed protein product; xcdc2; XELAEV_18036802mg; YDL102W
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国