产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Phospho-Paxillin (Tyr31) Polyclonal Antibody
目录 :
44-720G
规格 :
100微升
价格 :
美国425.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:100; 图 4a
Haroon M, Boers H, Bakker A, Bloks N, Hoogaars W, Giordani L, et al. Reduced growth rate of aged muscle stem cells is associated with impaired mechanosensitivity. Aging (Albany NY). 2022;14:28-53 pubmed 出版商
  • 免疫印迹; 人类; 图 s1d
Nava M, Miroshnikova Y, Biggs L, Whitefield D, Metge F, Boucas J, et al. Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage. Cell. 2020;181:800-817.e22 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3b
Wu Y, Jhao Y, Cheng Y, Chen Y. 15-Deoxy-?12,14-prostaglandin J2 inhibits migration of human thyroid carcinoma cells by disrupting focal adhesion complex and adherens junction. Oncol Lett. 2017;13:2569-2576 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400; 图 s3
Kumar A, Ouyang M, van den Dries K, McGhee E, Tanaka K, Anderson M, et al. Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity. J Cell Biol. 2016;213:371-83 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Marcos Ramiro B, García Weber D, Barroso S, Feito J, Ortega M, Cernuda Morollón E, et al. RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border. J Cell Biol. 2016;213:385-402 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 5
  • 免疫印迹; 小鼠; 图 5
Rooney N, Wang P, Brennan K, Gilmore A, Streuli C. The Integrin-Mediated ILK-Parvin-?Pix Signaling Axis Controls Differentiation in Mammary Epithelial Cells. J Cell Physiol. 2016;231:2408-17 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 5
Kraft Sheleg O, Zaffryar Eilot S, Genin O, Yaseen W, Soueid Baumgarten S, Kessler O, et al. Localized LoxL3-Dependent Fibronectin Oxidation Regulates Myofiber Stretch and Integrin-Mediated Adhesion. Dev Cell. 2016;36:550-61 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed 出版商
Xue Q, Varady S, Waddell T, Roman M, CARRINGTON J, Roh Johnson M. Lack of Paxillin phosphorylation promotes single-cell migration in vivo. J Cell Biol. 2023;222: pubmed 出版商
Bousgouni V, Inge O, Robertson D, Jones I, Clatworthy I, Bakal C. ARHGEF9 regulates melanoma morphogenesis in environments with diverse geometry and elasticity by promoting filopodial-driven adhesion. iScience. 2022;25:104795 pubmed 出版商
Guo Y, Mei F, Huang Y, Ma S, Wei Y, Zhang X, et al. Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-YAP signaling axis. Bioact Mater. 2022;7:364-376 pubmed 出版商
Tilve S, Iweka C, Bao J, Hawken N, Mencio C, Geller H. Phospholipid phosphatase related 1 (PLPPR1) increases cell adhesion through modulation of Rac1 activity. Exp Cell Res. 2020;389:111911 pubmed 出版商
Lu J, Doyle A, Shinsato Y, Wang S, Bodendorfer M, Zheng M, et al. Basement Membrane Regulates Fibronectin Organization Using Sliding Focal Adhesions Driven by a Contractile Winch. Dev Cell. 2020;52:631-646.e4 pubmed 出版商
Verstappen J, Jin J, Kocer G, Haroon M, Jonkheijm P, Bakker A, et al. RGD-functionalized supported lipid bilayers modulate pre-osteoblast adherence and promote osteogenic differentiation. J Biomed Mater Res A. 2020;108:923-937 pubmed 出版商
Jaumouillé V, Cartagena Rivera A, Waterman C. Coupling of β2 integrins to actin by a mechanosensitive molecular clutch drives complement receptor-mediated phagocytosis. Nat Cell Biol. 2019;21:1357-1369 pubmed 出版商
Rezey A, Gerlach B, Wang R, Liao G, Tang D. Plk1 Mediates Paxillin Phosphorylation (Ser-272), Centrosome Maturation, and Airway Smooth Muscle Layer Thickening in Allergic Asthma. Sci Rep. 2019;9:7555 pubmed 出版商
Rahikainen R, Ohman T, Turkki P, Varjosalo M, Hytönen V. Talin-mediated force transmission and talin rod domain unfolding independently regulate adhesion signaling. J Cell Sci. 2019;: pubmed 出版商
Iwasawa T, Zhang P, Ohkawa Y, Momota H, Wakabayashi T, Ohmi Y, et al. Enhancement of malignant properties of human glioma cells by ganglioside GD3/GD2. Int J Oncol. 2018;52:1255-1266 pubmed 出版商
Yang X, Mei S, Niu H, Li J. Nicotinic acid impairs assembly of leading edge in glioma cells. Oncol Rep. 2017;38:829-836 pubmed 出版商
Wu J, Chen Y, Kuo C, Wenshin Yu H, Chen Y, Chiou A, et al. Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration. Sci Rep. 2015;5:18476 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
Phospho-Paxillin (Tyr31) Polyclonal Antibody
目录# :
44-720G
规格 :
100微升
价格 :
美国425.00
克隆性 :
多克隆
纯度 :
亲和色谱
宿主 :
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 1:250, Immunohistochemistry: Assay-dependent, Western Blot: 1:1,000
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
免疫原 :
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human paxillin that contains tyrosine 31.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:250, Immunohistochemistry: Assay-dependent, Western Blot: 1:1,000
别名 :
adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国