产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化PKC甲(Thr638)多克隆抗体
目录 :
44-962G
规格 :
100微升
价格 :
美国475.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
文章摘录数: 4
参考文献
Bhandari D, Elshaarrawi A, Katula K. The human WNT5A isoforms display similar patterns of expression but distinct and overlapping activities in normal human osteoblasts. J Cell Biochem. 2021;: pubmed 出版商
Randles M, Lausecker F, Humphries J, Byron A, Clark S, Miner J, et al. Basement membrane ligands initiate distinct signalling networks to direct cell shape. Matrix Biol. 2020;90:61-78 pubmed 出版商
Bizzarro V, Belvedere R, Pessolano E, Parente L, Petrella F, Perretti M, et al. Mesoglycan induces keratinocyte activation by triggering syndecan-4 pathway and the formation of the annexin A1/S100A11 complex. J Cell Physiol. 2019;234:20174-20192 pubmed 出版商
Ray P, Chin A, Worley K, Fan J, Kaur G, Wu M, et al. Intrinsic cellular chirality regulates left-right symmetry breaking during cardiac looping. Proc Natl Acad Sci U S A. 2018;115:E11568-E11577 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
磷酸化PKC甲(Thr638)多克隆抗体
目录# :
44-962G
规格 :
100微升
价格 :
美国475.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:250, Western Blot: 1:1,000
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
The PKC family of serine/threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. Protein kinase C (PKC) can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
免疫原 :
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human PKC that contains threonine 638. The sequence is conserved in mouse and rat.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:250, Western Blot: 1:1,000
别名 :
AAG6; aging-associated gene 6; AI875142; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; Pkca; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; Prkca; prkcaa; protein kinase C; protein kinase C alpha; protein kinase C alpha type; protein kinase C alpha type; protein kinase C, alpha, a; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045); unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国