产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
SDHB单克隆抗体(21A11AE7)
目录 :
459230
规格 :
100微克
价格 :
美国456
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
21A11AE7
反应物种 :
中国人仓鼠, 人类, 小鼠, 大鼠, 牛, pigs , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:500; 图 4b
Dai D, Danoviz M, Wiczer B, Laflamme M, Tian R. Mitochondrial Maturation in Human Pluripotent Stem Cell Derived Cardiomyocytes. Stem Cells Int. 2017;2017:5153625 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Gali Ramamoorthy T, Laverny G, Schlagowski A, Zoll J, Messaddeq N, Bornert J, et al. The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles. Nat Commun. 2015;6:10210 pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000
Perdomini M, Belbellaa B, Monassier L, Reutenauer L, Messaddeq N, Cartier N, et al. Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia. Nat Med. 2014;20:542-7 pubmed 出版商
  • 免疫印迹; 大鼠; 图 9
Dun Y, Vargas J, Brot N, Finnemann S. Independent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells. Free Radic Biol Med. 2013;65:1340-1351 pubmed 出版商
  • 免疫印迹; 人类; 图 11
Bancos I, Bida J, Tian D, Bundrick M, John K, Holte M, et al. High-throughput screening for growth inhibitors using a yeast model of familial paraganglioma. PLoS ONE. 2013;8:e56827 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Kim S, Asaka M, Higashida K, Takahashi Y, Holloszy J, Han D. ?-Adrenergic stimulation does not activate p38 MAP kinase or induce PGC-1? in skeletal muscle. Am J Physiol Endocrinol Metab. 2013;304:E844-52 pubmed 出版商
Van Haute L, Hendrick A, D Souza A, Powell C, Rebelo Guiomar P, Harbour M, et al. METTL15 introduces N4-methylcytidine into human mitochondrial 12S rRNA and is required for mitoribosome biogenesis. Nucleic Acids Res. 2019;47:10267-10281 pubmed 出版商
Jia Y, Liu N, Viswakarma N, Sun R, Schipma M, Shang M, et al. PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism. Int J Mol Sci. 2018;19: pubmed 出版商
Barrasso A, Tong X, Poche R. The mito::mKate2 mouse: A far-red fluorescent reporter mouse line for tracking mitochondrial dynamics in vivo. Genesis. 2018;56: pubmed 出版商
Lin A, Abbas S, Kim S, Ortega M, Bouamar H, Escobedo Y, et al. D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2. Nat Commun. 2015;6:7768 pubmed 出版商
Morató L, Ruiz M, Boada J, Calingasan N, Galino J, Guilera C, et al. Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy. Cell Death Differ. 2015;22:1742-53 pubmed 出版商
Ussakli C, Ebaee A, Binkley J, Brentnall T, Emond M, Rabinovitch P, et al. Mitochondria and tumor progression in ulcerative colitis. J Natl Cancer Inst. 2013;105:1239-48 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
SDHB单克隆抗体(21A11AE7)
目录# :
459230
规格 :
100微克
价格 :
美国456
克隆性 :
单克隆
纯度 :
IgG分馏成分
宿主 :
小鼠
反应物种 :
牛, 仓鼠, 人类, 小鼠, 猪, 大鼠, 斑马鱼
应用 :
Flow Cytometry: 1 µg per 10^6 cells, Immunocytochemistry: 1 µg/ml, Immunohistochemistry: Assay-dependent, Western Blot: 5 µg/mL
物种 :
牛, 仓鼠, 人类, 小鼠, 猪, 大鼠, 斑马鱼
克隆 :
21A11AE7
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
免疫原 :
Bovine Heart Complex II, with traces of Complex III.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg per 10^6 cells, Immunocytochemistry: 1 µg/ml, Immunohistochemistry: Assay-dependent, Western Blot: 5 µg/mL
别名 :
0710008N11Rik; CWS2; fj46d06; FLJ92337; I79_022285; Ip; iron-sulfur subunit; iron-sulfur subunit of complex II; OTTHUMP00000044624; PGL4; SDH; SDH1; SDH2; Sdhb; SDHB protein; SDHB; sdhB; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex iron sulfur subunit B; succinate dehydrogenase complex subunit B; succinate dehydrogenase complex subunit B, iron sulfur (Ip); succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate dehydrogenase Ip subunit; succinate dehydrogenase iron-protein subunit; wu:fj46d06
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国