产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), PerCP-eFluor™ 710, eBioscience
目录 :
46-0411-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
Percp/efluor 710
克隆名称 :
eBioMWReg30(MWReg30)
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 75
参考文献
Cardenas R, Gonzalez R, Sanchez E, Ramos M, Cardenas E, Rodarte A, et al. SNAP23 is essential for platelet and mast cell development and required in connective tissue mast cells for anaphylaxis. J Biol Chem. 2021;296:100268 pubmed 出版商
Shvartsman M, Bilican S, Lancrin C. Iron deficiency disrupts embryonic haematopoiesis but not the endothelial to haematopoietic transition. Sci Rep. 2019;9:6414 pubmed 出版商
Soukup A, Zheng Y, Mehta C, Wu J, Liu P, Cao M, et al. Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer. J Clin Invest. 2019;129:1180-1192 pubmed 出版商
Wang X, Dong F, Zhang S, Yang W, Yu W, Wang Z, et al. TGF-?1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells. Stem Cell Reports. 2018;11:274-287 pubmed 出版商
Bergiers I, Andrews T, Vargel Bölükbaşı Ö, Buness A, Janosz E, Lopez Anguita N, et al. Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis. elife. 2018;7: pubmed 出版商
Nitulescu I, Meyer S, Wen Q, Crispino J, Lemieux M, Levine R, et al. Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation. EBioMedicine. 2017;26:112-125 pubmed 出版商
Alzubi J, Pallant C, Mussolino C, Howe S, Thrasher A, Cathomen T. Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model. Sci Rep. 2017;7:12475 pubmed 出版商
Bernitz J, Kim H, MacArthur B, SIEBURG H, Moore K. Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions. Cell. 2016;167:1296-1309.e10 pubmed 出版商
Jin Q, Ren Y, Wang M, Suraneni P, Li D, Crispino J, et al. Novel function of FAXDC2 in megakaryopoiesis. Blood Cancer J. 2016;6:e478 pubmed 出版商
Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed 出版商
Illendula A, Gilmour J, Grembecka J, Tirumala V, Boulton A, Kuntimaddi A, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. EBioMedicine. 2016;8:117-131 pubmed 出版商
Chen I, Caprioli A, Ohnuki H, Kwak H, Porcher C, Tosato G. EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta. Sci Rep. 2016;6:27195 pubmed 出版商
Liu H, Zhang A, Xu J, Chen Y, Zhu Y. H2S protects against fatal myelosuppression by promoting the generation of megakaryocytes/platelets. J Hematol Oncol. 2016;9:13 pubmed 出版商
Vargel O, Zhang Y, Kosim K, Ganter K, Foehr S, Mardenborough Y, et al. Activation of the TGFβ pathway impairs endothelial to haematopoietic transition. Sci Rep. 2016;6:21518 pubmed 出版商
Ghanem L, Kromer A, Silverman I, Chatterji P, Traxler E, Penzo Méndez A, et al. The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development. Mol Cell Biol. 2016;36:304-19 pubmed 出版商
Clarke R, Robitaille A, Moon R, Keller G. A Quantitative Proteomic Analysis of Hemogenic Endothelium Reveals Differential Regulation of Hematopoiesis by SOX17. Stem Cell Reports. 2015;5:291-304 pubmed 出版商
Beaulieu L, Clancy L, Tanriverdi K, Benjamin E, Kramer C, Weinberg E, et al. Specific Inflammatory Stimuli Lead to Distinct Platelet Responses in Mice and Humans. PLoS ONE. 2015;10:e0131688 pubmed 出版商
Ditadi A, Sturgeon C, Tober J, Awong G, Kennedy M, Yzaguirre A, et al. Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages. Nat Cell Biol. 2015;17:580-91 pubmed 出版商
Bruns I, Lucas D, Pinho S, Ahmed J, Lambert M, Kunisaki Y, et al. Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion. Nat Med. 2014;20:1315-20 pubmed 出版商
Wilkinson A, Kawata V, Schütte J, Gao X, Antoniou S, Baumann C, et al. Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification. Development. 2014;141:4018-30 pubmed 出版商
Liakhovitskaia A, Rybtsov S, Smith T, Batsivari A, Rybtsova N, Rode C, et al. Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this. Development. 2014;141:3319-23 pubmed 出版商
Gilmour J, Assi S, Jaegle U, Kulu D, van de Werken H, Clarke D, et al. A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification. Development. 2014;141:2391-401 pubmed 出版商
Li H, Yue R, Wei B, Gao G, Du J, Pei G. Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. EMBO J. 2014;33:1383-96 pubmed 出版商
Corken A, Russell S, Dent J, Post S, Ware J. Platelet glycoprotein Ib-IX as a regulator of systemic inflammation. Arterioscler Thromb Vasc Biol. 2014;34:996-1001 pubmed 出版商
Grinenko T, Arndt K, Portz M, Mende N, Günther M, Cosgun K, et al. Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells. J Exp Med. 2014;211:209-15 pubmed 出版商
Liu L, Wen Q, Gong R, Gilles L, Stankiewicz M, Guo M, et al. PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYN. Cell Death Dis. 2014;5:e988 pubmed 出版商
Yamane T, Washino A, Yamazaki H. Common developmental pathway for primitive erythrocytes and multipotent hematopoietic progenitors in early mouse development. Stem Cell Reports. 2013;1:590-603 pubmed 出版商
Shen B, Zhao X, O Brien K, Stojanovic Terpo A, Delaney M, Kim K, et al. A directional switch of integrin signalling and a new anti-thrombotic strategy. Nature. 2013;503:131-5 pubmed 出版商
Yamamoto K, Tsuzuki S, Minami Y, Yamamoto Y, Abe A, Ohshima K, et al. Functionally deregulated AML1/RUNX1 cooperates with BCR-ABL to induce a blastic phase-like phenotype of chronic myelogenous leukemia in mice. PLoS ONE. 2013;8:e74864 pubmed 出版商
Zhang H, Nieves J, Fraser S, Isern J, Douvaras P, Papatsenko D, et al. Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells. 2014;32:191-203 pubmed 出版商
Faraday N, Schunke K, Saleem S, Fu J, Wang B, Zhang J, et al. Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils. PLoS ONE. 2013;8:e71447 pubmed 出版商
Luo B, Tseng C, Adams G, Lee A. Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells. Stem Cells Dev. 2013;22:3062-73 pubmed 出版商
Pilat S, Carotta S, Klump H. Development of hematopoietic stem and progenitor cells from mouse embryonic stem cells, in vitro, supported by ectopic human HOXB4 expression. Methods Mol Biol. 2013;1029:129-47 pubmed 出版商
Hamanaka S, Ooehara J, Morita Y, Ema H, Takahashi S, Miyawaki A, et al. Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method. Biochem Biophys Res Commun. 2013;435:586-91 pubmed 出版商
Zeng L, An L, Fang T, Pan B, Sun H, Chen C, et al. A murine model of hepatic veno-occlusive disease induced by allogeneic hematopoietic stem cell transplantation. Cell Biochem Biophys. 2013;67:939-48 pubmed 出版商
Sato T, Ikeda M, Yotsumoto S, Shimada Y, Higuchi T, Kobayashi H, et al. Novel interferon-based pre-transplantation conditioning in the treatment of a congenital metabolic disorder. Blood. 2013;121:3267-73 pubmed 出版商
Hasan Z, Rahman M, Palani K, Syk I, Jeppsson B, Thorlacius H. Geranylgeranyl transferase regulates CXC chemokine formation in alveolar macrophages and neutrophil recruitment in septic lung injury. Am J Physiol Lung Cell Mol Physiol. 2013;304:L221-9 pubmed 出版商
Toyama H, Arai F, Hosokawa K, Ikushima Y, Suda T. N-cadherin+ HSCs in fetal liver exhibit higher long-term bone marrow reconstitution activity than N-cadherin- HSCs. Biochem Biophys Res Commun. 2012;428:354-9 pubmed 出版商
Lindqvist L, Vikstrom I, Chambers J, McArthur K, Ann Anderson M, Henley K, et al. Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor. Cell Death Dis. 2012;3:e409 pubmed 出版商
Johnson K, Hsu A, Ryu M, Wang J, Gao X, Boyer M, et al. Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity. J Clin Invest. 2012;122:3692-704 pubmed 出版商
Barbier V, Winkler I, Levesque J. Mobilization of hematopoietic stem cells by depleting bone marrow macrophages. Methods Mol Biol. 2012;904:117-38 pubmed 出版商
Tashiro K, Omori M, Kawabata K, Hirata N, Yamaguchi T, Sakurai F, et al. Inhibition of Lnk in mouse induced pluripotent stem cells promotes hematopoietic cell generation. Stem Cells Dev. 2012;21:3381-90 pubmed 出版商
Gasparetto M, Sekulovic S, Zakaryan A, Imren S, Kent D, Humphries R, et al. Varying levels of aldehyde dehydrogenase activity in adult murine marrow hematopoietic stem cells are associated with engraftment and cell cycle status. Exp Hematol. 2012;40:857-66.e5 pubmed 出版商
Lancrin C, Mazan M, Stefanska M, Patel R, Lichtinger M, Costa G, et al. GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment. Blood. 2012;120:314-22 pubmed 出版商
Koyano Nakagawa N, Kweon J, Iacovino M, Shi X, Rasmussen T, Borges L, et al. Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression. Stem Cells. 2012;30:1611-23 pubmed 出版商
Du J, Wang J, Kong G, Jiang J, Zhang J, Liu Y, et al. Signaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells. Stem Cells. 2012;30:1447-54 pubmed 出版商
Tanaka Y, Joshi A, Wilson N, Kinston S, Nishikawa S, Göttgens B. The transcriptional programme controlled by Runx1 during early embryonic blood development. Dev Biol. 2012;366:404-19 pubmed 出版商
Xiao J, Zhang C, Zhang Y, Zhang X, Zhao J, Liang J, et al. Transplantation of adipose-derived mesenchymal stem cells into a murine model of passive chronic immune thrombocytopenia. Transfusion. 2012;52:2551-8 pubmed 出版商
Barbier V, Winkler I, Wadley R, Levesque J. Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivo. Methods Mol Biol. 2012;844:45-63 pubmed 出版商
Barbier V, Nowlan B, Levesque J, Winkler I. Flow cytometry analysis of cell cycling and proliferation in mouse hematopoietic stem and progenitor cells. Methods Mol Biol. 2012;844:31-43 pubmed 出版商
Yuan H, Wang Z, Li L, Zhang H, Modi H, Horne D, et al. Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis. Blood. 2012;119:1904-14 pubmed 出版商
Rasmussen T, Kweon J, Diekmann M, Belema Bedada F, Song Q, Bowlin K, et al. ER71 directs mesodermal fate decisions during embryogenesis. Development. 2011;138:4801-12 pubmed 出版商
Joo H, Kim H, Park S, Cho H, Kim H, Lim D, et al. Angiopoietin-1 promotes endothelial differentiation from embryonic stem cells and induced pluripotent stem cells. Blood. 2011;118:2094-104 pubmed 出版商
Sprague L, Muccioli M, Pate M, Meles E, McGinty J, Nandigam H, et al. The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells. BMC Immunol. 2011;12:35 pubmed 出版商
Ding X, Lin Q, Ensenat Waser R, Rose John S, Zenke M. Polycomb group protein Bmi1 promotes hematopoietic cell development from embryonic stem cells. Stem Cells Dev. 2012;21:121-32 pubmed 出版商
Weishaupt H, Attema J. A Method to Study the Epigenetic Chromatin States of Rare Hematopoietic Stem and Progenitor Cells; MiniChIP-Chip. Biol Proced Online. 2010;12:1-17 pubmed 出版商
Taoudi S, Bee T, Hilton A, Knezevic K, Scott J, Willson T, et al. ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification. Genes Dev. 2011;25:251-62 pubmed 出版商
Jung Y, Shiozawa Y, Wang J, Patel L, Havens A, Song J, et al. Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche. Exp Hematol. 2011;39:151-166.e1 pubmed 出版商
Yokomizo T, Dzierzak E. Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development. 2010;137:3651-61 pubmed 出版商
Tzeng Y, Li H, Kang Y, Chen W, Cheng W, Lai D. Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression. Blood. 2011;117:429-39 pubmed 出版商
Paz H, Lynch M, Bogue C, Gasson J. The homeobox gene Hhex regulates the earliest stages of definitive hematopoiesis. Blood. 2010;116:1254-62 pubmed 出版商
Böiers C, Buza Vidas N, Jensen C, Pronk C, Kharazi S, Wittmann L, et al. Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development. Blood. 2010;115:5061-8 pubmed 出版商
Zhang H, Fraser S, Papazoglu C, Hoatlin M, Baron M. Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells. Stem Cells. 2009;27:2884-95 pubmed 出版商
Sato T, Onai N, Yoshihara H, Arai F, Suda T, Ohteki T. Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nat Med. 2009;15:696-700 pubmed 出版商
Lancrin C, Sroczynska P, Stephenson C, Allen T, Kouskoff V, Lacaud G. The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage. Nature. 2009;457:892-5 pubmed 出版商
Levi B, Yilmaz O, Duester G, Morrison S. Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood. 2009;113:1670-80 pubmed 出版商
Hahn B, Anderson M, Le E, La Cava A. Anti-DNA Ig peptides promote Treg cell activity in systemic lupus erythematosus patients. Arthritis Rheum. 2008;58:2488-97 pubmed 出版商
Pronk C, Attema J, Rossi D, Sigvardsson M, Bryder D. Deciphering developmental stages of adult myelopoiesis. Cell Cycle. 2008;7:706-13 pubmed
Peng J, Kitchen S, West R, Sigler R, Eisenmann K, Alberts A. Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous related formin mDia1. Cancer Res. 2007;67:7565-71 pubmed
Vassen L, Okayama T, Moroy T. Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1. Blood. 2007;109:2356-64 pubmed
Dumon S, Heath V, Tomlinson M, Gottgens B, Frampton J. Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6. Exp Hematol. 2006;34:654-63 pubmed
Bertrand J, Giroux S, Golub R, Klaine M, Jalil A, Boucontet L, et al. Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin. Proc Natl Acad Sci U S A. 2005;102:134-9 pubmed
Mitjavila Garcia M, Cailleret M, Godin I, Nogueira M, Cohen Solal K, Schiavon V, et al. Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells. Development. 2002;129:2003-13 pubmed
Teeling J, Jansen Hendriks T, Kuijpers T, de Haas M, van de Winkel J, Hack C, et al. Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia. Blood. 2001;98:1095-9 pubmed
Nieswandt B, Echtenacher B, Wachs F, Schroder J, Gessner J, Schmidt R, et al. Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice. Blood. 1999;94:684-93 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), PerCP-eFluor™ 710, eBioscience
目录# :
46-0411-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test
物种 :
小鼠
克隆 :
eBioMWReg30(MWReg30)
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test
别名 :
AI172977; alpha IIb; alphaIIb; alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; form 1; form 2; GP IIb; GP2B; GPalpha IIb; GPIIb; GT; GTA; HPA3; integrin alpha 2b; integrin alpha 2b (Cd41b); integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; integrin subunit alpha 2b; integrin subunit alpha IIb; integrin, alpha 2B; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb; platelet glycoprotein IIb of IIb/II Ia complex; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国