产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Gata-3 Monoclonal Antibody (TWAJ), PerCP-eFluor™ 710, eBioscience
目录 :
46-9966-41
规格 :
25试验
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
Percp/efluor 710
克隆名称 :
TWAJ
反应物种 :
人类, 小鼠, pigs , 猕猴
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 57
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠
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  • 流式细胞仪; 人类; 图 s3c
  • 流式细胞仪; 小鼠; 图 4c
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Deng Y, Yang Y, Wang S, Li F, Liu M, Hua Q, et al. Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3. PLoS ONE. 2015;10:e0139322 pubmed 出版商
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Li L, Yang C, Zhao Z, Xu B, Zheng M, Zhang C, et al. Skewed T-helper (Th)1/2- and Th17/T regulatory‑cell balances in patients with renal cell carcinoma. Mol Med Rep. 2015;11:947-53 pubmed 出版商
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Commandeur S, Coppola M, Dijkman K, Friggen A, van Meijgaarden K, van den Eeden S, et al. Clonal analysis of the T-cell response to in vivo expressed Mycobacterium tuberculosis protein Rv2034, using a CD154 expression based T-cell cloning method. PLoS ONE. 2014;9:e99203 pubmed 出版商
Lin C, Bradstreet T, Schwarzkopf E, Sim J, Carrero J, Chou C, et al. Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation. Nat Commun. 2014;5:3551 pubmed 出版商
Uchiyama M, Jin X, Matsuda H, Bashuda H, Imazuru T, Shimokawa T, et al. An agonistic anti-BTLA mAb (3C10) induced generation of IL-10-dependent regulatory CD4+ T cells and prolongation of murine cardiac allograft. Transplantation. 2014;97:301-9 pubmed 出版商
Villegas Mendez A, Gwyer Findlay E, de Souza J, Grady L, Saris C, Lane T, et al. WSX-1 signalling inhibits CD4? T cell migration to the liver during malaria infection by repressing chemokine-independent pathways. PLoS ONE. 2013;8:e78486 pubmed 出版商
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KEMP K, Lin Z, Zhao F, Gao B, Song J, Zhang K, et al. The serine-threonine kinase inositol-requiring enzyme 1? (IRE1?) promotes IL-4 production in T helper cells. J Biol Chem. 2013;288:33272-82 pubmed 出版商
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Blom L, Poulsen L. In vitro Th1 and Th2 cell polarization is severely influenced by the initial ratio of naïve and memory CD4+ T cells. J Immunol Methods. 2013;397:55-60 pubmed 出版商
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Gwyer Findlay E, Villegas Mendez A, de Souza J, Inkson C, Shaw T, Saris C, et al. IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection. J Immunol. 2013;190:4553-61 pubmed 出版商
Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker R, et al. Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature. 2013;496:518-22 pubmed 出版商
Peters J, Tjabringa G, Fasse E, de Oliveira V, Schalkwijk J, Koenen H, et al. Co-culture of healthy human keratinocytes and T-cells promotes keratinocyte chemokine production and ROR?t-positive IL-17 producing T-cell populations. J Dermatol Sci. 2013;69:44-53 pubmed 出版商
Chen J, Huang P, Lee C, Chen P, Chen H. A bovine whey protein extract can induce the generation of regulatory T cells and shows potential to alleviate asthma symptoms in a murine asthma model. Br J Nutr. 2013;109:1813-20 pubmed 出版商
Sawant D, Sehra S, Nguyen E, Jadhav R, Englert K, Shinnakasu R, et al. Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. J Immunol. 2012;189:4759-69 pubmed 出版商
Blom L, Poulsen L. IL-1 family members IL-18 and IL-33 upregulate the inflammatory potential of differentiated human Th1 and Th2 cultures. J Immunol. 2012;189:4331-7 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
Gata-3 Monoclonal Antibody (TWAJ), PerCP-eFluor™ 710, eBioscience
目录# :
46-9966-41
规格 :
25试验
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
人类, 小鼠, 猪, 猕猴
应用 :
Flow Cytometry: 5 µL (0.06 µg)/test
物种 :
人类, 小鼠, 猪, 猕猴
克隆 :
TWAJ
抗体亚型 :
IgG2b, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.06 µg)/test
别名 :
EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国