产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD11b Monoclonal Antibody (M1/70), eFluor™ 450, eBioscience
目录 :
48-0112-82
规格 :
100微克
价格 :
美国257
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
eFluor 450
克隆名称 :
M1/70
反应物种 :
小鼠
应用 :
免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 288
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 s3
Piliponsky A, Sharma K, Quach P, Brokaw A, Nguyen S, Orvis A, et al. Mast cell-derived factor XIIIA contributes to sexual dimorphic defense against group B streptococcal infections. J Clin Invest. 2022;132: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Melese E, Franks E, Cederberg R, Harbourne B, Shi R, Wadsworth B, et al. CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development. Oncoimmunology. 2022;11:2010905 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2j
van Vloten J, Matuszewska K, Minow M, Minott J, Santry L, Pereira M, et al. Oncolytic Orf virus licenses NK cells via cDC1 to activate innate and adaptive antitumor mechanisms and extends survival in a murine model of late-stage ovarian cancer. J Immunother Cancer. 2022;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6b
Droho S, Cuda C, Perlman H, Lavine J. Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis. Sci Rep. 2021;11:18084 pubmed 出版商
  • 流式细胞仪; 小鼠
Karki R, Sharma B, Tuladhar S, Williams E, Zalduondo L, Samir P, et al. Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes. Cell. 2021;184:149-168.e17 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Hurrell B, Galle Treger L, Jahani P, Howard E, Helou D, Banie H, et al. TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity. Cell Rep. 2019;29:4509-4524.e5 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 ex3d
Samir P, Kesavardhana S, Patmore D, Gingras S, Malireddi R, Karki R, et al. DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome. Nature. 2019;573:590-594 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Chopin M, Lun A, Zhan Y, Schreuder J, Coughlan H, D Amico A, et al. Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT. Immunity. 2019;50:77-90.e5 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Wheeler D, Sariol A, Meyerholz D, Perlman S. Microglia are required for protection against lethal coronavirus encephalitis in mice. J Clin Invest. 2018;128:931-943 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3g
Linehan J, Harrison O, Han S, Byrd A, Vujkovic Cvijin I, Villarino A, et al. Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair. Cell. 2018;172:784-796.e18 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s5a
Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172:517-533.e20 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 s13
Schneider C, Oellerich T, Baldauf H, Schwarz S, Thomas D, Flick R, et al. SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia. Nat Med. 2017;23:250-255 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:300; 图 s3c
Karki R, Man S, Malireddi R, Kesavardhana S, Zhu Q, Burton A, et al. NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer. Nature. 2016;540:583-587 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 表 1
  • 免疫细胞化学; 小鼠; 1:200; 表 1
Jackson Jones L, Duncan S, Magalhaes M, Campbell S, Maizels R, McSorley H, et al. Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nat Commun. 2016;7:12651 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Agarwal S, Drake J, Qureshi A, Loder S, Li S, Shigemori K, et al. Characterization of Cells Isolated from Genetic and Trauma-Induced Heterotopic Ossification. PLoS ONE. 2016;11:e0156253 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Al Sadoun H, Burgess M, Hentges K, Mace K. Enforced Expression of Hoxa3 Inhibits Classical and Promotes Alternative Activation of Macrophages In Vitro and In Vivo. J Immunol. 2016;197:872-84 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 st2
Albarrán Juárez J, Kaur H, Grimm M, Offermanns S, Wettschureck N. Lineage tracing of cells involved in atherosclerosis. Atherosclerosis. 2016;251:445-453 pubmed 出版商
  • 流式细胞仪; 小鼠
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Nadaud S, Flamant M, Le Goff W, Balse E, Pavoine C. Transcriptomic and Lipidomic Mapping of Macrophages in the Hub of Chronic Beta-Adrenergic-Stimulation Unravels Hypertrophy-, Proliferation-, and Lipid Metabolism-Related Genes as Novel Potential Markers of Early Hypertrophy or Heart Failure. Biomedicines. 2022;10: pubmed 出版商
Hester A, Semwal M, Cepeda S, Xiao Y, Rueda M, Wimberly K, et al. Redox regulation of age-associated defects in generation and maintenance of T cell self-tolerance and immunity to foreign antigens. Cell Rep. 2022;38:110363 pubmed 出版商
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Zhang H, Cheng N, Li Z, Bai L, Fang C, Li Y, et al. DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia. Cancer Commun (Lond). 2021;41:1116-1136 pubmed 出版商
Flamant M, Mougenot N, Balse E, Le Fevre L, Atassi F, Gautier E, et al. Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure. Sci Rep. 2021;11:17982 pubmed 出版商
Mittal A, Wang M, Vidyarthi A, Yanez D, Pizzurro G, Thakral D, et al. Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma. Sci Rep. 2021;11:10731 pubmed 出版商
Amobi McCloud A, Muthuswamy R, Battaglia S, Yu H, Liu T, Wang J, et al. IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation. Front Immunol. 2021;12:678999 pubmed 出版商
Bieniasz Krzywiec P, Martín Pérez R, Riera Domingo C, Mazzone M. Isolation and separation of murine tumor-associated macrophages (TAMs) subpopulations from orthotopic 4T1 breast tumors. STAR Protoc. 2021;2:100481 pubmed 出版商
Chou H, Grant M, Bolt A, Guilbert C, Plourde D, Mwale F, et al. Tungsten Increases Sex-Specific Osteoclast Differentiation in Murine Bone. Toxicol Sci. 2021;179:135-146 pubmed 出版商
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Fu W, Li H, Fu H, Zhao S, Shi W, Sun M, et al. The SIRT3 and SIRT6 Promote Prostate Cancer Progression by Inhibiting Necroptosis-Mediated Innate Immune Response. J Immunol Res. 2020;2020:8820355 pubmed 出版商
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McElroy G, Reczek C, Reyfman P, Mithal D, Horbinski C, Chandel N. NAD+ Regeneration Rescues Lifespan, but Not Ataxia, in a Mouse Model of Brain Mitochondrial Complex I Dysfunction. Cell Metab. 2020;32:301-308.e6 pubmed 出版商
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Miao W, Zhao Y, Huang Y, Chen D, Luo C, Su W, et al. IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury. J Immunol. 2020;204:1486-1498 pubmed 出版商
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Gannavaram S, Bhattacharya P, Siddiqui A, Ismail N, Madhavan S, Nakhasi H. miR-21 Expression Determines the Early Vaccine Immunity Induced by LdCen-/- Immunization. Front Immunol. 2019;10:2273 pubmed 出版商
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Wakley A, Leeming R, Malon J, Arabatzis T, Yuen Koh W, Cao L. Contribution of CD137L to Sensory Hypersensitivity in a Murine Model of Neuropathic Pain. Eneuro. 2018;5: pubmed 出版商
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Liu R, King A, Bouillet P, Tarlinton D, Strasser A, Heierhorst J. Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner. Front Immunol. 2018;9:592 pubmed 出版商
Li X, Gadzinsky A, Gong L, Tong H, Calderon V, Li Y, et al. Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction. Immunity. 2018;48:530-541.e6 pubmed 出版商
Lim D, Kim W, Lee C, Bae H, Kim J. Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung. Front Physiol. 2018;9:47 pubmed 出版商
Barnette D, Cahill T, Gunadasa Rohling M, Carr C, Freeman M, Riley P. iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction. JCI Insight. 2018;3: pubmed 出版商
Guo X, Chu L, Ke F, Mu L, Li Z, Cai J, et al. Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells. Oncotarget. 2017;8:108981-108988 pubmed 出版商
Linde N, Casanova Acebes M, Sosa M, Mortha A, Rahman A, Farias E, et al. Macrophages orchestrate breast cancer early dissemination and metastasis. Nat Commun. 2018;9:21 pubmed 出版商
Weng H, Huang H, Wu H, Qin X, Zhao B, Dong L, et al. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018;22:191-205.e9 pubmed 出版商
Stephen J, Scales H, Benson R, Erben D, Garside P, Brewer J. Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity. NPJ Vaccines. 2017;2:1 pubmed 出版商
Wang Y, Xiao M, Tao C, Chen J, Wang Z, Yang J, et al. Inactivation of mTORC1 Signaling in Osterix-expressing Cells Impairs B-cell Differentiation. J Bone Miner Res. 2017;: pubmed 出版商
Turaj A, Hussain K, Cox K, Rose Zerilli M, Testa J, Dahal L, et al. Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment. Cancer Cell. 2017;32:777-791.e6 pubmed 出版商
Wang X, Zhang Y, Wang Z, Liu X, Zhu G, Han G, et al. Anti?IL?39 (IL?23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus?like mice. Mol Med Rep. 2017;: pubmed 出版商
Zhu D, Tan J, Maleken A, Muljadi R, Chan S, Lau S, et al. Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury. Stem Cell Res Ther. 2017;8:257 pubmed 出版商
Briere D, Sudhakar N, Woods D, Hallin J, Engstrom L, Aranda R, et al. The class I/IV HDAC inhibitor mocetinostat increases tumor antigen presentation, decreases immune suppressive cell types and augments checkpoint inhibitor therapy. Cancer Immunol Immunother. 2018;67:381-392 pubmed 出版商
Zhang B, Zhang J, Shi H, Mao F, Wang J, Yan Y, et al. A novel method to isolate mesenchymal stem cells from mouse umbilical cord. Mol Med Rep. 2017;: pubmed 出版商
Zamanian Daryoush M, Lindner D, DiDonato J, Wagner M, Buffa J, Rayman P, et al. Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer. Oncotarget. 2017;8:71965-71980 pubmed 出版商
Kastenschmidt J, Avetyan I, Villalta S. Characterization of the Inflammatory Response in Dystrophic Muscle Using Flow Cytometry. Methods Mol Biol. 2018;1687:43-56 pubmed 出版商
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Qin Y, Wu L, Ouyang Y, Zhou P, Zhou H, Wang Y, et al. MiR-125a Is a critical modulator for neutrophil development. PLoS Genet. 2017;13:e1007027 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD11b Monoclonal Antibody (M1/70), eFluor™ 450, eBioscience
目录# :
48-0112-82
规格 :
100微克
价格 :
美国257
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.125 µg/test
物种 :
小鼠
克隆 :
M1/70
抗体亚型 :
IgG2b, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.125 µg/test
别名 :
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国