产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
SOX2多克隆抗体
目录 :
48-1400
规格 :
100微克
价格 :
美国375.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 8
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:125; 图 4s1b
Battaglia R, Beltran A, Delic S, Dumitru R, Robinson J, Kabiraj P, et al. Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander disease severity. elife. 2019;8: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 e2a, e2d
  • 免疫印迹; 小鼠; 1:250; 图 e1c
Strebinger D, Deluz C, Friman E, Govindan S, Alber A, Suter D. Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions. Mol Syst Biol. 2019;15:e9002 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 1h
Deluz C, Friman E, Strebinger D, Benke A, Raccaud M, Callegari A, et al. A role for mitotic bookmarking of SOX2 in pluripotency and differentiation. Genes Dev. 2016;30:2538-2550 pubmed
  • 免疫细胞化学; 大鼠; 1:100; 图 5
Cui Y, Han J, Xiao Z, Chen T, Wang B, Chen B, et al. The miR-20-Rest-Wnt signaling axis regulates neural progenitor cell differentiation. Sci Rep. 2016;6:23300 pubmed 出版商
Munro M, Peng L, Wickremesekera S, Tan S. Colon adenocarcinoma-derived cells that express induced-pluripotent stem cell markers possess stem cell function. PLoS ONE. 2020;15:e0232934 pubmed 出版商
Friman E, Deluz C, Meireles Filho A, Govindan S, Gardeux V, Deplancke B, et al. Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle. elife. 2019;8: pubmed 出版商
Donato V, Bonora M, Simoneschi D, Sartini D, Kudo Y, Saraf A, et al. The TDH-GCN5L1-Fbxo15-KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells. Nat Cell Biol. 2017;19:341-351 pubmed 出版商
Míguez D. A Branching Process to Characterize the Dynamics of Stem Cell Differentiation. Sci Rep. 2015;5:13265 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
SOX2多克隆抗体
目录# :
48-1400
规格 :
100微克
价格 :
美国375.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 2-3 µg/mL, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 5 µg, Western Blot: 1-3 µg/mL
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
免疫原 :
Synthetic peptide derived from the N-terminal region of the human SOX2 protein
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 2-3 µg/mL, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 5 µg, Western Blot: 1-3 µg/mL
别名 :
ANOP3; cb236; lcc; MCOPS3; RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y)-box 2; SRY box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国