产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Ki-67 Monoclonal Antibody (SolA15), eFluor 450, eBioscience™
目录 :
48-5698-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
eFluor 450
克隆名称 :
SolA15
反应物种 :
食蟹猴, 人类, 小鼠, 大鼠,
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 73
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 s1a
Gerriets V, Kishton R, Johnson M, Cohen S, Siska P, Nichols A, et al. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. Nat Immunol. 2016;17:1459-1466 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s8
Traka M, Podojil J, McCarthy D, Miller S, Popko B. Oligodendrocyte death results in immune-mediated CNS demyelination. Nat Neurosci. 2016;19:65-74 pubmed 出版商
Díaz Salazar C, Sun J. Coordinated Viral Control by Cytotoxic Lymphocytes Ensures Optimal Adaptive NK Cell Responses. Cell Rep. 2020;32:108186 pubmed 出版商
Choi H, Deng J, Li S, Silk T, Dong L, Brea E, et al. Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer. Cell Rep. 2019;27:806-819.e5 pubmed 出版商
Glal D, Sudhakar J, Lu H, Liu M, Chiang H, Liu Y, et al. ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases. Front Immunol. 2018;9:2522 pubmed 出版商
Koren E, Yosefzon Y, Ankawa R, Soteriou D, Jacob A, Nevelsky A, et al. ARTS mediates apoptosis and regeneration of the intestinal stem cell niche. Nat Commun. 2018;9:4582 pubmed 出版商
Stratton J, Assinck P, Sinha S, Kumar R, Moulson A, Patrick N, et al. Factors Within the Endoneurial Microenvironment Act to Suppress Tumorigenesis of MPNST. Front Cell Neurosci. 2018;12:356 pubmed 出版商
Kiang L, Ross B, Yao J, Shanmugam S, Andrews C, Hansen S, et al. Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment. Invest Ophthalmol Vis Sci. 2018;59:3767-3778 pubmed 出版商
Dergilev K, Tsokolaeva Z, Makarevich P, Beloglazova I, Zubkova E, Boldyreva M, et al. C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats. Biomed Res Int. 2018;2018:3536854 pubmed 出版商
Jurisevic M, Arsenijević A, Pantic J, Gajovic N, Milovanovic J, Milovanovic M, et al. The organic ester O,O'-diethyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis. Oncotarget. 2018;9:28195-28212 pubmed 出版商
Xu C, Gao X, Wei Q, Nakahara F, Zimmerman S, Mar J, et al. Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow. Nat Commun. 2018;9:2449 pubmed 出版商
Moll S, Yasui Y, Abed A, Murata T, Shimada H, Maeda A, et al. Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime. J Transl Med. 2018;16:148 pubmed 出版商
Maryanovich M, Zahalka A, Pierce H, Pinho S, Nakahara F, Asada N, et al. Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. Nat Med. 2018;24:782-791 pubmed 出版商
Lopes N, Charaix J, Cedile O, Serge A, Irla M. Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells. Nat Commun. 2018;9:1262 pubmed 出版商
Arce Vargas F, Furness A, Litchfield K, Joshi K, Rosenthal R, Ghorani E, et al. Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies. Cancer Cell. 2018;33:649-663.e4 pubmed 出版商
Mitroulis I, Ruppova K, Wang B, Chen L, Grzybek M, Grinenko T, et al. Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell. 2018;172:147-161.e12 pubmed 出版商
Nguyen Thanh T, Kim D, Lee S, Kim W, Park S, Kang K. Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice. Int J Mol Med. 2018;41:95-106 pubmed 出版商
Carrero J, McCarthy D, Ferris S, Wan X, Hu H, Zinselmeyer B, et al. Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice. Proc Natl Acad Sci U S A. 2017;114:E10418-E10427 pubmed 出版商
Epshtein A, Rachi E, Sakhneny L, Mizrachi S, Baer D, Landsman L. Neonatal pancreatic pericytes support β-cell proliferation. Mol Metab. 2017;6:1330-1338 pubmed 出版商
Chu F, Hu Y, Zhou Y, Guo M, Lu J, Zheng W, et al. MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway. Clin Exp Immunol. 2017;: pubmed 出版商
Mass E, Jacome Galarza C, Blank T, Lazarov T, Durham B, Ozkaya N, et al. A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease. Nature. 2017;549:389-393 pubmed 出版商
Donovan P, Dubey O, Kallioinen S, Rogers K, Muehlethaler K, Muller P, et al. Paracrine Activin-A Signaling Promotes Melanoma Growth and Metastasis through Immune Evasion. J Invest Dermatol. 2017;137:2578-2587 pubmed 出版商
Wang S, Xia P, Chen Y, Qu Y, Xiong Z, Ye B, et al. Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation. Cell. 2017;171:201-216.e18 pubmed 出版商
Shintani Y, Ito T, Fields L, Shiraishi M, Ichihara Y, Sato N, et al. IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice. Sci Rep. 2017;7:6877 pubmed 出版商
Zang S, Li J, Yang H, Zeng H, Han W, Zhang J, et al. Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis. J Clin Invest. 2017;127:2998-3012 pubmed 出版商
Contrepois K, Coudereau C, Benayoun B, Schuler N, Roux P, Bischof O, et al. Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression. Nat Commun. 2017;8:14995 pubmed 出版商
Miao T, Symonds A, Singh R, Symonds J, Ogbe A, Omodho B, et al. Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017;214:1787-1808 pubmed 出版商
Dai K, Huang L, Huang Y, Chen Z, Yang L, Jiang Y. 1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8+ T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model. Front Immunol. 2017;8:320 pubmed 出版商
Hérault A, Binnewies M, Leong S, Calero Nieto F, Zhang S, Kang Y, et al. Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis. Nature. 2017;544:53-58 pubmed 出版商
Asada N, Kunisaki Y, Pierce H, Wang Z, Fernandez N, Birbrair A, et al. Differential cytokine contributions of perivascular haematopoietic stem cell niches. Nat Cell Biol. 2017;19:214-223 pubmed 出版商
Sonner J, Deumelandt K, Ott M, Thomé C, Rauschenbach K, Schulz S, et al. The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas. Oncoimmunology. 2016;5:e1240858 pubmed 出版商
Chen L, Yi X, Goswami S, Ahn Y, Roybal J, Yang Y, et al. Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression. Oncoimmunology. 2016;5:e1234570 pubmed 出版商
Andriani G, Almeida V, Faggioli F, Mauro M, Tsai W, Santambrogio L, et al. Whole Chromosome Instability induces senescence and promotes SASP. Sci Rep. 2016;6:35218 pubmed 出版商
Chudnovskiy A, Mortha A, Kana V, Kennard A, Ramírez J, Rahman A, et al. Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. Cell. 2016;167:444-456.e14 pubmed 出版商
Sato Y, Mii A, Hamazaki Y, Fujita H, Nakata H, Masuda K, et al. Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney. JCI Insight. 2016;1:e87680 pubmed 出版商
Liang J, Zhang Y, Xie T, Liu N, Chen H, Geng Y, et al. Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice. Nat Med. 2016;22:1285-1293 pubmed 出版商
Sun T, Rojas O, Li C, Ward L, Philpott D, Gommerman J. Intestinal Batf3-dependent dendritic cells are required for optimal antiviral T-cell responses in adult and neonatal mice. Mucosal Immunol. 2017;10:775-788 pubmed 出版商
Zhu X, Li K, Guo X, Wang J, Xiang Y. Schwann cell proliferation and differentiation that is induced by ferulic acid through MEK1/ERK1/2 signalling promotes peripheral nerve remyelination following crush injury in rats. Exp Ther Med. 2016;12:1915-1921 pubmed
Ramo K, Sugamura K, Craige S, Keaney J, Davis R. Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. elife. 2016;5: pubmed 出版商
Büchel G, Schulte J, Harrison L, Batzke K, Schüller U, Hansen W, et al. Immune response modulation by Galectin-1 in a transgenic model of neuroblastoma. Oncoimmunology. 2016;5:e1131378 pubmed 出版商
Eminaga S, Teekakirikul P, Seidman C, Seidman J. Detection of Cell Proliferation Markers by Immunofluorescence Staining and Microscopy Imaging in Paraffin-Embedded Tissue Sections. Curr Protoc Mol Biol. 2016;115:14.25.1-14.25.14 pubmed 出版商
Ersching J, Basso A, Kalich V, Bortoluci K, Rodrigues M. A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells. PLoS Pathog. 2016;12:e1005698 pubmed 出版商
Fox R, Lytle N, Jaquish D, Park F, Ito T, Bajaj J, et al. Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature. 2016;534:407-411 pubmed 出版商
Sigl V, Owusu Boaitey K, Joshi P, Kavirayani A, Wirnsberger G, Novatchkova M, et al. RANKL/RANK control Brca1 mutation- . Cell Res. 2016;26:761-74 pubmed 出版商
Holmgaard R, Zamarin D, Lesokhin A, Merghoub T, Wolchok J. Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressing tumors. EBioMedicine. 2016;6:50-58 pubmed 出版商
Tian Y, Kuo C, Akbari O, Ou J. Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission. Immunity. 2016;44:1204-14 pubmed 出版商
Sobecki M, Mrouj K, Camasses A, Parisis N, Nicolas E, Llères D, et al. The cell proliferation antigen Ki-67 organises heterochromatin. elife. 2016;5:e13722 pubmed 出版商
Soucie E, Weng Z, Geirsdóttir L, Molawi K, Maurizio J, Fenouil R, et al. Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells. Science. 2016;351:aad5510 pubmed 出版商
Barazzuol L, Rickett N, Ju L, Jeggo P. Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells. J Cell Sci. 2015;128:3597-606 pubmed 出版商
Chang C, Zhang M, Rajapakshe K, Coarfa C, Edwards D, Huang S, et al. Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage. Stem Cell Reports. 2015;5:378-91 pubmed 出版商
Lovisa S, LeBleu V, Tampe B, Sugimoto H, Vadnagara K, Carstens J, et al. Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis. Nat Med. 2015;21:998-1009 pubmed 出版商
Yan S, Xu Z, Lou F, Zhang L, Ke F, Bai J, et al. NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis. Nat Commun. 2015;6:7652 pubmed 出版商
Richter R, Rüster B, Bistrian R, Forssmann W, Seifried E, Henschler R. Beta-Chemokine CCL15 Affects the Adhesion and Migration of Hematopoietic Progenitor Cells. Transfus Med Hemother. 2015;42:29-37 pubmed 出版商
Giera S, Deng Y, Luo R, Ackerman S, Mogha A, Monk K, et al. The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development. Nat Commun. 2015;6:6121 pubmed 出版商
Puleston D, Zhang H, Powell T, Lipina E, Sims S, Panse I, et al. Autophagy is a critical regulator of memory CD8(+) T cell formation. elife. 2014;3: pubmed 出版商
Chen L, Gibbons D, Goswami S, Cortez M, Ahn Y, Byers L, et al. Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression. Nat Commun. 2014;5:5241 pubmed 出版商
Little M, Hurst R, Else K. Dynamic changes in macrophage activation and proliferation during the development and resolution of intestinal inflammation. J Immunol. 2014;193:4684-95 pubmed 出版商
Desai T, Brownfield D, Krasnow M. Alveolar progenitor and stem cells in lung development, renewal and cancer. Nature. 2014;507:190-4 pubmed 出版商
D Cruz L, Stradner M, Yang C, Goldrath A. E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation. J Immunol. 2014;192:2227-36 pubmed 出版商
Joedicke J, Dietze K, Zelinskyy G, Dittmer U. The phenotype and activation status of regulatory T cells during Friend retrovirus infection. Virol Sin. 2014;29:48-60 pubmed 出版商
Murakami S, Yamamoto M, Motohashi H. Hematopoietic stem and progenitor cell activation during chronic dermatitis provoked by constitutively active aryl-hydrocarbon receptor driven by Keratin 14 promoter. Toxicol Sci. 2014;138:47-58 pubmed 出版商
Vom Berg J, Vrohlings M, Haller S, Haimovici A, Kulig P, Sledzińska A, et al. Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection. J Exp Med. 2013;210:2803-11 pubmed 出版商
Villegas Mendez A, Gwyer Findlay E, de Souza J, Grady L, Saris C, Lane T, et al. WSX-1 signalling inhibits CD4? T cell migration to the liver during malaria infection by repressing chemokine-independent pathways. PLoS ONE. 2013;8:e78486 pubmed 出版商
Tata P, Mou H, Pardo Saganta A, Zhao R, Prabhu M, Law B, et al. Dedifferentiation of committed epithelial cells into stem cells in vivo. Nature. 2013;503:218-23 pubmed 出版商
Cooney L, Gupta M, Thomas S, Mikolajczak S, Choi K, Gibson C, et al. Short-lived effector CD8 T cells induced by genetically attenuated malaria parasite vaccination express CD11c. Infect Immun. 2013;81:4171-81 pubmed 出版商
Lischke T, Heesch K, Schumacher V, Schneider M, Haag F, Koch Nolte F, et al. CD38 controls the innate immune response against Listeria monocytogenes. Infect Immun. 2013;81:4091-9 pubmed 出版商
Liu J, Copland D, Horie S, Wu W, Chen M, Xu Y, et al. Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice. PLoS ONE. 2013;8:e72935 pubmed 出版商
Povinelli B, Nemeth M. Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor. Stem Cells. 2014;32:105-15 pubmed 出版商
Yammani R, Haas K. Primate B-1 cells generate antigen-specific B cell responses to T cell-independent type 2 antigens. J Immunol. 2013;190:3100-8 pubmed 出版商
Schaefer J, Montufar Solis D, Nakra N, Vigneswaran N, Klein J. Small intestine inflammation in Roquin-mutant and Roquin-deficient mice. PLoS ONE. 2013;8:e56436 pubmed 出版商
Pang I, Ichinohe T, Iwasaki A. IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8? T cell responses to influenza A virus. Nat Immunol. 2013;14:246-53 pubmed 出版商
Yan L, Singh L, Zhang L, Xu Y. Role of OGR1 in myeloid-derived cells in prostate cancer. Oncogene. 2014;33:157-64 pubmed 出版商
Ma C, Kapanadze T, Gamrekelashvili J, Manns M, Korangy F, Greten T. Anti-Gr-1 antibody depletion fails to eliminate hepatic myeloid-derived suppressor cells in tumor-bearing mice. J Leukoc Biol. 2012;92:1199-206 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
Ki-67 Monoclonal Antibody (SolA15), eFluor 450, eBioscience™
目录# :
48-5698-80
规格 :
25微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
Canine, Cynomolgus Monkey, Human, Mouse, Non-human primate, Rat
应用 :
Flow Cytometry: 0.125 µg/test
物种 :
Canine, Cynomolgus Monkey, Human, Mouse, Non-human primate, Rat
克隆 :
SolA15
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.125 µg/test
别名 :
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国