产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PGP9.5单克隆抗体(BH7)
目录 :
480012
规格 :
100微升
价格 :
美国476
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
BH7
反应物种 :
人类, 小鼠, 大鼠, , pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠; 1:1000; 图 3
Boric M, Jelicic Kadic A, Puljak L. Cutaneous expression of calcium/calmodulin-dependent protein kinase II in rats with type 1 and type 2 diabetes. J Chem Neuroanat. 2014;61-62:140-6 pubmed 出版商
  • 免疫印迹; 人类
Zhao Z, Wu L, Xiong R, Wang L, Zhang B, Wang C, et al. MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer's disease. Neuroscience. 2014;275:232-7 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:500
Filipović N, Zuvan L, Masek T, Tokalić R, Grkovic I. Gender and gonadectomy influence on neurons in superior cervical ganglia of sexually mature rats. Neurosci Lett. 2014;563:55-60 pubmed 出版商
  • 免疫组化; 大鼠; 1:1000; 图 4
Jelicic Kadic A, Boric M, Vidak M, Ferhatovic L, Puljak L. Changes in epidermal thickness and cutaneous innervation during maturation in long-term diabetes. J Tissue Viability. 2014;23:7-12 pubmed 出版商
  • 免疫组化; 大鼠; 1:1000; 图 5
Boric M, Skopljanac I, Ferhatovic L, Jelicic Kadic A, Banozic A, Puljak L. Reduced epidermal thickness, nerve degeneration and increased pain-related behavior in rats with diabetes type 1 and 2. J Chem Neuroanat. 2013;53:33-40 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
Zhang Y, Zhou L, Rouge L, Phillips A, Lam C, Liu P, et al. Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7. Nat Chem Biol. 2013;9:51-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Lee J, Ladd A, Hagert E. Immunofluorescent triple-staining technique to identify sensory nerve endings in human thumb ligaments. Cells Tissues Organs. 2012;195:456-64 pubmed 出版商
Jurić M, Zeitler J, Vukojevic K, Bocina I, Grobe M, Kretzschmar G, et al. Expression of Connexins 37, 43 and 45 in Developing Human Spinal Cord and Ganglia. Int J Mol Sci. 2020;21: pubmed 出版商
Urlic M, Urlić I, Urlić H, Masek T, Benzon B, Vitlov Uljevic M, et al. Effects of Different n6/n3 PUFAs Dietary Ratio on Cardiac Diabetic Neuropathy. Nutrients. 2020;12: pubmed 出版商
Hewings D, Heideker J, Ma T, AhYoung A, El Oualid F, Amore A, et al. Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes. Nat Commun. 2018;9:1162 pubmed 出版商
Bheda A, Gullapalli A, Caplow M, Pagano J, Shackelford J. Ubiquitin editing enzyme UCH L1 and microtubule dynamics: implication in mitosis. Cell Cycle. 2010;9:980-94 pubmed
产品信息
产品类型 :
抗体
产品名称 :
PGP9.5单克隆抗体(BH7)
目录# :
480012
规格 :
100微升
价格 :
美国476
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
牛, 人类, 小鼠, 猪, 大鼠
应用 :
Immunocytochemistry: 1:500, Immunohistochemistry: 1:500-1:5,000, Western Blot: 1:5,000
物种 :
牛, 人类, 小鼠, 猪, 大鼠
克隆 :
BH7
抗体亚型 :
IgG1
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
PGP9.5 (Protein gene product 9.5, UCH-L1, PARK5) is a neuron specific protein, structurally and immunologically distinct from neuron specific enolase. PGP9.5 has a molecular weight of 27 kDa and was first identified by high resolution two dimensional PAGE. PGP9.5 is a member of ubiquitin carboxyl-terminal hydrolase family 1 (peptidase family C12) with a ubiquitin carboxyl-terminal hydrolase domain. PGP9.5 is well known for having ubiquitin hydrolase and ligase activities that hydrolyzes small C-terminal adducts of ubiquitin to generate ubiquitin monomers. PGP9.5 is present in neurons and nerve fibers at all levels of the central and peripheral nervous system, in neuroendocrine cells, in segments of the renal tubules, in spermatogonia and Leydig cells of the testis, in ova and in some cells of both the pregnant and non-pregnant corpus luteum. Over expression of PGP9.5 leads to non-small cell lung cancer while decreased expression leads to Huntington disease and Alzheimer disease. Since PGP9.5 is present in cellular inclusions, it can be a useful as a neuronal marker and in the studies of neurodegenerative disorders such as with Parkinson disease.
免疫原 :
重组全长人类UCHL1纯化来自大肠杆菌
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:500, Immunohistochemistry: 1:500-1:5,000, Western Blot: 1:5,000
别名 :
AW822034; C88048; epididymis luminal protein 117; epididymis secretory protein Li 53; gad; gracile axonal dystrophy; HEL-117; HEL-S-53; MGC133697 protein; NDGOA; neuron cytoplasmic protein 9.5; OTTHUMP00000218137; OTTHUMP00000218139; OTTHUMP00000218140; OTTHUMP00000218141; PARK5; PGP 9.5; PGP9.5; PGP95; protein gene product 9.5; R75593; ubiquitin carboxyl-terminal esterase; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin carboxyl-terminal hydrolase L1; ubiquitin carboxy-terminal hydrolase L1; ubiquitin C-terminal hydrolase; ubiquitin C-terminal hydrolase 1; ubiquitin C-terminal hydrolase L1; ubiquitin thioesterase L1; ubiquitin thiolesterase; ubiquitin thiolesterase L1; UCHL; UCHL1; UCH-L1; UCHL-1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国