产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Pannexin 1 Polyclonal Antibody
目录 :
487900
规格 :
100微克
价格 :
美国428
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
小鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
文章摘录数: 5
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:100; 图 2
Seref Ferlengez Z, Maung S, Schaffler M, Spray D, Suadicani S, Thi M. P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes. PLoS ONE. 2016;11:e0155107 pubmed 出版商
Nouri Nejad D, O Donnell B, Patil C, Sanchez Pupo R, Johnston D, Sayedyahossein S, et al. Pannexin 1 mutation found in melanoma tumour reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein. Mol Biol Cell. 2021;:mbcE19100585 pubmed 出版商
Seref Ferlengez Z, Urban Maldonado M, Sun H, Schaffler M, Suadicani S, Thi M. Role of pannexin 1 channels in load-induced skeletal response. Ann N Y Acad Sci. 2019;1442:79-90 pubmed 出版商
Zorzi V, Paciello F, Ziraldo G, Peres C, Mazzarda F, Nardin C, et al. Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function. Front Mol Neurosci. 2017;10:379 pubmed 出版商
Keller A, Diederich L, Panknin C, DeLalio L, Drake J, Sherman R, et al. Possible roles for ATP release from RBCs exclude the cAMP-mediated Panx1 pathway. Am J Physiol Cell Physiol. 2017;313:C593-C603 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
Pannexin 1 Polyclonal Antibody
目录# :
487900
规格 :
100微克
价格 :
美国428
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
小鼠
应用 :
Immunohistochemistry: 2-4 µg/mL, Western Blot: 1-3 µg/mL
物种 :
小鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
免疫原 :
Synthetic peptide derived from the N-terminal region of the mouse Pannexin 1 protein (Accession# NP_062355), which is identical to rat and human sequences.
格式 :
液体
应用w/稀释 :
Immunohistochemistry: 2-4 µg/mL, Western Blot: 1-3 µg/mL
别名 :
AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国