产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
LYVE1 Monoclonal Antibody (ALY7), eFluor™ 660, eBioscience
目录 :
50-0443-82
规格 :
100微克
价格 :
美国388
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
efluor 660
克隆名称 :
ALY7
反应物种 :
小鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 49
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 2e
Hayakawa M, Sakata A, Hayakawa H, Matsumoto H, Hiramoto T, Kashiwakura Y, et al. Characterization and visualization of murine coagulation factor VIII-producing cells in vivo. Sci Rep. 2021;11:14824 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 1d
Hu X, Deng Q, Ma L, Li Q, Chen Y, Liao Y, et al. Meningeal lymphatic vessels regulate brain tumor drainage and immunity. Cell Res. 2020;30:229-243 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 1h
Louveau A, Herz J, Alme M, Salvador A, Dong M, Viar K, et al. CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature. Nat Neurosci. 2018;21:1380-1391 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1a
Dá Mesquita S, Louveau A, Vaccari A, Smirnov I, Cornelison R, Kingsmore K, et al. Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease. Nature. 2018;560:185-191 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 9b
Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed 出版商
Kobayashi D, Sugiura Y, Umemoto E, Takeda A, Ueta H, Hayasaka H, et al. Extracellular ATP Limits Homeostatic T Cell Migration Within Lymph Nodes. Front Immunol. 2021;12:786595 pubmed 出版商
Zhang D, Huang J, Sun X, Chen H, Huang S, Yang J, et al. Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway. Nat Commun. 2021;12:4391 pubmed 出版商
Nishina T, Deguchi Y, Ohshima D, Takeda W, Ohtsuka M, Shichino S, et al. Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer. Nat Commun. 2021;12:2281 pubmed 出版商
Nguyen S, Ahn S, Greenberg J, Collaer B, Agnew D, Arora R, et al. Integrins mediate placental extracellular vesicle trafficking to lung and liver in vivo. Sci Rep. 2021;11:4217 pubmed 出版商
Alexander J, Seua A, Arroyo L, Ray P, Wangzhou A, Hei x3b2 L xfc ckemann L, et al. Nasal administration of mitochondria reverses chemotherapy-induced cognitive deficits. Theranostics. 2021;11:3109-3130 pubmed 出版商
Hofmann J, Gadjalova I, Mishra R, Ruland J, Keppler S. Efficient Tissue Clearing and Multi-Organ Volumetric Imaging Enable Quantitative Visualization of Sparse Immune Cell Populations During Inflammation. Front Immunol. 2020;11:599495 pubmed 出版商
Bolte A, Dutta A, Hurt M, Smirnov I, Kovacs M, McKee C, et al. Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis. Nat Commun. 2020;11:4524 pubmed 出版商
Shrestha S, Cho W, Stump B, Imani J, Lamattina A, Louis P, et al. FK506 induces lung lymphatic endothelial cell senescence and downregulates LYVE-1 expression, with associated decreased hyaluronan uptake. Mol Med. 2020;26:75 pubmed 出版商
Strunz M, Simon L, Ansari M, Kathiriya J, Angelidis I, Mayr C, et al. Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis. Nat Commun. 2020;11:3559 pubmed 出版商
Krausgruber T, Fortelny N, Fife Gernedl V, Senekowitsch M, Schuster L, Lercher A, et al. Structural cells are key regulators of organ-specific immune responses. Nature. 2020;583:296-302 pubmed 出版商
Chen J, Wang L, Xu H, Xing L, Zhuang Z, Zheng Y, et al. Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage. Nat Commun. 2020;11:3159 pubmed 出版商
Elham E, Wumaier R, Wang C, Luo X, Chen T, Zhong N. Anatomic evidence shows that lymphatic drainage exists in the pituitary to loop the cerebral lymphatic circulation. Med Hypotheses. 2020;143:109898 pubmed 出版商
Etzerodt A, Moulin M, Doktor T, Delfini M, Mossadegh Keller N, Bajenoff M, et al. Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer. J Exp Med. 2020;217: pubmed 出版商
Glinskii O, Huxley V, Xie L, Bunyak F, Palaniappan K, Glinsky V. Complex Non-sinus-associated Pachymeningeal Lymphatic Structures: Interrelationship With Blood Microvasculature. Front Physiol. 2019;10:1364 pubmed 出版商
Bonnardel J, T Jonck W, Gaublomme D, Browaeys R, Scott C, Martens L, et al. Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche. Immunity. 2019;51:638-654.e9 pubmed 出版商
Hsu M, Rayasam A, Kijak J, Choi Y, Harding J, Marcus S, et al. Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells. Nat Commun. 2019;10:229 pubmed 出版商
Lownik J, Luker A, Damle S, Cooley L, El Sayed R, Hutloff A, et al. ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses. J Immunol. 2017;199:2305-2315 pubmed 出版商
Yu P, Wilhelm K, Dubrac A, Tung J, Alves T, Fang J, et al. FGF-dependent metabolic control of vascular development. Nature. 2017;545:224-228 pubmed 出版商
Chucair Elliott A, Carr M, Carr D. Long-term consequences of topical dexamethasone treatment during acute corneal HSV-1 infection on the immune system. J Leukoc Biol. 2017;101:1253-1261 pubmed 出版商
Wang W, Wang H, Zhou X, Li X, Sun W, Dellinger M, et al. Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice. J Bone Miner Res. 2017;32:939-950 pubmed 出版商
Munger S, Davis M, Simon A. Defective lymphatic valve development and chylothorax in mice with a lymphatic-specific deletion of Connexin43. Dev Biol. 2017;421:204-218 pubmed 出版商
Gardenier J, Hespe G, Kataru R, Savetsky I, Torrisi J, Nores G, et al. Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema. JCI Insight. 2016;1:e84095 pubmed 出版商
Liang Q, Ju Y, Chen Y, Wang W, Li J, Zhang L, et al. Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice. Arthritis Res Ther. 2016;18:62 pubmed 出版商
Munger S, Geng X, Srinivasan R, Witte M, Paul D, Simon A. Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016;412:173-90 pubmed 出版商
Martínez Corral I, Ulvmar M, Stanczuk L, Tatin F, Kizhatil K, John S, et al. Nonvenous origin of dermal lymphatic vasculature. Circ Res. 2015;116:1649-54 pubmed 出版商
Bénézech C, Nayar S, Finney B, Withers D, Lowe K, Desanti G, et al. CLEC-2 is required for development and maintenance of lymph nodes. Blood. 2014;123:3200-7 pubmed 出版商
Cogger V, Svistounov D, Warren A, Zykova S, Melvin R, Solon Biet S, et al. Liver aging and pseudocapillarization in a Werner syndrome mouse model. J Gerontol A Biol Sci Med Sci. 2014;69:1076-86 pubmed 出版商
Salnikova O, Breuhahn K, Hartmann N, Schmidt J, Ryschich E. Endothelial plasticity governs the site-specific leukocyte recruitment in hepatocellular cancer. Int J Cancer. 2013;133:2372-82 pubmed 出版商
Miller C, Hartigan O Connor D, Lee M, Laidlaw G, Cornelissen I, Matloubian M, et al. IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. Int Immunol. 2013;25:471-83 pubmed 出版商
Corbitt N, Kimura S, Isse K, Specht S, Chedwick L, Rosborough B, et al. Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation. Am J Pathol. 2013;182:180-91 pubmed 出版商
Baptista A, Olivier B, Goverse G, Greuter M, Knippenberg M, Kusser K, et al. Colonic patch and colonic SILT development are independent and differentially regulated events. Mucosal Immunol. 2013;6:511-21 pubmed 出版商
Joo H, Choi D, Lim J, Park J, Lee S, Song S, et al. ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells. Blood. 2012;120:2733-44 pubmed
Nakayama Y, Bromberg J. Lymphotoxin-beta receptor blockade induces inflammation and fibrosis in tolerized cardiac allografts. Am J Transplant. 2012;12:2322-34 pubmed 出版商
Yin N, Zhang N, Lal G, Xu J, Yan M, Ding Y, et al. Lymphangiogenesis is required for pancreatic islet inflammation and diabetes. PLoS ONE. 2011;6:e28023 pubmed 出版商
Vigl B, Aebischer D, Nitschké M, Iolyeva M, Röthlin T, Antsiferova O, et al. Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner. Blood. 2011;118:205-15 pubmed 出版商
Furuya M, Kirschbaum S, Paulovich A, Pauli B, Zhang H, Alexander J, et al. Lymphatic endothelial murine chloride channel calcium-activated 1 is a ligand for leukocyte LFA-1 and Mac-1. J Immunol. 2010;185:5769-77 pubmed 出版商
Harada K, Yamazaki T, Iwata C, Yoshimatsu Y, Sase H, Mishima K, et al. Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis. J Cell Sci. 2009;122:3923-30 pubmed 出版商
Zumsteg A, Baeriswyl V, Imaizumi N, Schwendener R, Ruegg C, Christofori G. Myeloid cells contribute to tumor lymphangiogenesis. PLoS ONE. 2009;4:e7067 pubmed 出版商
Luong M, Tam J, Lin Q, Hagendoorn J, Moore K, Padera T, et al. Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice. J Cell Physiol. 2009;219:430-7 pubmed 出版商
Jiang S, Bailey A, Goldman D, Swain J, Wong M, Streeter P, et al. Hematopoietic stem cells contribute to lymphatic endothelium. PLoS ONE. 2008;3:e3812 pubmed 出版商
Hirashima M, Sano K, Morisada T, Murakami K, Rossant J, Suda T. Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Dev Biol. 2008;316:149-59 pubmed 出版商
Mishima K, Watabe T, Saito A, Yoshimatsu Y, Imaizumi N, Masui S, et al. Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades. Mol Biol Cell. 2007;18:1421-9 pubmed
Hamaguchi I, Morisada T, Azuma M, Murakami K, Kuramitsu M, Mizukami T, et al. Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoietic cell survival. Blood. 2006;107:1207-13 pubmed
Morisada T, Oike Y, Yamada Y, Urano T, Akao M, Kubota Y, et al. Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation. Blood. 2005;105:4649-56 pubmed
产品信息
产品类型 :
抗体
产品名称 :
LYVE1 Monoclonal Antibody (ALY7), eFluor™ 660, eBioscience
目录# :
50-0443-82
规格 :
100微克
定价 :
美国388
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1-10 µg/mL, Immunohistochemistry (Frozen): 1-10 µg/mL
物种 :
小鼠
克隆 :
ALY7
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module, the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves. LYVE1 is a type I integral membrane glycoprotein. LYVE-1 is expressed primarily on lymphatic vessel endothelium and is likely to be involved in regulating the traffic of leucocytes and tumor cells to lymph nodes. The lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen. A number of molecules have been identified as markers for lymphatic endothelium which include LYVE1, PALE, VEGFR3, and podoplanin. Diseases associated with LYVE1 dysfunction includes Complete Androgen Insensitivity Syndrome.
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1-10 µg/mL, Immunohistochemistry (Frozen): 1-10 µg/mL
别名 :
1200012G08Rik; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; CRSBP1; CRSBP-1; extra cellular link domain-containing 1; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; HAR; hyaluronic acid receptor; lymphatic endothelial hyaluronan receptor LYVE-1; lymphatic vessel endothelial HA receptor-1; lymphatic vessel endothelial HA recptor-1; lymphatic vessel endothelial hyaluronan receptor 1; lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1; LYVE-1; sLyve 1; sLyve1; soluble LYVE 1; soluble LYVE1; UNQ230/PRO263; XLKD1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国