产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IRF5 Monoclonal Antibody (ALYSCLN), eFluor 660, eBioscience™
目录 :
50-9698-42
规格 :
100Tests
价格 :
美国459
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
efluor 660
克隆名称 :
ALYSCLN
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 5
参考文献
Wei Z, Yan L, Chen Y, Bao C, Deng J, Deng J. Mangiferin inhibits macrophage classical activation via downregulating interferon regulatory factor 5 expression. Mol Med Rep. 2016;14:1091-8 pubmed 出版商
Krausgruber T, Blazek K, Smallie T, Alzabin S, Lockstone H, Sahgal N, et al. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol. 2011;12:231-8 pubmed 出版商
Savitsky D, Yanai H, Tamura T, Taniguchi T, Honda K. Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus. Proc Natl Acad Sci U S A. 2010;107:10154-9 pubmed 出版商
Mancl M, Hu G, Sangster Guity N, Olshalsky S, Hoops K, Fitzgerald Bocarsly P, et al. Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function. J Biol Chem. 2005;280:21078-90 pubmed
Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, et al. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature. 2005;434:243-9 pubmed
产品信息
产品类型 :
抗体
产品名称 :
IRF5 Monoclonal Antibody (ALYSCLN), eFluor 660, eBioscience™
目录# :
50-9698-42
规格 :
100Tests
价格 :
美国459
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µL (0.25 µg)/test
物种 :
人类
克隆 :
ALYSCLN
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.25 µg)/test
别名 :
AW491843;干扰素调节因子5;干扰素调节因子5骨髓;Irf5;IRF-5;mirf5;OTTHUMP00000212907;SLEB10
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国