产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
SMAD3多克隆抗体
目录 :
51-1500
规格 :
100微克
价格 :
425美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:250; 图 4a
  • 免疫印迹; 小鼠; 图 4b
Chowdhury A, Hasselbach L, Echtermeyer F, Jyotsana N, Theilmeier G, Herzog C. Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts. Sci Rep. 2017;7:42725 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 7b
Zhu Y, Takayama T, Wang B, Kent A, Zhang M, Binder B, et al. Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol. Sci Rep. 2017;7:41916 pubmed 出版商
  • 免疫印迹; 人类; 图 3f
Lefort K, Ostano P, Mello Grand M, Calpini V, Scatolini M, Farsetti A, et al. Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer. Oncotarget. 2016;7:48011-48026 pubmed 出版商
Devocelle A, Lecru L, Francois H, Desterke C, Gallerne C, Eid P, et al. Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis. Int J Cell Biol. 2019;2019:9151394 pubmed 出版商
Oh S, Shin S, Song H, Grande J, Janknecht R. Relationship between ETS Transcription Factor ETV1 and TGF-β-regulated SMAD Proteins in Prostate Cancer. Sci Rep. 2019;9:8186 pubmed 出版商
Xu H, Li F. miR‑127 aggravates myocardial failure by promoting the TGF‑β1/Smad3 signaling. Mol Med Rep. 2018;18:4839-4846 pubmed 出版商
Albers R, Selesniemi K, Natale D, Brown T. TGF-β induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation. Int J Stem Cells. 2018;11:111-120 pubmed 出版商
Feng M, Tang P, Huang X, Sun S, You Y, Xiao J, et al. TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis. Mol Ther. 2018;26:148-161 pubmed 出版商
Sakr S, Abdulfatah E, Thomas S, Al Wahab Z, Beydoun R, Morris R, et al. Granulosa Cell Tumors: Novel Predictors of Recurrence in Early-stage Patients. Int J Gynecol Pathol. 2017;36:240-252 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
SMAD3多克隆抗体
目录# :
51-1500
规格 :
100微克
价格 :
425美元
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类
应用 :
ChIP assay: 2 µg/10^6 cells, ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry: 1.0 µg/mL, Western Blot: 1-3 µg/mL
物种 :
人类
抗体亚型 :
IgG
储存 :
-20°C
描述 :
SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
免疫原 :
A 20 amino acid synthetic peptide derived from a central portion of the linker domain of human Smad3
格式 :
液体
应用w/稀释 :
ChIP assay: 2 µg/10^6 cells, ELISA: 0.1-1.0 µg/mL, Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry: 1.0 µg/mL, Western Blot: 1-3 µg/mL
别名 :
AU022421; DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3a; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MAD-3; madh3; madh3a; madh3-A; MGC60396; mMad3; mothers against decapentaplegic homolog 3; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; Smad 3; SMAD family member 3; SMAD family member 3 L homeolog; SMAD family member 3a; SMAD, mothers against DPP homolog 3; Smad3; smad3.L; smad3a; TGF beta response effector Smad3; TGF-beta response effector Smad3; transcription factor; transcription factor Smad3; wu:fa99e03; XELAEV_18018454mg; XenMLP; Xmad3; XSmad3
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国