产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
水闸蛋白1多克隆抗体
目录 :
51-9000
规格 :
100微克
价格 :
美国419.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, , , pigs
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 54
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:100; 图 5a
Fayad R, Rojas M, Partisani M, Finetti P, Dib S, Abélanet S, et al. EFA6B regulates a stop signal for collective invasion in breast cancer. Nat Commun. 2021;12:2198 pubmed 出版商
  • 免疫印迹; 小鼠; 0.5 ug/ml; 图 6k
Break T, Oikonomou V, Dutzan N, Desai J, Swidergall M, Freiwald T, et al. Aberrant type 1 immunity drives susceptibility to mucosal fungal infections. Science. 2021;371: pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 3c
Pellegrini L, Bonfio C, Chadwick J, Begum F, Skehel M, Lancaster M. Human CNS barrier-forming organoids with cerebrospinal fluid production. Science. 2020;: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 6a
  • 免疫印迹; 小鼠; 1:200; 图 6b
Cox C, Lu R, Salcin K, Wilson J. The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation. Cell Mol Gastroenterol Hepatol. 2018;5:145-156 pubmed 出版商
  • 免疫细胞化学; 犬; 图 2
  • 免疫印迹; 犬; 图 2
Tokuda S, Hirai T, Furuse M. Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells. PLoS ONE. 2017;12:e0182521 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Mathieu A, Ohl Séguy E, Dubois M, Jean D, Jones C, Boudreau F, et al. Subcellular proteomics analysis of different stages of colorectal cancer cell lines. Proteomics. 2016;16:3009-3018 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s1d
Balusu S, Van Wonterghem E, De Rycke R, Raemdonck K, Stremersch S, Gevaert K, et al. Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles. EMBO Mol Med. 2016;8:1162-1183 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
  • 免疫印迹; 人类; 图 1
Yuki T, Tobiishi M, Kusaka Kikushima A, Ota Y, Tokura Y. Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17. PLoS ONE. 2016;11:e0161759 pubmed 出版商
  • 免疫印迹; 小鼠; 1:50; 图 4j
Wardill H, Bowen J, Van Sebille Y, Secombe K, Coller J, Ball I, et al. TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced Diarrhea. Mol Cancer Ther. 2016;15:2767-2779 pubmed
  • 免疫印迹; 犬; 1:1000; 图 3a
Ronaghan N, Shang J, Iablokov V, Zaheer R, Colarusso P, Dion S, et al. The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction. Am J Physiol Gastrointest Liver Physiol. 2016;311:G466-79 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
Maria O, Liu Y, El Hakim M, Zeitouni A, Tran S. The role of human fibronectin- or placenta basement membrane extract-based gels in favouring the formation of polarized salivary acinar-like structures. J Tissue Eng Regen Med. 2017;11:2643-2657 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2
Zoschke C, Ulrich M, Sochorová M, Wolff C, Vavrova K, Ma N, et al. The barrier function of organotypic non-melanoma skin cancer models. J Control Release. 2016;233:10-8 pubmed 出版商
  • 免疫印迹; pigs ; 1:1000; 表 6
Zhu H, Liu Y, Chen S, Wang X, Pi D, Leng W, et al. Fish oil enhances intestinal barrier function and inhibits corticotropin-releasing hormone/corticotropin-releasing hormone receptor 1 signalling pathway in weaned pigs after lipopolysaccharide challenge. Br J Nutr. 2016;115:1947-57 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2
Kacem M, Agili F, Tounsi H, Zribi H, Zaraa I, Mokni M, et al. Immunohistological study of tight junction protein expression in mal de Meleda. Ultrastruct Pathol. 2016;40:176-80 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3
Patkee W, Carr G, Baker E, Baines D, Garnett J. Metformin prevents the effects of Pseudomonas aeruginosa on airway epithelial tight junctions and restricts hyperglycaemia-induced bacterial growth. J Cell Mol Med. 2016;20:758-64 pubmed 出版商
  • 免疫细胞化学; 小鼠; 5 ug/ml; 图 2
Lazarevic I, Engelhardt B. Modeling immune functions of the mouse blood-cerebrospinal fluid barrier in vitro: primary rather than immortalized mouse choroid plexus epithelial cells are suited to study immune cell migration across this brain barrier. Fluids Barriers CNS. 2016;13:2 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 1
  • 免疫印迹; 大鼠; 1:1000; 图 3
Yang S, Krug S, Heitmann J, Hu L, Reinhold A, Sauer S, et al. Analgesic drug delivery via recombinant tissue plasminogen activator and microRNA-183-triggered opening of the blood-nerve barrier. Biomaterials. 2016;82:20-33 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Barbáchano A, Fernández Barral A, Pereira F, Segura M, Ordóñez Morán P, Carrillo de Santa Pau E, et al. SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene. 2016;35:2991-3003 pubmed 出版商
  • 免疫印迹; 鸡; 1:1000
Liu S, Zhao J, Fan X, Liu G, Jiao H, Wang X, et al. Rapamycin, a specific inhibitor of the target of rapamycin complex 1, disrupts intestinal barrier integrity in broiler chicks. J Anim Physiol Anim Nutr (Berl). 2016;100:323-30 pubmed 出版商
Liu Y, Xu Q, Wang Y, Liang T, Li X, Wang D, et al. Necroptosis is active and contributes to intestinal injury in a piglet model with lipopolysaccharide challenge. Cell Death Dis. 2021;12:62 pubmed 出版商
Shi H, Koronyo Y, Fuchs D, Sheyn J, Wawrowsky K, Lahiri S, et al. Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease. Acta Neuropathol Commun. 2020;8:202 pubmed 出版商
Chen Z, Chen G, Zhao H. FDPS promotes glioma growth and macrophage recruitment by regulating CCL20 via Wnt/β-catenin signalling pathway. J Cell Mol Med. 2020;24:9055-9066 pubmed 出版商
Chen L, Feng Z, Yuan G, Emerson C, Stewart P, Ye F, et al. Human Immunodeficiency Virus-Associated Exosomes Promote Kaposi's Sarcoma-Associated Herpesvirus Infection via the Epidermal Growth Factor Receptor. J Virol. 2020;94: pubmed 出版商
Sayoc Becerra A, Krishnan M, Fan S, Jimenez J, HERNANDEZ R, Gibson K, et al. The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction. Inflamm Bowel Dis. 2020;26:407-422 pubmed 出版商
Mehdizadeh Gohari I, Li J, Navarro M, Uzal F, McClane B. Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells. Toxins (Basel). 2019;11: pubmed 出版商
Miranda J, Martín Tapia D, Valdespino Vazquez Y, Alarcón L, Espejel Nuñez A, Guzmán Huerta M, et al. Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability. Cells. 2019;8: pubmed 出版商
Otani T, Nguyen T, Tokuda S, Sugihara K, Sugawara T, Furuse K, et al. Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity. J Cell Biol. 2019;218:3372-3396 pubmed 出版商
Yang R, Hui Q, Jiang Q, Liu S, Zhang H, Wu J, et al. Effect of Manitoba-Grown Red-Osier Dogwood Extracts on Recovering Caco-2 Cells from H2O2-Induced Oxidative Damage. Antioxidants (Basel). 2019;8: pubmed 出版商
Masterson J, Biette K, Hammer J, Nguyen N, Capocelli K, Saeedi B, et al. Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis. J Clin Invest. 2019;129:3224-3235 pubmed 出版商
Luo Y, Xu J, Zhang C, Jiang C, Ma Y, He H, et al. Toll-like receptor 5-mediated IL-17C expression in intestinal epithelial cells enhances epithelial host defense against F4+ ETEC infection. Vet Res. 2019;50:48 pubmed 出版商
Deissler H, Lang G, Lang G. Fate of the Fc fusion protein aflibercept in retinal endothelial cells: competition of recycling and degradation. Graefes Arch Clin Exp Ophthalmol. 2019;257:83-94 pubmed 出版商
Bashir M, Meddings J, Alshaikh A, Jung D, Le K, Amin R, et al. Enhanced gastrointestinal passive paracellular permeability contributes to the obesity-associated hyperoxaluria. Am J Physiol Gastrointest Liver Physiol. 2019;316:G1-G14 pubmed 出版商
Reinhold A, Schwabe J, Lux T, Salvador E, Rittner H. Quantitative and Microstructural Changes of the Blood-Nerve Barrier in Peripheral Neuropathy. Front Neurosci. 2018;12:936 pubmed 出版商
Zhang L, Wang X, Chen S, Wang S, Tu Z, Zhang G, et al. Medium-Chain Triglycerides Attenuate Liver Injury in Lipopolysaccharide-Challenged Pigs by Inhibiting Necroptotic and Inflammatory Signaling Pathways. Int J Mol Sci. 2018;19: pubmed 出版商
Jin Y, Ibrahim D, Magness S, Blikslager A. Knockout of ClC-2 reveals critical functions of adherens junctions in colonic homeostasis and tumorigenicity. Am J Physiol Gastrointest Liver Physiol. 2018;315:G966-G979 pubmed 出版商
Xu X, Chen S, Wang H, Tu Z, Wang S, Wang X, et al. Medium-chain TAG improve intestinal integrity by suppressing toll-like receptor 4, nucleotide-binding oligomerisation domain proteins and necroptosis signalling in weanling piglets challenged with lipopolysaccharide. Br J Nutr. 2018;119:1019-1028 pubmed 出版商
Riva L, Song O, Prentoe J, Helle F, L homme L, Gattolliat C, et al. Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry. J Virol. 2018;92: pubmed 出版商
Steeland S, Gorlé N, Vandendriessche C, Balusu S, Brkic M, Van Cauwenberghe C, et al. Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease. EMBO Mol Med. 2018;10: pubmed 出版商
Yamaga K, Murota H, Tamura A, Miyata H, Ohmi M, Kikuta J, et al. Claudin-3 Loss Causes Leakage of Sweat from the Sweat Gland to Contribute to the Pathogenesis of Atopic Dermatitis. J Invest Dermatol. 2018;138:1279-1287 pubmed 出版商
Cuellar P, Hernández Nava E, García Rivera G, Chavez Munguia B, Schnoor M, Betanzos A, et al. Entamoeba histolytica EhCP112 Dislocates and Degrades Claudin-1 and Claudin-2 at Tight Junctions of the Intestinal Epithelium. Front Cell Infect Microbiol. 2017;7:372 pubmed 出版商
Sauer R, Kirchner J, Yang S, Hu L, Leinders M, Sommer C, et al. Blood-spinal cord barrier breakdown and pericyte deficiency in peripheral neuropathy. Ann N Y Acad Sci. 2017;1405:71-88 pubmed 出版商
Zhu H, Pi D, Leng W, Wang X, HU C, Hou Y, et al. Asparagine preserves intestinal barrier function from LPS-induced injury and regulates CRF/CRFR signaling pathway. Innate Immun. 2017;23:546-556 pubmed 出版商
Kern M, Günzel D, Aschenbach J, Tedin K, Bondzio A, Lodemann U. Altered Cytokine Expression and Barrier Properties after In Vitro Infection of Porcine Epithelial Cells with Enterotoxigenic Escherichia coli and Probiotic Enterococcus faecium. Mediators Inflamm. 2017;2017:2748192 pubmed 出版商
Nighot P, Leung L, Ma T. Chloride channel ClC- 2 enhances intestinal epithelial tight junction barrier function via regulation of caveolin-1 and caveolar trafficking of occludin. Exp Cell Res. 2017;352:113-122 pubmed 出版商
Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed 出版商
Baruch K, Rosenzweig N, Kertser A, Deczkowska A, Sharif A, Spinrad A, et al. Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology. Nat Commun. 2015;6:7967 pubmed 出版商
Goichon A, Bertrand J, Chan P, Lecleire S, Coquard A, Cailleux A, et al. Enteral delivery of proteins enhances the expression of proteins involved in the cytoskeleton and protein biosynthesis in human duodenal mucosa. Am J Clin Nutr. 2015;102:359-67 pubmed 出版商
Lu Z, Kim D, Fan J, Lu Q, Verbanac K, Ding L, et al. A non-tight junction function of claudin-7-Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment. Mol Cancer. 2015;14:120 pubmed 出版商
Staat C, Coisne C, Dabrowski S, Stamatovic S, Andjelkovic A, Wolburg H, et al. Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers. Biomaterials. 2015;54:9-20 pubmed 出版商
Ghersi Egea J, Babikian A, Blondel S, Strazielle N. Changes in the cerebrospinal fluid circulatory system of the developing rat: quantitative volumetric analysis and effect on blood-CSF permeability interpretation. Fluids Barriers CNS. 2015;12:8 pubmed 出版商
Tokuda S, Furuse M. Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells. PLoS ONE. 2015;10:e0119869 pubmed 出版商
Watari A, Hashegawa M, Yagi K, Kondoh M. Homoharringtonine increases intestinal epithelial permeability by modulating specific claudin isoforms in Caco-2 cell monolayers. Eur J Pharm Biopharm. 2015;89:232-8 pubmed 出版商
Casselbrant A, Elias E, Fändriks L, Wallenius V. Expression of tight-junction proteins in human proximal small intestinal mucosa before and after Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis. 2015;11:45-53 pubmed 出版商
Retana C, Sanchez E, Perez Lopez A, Cruz A, Lagunas J, Cruz C, et al. Alterations of intercellular junctions in peritoneal mesothelial cells from patients undergoing dialysis: effect of retinoic Acid. Perit Dial Int. 2015;35:275-87 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
水闸蛋白1多克隆抗体
目录# :
51-9000
规格 :
100微克
价格 :
美国419.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
鸡, 人类, 大鼠
应用 :
ELISA: 0.1-1.0 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 0.25 - 2 µg/mL
物种 :
鸡, 人类, 大鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
免疫原 :
Synthetic peptide derived from the C-terminus of the human Claudin-1 protein
格式 :
液体
应用w/稀释 :
ELISA: 0.1-1.0 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 0.25 - 2 µg/mL
别名 :
AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国