产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Podoplanin Monoclonal Antibody (eBio8.1.1 (8.1.1)), Alexa Fluor™ 488, eBioscience
目录 :
53-5381-80
规格 :
25微克
价格 :
美国182
克隆性 :
单克隆
宿主 :
Syrian golden hamster
共轭标签 :
AF488
克隆名称 :
eBio8.1。 1(8.1。 1)
反应物种 :
小鼠
应用 :
免疫组化, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 31
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500; 图 s1
Cloonan S, Glass K, Laucho Contreras M, Bhashyam A, Cervo M, Pabón M, et al. Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice. Nat Med. 2016;22:163-74 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100
Funakoshi S, Shimizu T, Numata O, Ato M, Melchers F, Ohnishi K. BILL-cadherin/cadherin-17 contributes to the survival of memory B cells. PLoS ONE. 2015;10:e0117566 pubmed 出版商
Tang C, Wang L, Sheng Y, Zheng Z, Xie Z, Wu F, et al. CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice. Theranostics. 2021;11:9791-9804 pubmed 出版商
de Winde C, Makris S, Millward L, Cantoral Rebordinos J, Benjamin A, Mart xed nez V, et al. Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9. J Cell Sci. 2021;134: pubmed 出版商
Prados A, Onder L, Cheng H, Mörbe U, Lütge M, Gil Cruz C, et al. Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity. Nat Immunol. 2021;22:510-519 pubmed 出版商
Thacker V, Dhar N, Sharma K, Barrile R, Karalis K, McKinney J. A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth. elife. 2020;9: pubmed 出版商
Fujimoto N, He Y, D Addio M, Tacconi C, Detmar M, Dieterich L. Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes. PLoS Biol. 2020;18:e3000704 pubmed 出版商
Jafree D, Moulding D, Kolatsi Joannou M, Perretta Tejedor N, Price K, Milmoe N, et al. Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease. elife. 2019;8: pubmed 出版商
Camara A, Cordeiro O, Alloush F, Sponsel J, Chypre M, Onder L, et al. Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche. Immunity. 2019;50:1467-1481.e6 pubmed 出版商
Riemondy K, Jansing N, Jiang P, Redente E, Gillen A, Fu R, et al. Single cell RNA sequencing identifies TGFβ as a key regenerative cue following LPS-induced lung injury. JCI Insight. 2019;5: pubmed 出版商
Hsu M, Rayasam A, Kijak J, Choi Y, Harding J, Marcus S, et al. Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells. Nat Commun. 2019;10:229 pubmed 出版商
Schlereth K, Weichenhan D, Bauer T, Heumann T, Giannakouri E, Lipka D, et al. The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium. elife. 2018;7: pubmed 出版商
Ogawa T, Li Y, Lua I, Hartner A, Asahina K. Isolation of a unique hepatic stellate cell population expressing integrin α8 from embryonic mouse livers. Dev Dyn. 2018;247:867-881 pubmed 出版商
Obulkasim H, Shi X, Wang J, Li J, Dai B, Wu P, et al. Podoplanin is an important stromal prognostic marker in perihilar cholangiocarcinoma. Oncol Lett. 2018;15:137-146 pubmed 出版商
Wang C, Liu P, Luo J, Ding H, Gao Y, Sun L, et al. Geldanamycin Reduces Acute Respiratory Distress Syndrome and Promotes the Survival of Mice Infected with the Highly Virulent H5N1 Influenza Virus. Front Cell Infect Microbiol. 2017;7:267 pubmed 出版商
de Aguiar Vallim T, Lee E, Merriott D, Goulbourne C, Cheng J, Cheng A, et al. ABCG1 regulates pulmonary surfactant metabolism in mice and men. J Lipid Res. 2017;58:941-954 pubmed 出版商
Gurung H, Carr M, Carr D. Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1. Immunol Cell Biol. 2017;95:87-98 pubmed 出版商
Blanco S, Bandiera R, Popis M, Hussain S, Lombard P, Aleksic J, et al. Stem cell function and stress response are controlled by protein synthesis. Nature. 2016;534:335-40 pubmed 出版商
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Loder S, Agarwal S, Sorkin M, Breuler C, Li J, Peterson J, et al. Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification. Ann Surg. 2016;264:1174-1180 pubmed
Pratama A, Srivastava M, Williams N, Papa I, Lee S, Dinh X, et al. MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres. Nat Commun. 2015;6:6436 pubmed 出版商
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Ballet R, Emre Y, Jemelin S, Charmoy M, Tacchini Cottier F, Imhof B. Blocking junctional adhesion molecule C enhances dendritic cell migration and boosts the immune responses against Leishmania major. PLoS Pathog. 2014;10:e1004550 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
Podoplanin Monoclonal Antibody (eBio8.1.1 (8.1.1)), Alexa Fluor™ 488, eBioscience
目录# :
53-5381-80
规格 :
25微克
价格 :
美国182
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
Syrian Hamster
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test
物种 :
小鼠
克隆 :
eBio8.1。 1(8.1。 1)
抗体亚型 :
IgG
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight. Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue. Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells. Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC. Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm. Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test
别名 :
29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国