产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GFAP Monoclonal Antibody (GA5), Alexa Fluor™ 488, eBioscience
目录 :
53-9892-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF488
克隆名称 :
GA5
反应物种 :
人类, 小鼠, 大鼠, , pigs , domestic rabbit
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 39
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 大鼠; 1:200; 图 2e
Singh L, Devi T. Potential Combination Drug Therapy to Prevent Redox Stress and Mitophagy Dysregulation in Retinal Müller Cells under High Glucose Conditions: Implications for Diabetic Retinopathy. Diseases. 2021;9: pubmed 出版商
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Obara K, Shirai K, Hamada Y, Arakawa N, Hasegawa A, Takaoka N, et al. Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model. PLoS ONE. 2023;18:e0280304 pubmed 出版商
Wood J, Wong E, Joghee R, Balbaa A, Vitanova K, Stringer K, et al. Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology. Cell Rep. 2022;41:111686 pubmed 出版商
Xuan F, Yan L, Li Y, Fan F, Deng H, Gou M, et al. Glial receptor PLXNB2 regulates schizophrenia-related stress perception via the amygdala. Front Immunol. 2022;13:1005067 pubmed 出版商
Zhang Q, Abdo R, Iosef C, Kaneko T, Cecchini M, Han V, et al. The spatial transcriptomic landscape of non-small cell lung cancer brain metastasis. Nat Commun. 2022;13:5983 pubmed 出版商
Battistella E, Schniete J, Wesencraft K, Quintana J, McConnell G. Light-sheet mesoscopy with the Mesolens provides fast sub-cellular resolution imaging throughout large tissue volumes. iScience. 2022;25:104797 pubmed 出版商
Garcia Serrano A, Mohr A, Philippe J, Skoug C, Sp xe9 gel P, Duarte J. Cognitive Impairment and Metabolite Profile Alterations in the Hippocampus and Cortex of Male and Female Mice Exposed to a Fat and Sugar-Rich Diet are Normalized by Diet Reversal. Aging Dis. 2022;13:267-283 pubmed 出版商
Krasemann S, Haferkamp U, Pfefferle S, Woo M, Heinrich F, Schweizer M, et al. The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2. Stem Cell Reports. 2022;17:307-320 pubmed 出版商
Gosnell M, Staikopoulos V, Anwer A, Mahbub S, Hutchinson M, Mustafa S, et al. Autofluorescent imprint of chronic constriction nerve injury identified by deep learning. Neurobiol Dis. 2021;160:105528 pubmed 出版商
Marini C, Cossu V, Kumar M, Milanese M, Cortese K, Bruno S, et al. The Role of Endoplasmic Reticulum in the Differential Endurance against Redox Stress in Cortical and Spinal Astrocytes from the Newborn SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis. Antioxidants (Basel). 2021;10: pubmed 出版商
McAlpine C, Park J, Griciuc A, Kim E, Choi S, Iwamoto Y, et al. Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease. Nature. 2021;595:701-706 pubmed 出版商
Gratuze M, Chen Y, Parhizkar S, Jain N, Strickland M, Serrano J, et al. Activated microglia mitigate Aβ-associated tau seeding and spreading. J Exp Med. 2021;218: pubmed 出版商
Wu J, Chen N, Liu Y, Godlewski G, Kaplan H, Shrader S, et al. Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia. PLoS ONE. 2021;16:e0251677 pubmed 出版商
Gebril H, Wahba A, Zhou X, Lai T, Alharfoush E, Dicicco Bloom E, et al. Developmental Role of Adenosine Kinase in the Cerebellum. Eneuro. 2021;8: pubmed 出版商
. CSF SERPINA3 Levels Are Elevated in Patients With Progressive MS. Neurol Neuroimmunol Neuroinflamm. 2021;8: pubmed 出版商
Borggrewe M, Grit C, Vainchtein I, Brouwer N, Wesseling E, Laman J, et al. Regionally diverse astrocyte subtypes and their heterogeneous response to EAE. Glia. 2021;69:1140-1154 pubmed 出版商
Lee E, Winston Gray C, Barlow J, Rissman R, Jeste D. Plasma Levels of Neuron- and Astrocyte-Derived Exosomal Amyloid Beta1-42, Amyloid Beta1-40, and Phosphorylated Tau Levels in Schizophrenia Patients and Non-psychiatric Comparison Subjects: Relationships With Cognitive Functioning and Psychopathology. Front Psychiatry. 2020;11:532624 pubmed 出版商
Martins C, Neves L, de Oliveira M, Bagatini P, Barboza R, Mestriner R, et al. Neuroprotective effect of ACTH on collagenase-induced peri-intraventricular hemorrhage in newborn male rats. Sci Rep. 2020;10:17734 pubmed 出版商
Upadhyay M, Milliner C, Bell B, Bonilha V. Oxidative stress in the retina and retinal pigment epithelium (RPE): Role of aging, and DJ-1. Redox Biol. 2020;:101623 pubmed 出版商
Liu J, Zhu Y, Guo Y, Lin L, Wang Z, Gu F, et al. Inhibition of GSK3β and RIP1K Attenuates Glial Scar Formation Induced by Ischemic Stroke via Reduction of Inflammatory Cytokine Production. Front Pharmacol. 2020;11:812 pubmed 出版商
Oh J, Hwang T, Jang J, Park J, Ryu Y, Lee H, et al. Muscovite nanoparticles mitigate neuropathic pain by modulating the inflammatory response and neuroglial activation in the spinal cord. Neural Regen Res. 2020;15:2162-2168 pubmed 出版商
Rayaprolu S, Gao T, Xiao H, Ramesha S, Weinstock L, Shah J, et al. Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease. Mol Neurodegener. 2020;15:28 pubmed 出版商
Hong S, Bullert A, Baker M, Choi D. Astrocytic equilibrative nucleoside transporter type 1 upregulations in the dorsomedial and dorsolateral striatum distinctly coordinate goal-directed and habitual ethanol-seeking behaviours in mice. Eur J Neurosci. 2020;52:3110-3123 pubmed 出版商
Kosuge Y, Kaneko E, Nango H, Miyagishi H, Ishige K, Ito Y. Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis. Oxid Med Cell Longev. 2020;2020:1020673 pubmed 出版商
Parekh R, Robidoux J, Sriramula S. Kinin B1 Receptor Blockade Prevents Angiotensin II-induced Neuroinflammation and Oxidative Stress in Primary Hypothalamic Neurons. Cell Mol Neurobiol. 2020;40:845-857 pubmed 出版商
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Telias M, Denlinger B, Helft Z, Thornton C, Beckwith Cohen B, Kramer R. Retinoic Acid Induces Hyperactivity, and Blocking Its Receptor Unmasks Light Responses and Augments Vision in Retinal Degeneration. Neuron. 2019;102:574-586.e5 pubmed 出版商
Yan J, Zhao Q, Gabrusiewicz K, Kong L, Xia X, Wang J, et al. FGL2 promotes tumor progression in the CNS by suppressing CD103+ dendritic cell differentiation. Nat Commun. 2019;10:448 pubmed 出版商
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Wu L, Ye Z, Zhou C, Wang C, Xie G, Zhang X, et al. Roles of Pannexin-1 Channels in Inflammatory Response through the TLRs/NF-Kappa B Signaling Pathway Following Experimental Subarachnoid Hemorrhage in Rats. Front Mol Neurosci. 2017;10:175 pubmed 出版商
Jin W, Shi S, Li Z, Li M, Wood K, Gonzales R, et al. Depletion of microglia exacerbates postischemic inflammation and brain injury. J Cereb Blood Flow Metab. 2017;37:2224-2236 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
GFAP Monoclonal Antibody (GA5), Alexa Fluor™ 488, eBioscience
目录# :
53-9892-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
鸡, 人类, 小鼠, 猪, 兔, 大鼠
应用 :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Frozen): 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL
物种 :
鸡, 人类, 小鼠, 猪, 兔, 大鼠
克隆 :
GA5
抗体亚型 :
IgG1
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent, Immunocytochemistry: 10 µg/mL, Immunohistochemistry (Frozen): 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL
别名 :
6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国