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domestic rabbit
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豚鼠, 人类, 小鼠, 大鼠, , pigs , 斑马鱼, domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
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文章摘录数: 383
  • 免疫细胞化学; pigs ; 1:100; 图 3
Bernardini C, La Mantia D, Salaroli R, Zannoni A, Nauwelaerts N, Deferm N, et al. Development of a Pig Mammary Epithelial Cell Culture Model as a Non-Clinical Tool for Studying Epithelial Barrier-A Contribution from the IMI-ConcePTION Project. Animals (Basel). 2021;11: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 s2c
Huang Y, Chu P, Chen J, Huang C, Huang C, Tsai Y, et al. Expression pattern and prognostic impact of glycoprotein non-metastatic B (GPNMB) in triple-negative breast cancer. Sci Rep. 2021;11:12171 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 2a
Hanke Gogokhia C, Lehmann G, Benedicto I, de la Fuente Ortega E, Arshavsky V, Schreiner R, et al. Apical CLC-2 in retinal pigment epithelium is crucial for survival of the outer retina. FASEB J. 2021;35:e21689 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4a
Park N, Shetye S, Bogush I, Keene D, Tufa S, Hudson D, et al. Reticulocalbin 3 is involved in postnatal tendon development by regulating collagen fibrillogenesis and cellular maturation. Sci Rep. 2021;11:10868 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 4a
  • 免疫印迹; 小鼠; 图 4b
Liu M, Rao H, Liu J, Li X, Feng W, Gui L, et al. The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis. Redox Biol. 2021;43:102004 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2e
Ngamsri K, Gamper Tsigaras J, Reutershan J, Konrad F. Fractalkine Is Linked to the Necrosome Pathway in Acute Pulmonary Inflammation. Front Med (Lausanne). 2021;8:591790 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 1a
Tang C, Han J, Dalvi S, Manian K, Winschel L, Volland S, et al. A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor-RPE interface. Commun Biol. 2021;4:161 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 8e
Devraj G, Guérit S, Seele J, Spitzer D, Macas J, Khel M, et al. HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis. Acta Neuropathol. 2020;140:183-208 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4f
Peroutka R, Buzza M, Mukhopadhyay S, Johnson T, Driesbaugh K, Antalis T. Testisin/Prss21 deficiency causes increased vascular permeability and a hemorrhagic phenotype during luteal angiogenesis. PLoS ONE. 2020;15:e0234407 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7i
Kang L, Yu H, Yang X, Zhu Y, Bai X, Wang R, et al. Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke. Nat Commun. 2020;11:2488 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 2h
Salido E, Ramamurthy V. Proteoglycan IMPG2 Shapes the Interphotoreceptor Matrix and Modulates Vision. J Neurosci. 2020;40:4059-4072 pubmed 出版商
  • 免疫组化; 小鼠; 图 s2b
Trevisan A, Bauer M, Brindley R, Currie K, Carter B. Jedi-1 deficiency increases sensory neuron excitability through a non-cell autonomous mechanism. Sci Rep. 2020;10:1300 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1d
Marin Navarro A, Pronk R, van der Geest A, Oliynyk G, Nordgren A, Arsenian Henriksson M, et al. p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids. Cell Death Dis. 2020;11:52 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:150; 图 2a
Bertrand L, Méroth F, Tournebize M, Leda A, Sun E, Toborek M. Targeting the HIV-infected brain to improve ischemic stroke outcome. Nat Commun. 2019;10:2009 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1c
Ferraro D, Patella F, Zanivan S, Donato C, Aceto N, Giannotta M, et al. Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cells. BMC Cancer. 2019;19:312 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 2d
Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai M, Nomura E, et al. Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells. Cell Mol Gastroenterol Hepatol. 2019;7:135-156 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 ev1b
Feldner A, Adam M, Tetzlaff F, Moll I, Komljenovic D, Sahm F, et al. Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice. EMBO Mol Med. 2017;9:890-905 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:300; 图 s4a
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Yanagida K, Liu C, Faraco G, Galvani S, Smith H, Burg N, et al. Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. Proc Natl Acad Sci U S A. 2017;114:4531-4536 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2b
Samuel W, Jaworski C, Postnikova O, Kutty R, Duncan T, Tan L, et al. Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. Mol Vis. 2017;23:60-89 pubmed
  • 免疫细胞化学; 小鼠; 图 1a
Balmer D, Bapst Wicht L, Pyakurel A, Emery M, Nanchen N, Bochet C, et al. Bis-Retinoid A2E Induces an Increase of Basic Fibroblast Growth Factor via Inhibition of Extracellular Signal-Regulated Kinases 1/2 Pathway in Retinal Pigment Epithelium Cells and Facilitates Phagocytosis. Front Aging Neurosci. 2017;9:43 pubmed 出版商
  • 免疫组化; 人类; 1:500; 图 2A
Geng Z, Walsh P, Truong V, Hill C, Ebeling M, Kapphahn R, et al. Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS ONE. 2017;12:e0173575 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4f
Tung K, Harakal J, Qiao H, Rival C, Li J, Paul A, et al. Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance. J Clin Invest. 2017;127:1046-1060 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:25; 图 8b
Zhang J, Chen S, Cai J, Hou Z, Wang X, Kachelmeier A, et al. Culture media-based selection of endothelial cells, pericytes, and perivascular-resident macrophage-like melanocytes from the young mouse vestibular system. Hear Res. 2017;345:10-22 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:200; 图 5X'
Kozlovskaja GumbrienÄ— A, Yi R, Alexander R, Aman A, Jiskra R, Nagelberg D, et al. Proliferation-independent regulation of organ size by Fgf/Notch signaling. elife. 2017;6: pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 s2f
Priya R, Liang X, Teo J, Duszyc K, Yap A, Gomez G. ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Mol Biol Cell. 2017;28:12-20 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4b
  • 免疫印迹; 人类; 1:1000; 表 3
Sivagurunathan S, Palanisamy K, Arunachalam J, Chidambaram S. Possible role of HIWI2 in modulating tight junction proteins in retinal pigment epithelial cells through Akt signaling pathway. Mol Cell Biochem. 2017;427:145-156 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:250; 图 7a
  • 免疫印迹; 大鼠; 1:1000; 图 7g
Cao X, Shen L, Wu S, Yan C, Zhou Y, Xiong G, et al. Urban fine particulate matter exposure causes male reproductive injury through destroying blood-testis barrier (BTB) integrity. Toxicol Lett. 2017;266:1-12 pubmed 出版商
  • 免疫细胞化学; domestic rabbit; 1:100; 图 6a
Martínez Rendón J, Sánchez Guzmán E, Rueda A, González J, Gulias Cañizo R, Aquino Jarquin G, et al. TRPV4 Regulates Tight Junctions and Affects Differentiation in a Cell Culture Model of the Corneal Epithelium. J Cell Physiol. 2017;232:1794-1807 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7b
Chehaibi K, le Maire L, Bradoni S, Escolà J, Blanco Vaca F, Slimane M. Effect of PPAR-β/δ agonist GW0742 treatment in the acute phase response and blood-brain barrier permeability following brain injury. Transl Res. 2017;182:27-48 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 3b
  • 免疫印迹; 大鼠; 1:250; 图 3a
Gao Y, Mruk D, Chen H, Lui W, Lee W, Cheng C. Regulation of the blood-testis barrier by a local axis in the testis: role of laminin ?2 in the basement membrane. FASEB J. 2017;31:584-597 pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 6a
  • 免疫印迹; 小鼠; 1:500; 图 6b
Gautam J, Zhang X, Yao Y. The role of pericytic laminin in blood brain barrier integrity maintenance. Sci Rep. 2016;6:36450 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5a
Keppner A, Malsure S, Nobile A, Auberson M, Bonny O, Hummler E. Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis. Inflamm Bowel Dis. 2016;22:2824-2839 pubmed
  • 免疫细胞化学; 犬; 图 7a
Fujii N, Matsuo Y, Matsunaga T, Endo S, Sakai H, Yamaguchi M, et al. Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells. J Biol Chem. 2016;291:24787-24799 pubmed
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2c
Choi Y, Maki T, Mandeville E, Koh S, Hayakawa K, Arai K, et al. Dual effects of carbon monoxide on pericytes and neurogenesis in traumatic brain injury. Nat Med. 2016;22:1335-1341 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 3d
Feng X, Zhang D, Wang Y, Fan R, Hong F, Zhang Y, et al. Dopamine enhances duodenal epithelial permeability via the dopamine D5 receptor in rodent. Acta Physiol (Oxf). 2017;220:113-123 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 5c
Priya R, Wee K, Budnar S, Gomez G, Yap A, Michael M. Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II. Cell Cycle. 2016;15:3033-3041 pubmed
  • 免疫细胞化学; 小鼠; 图 s1b
Balusu S, Van Wonterghem E, De Rycke R, Raemdonck K, Stremersch S, Gevaert K, et al. Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles. EMBO Mol Med. 2016;8:1162-1183 pubmed 出版商
  • 免疫组化; 小鼠; 7 ug/ml; 表 s5
  • 免疫印迹; 小鼠; 2 ug/ml; 表 s5
de Sousa Rodrigues M, Bekhbat M, Houser M, Chang J, Walker D, Jones D, et al. Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice. Brain Behav Immun. 2017;59:158-172 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 7c
Wegwitz F, Lenfert E, Gerstel D, von Ehrenstein L, Einhoff J, Schmidt G, et al. CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo. Oncotarget. 2016;7:63730-63746 pubmed 出版商
  • 免疫印迹; 小鼠; 1:250; 图 7a
Lan A, Blais A, Coelho D, Capron J, Maarouf M, Benamouzig R, et al. Dual effects of a high-protein diet on DSS-treated mice during colitis resolution phase. Am J Physiol Gastrointest Liver Physiol. 2016;311:G624-G633 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 表 1
  • 免疫印迹; 大鼠; 1:500; 表 1
Li N, Lee W, Cheng C. Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier. Spermatogenesis. 2016;6:e1206353 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 2a
  • 免疫印迹; 小鼠; 1:40; 图 4k
Wardill H, Bowen J, Van Sebille Y, Secombe K, Coller J, Ball I, et al. TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced Diarrhea. Mol Cancer Ther. 2016;15:2767-2779 pubmed
  • 免疫细胞化学; 人类; 1:100; 图 3h
Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1a
  • 免疫印迹; 人类; 图 1d
Wilkinson E, Sidaway J, Cross M. Cardiotoxic drugs Herceptin and doxorubicin inhibit cardiac microvascular endothelial cell barrier formation resulting in increased drug permeability. Biol Open. 2016;5:1362-1370 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 2a
Thomsen M, Birkelund S, Burkhart A, Stensballe A, Moos T. Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier. J Neurochem. 2017;140:741-754 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 4
  • 免疫印迹; 大鼠; 1:500; 图 2
Li N, Mruk D, Chen H, Wong C, Lee W, Cheng C. Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43. Sci Rep. 2016;6:29667 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2
Iwasaki Y, Sugita S, Mandai M, Yonemura S, Onishi A, Ito S, et al. Differentiation/Purification Protocol for Retinal Pigment Epithelium from Mouse Induced Pluripotent Stem Cells as a Research Tool. PLoS ONE. 2016;11:e0158282 pubmed 出版商
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Gao Y, Lui W, Lee W, Cheng C. Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep. 2016;6:28589 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 1b
Velandia Romero M, Calderón Peláez M, Castellanos J. In Vitro Infection with Dengue Virus Induces Changes in the Structure and Function of the Mouse Brain Endothelium. PLoS ONE. 2016;11:e0157786 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 6
Campos Y, Qiu X, Gomero E, Wakefield R, Horner L, Brutkowski W, et al. Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier. Nat Commun. 2016;7:11876 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 5b
  • 免疫印迹; 人类; 图 5a
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez Carballo A, Gutierrez Uzquiza A, et al. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38? activation, while it impairs tumor growth through p38?-independent mechanisms. Oncotarget. 2016;7:45060-45078 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:25; 图 1
  • 免疫细胞化学; 小鼠; 1:25; 图 2
Bai H, Zhu Q, Surcel A, Luo T, Ren Y, Guan B, et al. Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization. Am J Physiol Gastrointest Liver Physiol. 2016;311:G396-411 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 3
  • 免疫组化-石蜡切片; 小鼠; 图 3
Lehner C, Gehwolf R, Ek J, Korntner S, Bauer H, Bauer H, et al. The blood-tendon barrier: identification and characterisation of a novel tissue barrier in tendon blood vessels. Eur Cell Mater. 2016;31:296-311 pubmed
  • 免疫组化; 小鼠; 图 s2
Baker L, BeGora M, Au Yeung F, Feigin M, Rosenberg A, Lowe S, et al. Scribble is required for pregnancy-induced alveologenesis in the adult mammary gland. J Cell Sci. 2016;129:2307-15 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3
Ding H, Xu Y, Gao D, Wang L. Glioma-associated oncogene homolog 1 promotes epithelial-mesenchymal transition in human renal tubular epithelial cell. Am J Transl Res. 2016;8:662-9 pubmed
  • 免疫细胞化学; pigs ; 图 3
  • 免疫印迹; pigs ; 1:1000; 图 3
  • 免疫细胞化学; 人类; 图 3
  • 免疫印迹; 人类; 1:1000; 图 3
Inada M, Izawa G, Kobayashi W, Ozawa M. 293 cells express both epithelial as well as mesenchymal cell adhesion molecules. Int J Mol Med. 2016;37:1521-7 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 3
Kim D, Glendining K, Grattan D, Jasoni C. Maternal Obesity in the Mouse Compromises the Blood-Brain Barrier in the Arcuate Nucleus of Offspring. Endocrinology. 2016;157:2229-42 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4
Guerrera D, Shah J, Vasileva E, Sluysmans S, Méan I, Jond L, et al. PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins. J Biol Chem. 2016;291:11016-29 pubmed 出版商
  • 免疫细胞化学; 犬; 图 3
Klinkert K, Rocancourt M, Houdusse A, Echard A. Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening. Nat Commun. 2016;7:11166 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4
  • 免疫印迹; 人类; 1:250; 图 4
Liu W, Cai H, Lin M, Zhu L, Gao L, Zhong R, et al. MicroRNA-107 prevents amyloid-beta induced blood-brain barrier disruption and endothelial cell dysfunction by targeting Endophilin-1. Exp Cell Res. 2016;343:248-257 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
Wardill H, Gibson R, Van Sebille Y, Secombe K, Logan R, Bowen J. A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options. Exp Biol Med (Maywood). 2016;241:1386-94 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:300; 图 7
  • 免疫印迹; 小鼠; 图 8
Falcão V, Maschio D, de Fontes C, Oliveira R, Santos Silva J, Almeida A, et al. Reduced insulin secretion function is associated with pancreatic islet redistribution of cell adhesion molecules (CAMS) in diabetic mice after prolonged high-fat diet. Histochem Cell Biol. 2016;146:13-31 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 2
Yang C, Demars K, Hawkins K, Candelario Jalil E. Adropin reduces paracellular permeability of rat brain endothelial cells exposed to ischemia-like conditions. Peptides. 2016;81:29-37 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:1000; 图 4
Davey C, Mathewson A, Moens C. PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration. PLoS Genet. 2016;12:e1005934 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2
Kuehn A, Kletting S, de Souza Carvalho Wodarz C, Repnik U, Griffiths G, Fischer U, et al. Human alveolar epithelial cells expressing tight junctions to model the air-blood barrier. ALTEX. 2016;33:251-60 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 8
Ji X, Liu Y, Hurd R, Wang J, Fitzmaurice B, Nishina P, et al. Retinal Pigment Epithelium Atrophy 1 (rpea1): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, θ. Invest Ophthalmol Vis Sci. 2016;57:877-88 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 8
Shukla P, Chaudhry K, Mir H, Gangwar R, Yadav N, Manda B, et al. Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. BMC Cancer. 2016;16:189 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:400; 图 1
Gebala V, Collins R, Geudens I, Phng L, Gerhardt H. Blood flow drives lumen formation by inverse membrane blebbing during angiogenesis in vivo. Nat Cell Biol. 2016;18:443-50 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 3
Kai T, Tsukamoto Y, Hijiya N, Tokunaga A, Nakada C, Uchida T, et al. Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway. J Pathol. 2016;239:97-108 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1.25 mg/ml; 图 4
McCabe M, Tarulli G, Laven Law G, Matthiesson K, Meachem S, McLachlan R, et al. Gonadotropin suppression in men leads to a reduction in claudin-11 at the Sertoli cell tight junction. Hum Reprod. 2016;31:875-86 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 3
Skardal A, Devarasetty M, Forsythe S, Atala A, Soker S. A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening. Biotechnol Bioeng. 2016;113:2020-32 pubmed 出版商
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产品类型 :
产品名称 :
目录# :
规格 :
价格 :
克隆性 :
纯度 :
宿主 :
反应物种 :
狗, 豚鼠, 人类, 小鼠, 大鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 5-10 µg/mL, Immunohistochemistry: 2-5 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 0.5-2 µg/mL
物种 :
狗, 豚鼠, 人类, 小鼠, 大鼠
抗体亚型 :
储存 :
描述 :
ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
免疫原 :
A 69 kD fusion protein(1) corresponding to amino acids 463-1109 of human ZO-1 cDNA.(2) This sequence lies N-terminal to the 80 amino acid region (the alpha-motif) present in the a+-isoform but absent in the a- isoform due to alternative splicing.
格式 :
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 5-10 µg/mL, Immunohistochemistry: 2-5 µg/mL, Immunoprecipitation: Assay-dependent, Western Blot: 0.5-2 µg/mL
别名 :
DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1
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公司总部: 美国