产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
粘着斑蛋白重组兔单克隆抗体(42H89L44)
目录 :
700062
规格 :
100微克
价格 :
美国425.00
克隆性 :
重组
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
42H89L44
反应物种 :
African green monkey, 人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 3b
Gong T, Heng B, Xu J, Zhu S, Yuan C, Lo E, et al. Decellularized extracellular matrix of human umbilical vein endothelial cells promotes endothelial differentiation of stem cells from exfoliated deciduous teeth. J Biomed Mater Res A. 2017;105:1083-1093 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2a
Gallego Delgado J, Basu Roy U, Ty M, Alique M, Fernandez Arias C, Movila A, et al. Angiotensin receptors and ?-catenin regulate brain endothelial integrity in malaria. J Clin Invest. 2016;126:4016-4029 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1a
  • 免疫细胞化学; African green monkey; 图 1b
Advani A, Chen A, Babbitt C. Human fibroblasts display a differential focal adhesion phenotype relative to chimpanzee. Evol Med Public Health. 2016;2016:110-6 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4
Heng B, Zhu S, Xu J, Yuan C, Gong T, Zhang C. Effects of decellularized matrices derived from periodontal ligament stem cells and SHED on the adhesion, proliferation and osteogenic differentiation of human dental pulp stem cells in vitro. Tissue Cell. 2016;48:133-43 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s3d
Brum A, van de Peppel J, van der Leije C, Schreuders Koedam M, Eijken M, van der Eerden B, et al. Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway. Proc Natl Acad Sci U S A. 2015;112:12711-6 pubmed 出版商
  • 免疫细胞化学; 人类
Richter E, Harms M, Ventz K, Gierok P, Chilukoti R, Hildebrandt J, et al. A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin. PLoS ONE. 2015;10:e0122089 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3
CURTIS J, Luo Y, Zenner H, Cuchet Lourenço D, Wu C, Lo K, et al. Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration. Nat Genet. 2015;47:523-527 pubmed 出版商
  • 免疫细胞化学; 人类
Rubashkin M, Cassereau L, Bainer R, DuFort C, Yui Y, Ou G, et al. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014;74:4597-611 pubmed 出版商
Betriu N, Jarrosson Moral C, Semino C. Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold. Biomolecules. 2020;10: pubmed 出版商
Liu Y, Xiao J, Zhang B, Shelite T, Su Z, Chang Q, et al. Increased talin-vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections. Lab Invest. 2020;100:1030-1041 pubmed 出版商
Gupte T, Ritt M, Dysthe M, Malik R, Sivaramakrishnan S. Minute-scale persistence of a GPCR conformation state triggered by non-cognate G protein interactions primes signaling. Nat Commun. 2019;10:4836 pubmed 出版商
Sosnowska M, Kutwin M, Jaworski S, Strojny B, Wierzbicki M, Szczepaniak J, et al. Mechano-signalling, induced by fullerene C60 nanofilms, arrests the cell cycle in the G2/M phase and decreases proliferation of liver cancer cells. Int J Nanomedicine. 2019;14:6197-6215 pubmed 出版商
Chen Y, Huang B, Lee W, Chen Y. 16-Hydroxycleroda-3,13-dien-15,16-olide induces anoikis in human renal cell carcinoma cells: involvement of focal adhesion disassembly and signaling. Onco Targets Ther. 2018;11:7679-7690 pubmed 出版商
Noethel B, Ramms L, Dreissen G, Hoffmann M, Springer R, Rübsam M, et al. Transition of responsive mechanosensitive elements from focal adhesions to adherens junctions on epithelial differentiation. Mol Biol Cell. 2018;29:2317-2325 pubmed 出版商
Wierzbicki M, Jaworski S, Kutwin M, Grodzik M, Strojny B, Kurantowicz N, et al. Diamond, graphite, and graphene oxide nanoparticles decrease migration and invasiveness in glioblastoma cell lines by impairing extracellular adhesion. Int J Nanomedicine. 2017;12:7241-7254 pubmed 出版商
Gentile P, McColgan Bannon K, Gianone N, Sefat F, Dalgarno K, Ferreira A. Biosynthetic PCL-graft-Collagen Bulk Material for Tissue Engineering Applications. Materials (Basel). 2017;10: pubmed 出版商
Patterson D, Roberts J, King V, Houserova D, Barnhill E, Crucello A, et al. Human snoRNA-93 is processed into a microRNA-like RNA that promotes breast cancer cell invasion. NPJ Breast Cancer. 2017;3:25 pubmed 出版商
Mekhdjian A, Kai F, Rubashkin M, Prahl L, Przybyla L, McGregor A, et al. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017;28:1467-1488 pubmed 出版商
Xu K, Babcock H, Zhuang X. Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton. Nat Methods. 2012;9:185-8 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
粘着斑蛋白重组兔单克隆抗体(42H89L44)
目录# :
700062
规格 :
100微克
价格 :
美国425.00
克隆性 :
重组单克隆
纯度 :
蛋白质A
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: 2-4 µg/1x10^6 cells, Immunocytochemistry: 0.5-5 µg/mL, Western Blot: 0.5-3 µg/mL
物种 :
人类, 小鼠
克隆 :
42H89L44
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions. It functions as one of several interacting proteins involved in anchoring F-actin to the membrane. It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques. In the assembly of adhesion plaques, the beta subunit of integrin binds to talin. Talin binds to vinculin that interacts with alpha-actinin and possibly with itself. Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system. Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.
免疫原 :
A recombinant protein corresponding to amino acids 408-591 of P18206.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 2-4 µg/1x10^6 cells, Immunocytochemistry: 0.5-5 µg/mL, Western Blot: 0.5-3 µg/mL
别名 :
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国