产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化AKT1(Ser473)重组兔单克隆抗体(98H9L8)
目录 :
700392
规格 :
100µg
价格 :
375.00美元
克隆性 :
重组
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
98H9L8
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 4
Rebolleda N, Losada Fernandez I, Perez Chacon G, Castejon R, Rosado S, Morado M, et al. Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model. PLoS ONE. 2016;11:e0154159 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 图 2
Zaldumbide L, Erramuzpe A, Guarch R, Pulido R, Cortés J, López J. Snail heterogeneity in clear cell renal cell carcinoma. BMC Cancer. 2016;16:194 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Seashore Ludlow B, Rees M, Cheah J, Cokol M, Price E, Coletti M, et al. Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset. Cancer Discov. 2015;5:1210-23 pubmed 出版商
  • 免疫印迹; 人类
Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Torres A, Nogueira C, Magalhães J, Costa I, Aragao A, Gomes Neto A, et al. Expression of EGFR and molecules downstream to PI3K/Akt, Raf-1-MEK-1-MAP (Erk1/2), and JAK (STAT3) pathways in invasive lung adenocarcinomas resected at a single institution. Anal Cell Pathol (Amst). 2014;2014:352925 pubmed 出版商
Chang R, Wang H, Bedi Y, Golding M. Preconception paternal alcohol exposure exerts sex-specific effects on offspring growth and long-term metabolic programming. Epigenetics Chromatin. 2019;12:9 pubmed 出版商
Liu S, Chen L, Xu Y. Significance of PYK2 level as a prognosis predictor in patients with colon adenocarcinoma after surgical resection. Onco Targets Ther. 2018;11:7625-7634 pubmed 出版商
Talebi A, Dehairs J, Rambow F, Rogiers A, Nittner D, Derua R, et al. Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy. Nat Commun. 2018;9:2500 pubmed 出版商
Ibrahim M, Scozzi D, Toth K, Ponti D, Kreisel D, Menna C, et al. Naive CD4+ T Cells Carrying a TLR2 Agonist Overcome TGF-β-Mediated Tumor Immune Evasion. J Immunol. 2018;200:847-856 pubmed 出版商
Cheng C, Jia K, Chen T, Chang S, Lin M, Yin H. Experimentally validated novel inhibitors of Helicobacter pylori phosphopantetheine adenylyltransferase discovered by virtual high-throughput screening. PLoS ONE. 2013;8:e74271 pubmed 出版商
Steketee M, Moysidis S, Jin X, Weinstein J, Pita Thomas W, Raju H, et al. Nanoparticle-mediated signaling endosome localization regulates growth cone motility and neurite growth. Proc Natl Acad Sci U S A. 2011;108:19042-7 pubmed 出版商
Castillo Rojas G, Cerbón M, Lopez Vidal Y. Presence of Helicobacter pylori in a Mexican Pre-Columbian Mummy. BMC Microbiol. 2008;8:119 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
磷酸化AKT1(Ser473)重组兔单克隆抗体(98H9L8)
目录# :
700392
规格 :
100µg
价格(美元) :
375.00美元
克隆性 :
重组单克隆
纯度 :
蛋白质A
宿主 :
反应物种 :
人类, 小鼠
应用 :
ELISA: 1-5 µg/mL, Flow Cytometry: 1-3 µg/1x10^6 cells, Immunocytochemistry: 1-2 µg, Immunofluorescence: 1-2 µg, Immunohistochemistry (Paraffin): 0.5-2 µg/mL, Western Blot: 1-3 µg/mL
物种 :
人类, 小鼠
克隆 :
98H9L8
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
免疫原 :
A peptide corresponding to amino acids 468-477 of P31749.
格式 :
液体
应用w/稀释 :
ELISA: 1-5 µg/mL, Flow Cytometry: 1-3 µg/1x10^6 cells, Immunocytochemistry: 1-2 µg, Immunofluorescence: 1-2 µg, Immunohistochemistry (Paraffin): 0.5-2 µg/mL, Western Blot: 1-3 µg/mL
别名 :
Akt; Akt kinase; AKT serine/threonine kinase 1; AKT/PKB; AKT1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006 gene product from transcript CG4006-RE; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dakt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel CG4006; Dmel_CG4006; DPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; p-Akt; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; Protein kinase B; protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; Rac; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; serine/threonine protein kinase; serine-threonine protein kinase; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国