产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化CDK4(Thr172)重组兔单克隆抗体(9H2L7)
目录 :
702556
规格 :
100微克
价格 :
美国500
克隆性 :
重组
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
9H2L7
反应物种 :
人类
应用 :
免疫细胞化学
更多信息或购买 :
文章摘录数: 1
产品信息
产品类型 :
抗体
产品名称 :
磷酸化CDK4(Thr172)重组兔单克隆抗体(9H2L7)
目录# :
702556
规格 :
100微克
价格 :
美国500
克隆性 :
重组单克隆
纯度 :
蛋白质A
宿主 :
兔
反应物种 :
人类
应用 :
Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL
物种 :
人类
克隆 :
9H2L7
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of the gene have been reported.
免疫原 :
Peptide corresponding to Human CDK4 (aa 169-175)
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL
别名 :
Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34. /cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)
更多信息或购买 :
公司信息
赛默飞世尔