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NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
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宿主 :
domestic rabbit
共轭标签 :
反应物种 :
cane toad, little skate, 人类, 小鼠, 大鼠, 斑马鱼, 家羊
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
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文章摘录数: 57
  • 免疫组化-冰冻切片; 小鼠; 1:300; 图 s8b
Barry D, Liu X, Liu B, Liu X, Gao F, Zeng X, et al. Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors. Nat Commun. 2020;11:1397 pubmed 出版商
  • 免疫组化; 小鼠; 1:300; 图 2b
Vigouroux R, Cesar Q, Chedotal A, Nguyen Ba Charvet K. Revisiting the role of Dcc in visual system development with a novel eye clearing method. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 1e'
Wang L, Xie J, Zhang H, Tsang L, Tsang S, Braune E, et al. Notch signalling regulates epibranchial placode patterning and segregation. Development. 2020;147: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 2a
Pan H, Fatima M, Li A, Lee H, Cai W, Horwitz L, et al. Identification of a Spinal Circuit for Mechanical and Persistent Spontaneous Itch. Neuron. 2019;103:1135-1149.e6 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 2b
Gutierrez Mecinas M, Bell A, Shepherd F, Polgár E, Watanabe M, Furuta T, et al. Expression of cholecystokinin by neurons in mouse spinal dorsal horn. J Comp Neurol. 2019;527:1857-1871 pubmed 出版商
  • 免疫组化-冰冻切片; little skate; 图 s1b
Jung H, Baek M, D Elia K, Boisvert C, Currie P, Tay B, et al. The Ancient Origins of Neural Substrates for Land Walking. Cell. 2018;172:667-682.e15 pubmed 出版商
  • 免疫组化-石蜡切片; cane toad; 图 12a
Smith R, Huang Y, Tian T, Vojtasova D, Mesalles Naranjo O, Pollard S, et al. The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk. J Neurosci. 2017;37:7975-7993 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 1b
Feng W, Kawauchi D, Körkel Qu H, Deng H, Serger E, Sieber L, et al. Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme. Nat Commun. 2017;8:14758 pubmed 出版商
  • 免疫组化; 小鼠; 1:50; 图 3e
Subashini C, Dhanesh S, Chen C, Riya P, Meera V, Divya T, et al. Wnt5a is a crucial regulator of neurogenesis during cerebellum development. Sci Rep. 2017;7:42523 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:1000; 图 5-s1a
Hachisuka J, Baumbauer K, Omori Y, Snyder L, Koerber H, Ross S. Semi-intact ex vivo approach to investigate spinal somatosensory circuits. elife. 2016;5: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:250; 图 2a
Kahn B, Corman T, Lovelace K, Hong M, Krauss R, Epstein D. Prenatal ethanol exposure in mice phenocopies Cdon mutation by impeding Shh function in the etiology of optic nerve hypoplasia. Dis Model Mech. 2017;10:29-37 pubmed 出版商
  • 免疫组化; 小鼠; 1:250; 图 s5g
Li Y, Tzatzalos E, Kwan K, Grumet M, Cai L. Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development. Sci Rep. 2016;6:38665 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 s2b
Dimidschstein J, Chen Q, Tremblay R, Rogers S, Saldi G, Guo L, et al. A viral strategy for targeting and manipulating interneurons across vertebrate species. Nat Neurosci. 2016;19:1743-1749 pubmed 出版商
  • 免疫组化; 小鼠; 图 2
Balázs A, Mészár Z, Hegedűs K, Kenyeres A, Hegyi Z, Dócs K, et al. Development of putative inhibitory neurons in the embryonic and postnatal mouse superficial spinal dorsal horn. Brain Struct Funct. 2017;222:2157-2171 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4m
Xu J, Liu H, Chai O, Lan Y, Jiang R. Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis. PLoS ONE. 2016;11:e0159597 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
  • 免疫细胞化学; 人类; 图 3
  • 免疫细胞化学; 小鼠; 图 5
Du C, Narayanan K, Leong M, Ibrahim M, Chua Y, Khoo V, et al. Functional Kidney Bioengineering with Pluripotent Stem-Cell-Derived Renal Progenitor Cells and Decellularized Kidney Scaffolds. Adv Healthc Mater. 2016;5:2080-91 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 1
Cai X, Kardon A, Snyder L, Kuzirian M, Minestro S, de Souza L, et al. Bhlhb5::flpo allele uncovers a requirement for Bhlhb5 for the development of the dorsal cochlear nucleus. Dev Biol. 2016;414:149-60 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 4
Wefers A, Lindner S, Schulte J, Schüller U. Overexpression of Lin28b in Neural Stem Cells is Insufficient for Brain Tumor Formation, but Induces Pathological Lobulation of the Developing Cerebellum. Cerebellum. 2017;16:122-131 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
Forbes M, Thornhill B, Galarreta C, Chevalier R. A population of mitochondrion-rich cells in the pars recta of mouse kidney. Cell Tissue Res. 2016;363:791-803 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:5
Madrigal M, Moreno Bravo J, Martínez López J, Martínez S, Puelles E. Mesencephalic origin of the rostral Substantia nigra pars reticulata. Brain Struct Funct. 2016;221:1403-12 pubmed 出版商
Chen S, Gao X, Zhou Y, Liu B, Liu X, Zhang Y, et al. A spinal neural circuitry for converting touch to itch sensation. Nat Commun. 2020;11:5074 pubmed 出版商
Browne T, Gradwell M, Iredale J, Maden J, Callister R, Hughes D, et al. Transgenic Cross-Referencing of Inhibitory and Excitatory Interneuron Populations to Dissect Neuronal Heterogeneity in the Dorsal Horn. Front Mol Neurosci. 2020;13:32 pubmed 出版商
Alharatani R, Ververi A, Beleza Meireles A, Ji W, Mis E, Patterson Q, et al. Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome. Hum Mol Genet. 2020;29:1900-1921 pubmed 出版商
Subramanian A, Sidhom E, Emani M, Vernon K, Sahakian N, Zhou Y, et al. Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation. Nat Commun. 2019;10:5462 pubmed 出版商
Paixão S, Loschek L, Gaitanos L, Alcalà Morales P, Goulding M, Klein R. Identification of Spinal Neurons Contributing to the Dorsal Column Projection Mediating Fine Touch and Corrective Motor Movements. Neuron. 2019;104:749-764.e6 pubmed 出版商
Boyle K, Gradwell M, Yasaka T, Dickie A, Polgár E, Ganley R, et al. Defining a Spinal Microcircuit that Gates Myelinated Afferent Input: Implications for Tactile Allodynia. Cell Rep. 2019;28:526-540.e6 pubmed 出版商
Verbitsky M, Westland R, Perez A, Kiryluk K, Liu Q, Krithivasan P, et al. The copy number variation landscape of congenital anomalies of the kidney and urinary tract. Nat Genet. 2019;51:117-127 pubmed 出版商
Gutierrez Mecinas M, Davis O, Polgár E, Shahzad M, Navarro Batista K, Furuta T, et al. Expression of Calretinin Among Different Neurochemical Classes of Interneuron in the Superficial Dorsal Horn of the Mouse Spinal Cord. Neuroscience. 2019;398:171-181 pubmed 出版商
Dickie A, Bell A, Iwagaki N, Polgár E, Gutierrez Mecinas M, Kelly R, et al. Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn. Pain. 2019;160:442-462 pubmed 出版商
Cerrato V, Parmigiani E, Figueres Oñate M, Betizeau M, Aprato J, Nanavaty I, et al. Multiple origins and modularity in the spatiotemporal emergence of cerebellar astrocyte heterogeneity. PLoS Biol. 2018;16:e2005513 pubmed 出版商
Wang L, Chen S, Ma H, Chen H, Hittelman W, Pan H. Regulating nociceptive transmission by VGluT2-expressing spinal dorsal horn neurons. J Neurochem. 2018;147:526-540 pubmed 出版商
Bowles J, Feng C, Ineson J, Miles K, Spiller C, Harley V, et al. Retinoic Acid Antagonizes Testis Development in Mice. Cell Rep. 2018;24:1330-1341 pubmed 出版商
Musah S, Dimitrakakis N, Camacho D, Church G, Ingber D. Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip. Nat Protoc. 2018;13:1662-1685 pubmed 出版商
Obana E, Zhou Q, Furmanski O, Doughty M. Conditional deletion of Neurog1 in the cerebellum of postnatal mice delays inhibitory interneuron maturation. J Neurosci Res. 2018;96:1560-1575 pubmed 出版商
Hachisuka J, Omori Y, Chiang M, Gold M, Koerber H, Ross S. Wind-up in lamina I spinoparabrachial neurons: a role for reverberatory circuits. Pain. 2018;159:1484-1493 pubmed 出版商
Wang D, Tawfik V, Corder G, Low S, Francois A, Basbaum A, et al. Functional Divergence of Delta and Mu Opioid Receptor Organization in CNS Pain Circuits. Neuron. 2018;98:90-108.e5 pubmed 出版商
Huang J, Polgár E, Solinski H, Mishra S, Tseng P, Iwagaki N, et al. Circuit dissection of the role of somatostatin in itch and pain. Nat Neurosci. 2018;21:707-716 pubmed 出版商
Gutierrez Mecinas M, Polgár E, Bell A, Herau M, Todd A. Substance P-expressing excitatory interneurons in the mouse superficial dorsal horn provide a propriospinal input to the lateral spinal nucleus. Brain Struct Funct. 2018;223:2377-2392 pubmed 出版商
Dawes J, Weir G, Middleton S, Patel R, Chisholm K, Pettingill P, et al. Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability. Neuron. 2018;97:806-822.e10 pubmed 出版商
Puri P, Schaefer C, Bushnell D, Taglienti M, Kreidberg J, Yoder B, et al. Ectopic Phosphorylated Creb Marks Dedifferentiated Proximal Tubules in Cystic Kidney Disease. Am J Pathol. 2018;188:84-94 pubmed 出版商
Boyle K, Gutierrez Mecinas M, Polgár E, Mooney N, O Connor E, Furuta T, et al. A quantitative study of neurochemically defined populations of inhibitory interneurons in the superficial dorsal horn of the mouse spinal cord. Neuroscience. 2017;363:120-133 pubmed 出版商
Mona B, Uruena A, Kollipara R, Ma Z, Borromeo M, Chang J, et al. Repression by PRDM13 is critical for generating precision in neuronal identity. elife. 2017;6: pubmed 出版商
Hagan N, Guarente J, Ellisor D, Zervas M. The Temporal Contribution of the Gbx2 Lineage to Cerebellar Neurons. Front Neuroanat. 2017;11:50 pubmed 出版商
Sarkar S, Bristow C, Dey P, Rai K, Perets R, Ramirez Cardenas A, et al. PRKCI promotes immune suppression in ovarian cancer. Genes Dev. 2017;31:1109-1121 pubmed 出版商
El Dahr S, Li Y, Liu J, Gutierrez E, Hering Smith K, Signoretti S, et al. p63+ ureteric bud tip cells are progenitors of intercalated cells. JCI Insight. 2017;2: pubmed 出版商
Cerqueira D, Bodnar A, Phua Y, Freer R, Hemker S, Walensky L, et al. Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development. FASEB J. 2017;31:3540-3554 pubmed 出版商
Hayano Y, Takasu K, Koyama Y, Yamada M, Ogawa K, Minami K, et al. Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B. J Exp Med. 2016;213:2949-2966 pubmed
Takasato M, Er P, Chiu H, Little M. Generation of kidney organoids from human pluripotent stem cells. Nat Protoc. 2016;11:1681-92 pubmed 出版商
Zemke M, Draganova K, Klug A, Schöler A, Zurkirchen L, Gay M, et al. Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. BMC Biol. 2015;13:103 pubmed 出版商
Takasato M, Er P, Chiu H, Maier B, Baillie G, Ferguson C, et al. Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature. 2015;526:564-8 pubmed 出版商
Shimada M, Dumitrache L, Russell H, McKinnon P. Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability. EMBO J. 2015;34:2465-80 pubmed 出版商
Jiang G, Dai M, Huang K, Chai G, Chen J, Chen L, et al. Neurochemical characterization of pERK-expressing spinal neurons in histamine-induced itch. Sci Rep. 2015;5:12787 pubmed 出版商
Zhang P, Ha T, Larouche M, Swanson D, Goldowitz D. Kruppel-Like Factor 4 Regulates Granule Cell Pax6 Expression and Cell Proliferation in Early Cerebellar Development. PLoS ONE. 2015;10:e0134390 pubmed 出版商
Thiebes K, Nam H, Cambronne X, Shen R, Glasgow S, Cho H, et al. miR-218 is essential to establish motor neuron fate as a downstream effector of Isl1-Lhx3. Nat Commun. 2015;6:7718 pubmed 出版商
Wainwright E, Wilhelm D, Combes A, Little M, Koopman P. ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation. Dev Biol. 2015;404:88-102 pubmed 出版商
Zuckermann M, Hovestadt V, Knobbe Thomsen C, Zapatka M, Northcott P, Schramm K, et al. Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling. Nat Commun. 2015;6:7391 pubmed 出版商
Vong K, Leung C, Behringer R, Kwan K. Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 pubmed 出版商
产品类型 :
产品名称 :
目录# :
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价格 :
克隆性 :
纯度 :
宿主 :
反应物种 :
Human, Mouse, Ovine, Rat, Xenopus laevis, Zebrafish
应用 :
ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
物种 :
Human, Mouse, Ovine, Rat, Xenopus laevis, Zebrafish
抗体亚型 :
储存 :
描述 :
The pax genes are a family of transcription factors that are active in specific tissues during early embryonic development. Pax family members possess a DNA-binding domain encoded by the paired box. Because paired domain containing genes encode transcription factors, they are capable of executing a genetic program. Several pax genes have also been associated with developmental mutations including: pax-3, which is associated with Waardenburg syndrome, pax-6, which is associated with Aniridia, and pax-2, which is associated with Wilms tumor. During embryogenesis, Pax-2 is expressed in the developing kidney. In particular, the pax-2 gene is expressed in condensing metanephric mesenchyme and in early epithelial structures derived from mesenchyme; however, pax-2 mRNA and protein levels are rapidly down regulated as the tubular epithelium matures. Although Pax-2 is down regulated during renal epithelium maturation, Pax-2 expression persists in the undifferentiated epithelium of Wilms' tumors. Persistent expression of Pax-2 in Wilms' tumors occurs frequently and correlates with the proliferation of poorly differentiated epithelial cells in these tumors. Interestingly, expression of the Wilms' tumor suppresser protein, WT1, coincides with down-regulation of the pax-2 gene; thus, suggesting that WT1 can directly repress pax-2 transcription.
免疫原 :
A GST-Pax-2 fusion protein derived from the C-terminal domain (aa188-385) of the murine Pax-2 protein
格式 :
应用w/稀释 :
ELISA: Assay-dependent, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
别名 :
FSGS7; Opdc; optic disc coloboma; paired box 2; paired box gene 2; paired box homeotic gene 2; paired box protein Pax-2; PAPRS; PAX2; Pax-2
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公司总部: 美国